VivoSeq
Other

Acute Pain

4

Pipeline Programs↗

13

Active Trials↗

7

Companies Involved↗

Acute Pain is an early-stage landscape with 4 programs across 7 companies. The most active players are AFT Pharmaceuticals, Ltd., Pfizer's Upjohn has merged with Mylan to form Viatris Inc., Eli Lilly.

Intelligence

Pipeline Metrics

Competitive Density

37/100

Pipeline Velocity

27/100

Mech. Concentration

33/100

Completion Rate

90/100

Attrition Rate

7/100

Competition

Competitive Landscape

Bubble size = clinical trials

Approved
Phase 3
Phase 2
Phase 1
Preclinical

Key Players

Top Companies Companies ranked by the number of pipeline programs they run for this disease.

A

AFT Pharmaceuticals, Ltd.

1 program

Phase 3P

Pfizer's Upjohn has merged with Mylan to form Viatris Inc.

1 program

PreclinicalEli Lilly logo

Eli Lilly

1 program

PreclinicalAlnylam Pharmaceuticals logo

Alnylam Pharmaceuticals

1 program

PreclinicalT

Tris Pharma, Inc.

0 programs

PreclinicalJohnson & Johnson logo

Johnson & Johnson

0 programs

Preclinical

Pipeline

Programs by Phase

Analysis

Trial Status

44

clinical trials

Completed26 · 59%
Not yet recruiting7 · 16%
Recruiting6 · 14%
Terminated3 · 7%
Unknown status2 · 5%

Clinical Trials

Trial Activity

44 trials

ESKetamine Low-dose vs Ketamine Low-dose for Severe Acute Pain in Emergency Units, Comparison of PsychodyslEptic Effects
Recruiting·—·Phase 4·NCT06853041·74 enrolled
Nebulized Ketamine to Nebulized Fentanyl for Treating Acute Painful Conditions in the ED
Recruiting·—·Phase 4·NCT06364540·150 enrolled
Rebooting Infant Pain Care: Using Machine Learning and Skin-to-Skin Contact to Exponentially Improve Neonatal Intensive Care Unit Practice
Recruiting·York University·N/A·NCT05579496·400 enrolled
The Influence of Vasopressin on Observational Learning of Placebo Analgesia
Recruiting·UUniversity of Maryland, Baltimore·Preclinical·NCT03446456·56 enrolled
Effectiveness of Retrolaminar Block in Reducing Postoperative Opioid Consumption in Patients Undergoing Lumbar Spine Fusion With Multimodal Analgesia
Recruiting·PPontificia Universidad Catolica de Chile·Preclinical·NCT07291388·44 enrolled
Myogenous Face Pain Following Third Molar Extractions Under Intravenous Sedation
Recruiting·RRutgers, The State University of New Jersey·Phase 2·NCT04880707·48 enrolled
A Non-randomised, Non-inferiority Comparative Study of Oral Actiskenan (Morphine Sulfate) Versus Intranasal Sufentanil in the Early Management of Severe Acute Pain in Emergency Departments.
Not yet recruiting·GGroupe Hospitalier de la Region de Mulhouse et Sud Alsace·N/A·NCT07344350·400 enrolled
Sequential Method Determination of Oxycodone for Thoracoscope Surgery Median Effective Dose of Acute Pain Treatment
Not yet recruiting·—·N/A·NCT06534801·60 enrolled
Pharmacokinetic Study of the Use of Nefopam 30 mg Tablets in Patients Suffering From Acute Pain in Rheumatology
Not yet recruiting·UUniversity Hospital, Rouen·Phase 4·NCT07491393·24 enrolled
A Pilot Study for Developing a Comprehensive Signal Detection Approach for the Mechanisms of Action and Analgesic Efficacy of Two Analgesics Using Human Experimental Models of Pain (HEMP)
Not yet recruiting·NNational Center for Complementary and Integrative Health (NCCIH)·Preclinical·NCT07549490·25 enrolled
Postoperative Outcomes of Regional Blocks Performed in Cervical Disc Surgery: A Prospective Observational Study
Not yet recruiting·Samsun University·N/A·NCT07694180·66 enrolled
Anterior Versus Posterior Versus Lateral Quadratus Lumborum Block: a Randomized Control Trial in Healthy Volunteers
Not yet recruiting·DDuke University·Approved·NCT07566312·25 enrolled
An Open Label, Pharmacokinetic and Safety Study of Combogesic® IV in Pediatric Patients With Acute Pain
Not yet recruiting·AAFT Pharmaceuticals, Ltd.·Phase 3·NCT07225634·60 enrolled
Low Dose Ketamine and Acute Pain Crisis
Completed·RRhode Island Hospital·Phase 4·NCT04330183·20 enrolled
Genetic Basis For Variation In NSAID Analgesia In A Clinical Model Of Acute Pain
Completed·National Institute of Nursing Research (NINR)·Phase 2·NCT00115752·96 enrolled
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Data sources: ClinicalTrials.gov (NIH) · OpenFDA (FDA) · ChEMBL (EMBL-EBI) · Open Targets (EBI/Sanger) · MedlinePlus (NIH) · PubMed (NIH) · SEC EDGAR (SEC)