Decadron

(dexamethasone)

ApprovedSmall molecule

Dexamethasone is a steroid medication used to reduce inflammation and suppress the immune system in conditions like arthritis, allergies, asthma, and certain cancers. It's also used to reduce swelling in the brain and to help manage severe COVID-19 symptoms.[2] Decadron is currently approved and in use across 382 indications[4].[1]

Decadron is one of 2814 small molecule programs targeting Total Knee Arthroplasty. It is currently in Approved.

382

Indications

2,348

Total Trials

Active Trials

2,813

Competitors

FDA Applications

NDA/BLA/ANDA regulatory filings

Patents

Pipeline

Status by Indication[4][1]

Indication

Total Knee ArthroplastyUnknown status

LeukemiaCompleted

AmyloidosisCompleted

PlasmacytomaActive, not recruiting

PulpitisUnknown status

Immune ThrombocytopeniaCompleted

Hearing LossCompleted

HypotensionActive, not recruiting

Idiopathic ScoliosisActive, not recruiting

KeratoconjunctivitisActive, not recruiting

Total Knee ArthroplastyApproved

Unknown status

LeukemiaPhase 3

Completed

AmyloidosisPhase 3

Completed

PlasmacytomaPhase 3

Active, not recruiting

PulpitisPhase 1

Unknown status

Immune ThrombocytopeniaApproved

Completed

Hearing LossApproved

Completed

HypotensionApproved

Active, not recruiting

Idiopathic ScoliosisApproved

Active, not recruiting

KeratoconjunctivitisApproved

Active, not recruiting

Showing 10 of 373 indications

Competition

Competitive Landscape

702 competitors in Breast Cancer

#DrugCompanyPhaseTrials

Decadron

AAspen Global Incorporated

Approved

12 2

Adenocard

Astellas

Preclinical

2 3

Lexiscan

Astellas

Preclinical

1 4

Voltaren

Novartis

Preclinical

1 5

Zolymbus

AbbVie

Preclinical

1 6

Blenoxane

Bristol-Myers Squibb

Preclinical

1 7

Methylthioninium Chloride

PProvepharm SAS

Preclinical

3 8

MS Contin

HHikma Pharmaceuticals LLC

Preclinical

3 9

Duragesic

CCephalon

Preclinical

1 10

Cortef

PPfizer's Upjohn has merged with Mylan to form Viatris Inc.

Preclinical

Ranked by pipeline maturity and clinical activity. Current drug highlighted in teal.

Timeline

Expected Milestones

Q4 2026

Post-ApprovalActive, not recruiting

Multiple Myeloma

NCT03173092

Phase 1Active, not recruiting

Multiple Myeloma

NCT05560399

Phase 1/2Recruiting

Acute Lymphoblastic Leukemia

NCT06207123

Post-ApprovalNot yet recruiting

Efficacy and Safety

NCT07482891

Q1 2027

N/ARecruiting

Dexmedetomidine

NCT07289620

Phase 2Recruiting

Multiple Myeloma

NCT04508790

Clinical

Trials by Indication[1]

Multiple Myeloma48 trials

Expanded Access Program:Lenalidomide With or Without Dexamethasone In Previously Treated Subjects With Multiple Myeloma

Completed· Bristol-Myers Squibb logo

Bristol-Myers Squibb·Phase 3·NCT00179647·1,913 enrolled

Carfilzomib, Pomalidomide, and Dexamethasone in Treating Patients With Relapsed or Refractory Multiple Myeloma

Completed·UUniversity of Chicago·Phase 1/2·NCT01665794·25 enrolled

Safety Study of Dasatinib With Bortezomib (Velcade®) and Dexamethasone for Multiple Myeloma

Terminated· Bristol-Myers Squibb logo

Bristol-Myers Squibb·Phase 1·NCT00560352·16 enrolled

Show 45 more trials

STUDY THAT COMPARE 3 ARM: MLN9708 DEXAMETHASONE, MLN9708 CYCLOPHOSPHAMIDE AND DEXAMETHASONE, MLN9708 THALIDOMIDE AND DEXAMETHASONE FOLLOWED BY MAINTENANCE WITH MLN9708 IN NEWLY DIAGNOSED ELDERLY MULTIPLE MYELOMA PATIENTS

