VivoSeq
Other

Chemotherapy-Induced Nausea and Vomiting

49

Pipeline Programs↗

7

Active Trials↗

22

Companies Involved↗

Chemotherapy-induced nausea and vomiting is a moderately active landscape with 49 programs across 22 companies. The most active players are Eisai, Validus Pharmaceuticals, Haisco Pharmaceutical Group Co., Ltd.. 12 therapies are approved with 23 more in late-stage development.

Intelligence

Pipeline Metrics

Competitive Density

60/100

Pipeline Velocity

11/100

Mech. Concentration

19/100

Completion Rate

90/100

Attrition Rate

7/100

Competition

Competitive Landscape

Bubble size = clinical trials

Approved
Phase 3
Phase 2
Phase 1
Preclinical

Key Players

Top Companies Companies ranked by the number of pipeline programs they run for this disease.

Eisai logo

Eisai

1 program

Phase 2V

Validus Pharmaceuticals

1 program

Phase 2Haisco Pharmaceutical Group Co., Ltd. logo

Haisco Pharmaceutical Group Co., Ltd.

1 program

Phase 2S

Solasia Pharma K.K.

1 program

Phase 3Qilu Pharmaceutical Co., Ltd. logo

Qilu Pharmaceutical Co., Ltd.

1 program

Phase 3S

Solvay Pharmaceuticals

1 program

Phase 3

Pipeline

Programs by Phase

Analysis

Trial Status

54

clinical trials

Completed37 · 69%
Unknown status6 · 11%
Recruiting4 · 7%
Not yet recruiting3 · 6%
Terminated3 · 6%
Withdrawn1 · 2%

Clinical Trials

Trial Activity

54 trials

Electroacupuncture Plus Antiemetic Therapy for Chemotherapy-Induced Nausea and Vomiting in Patients With Breast Cancer
Recruiting·—·Phase 3·NCT06314906·370 enrolled
Study With IV NEPA (Fosnetupitant/Palonosetron) for the Prevention of Chemotherapy-induced Nausea and Vomiting in Paediatric Cancer Patients Undergoing Highly Emetogenic Chemotherapy (HEC)
Recruiting·HHelsinn Healthcare SA·Phase 2·NCT06904235·95 enrolled
Ondansetron (ODF) Versus Ondansetron Intravenously for the Prevention of Chemotherapy-induced Nausea and Vomiting Compare in Children
Recruiting·—·Phase 3·NCT06208917·376 enrolled
Electroacupuncture for the Prevention of Chemotherapy-induced Nausea and Vomiting in Patients With Breast Cancer
Recruiting·—·Phase 3·NCT06200168·370 enrolled
Nano-crystalline Megestrol Acetate for Chemotherapy-induced Nausea and Vomiting
Not yet recruiting·—·Phase 2·NCT07246070·127 enrolled
Evaluating the Efficacy and Safety of HSK21542 Injection in Chemotherapy-induced Nausea and Vomiting
Not yet recruiting·FFirst Affiliated Hospital of Wenzhou Medical University·Phase 2·NCT06593782·180 enrolled
Nanocrystalline Megestrol for Managing Chemotherapy-Induced Nausea and Vomiting
Not yet recruiting·TThe First Affiliated Hospital of Xinxiang Medical College·Phase 3·NCT07124195·126 enrolled
Study of Aprepitant / Fosaprepitant for the Prevention of Chemotherapy-induced Nausea and Vomiting (CINV) in Colorectal Cancer Patients - SENRI Trial
Completed·MMulticenter Clinical Study Group of Osaka, Colorectal Cancer Treatment Group·N/A·NCT01344304·413 enrolled
Olanzapine for Prevention of Chemotherapy-induced Nausea and Vomiting in Children: A Multi-Centre Feasibility Study
Completed·TThe Hospital for Sick Children·Phase 2·NCT02129478·15 enrolled
Safety and Efficacy of Palonosetron in Preventing Chemotherapy-induced Nausea and Vomiting
Completed·HHangzhou Jiuyuan Gene Engineering Co. Ltd.,·Phase 2·NCT00503386·144 enrolled
Phase 4 Trial to Evaluate the Efficacy and Safety of Sancuso Patch in Chemotherapy-induced Nausea and Vomiting Associated With the Administration of Highly Emetogenic Chemotherapy (HEC)
Completed·LLG Life Sciences·Phase 4·NCT01659775·389 enrolled
Acupuncture for Chemotherapy-Induced Nausea and Vomiting
Completed·TTianjin University of Traditional Chinese Medicine·N/A·NCT02195921·160 enrolled
Aprepitant ,Olanzapine,Palonosetron and Dexamethasone for the Prevention of Chemotherapy-induced Nausea and Vomiting
Completed·FFirst Affiliated Hospital of Harbin Medical University·Phase 3·NCT02484911·120 enrolled
The Different Effectiveness of Single Acupoint（PC6 or CV12) vs Matching Acupoints(PC6 and CV12) in Chemotherapy-induced Nausea and Vomiting
Completed·TTianjin University of Traditional Chinese Medicine·N/A·NCT02195908·160 enrolled
Auricular Acupressure for Chemotherapy-Induced Nausea and Vomiting in Female Breast Cancer Patients
Completed·TThe Hong Kong Polytechnic University·N/A·NCT02403037·114 enrolled
Page 1 of 4

Data sources: ClinicalTrials.gov (NIH) · OpenFDA (FDA) · ChEMBL (EMBL-EBI) · Open Targets (EBI/Sanger) · MedlinePlus (NIH) · PubMed (NIH) · SEC EDGAR (SEC)