Ziltivekimab

Pipeline

Status by Indication[3][1]

Competition

Competitive Landscape

Heart FailureCardiovascular DiseaseKidney DiseaseAcute Myocardial Infarction

687 competitors in Heart Failure

#DrugCompanyPhaseTrials

1

Ziltivekimab

Novo Nordisk

Phase 3

22

Brethine

Sanofi

Preclinical

13

Monoferric

PPharmacosmos A/S

Preclinical

54

Zemplar

AbbVie

Preclinical

—5

Bystolic

VVitae Pharmaceuticals Inc., an Allergan affiliate

Preclinical

46

Zoloft

VViatris Specialty LLC

Preclinical

27

Coumadin

AAbbott

Preclinical

18

Tamiflu

CConrado Roberto Hoffmann Filho

Preclinical

19

Oraverse

LLife Extension Foundation Inc.

Preclinical

110

Statin

Bristol-Myers Squibb

Preclinical

1Show 17 more competitors

Ranked by pipeline maturity and clinical activity. Current drug highlighted in teal.

Timeline

Expected Milestones

Clinical

Trials by Indication[1]

Heart Attack2 trials

A Research Study to Look at the Effect of Ziltivekimab on Plaque in the Blood Vessels of the Heart, Compared to Placebo, in People With a Heart Attack

Recruiting·Novo Nordisk·Phase 3·NCT07301034·332 enrolled

ARTEMIS - A Research Study to Look at How Ziltivekimab Works Compared to Placebo in People With a Heart Attack

Recruiting·Novo Nordisk·Phase 3·NCT06118281·10,000 enrolled

Heart Failure2 trials

A Research Study Looking Into How Ziltivekimab Works Compared to Placebo in Participants With Heart Failure and Inflammation

Recruiting·Novo Nordisk·Phase 3·NCT06200207·680 enrolled

Effects of Ziltivekimab Versus Placebo on Morbidity and Mortality in Patients With Heart Failure With Mildly Reduced or Preserved Ejection Fraction and Systemic Inflammation

Active, not recruiting·Novo Nordisk·Phase 3·NCT05636176·4,899 enrolled

Chronic Renal Disease2 trials

Trial to Evaluate Reduction in Inflammation in Patients With Advanced Chronic Renal Disease Utilizing Antibody Mediated IL-6 Inhibition

Completed·Novo Nordisk·Phase 2·NCT03926117·264 enrolled

Trial to Evaluate Reduction in Inflammation in Patients With Advanced Chronic Renal Disease Utilizing Antibody Mediated IL-6 Inhibition in Japan.

Completed·Novo Nordisk·Phase 2·NCT04626505·36 enrolled

Kidney Disease1 trial

A Research Study of How the Medicine Ziltivekimab Works in the Body of Chinese Men and Women With Kidney Disease and Inflammation

Completed·Novo Nordisk·Phase 1·NCT05379829·24 enrolled

LAM1 trial

Specifying the Anti-inflammatory Effects of Ziltivekimab

Recruiting·—·Phase 3·NCT06263244·40 enrolled

3 more indications

Cardiovascular Disease1 trial

ZEUS - A Research Study to Look at How Ziltivekimab Works Compared to Placebo in People With Cardiovascular Disease, Chronic Kidney Disease and Inflammation

Active, not recruiting·Novo Nordisk·Phase 3·NCT05021835·6,200 enrolled

Acute Myocardial Infarction1 trial

Effects of Ziltivekimab on Coronary Atherosclerotic Burden in Patients With Acute Myocardial Infarction

Recruiting·EECRI bv·Phase 3·NCT07276282·332 enrolled

Unspecified1 trial

A Research Study Looking Into Blood Levels of Three Different Formulations of the Study Medicine Ziltivekimab

Completed·Novo Nordisk·Phase 1·NCT05721989·267 enrolled

Details

Drug Info

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