Completed·MMario Boccadoro·Phase 2·NCT02586038·175 enrolled

Study Comparing Daratumumab, Lenalidomide, Bortezomib, and Dexamethasone (D-RVd) Versus Lenalidomide, Bortezomib, and Dexamethasone (RVd) in Subjects With Newly Diagnosed Multiple Myeloma

Completed· Johnson & Johnson logo

Johnson & Johnson·Phase 2·NCT02874742·224 enrolled

Mezigdomide and Elranatamab for Relapsed and/or Refractory Multiple Myeloma

Recruiting·YYOUNGIL KOH·Phase 1/2·NCT06645678·75 enrolled

A Study of Iberdomide (CC-220) in Combination With Elotuzumab and Dexamethasone for Relapsed/Refractory Multiple Myeloma

Active, not recruiting·IIcahn School of Medicine at Mount Sinai·Phase 1·NCT05560399·7 enrolled

STUDY COMPARING TWO STANDARD TREATMENTS IN AUTOLOGOUS STEM CELL TRANSPLANTATION INELIGIBLE POPULATION AFFECTED BY MULTIPLE MYELOMA

Active, not recruiting·UUniversity of Turin, Italy·Phase 4·NCT03829371·450 enrolled

Phase 1/2 Study of VELCADE® in Combination With Other Drugs to Treat Previously Untreated Multiple Myeloma Patients

Completed· Takeda logo

Takeda·Phase 1/2·NCT00507442·158 enrolled

Lenalidomide and Dexamethasone With/Without Stem Cell Transplant in Patients With Multiple Myeloma

Completed·—·Phase 4·NCT01731886·60 enrolled

A Study of Tabalumab (LY2127399) in Participants With Previously Treated Multiple Myeloma (MM)

Completed· Eli Lilly logo

Eli Lilly·Phase 2·NCT01602224·220 enrolled

Study Comparing Carfilzomib, Lenalidomide, and Dexamethasone (CRd) vs Lenalidomide and Dexamethasone (Rd) in Subjects With Relapsed Multiple Myeloma

Completed· Amgen logo

Amgen·Phase 3·NCT01080391·792 enrolled

Testing JNJ-42756493 In Combination With Dexamethasone in Multiple Myeloma That Came Back After a Period of Improvement

Terminated·UUniversity Health Network, Toronto·Phase 2·NCT02952573·20 enrolled

Safety and Efficacy of Melflufen and Dexamethasone in Relapsed and/or Relapsed-Refractory Multiple Myeloma Patients

Terminated·OOncopeptides AB·Phase 1/2·NCT01897714·75 enrolled

S0417 Bortezomib, Thalidomide, and Dexamethasone in Treating Patients With Relapsed or Refractory Multiple Myeloma

Terminated·SSWOG Cancer Research Network·Phase 2·NCT00124579·7 enrolled

A Safety and Efficacy Study of Carfilzomib and Pomalidomide With Dexamethasone in Patients With Relapsed or Refractory Multiple Myeloma

Terminated·CCriterium, Inc.·Phase 1/2·NCT01464034·136 enrolled

Arsenic Trioxide, Ascorbic Acid, Dexamethasone, and Thalidomide in Treating Patients With Multiple Myeloma

Withdrawn·TThe Cleveland Clinic·Phase 2·NCT00112879

Dinaciclib, Bortezomib, and Dexamethasone in Treating Patients With Relapsed Multiple Myeloma

Completed·NNational Cancer Institute (NCI)·Phase 1·NCT01711528·41 enrolled

Doxorubicin Hydrochloride Liposome, Bortezomib, and Dexamethasone in Treating Patients With Newly Diagnosed Multiple Myeloma

Unknown status·OOncotherapeutics·Phase 2·NCT00742404·35 enrolled

Iberdomide Alone or in Combination With Dexamethasone for the Treatment of Intermediate- or High-Risk Smoldering Multiple Myeloma

Recruiting·EEmory University·Phase 2·NCT04776395·68 enrolled

A Phase I-Ib/II Study to Determine the Maximum Tolerated Dose (MTD) of AUY922 Alone and in Combination With Bortezomib, With or Without Dexamethasone, in Patients With Relapsed or Refractory Multiple Myeloma.

