TTX-MC138

Phase 2Small molecule

TTransCode Therapeutics

TTX-MC138 is one of 60 small molecule programs targeting HER2-positive Breast Cancer. It is currently in Phase 2.

Indications

Total Trials

Active Trials

Competitors

Pipeline

Status by Indication[3][1]

Indication

HER2-Positive Breast CancerRecruiting

Advanced Solid TumorsActive, not recruiting

HER2-Positive Breast CancerPreclinical

Recruiting

Advanced Solid TumorsPhase 2

Active, not recruiting

Competition

Competitive Landscape

286 competitors in Advanced Solid Tumors

#DrugCompanyPhaseTrials

Keytruda

Merck & Co.

Phase 2

47 2

Taxol

Teva

Phase 2

24 3

Opdivo

Bristol-Myers Squibb

Phase 2

18 4

Tecentriq

Roche

Phase 2

11 5

Taxotere

AAvyxa

Phase 2

23 6

Yervoy

Bristol-Myers Squibb

Phase 2

6 7

Platinol

MMcNeil Consumer & Specialty Pharmaceuticals, a Division of McNeil-PPC, Inc.

Phase 2

19 8

Braftovi

Pfizer

Phase 2

4 9

Erbitux

Sutent

Ranked by pipeline maturity and clinical activity. Current drug highlighted in teal.

Timeline

Expected Milestones

Q1 2027

Phase 1/2Active, not recruiting

Advanced Solid Tumors

NCT06260774

Q4 2031

PreclinicalRecruiting

HER2-Positive Breast Cancer

NCT05868226

Clinical

Trials by Indication[1]

Advanced Solid Tumors1 trial

Study of TTX-MC138 in Subjects With Advanced Solid Tumors

Active, not recruiting·TTransCode Therapeutics·Phase 1/2·NCT06260774·16 enrolled

HER2-positive Breast Cancer1 trial

PRE-Investigation of Serial Studies to Predict Your Therapeutic Response With Imaging And moLecular Analysis: A Phase I/II Platform Trial

Recruiting·QQuantumLeap Healthcare Collaborative·Preclinical·NCT05868226·280 enrolled

Sources

References

[1]
ClinicalTrials.gov — 2 trial records for TTX-MC138. U.S. National Library of Medicine, National Institutes of Health.
[2]
ChEMBL — TTX-MC138 compound record. European Bioinformatics Institute (EMBL-EBI).
[3]
Open Targets Platform — Drug–disease associations for TTX-MC138. EMBL-EBI & Wellcome Sanger Institute.
[4]
SEC EDGAR — TransCode Therapeutics company filings. U.S. Securities and Exchange Commission.

Details

Drug Info

Quick Facts

Modality: Small molecule[2]
Highest Phase: Phase 2[1]
Company: TTransCode Therapeutics

TTX-MC138

Status by Indication[3][1]

Competitive Landscape

Expected Milestones

Q1 2027

Q4 2031

Trials by Indication[1]

Advanced Solid Tumors1 trial

HER2-positive Breast Cancer1 trial

References

Drug Info

Quick Facts

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