Ubiquinol

Phase 2Small molecule

WWeill Medical College of Cornell University

Ubiquinol is one of 83 small molecule programs targeting Cardiac Arrest. It is currently in Phase 2.

Indications

Total Trials

Active Trials

Competitors

Pipeline

Status by Indication[3][1]

Indication

Cardiac ArrestActive, not recruiting

SepsisActive, not recruiting

Heart FailureActive, not recruiting

Cardiac ArrestPhase 2

Active, not recruiting

SepsisPhase 2

Active, not recruiting

Heart FailurePhase 2

Active, not recruiting

Competition

Competitive Landscape

687 competitors in Heart Failure

#DrugCompanyPhaseTrials

Bayer Aspirin

Bayer

Preclinical

2 2

Medrol

Pfizer

Preclinical

1 3

Amidate

Pfizer

Preclinical

1 4

LCZ696

Novartis

Preclinical

15 5

Ubiquinol

WWeill Medical College of Cornell University

Phase 2

1 6

Monoferric

PPharmacosmos A/S

Preclinical

5 7

Zoloft

VViatris Specialty LLC

Preclinical

2 8

Xylocaine

MMEDRx USA, Inc.

Preclinical

1 9

Adriamycin

GGynecologic Oncology Group

Sulfonylureas

Ranked by pipeline maturity and clinical activity. Current drug highlighted in teal.

Timeline

Expected Milestones

Q1 2027

Phase 2Recruiting

Study completion

NCT06555575

Clinical

Trials by Indication[1]

Cardiac Arrest1 trial

Ubiquinol as a Metabolic Resuscitator in Post-Cardiac Arrest

Completed·—·Phase 2·NCT02934555·48 enrolled

Gulf War Illness1 trial

Coenzyme Q10 Phase III Trial in Gulf War Illness

Completed·VVA Office of Research and Development·Phase 3·NCT02865460·100 enrolled

Parkinson's Disease1 trial

Ubiquinol in Parkinson's Disease: Safety, Tolerability, and Effects Upon Oxidative Damage and Mitochondrial Biomarkers

Completed·WWeill Medical College of Cornell University·Phase 2·NCT03061513·11 enrolled

Sepsis1 trial

Ubiquinol (Reduced COQ10) for Patients With Sepsis

Completed·—·Phase 2·NCT01948063·38 enrolled

Heart Failure1 trial

Ubiquinol Treatment in Patients With Heart Failure and Preserved Ejection Fraction

Unknown status·HHadassah Medical Organization·Phase 2·NCT02779634·60 enrolled

1 more indication

Unspecified1 trial

Ubiquinone vs. Ubiquinol Supplementation

Recruiting·TTrio Fertility·Phase 2·NCT06555575·90 enrolled

Sources

References

[1]
ClinicalTrials.gov — 6 trial records for Ubiquinol. U.S. National Library of Medicine, National Institutes of Health.
[2]
ChEMBL — Ubiquinol compound record. European Bioinformatics Institute (EMBL-EBI).
[3]
Open Targets Platform — Drug–disease associations for Ubiquinol. EMBL-EBI & Wellcome Sanger Institute.
[4]
SEC EDGAR — Weill Medical College of Cornell University company filings. U.S. Securities and Exchange Commission.

Details

Drug Info

Quick Facts

Modality: Small molecule[2]
Highest Phase: Phase 2[1]
Company: WWeill Medical College of Cornell University

Ubiquinol

Status by Indication[3][1]

Competitive Landscape

Expected Milestones

Q1 2027

Trials by Indication[1]

Cardiac Arrest1 trial

Gulf War Illness1 trial

Parkinson's Disease1 trial

Sepsis1 trial

Heart Failure1 trial

Unspecified1 trial

References

Drug Info

Quick Facts

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