Completed· Novartis logo

Novartis·Phase 1/2·NCT00708292·29 enrolled

Selinexor and Lenalidomide for Consolidation and Maintenance Treatment in Multiple Myeloma Post-transplant

Withdrawn·WWashington University School of Medicine·Phase 2·NCT05820763

A Study of Weekly Carfilzomib in Combination With Dexamethasone for Progressive Multiple Myeloma

Completed· Amgen logo

Amgen·Phase 1/2·NCT01677858·116 enrolled

Iberdomide, Daratumumab, Carfilzomib, and Dexamethasone (Iber-KDd) in Patients With Relapsed/Refractory Multiple Myeloma

Recruiting·—·Phase 2·NCT05896228·30 enrolled

A Study of Ixazomib (NINLARO®) in Combination With Lenalidomide and Dexamethasone (IRD) for the Treatment of Participants With Multiple Myeloma (MM)

Active, not recruiting· Takeda logo

Takeda·Phase 4·NCT03173092·141 enrolled

Mezigdomide Plus Ixazomib and Dexamethasone for Relapsed and Refractory Multiple Myeloma

Withdrawn·KKathleen Dorritie·Phase 1/2·NCT06050512

An Investigational Immuno-therapy Study of Nivolumab, Pomalidomide and Dexamethasone Combinations in Patients With Multiple Myeloma

Completed· Bristol-Myers Squibb logo

Bristol-Myers Squibb·Phase 3·NCT02726581·170 enrolled

Idasanutlin, Ixazomib Citrate, and Dexamethasone in Treating Patients With Relapsed Multiple Myeloma

Completed·MMayo Clinic·Phase 1/2·NCT02633059·33 enrolled

Evaluate the Safety, Tolerability, and Efficacy of ICP-490 in Patients With Relapsed and/or Refractory Multiple Myeloma

Recruiting·BBeijing InnoCare Pharma Tech Co., Ltd.·Phase 1/2·NCT05719701·80 enrolled

Early Patient Access Single Named Patient Program for the Use of Ulocuplumab for the Treatment of Multiple Myeloma

No longer available·—··NCT02666209

Pembrolizumab, Ixazomib Citrate, and Dexamethasone in Treating Patients With Relapsed Multiple Myeloma

Completed·MMayo Clinic·Phase 2·NCT03506360·13 enrolled

A Study of the Safety and Efficacy of CNTO 328 and Bortezomib to Bortezomib Alone in Patients With Relapsed or Refractory Multiple Myeloma

Completed· Johnson & Johnson logo

Johnson & Johnson·Phase 2·NCT00401843·307 enrolled

Efficacy and Safety Study of 3 Thalidomide Doses for the Treatment of Relapsed Refractory Multiple Myeloma

Completed· Bristol-Myers Squibb logo

Bristol-Myers Squibb·Phase 3·NCT00452569·499 enrolled

Delanzomib (CEP-18770) in Combination With Lenalidomide and Dexamethasone in Relapsed or Refractory Multiple Myeloma

Completed· Teva logo

Teva·Phase 1/2·NCT01348919·11 enrolled

PAD Combination Therapy Followed by Thal/Dex for Relapsed or Refractory Multiple Myeloma

Unknown status·KKorean Multiple Myeloma Working Party·Phase 2·NCT00319865·47 enrolled

MTD, Safety, and Efficacy of Pomalidomide (CC-4047) Alone or With Low-dose Dexamethasone in Patients With Relapsed and Refractory Multiple Myeloma

Completed· Bristol-Myers Squibb logo

Bristol-Myers Squibb·Phase 1/2·NCT00833833·259 enrolled

Bortezomib and Dexamethasone as Treatment and Maintenance for Multiple Myeloma Relapse

Completed·PPeter MacCallum Cancer Centre, Australia·Phase 2·NCT00335348·101 enrolled

A Study of Venetoclax and ABBV-838 Combination Therapy With Dexamethasone in Participants With Multiple Myeloma Whose Cancer Has Come Back or Had No Response to Recent Cancer Treatment

Withdrawn· AbbVie logo

AbbVie·Phase 1·NCT02951117

Pegylated Liposomal Doxorubicin Hydrochloride, Bortezomib, Cyclophosphamide, and Dexamethasone in Treating Patients With Multiple Myeloma

Terminated·UUniversity of Washington·Phase 1/2·NCT00849251·31 enrolled

A Study of Atezolizumab (Anti-Programmed Death-Ligand 1 [PD-L1] Antibody) Alone or in Combination With an Immunomodulatory Drug and/or Daratumumab in Participants With Multiple Myeloma (MM)

