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Ophthalmology/Cataract

Cataract

34

Pipeline Programs↗

72

Active Trials↗

33

Companies Involved↗

Cataract is a moderately active landscape with 34 programs across 33 companies. 6 programs are in Phase 3.

Intelligence

Pipeline Metrics

Competitive Density

64/100

Pipeline Velocity

69/100

Mech. Concentration

22/100

Completion Rate

88/100

Attrition Rate

8/100

Pipeline

Programs by Phase

Preclinical26

Norepinephrine

General Hospital of Ningxia Medical University

Triamcinolone

Bassett Healthcare

Bimatoprost

AbbVie

Epinephrine

Samson Clinical Operations Pty Ltd

Fentanyl

Cephalon

Phase 11

EO2002

Asociación para Evitar la Ceguera en México

Phase 21

Taurine

Third Military Medical University

Phase 36

Ripasudil

Kowa Research Institute, Inc.

Clobetasol Propionate

Bayer

Xanax

Orion Corporation, Orion Pharma

Idose TR

Glaukos Corporation

Systane Complete

National Taiwan University Hospital

Approved

No programs

Analysis

Trial Status

314

clinical trials

Completed193 · 61%

Recruiting37 · 12%

Not yet recruiting26 · 8%

Unknown status23 · 7%

Terminated17 · 5%

Active, not recruiting9 · 3%

Other9 · 3%

Clinical Trials

Trial Activity

314 trials

Capella Scientia (SCDX) Development Study

Recruiting·AAlcon Research·N/A·NCT06987474·400 enrolled

Ocular Anatomical Parameters in Patients Undergoing Anterior Segment Surgery Based on Swept-Source Optical Coherence Tomography: An Observational Study

Recruiting·NNanfang Hospital, Southern Medical University·N/A·NCT07903454·500 enrolled

Surgical Procedure Efficiency Evaluation stuDy (SPEED): Combination Phaco-Vitrectomy Surgeries With UNITY VCS vs. Constellation in a Real-World Operating Room Setting

Recruiting·AAlcon Research·N/A·NCT07228091·180 enrolled

EVALUATION OF MILOOP LENS FRAGMENTATION DEVICE IN PHACOEMULSIFICATION FOR DENSE CATARACTS: A RANDOMIZED CONTROLLED TRIAL

Recruiting·UUniversiti Kebangsaan Malaysia Medical Centre·Preclinical·NCT07898007·68 enrolled

Evaluating the Efficacy, Compliance, and Patient Satisfaction of a New Dropless Postoperative Regimen After Cataract Surgery in a Vulnerable, County-hospital Population

Recruiting·UUniversity of California, San Francisco·Approved·NCT05157113·70 enrolled

"Comparative Study of High-frequency Pulsed Vacuum Technology Versus Phacoemulsification for Cataract Surgery

Recruiting·—·Preclinical·NCT07074431·60 enrolled

Randomized Controlled Trial of the STEIN Protocol: A Neuroplastic Pain Education and Guided Breathing Intervention During Awake Cataract Surgery

Recruiting·UUniversity of California, Los Angeles·Preclinical·NCT07715591·300 enrolled

A Prospective, Randomized, Subject and Vision-assessor Masked, Multicenter Study Comparing Bilateral Clareon PanOptix, Bilateral Clareon PanOptix Pro, and Mixed Clareon PanOptix Pro/Vivity Intraocular Lens Implantation in Cataract Subjects

Recruiting·BBerkeley Eye Center·Approved·NCT06922084·320 enrolled

Pilot Study: Feasibility and Usability of a Head-Mounted Spatial Computing Device for Intraoperative Visualization During Intraocular Surgery

Recruiting·—·N/A·NCT07825337·70 enrolled

Postoperative Outcomes of a Toric Add-On Intraocular Lens After Keratoplasty and Cataract Surgery

Recruiting·MMedical University of Vienna·N/A·NCT07452042·40 enrolled

Visual and Patient Reported Outcomes Comparing Clareon TruPlus IOL and Tecnis Eyhance IOLs in Normal Cataract Patients: Stage 1

Recruiting·GGainesville Eye Associates·N/A·NCT07658040·70 enrolled

Investigation of Guangke Lenses' Efficacy in Delaying Myopia Onset/Progression in Postoperative Congenital Cataract Children

Recruiting·EEye & ENT Hospital of Fudan University·Preclinical·NCT07778797·50 enrolled

Evaluation of Lacrifill™ Canalicular Filler for Optimization of Ocular Surface Parameters and Biometric Precision in Prospective Cataract Surgery Patients With Dry Eye Disease

Recruiting·TThe Eye Institute of West Florida·N/A·NCT07648095·65 enrolled

Evaluation of Visual Adaptation and Optical Performance in Patients With Bilateral Multifocal or Mix-and-Match Intraocular Lens Implantation: A Longitudinal Observational Study

Recruiting·SSichuan Academy of Medical Sciences·N/A·NCT07740590·264 enrolled

Single-site, Open-label, Prospective Feasibility Study Performed Using the JASPER™ Robotic Surgical System in Cataract Surgery Procedures

Recruiting·FForSight Robotics Ltd·Preclinical·NCT07468409·40 enrolled

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Data sources: ClinicalTrials.gov (NIH) · OpenFDA (FDA) · ChEMBL (EMBL-EBI) · Open Targets (EBI/Sanger) · MedlinePlus (NIH) · PubMed (NIH) · SEC EDGAR (SEC)