Completed· Roche logo

Roche·Phase 1·NCT02431208·85 enrolled

A Study of Linvo-VR vs DVRd in Transplant-Eligible Adult Participants With Newly Diagnosed Multiple Myeloma (NDMM)

Not yet recruiting· Regeneron logo

Regeneron·Phase 2/3·NCT07428369·1,570 enrolled

Cyclophosphamide, Bortezomib, and Dexamethasone in Treating Patients With Newly Diagnosed Multiple Myeloma

Completed·MMayo Clinic·Phase 2·NCT00609167·63 enrolled

Selinexor, Pomalidomide, and Dexamethasone With or Without Carfilzomib for the Treatment of Patients With Relapsed Refractory Multiple Myeloma, The SCOPE Trial

Active, not recruiting·MMayo Clinic·Phase 1/2·NCT04764942·39 enrolled

MINIALO-VELCADE2005: A Study of Bortezomib (Velcade) Treated Multiple Myeloma Patients Pre and Post Allogeneic Haematopoietic Progenitor Cell Transplant With no Myeloablative Conditioning

Completed·PPETHEMA Foundation·Phase 2·NCT00564200·30 enrolled

Dexamethasone With or Without Thalidomide in Treating Patients With Newly Diagnosed Multiple Myeloma

Completed·NNational Cancer Institute (NCI)·Phase 3·NCT00033332

Leflunomide, Pomalidomide, and Dexamethasone for the Treatment of Relapsed or Refractory Multiple Myeloma

Recruiting·—·Phase 2·NCT04508790·29 enrolled

MLN9708 (Ixazomib) in Combination With Panobinostat and Dexamethasone in Multiple Myeloma

Completed·JJason Valent·Phase 1/2·NCT02057640·16 enrolled

Peripheral Stem Cell Transplantation Plus Combination Chemotherapy in Treating Patients With Multiple Myeloma

Completed·UUniversity of Maryland, Baltimore·Phase 2·NCT00003401

Dexamethasone15 trials

The Effect of Dexamethasone on the Duration of Interscalene Nerve Blocks With Ropivacaine or Bupivacaine

Terminated·TThe Cleveland Clinic·N/A·NCT00801138·218 enrolled

Block Duration After Spinal Block and iv Dexamethasone.

Completed·EEric Albrecht·Phase 4·NCT03527576·50 enrolled

Reduced Fluence Visudyne-Anti-VEGF-Dexamethasone In Combination for AMD Lesions (RADICAL)

Completed·QQLT Inc.·Phase 2·NCT00492284·162 enrolled

Show 12 more trials

Velcade,Thalidomide, and Dexamethasone Versus Velcade and Dexamethasone Versus Velcade, Melphalan, and Prednisone

Completed· Takeda logo

Takeda·Phase 3·NCT00507416·502 enrolled

Epidural Dexamethasone Versus Betamethasone for Treatment of Lumbosacral Radiculalgia

Unknown status·BBasque Health Service·Phase 4·NCT02833116·320 enrolled

Dexamethasone Dose in Low Volume Bupivacaine USG Supraclavicular Block

Unknown status·EEslam Ayman Mohamed Shawki·Phase 4·NCT03043495·40 enrolled

Comparison Between Budesonide and Dexamethasone Treatments for Respiratory Discomfort After Extubation on Children

Unknown status·HHospital Israelita Albert Einstein·N/A·NCT02056379·70 enrolled

rhTPO Combining Dexamethasone Versus High-dose Dexamethasone for Initial Treatment of ITP

Completed·SShandong University·Phase 3·NCT01734044·158 enrolled

Fascia Iliaca Block Supplemented With Perineural Vs Intravenous Dexamethasone

Unknown status·—·Phase 4·NCT04561856·99 enrolled

Effect of Sinufoam-Dexamethasone Mixture on Post Endoscopic Sinus Surgery Outcomes

Unknown status·UUniversity of Calgary·Phase 4·NCT01024075·40 enrolled

Lenalidomide, Rituximab, Gemcitabine, Oxaliplatin and Dexamethasone in Relapse and Refractory DLBCL

Unknown status·TThe First Affiliated Hospital with Nanjing Medical University·Phase 1·NCT03795571·12 enrolled

Administration of Dexamethasone in PONV Prophylaxis in Children Undergoing Adenotomy

Completed·UUniversity Hospital Ostrava·N/A·NCT03398044·200 enrolled

Intracanal Dexamethasone Extrusion and Postoperative Endodontic Pain

Not yet recruiting·UUniversity of Jordan·Phase 1·NCT06894069·80 enrolled

Dexamethasone and Induction of Delivery

Completed·Ssamar sayed el sayed·Phase 1·NCT03658590·102 enrolled

DTPACE Followed by Tandem Transplant With Melphalan (MEL) 200 Versus MEL/Dexamethasone/Thalidomide (DT) Platinol/Adriamycin/Etoposide (PACE) Hybrid and DTPACE Consolidation

Completed·UUniversity of Arkansas·Phase 3·NCT00083915·97 enrolled

Acute Lymphoblastic Leukemia12 trials

Alemtuzumab and Combination Chemotherapy in Treating Patients With Untreated Acute Lymphoblastic Leukemia

Completed·NNational Cancer Institute (NCI)·Phase 1/2·NCT00061945·302 enrolled

Methotrexate, Vincristine, Pegylated L-Asparaginase and Dexamethasone (MOAD) in Acute Lymphoblastic Leukemia (ALL) Salvage

Completed·MM.D. Anderson Cancer Center·Phase 2·NCT00905034·37 enrolled

Temsirolimus, Dexamethasone, Mitoxantrone Hydrochloride, Vincristine Sulfate, and Pegaspargase in Treating Young Patients With Relapsed Acute Lymphoblastic Leukemia or Non-Hodgkin Lymphoma

Completed·NNational Cancer Institute (NCI)·Phase 1·NCT01403415·13 enrolled

Show 9 more trials

Hyper-CVAD With Liposomal Vincristine in Acute Lymphoblastic Leukemia

Completed·MM.D. Anderson Cancer Center·Phase 2·NCT01319981·31 enrolled

Pegaspargase and Combination Chemotherapy in Treating Younger Patients With Newly Diagnosed High-Risk Acute Lymphoblastic Leukemia (Closed to Accrual 4-22-2011)

Completed·CChildren's Oncology Group·Phase 1·NCT00866307·104 enrolled

LAL-Ph-2000: Treatment of Acute Lymphoblastic Leukemia Chromosome Philadelphia Positive

Completed·PPETHEMA Foundation·Phase 4·NCT00526305·100 enrolled

A Study to Investigate LP-118, Ponatinib, Vincristine and Dexamethasone in Relapsed/Refractory Acute Lymphoblastic Leukemia (ALL) or Lymphoblastic Lymphoma (LBL)

Recruiting·UUniversity of Chicago·Phase 1/2·NCT06207123·15 enrolled

Malaysia-Singapore Acute Lymphoblastic Leukemia 2010 Study

Unknown status·NNational University Hospital, Singapore·Phase 4·NCT02894645·500 enrolled

Vincristine, Doxorubicin, And Dexamethasone + Ixazomib in Acute Lymphoblastic Leukemia (ALL), Lymphoblastic Lymphoma Or Mixed Phenotype Acute Leukemia

Terminated·EEhab L Atallah·Phase 1·NCT01887587·5 enrolled

Tagraxofusp and Low-Intensity Chemotherapy for the Treatment of CD123 Positive Relapsed or Refractory Acute Lymphoblastic Leukemia or Lymphoblastic Lymphoma

Terminated·MM.D. Anderson Cancer Center·Phase 1/2·NCT05032183·4 enrolled

Combination Chemotherapy in Treating Young Adult Patients With Acute Lymphoblastic Leukemia

Completed·GGruppo Italiano Malattie EMatologiche dell'Adulto·N/A·NCT01156883·76 enrolled

Bortezomib With Chemotherapy for Relapsed Pediatric Acute Lymphoblastic Leukemia (ALL)

Completed·TTherapeutic Advances in Childhood Leukemia Consortium·Phase 1/2·NCT00440726·31 enrolled

Lymphoma10 trials

Avastin+ GemAOD As First-Line Treatment in NK/T Cell Lymphoma

Unknown status·SSun Yat-sen University·Phase 2·NCT01921790·30 enrolled

Gemcitabine, Cisplatin, and Dexamethasone in Treating Patients With Relapsed or Refractory Hodgkin's Lymphoma

Completed·JJonsson Comprehensive Cancer Center·Phase 2·NCT00090909·1 enrolled

Study Evaluating the Safety and Efficacy of KTE-C19 in Adult Participants With Refractory Aggressive Non-Hodgkin Lymphoma

Completed· Gilead logo

Gilead·Phase 1/2·NCT02348216·307 enrolled

Show 7 more trials

Combination Chemotherapy in Hodgkin's Disease or Non-Hodgkin's Lymphoma Not Responding to Previous Treatment

Completed·NNCIC Clinical Trials Group·Phase 2·NCT00014209·77 enrolled

Linperlisib Combined With Camrelizumab and Pegaspargase in Advanced or Relapsed/Refractory NK/T-cell Lymphoma

Recruiting·—·Phase 1/2·NCT06376721·43 enrolled

Study Comparing Inotuzumab Ozogamicin In Combination With Rituximab Versus Defined Investigator's Choice In Follicular Non-Hodgkin's Lymphoma (NHL)

Terminated· Pfizer logo

Pfizer·Phase 3·NCT00562965·29 enrolled

Methotrexate, Cyclophosphamide, and Etoposide Phosphate Given With Osmotic Blood-Brain Barrier Disruption Plus Dexamethasone and Cytarabine in Treating Patients With Primary CNS Lymphoma

Completed·OOHSU Knight Cancer Institute·Phase 2·NCT00074178·22 enrolled

Phase I Study of Romidepsin, Gemcitabine, Oxaliplatin, and Dexamethasone in Patients With Relapsed/Refractory Aggressive Lymphomas

Completed·WWashington University School of Medicine·Phase 1·NCT02181218·24 enrolled

Chemotherapy Before Autologous Stem Cell Transplantation +/- Rituximab in Relapsed or Refractory Aggressive Non-Hodgkin's Lymphoma

Completed·NNCIC Clinical Trials Group·Phase 3·NCT00078949·849 enrolled

BrECADD Therapy in Stage 2 B-IV Hodgkin Lymphoma

Recruiting·UUniversity of Miami·Phase 2·NCT07002216·48 enrolled

Immune Thrombocytopenia5 trials

Rituximab and Dexamethasone Followed by Mycophenolate Mofetil or Placebo in Patients With Immune Thrombocytopenia

Withdrawn·WWeill Medical College of Cornell University·Phase 3·NCT02649504

Low-dose Baricitinib Plus High-dose Dexamethasone for Patients With Newly Diagnosed Immune Thrombocytopenia

Unknown status·PPeking University People's Hospital·Phase 2·NCT05932524·132 enrolled

Romiplostim Plus Dexamethasone vs Dexamethasone in Patients With Newly Diagnosed Primary Immune Thrombocytopenia

Active, not recruiting·FFundación Pública Andaluza para la gestión de la Investigación en Sevilla·Phase 3·NCT05325593·129 enrolled

Show 2 more trials

Connection Between Vitamin D Level and the Efficacy of Dexamethasone in Immune Thrombocytopenia

Unknown status·SShandong University··NCT04320225·60 enrolled

High-dose Dexamethasone Versus Conventional Dose Prednisone for Initial Treatment of Primary Immune Thrombocytopenia (ITP)

Completed·SShandong University·Phase 4·NCT01356511·261 enrolled

90 more indications

Mantle Cell Lymphoma4 trials

EDOCH Alternating With DHAP for New Diagnosed Younger MCL

Completed·IInstitute of Hematology & Blood Diseases Hospital, China·Phase 4·NCT02858804·55 enrolled

Bortezomib, Rituximab and Dexamethasone (BORID) for Relapsed/Refractory Mantle Cell Lymphoma

Unknown status·MMedical University of Vienna·Phase 2·NCT00261612·16 enrolled

S0213 Chemotherapy Plus Rituximab in Treating Patients With Mantle Cell Lymphoma

Completed·SSWOG Cancer Research Network·Phase 2·NCT00041132·56 enrolled

Show 1 more trial

Treatment of Mantle Cell Lymphoma at Diagnosis for Patients Under 65 Years

Completed·FFrench Innovative Leukemia Organisation·Phase 2·NCT00285389·39 enrolled

Primary Systemic Amyloidosis4 trials

Melphalan, Lenalidomide, and Dexamethasone in Treating Patients With Primary Systemic Amyloidosis

Completed·—·Phase 2·NCT00679367·16 enrolled

Low-Dose Melphalan and Dexamethasone Compared With High-Dose Melphalan Followed By Autologous Stem Cell Transplant in Treating Patients With Primary Systemic Amyloidosis

Completed·MMayo Clinic·Phase 3·NCT00477971·89 enrolled

Melphalan, Thalidomide, and Dexamethasone in Treating Patients With Newly Diagnosed, Previously Untreated Primary Systemic Amyloidosis

Completed·MMemorial Sloan Kettering Cancer Center·Phase 2·NCT00089167

Show 1 more trial

S9628 Dexamethasone Plus Interferon Alfa in Treating Patients With Primary Systemic Amyloidosis

Completed·SSWOG Cancer Research Network·Phase 2·NCT00002849·93 enrolled

Efficacy and Safety3 trials

Efficacy and Safety of Low-dose Chemotherapy Plus Immuno-targeted Drugs in Newly Diagnosed Adult Ph- B-ALL

Recruiting·IInstitute of Hematology & Blood Diseases Hospital, China·Phase 2·NCT06387121·53 enrolled

The Efficacy and Safety of Palonosetron in Preventing the Gastrointestinal Reactions Induced by 3-day Highly Emetogenic Chemotherapy

Completed· Jiangsu Simcere Pharmaceutical Co., Ltd. logo

Jiangsu Simcere Pharmaceutical Co., Ltd.·Phase 2·NCT01909856·92 enrolled

An Exploratory Study on Efficacy and Safety of Fosaprepitant and Palonosetron Hydrochloride for Injection in Preventing CINV From Multi-Agent HEC

Not yet recruiting·SShanghai 6th People's Hospital·Phase 4·NCT07482891·200 enrolled

Chemotherapy3 trials

A Pilot Study of Decitabine and Vorinostat With Chemotherapy for Relapsed ALL

Terminated·TTherapeutic Advances in Childhood Leukemia Consortium·Phase 1/2·NCT01483690·23 enrolled

Palonosetron in Sarcoma Patients Receiving Chemotherapy With Adriamycin and Ifosfamide (AI)

Completed·MM.D. Anderson Cancer Center·N/A·NCT00410488·51 enrolled

Aprepitant Triple Therapy for the Prevention of CINV in Nondrinking and Young Women Who Received Moderately Emetogenic Chemotherapy

Completed·SSun Yat-sen University·Phase 3·NCT03674294·248 enrolled

Steroid3 trials

Peri-Operative Steroid Management in Patients

Completed·WWashington University School of Medicine·N/A·NCT02084134·43 enrolled

Particulate vs. Non-Particulate Steroid for Sacroiliac Joint Injection

Recruiting·UUniversity of New Mexico·Phase 4·NCT06268704·230 enrolled

Distal Radius Steroid

Terminated·IIndiana Hand to Shoulder Center·Phase 1·NCT05655130·30 enrolled

Pneumonia3 trials

Santeon-CAP; Dexamethasone in Community-acquired Pneumonia

Terminated·SSt. Antonius Hospital·Phase 4·NCT01743755·413 enrolled

Efficacy and Safety of Siltuximab vs. Corticosteroids in Hospitalized Patients With COVID-19 Pneumonia

Completed·JJudit Pich Martínez·Phase 2·NCT04329650·163 enrolled

Dexamethasone Infusion in Community-acquired Pneumonia

Completed·SSt. Antonius Hospital·N/A·NCT00471640·300 enrolled

Nausea and vomiting2 trials

Dexamethasone for the Prevention of Post-operative Nausea and Vomiting in Patients Undergoing Cesarean Sections

Completed·WWeill Medical College of Cornell University·Phase 4·NCT01734161·122 enrolled

Efficacy of Prevention for Postoperative Nausea and Vomiting After Intrathecal Morphine in Cesarean Section

Unknown status·MMahidol University·N/A·NCT00892996·120 enrolled

Adductor Canal Block2 trials

Neostigmine and Dexamethasone in Adductor Canal Block

Completed·—·N/A·NCT04565301·90 enrolled

Dexamethasone Versus Demedetomidine Addition for Adductor Canal Block

Completed·—·N/A·NCT06527976·90 enrolled

COVID-192 trials

Comparison of Tocilizumab Plus Dexamethasone vs. Dexamethasone for Patients With Covid-19

Completed·AAssistance Publique - Hôpitaux de Paris·Phase 2·NCT04476979·453 enrolled

Glucocorticoid Therapy in Coronavirus Disease COVID-19 Patients

Terminated·FFundación Instituto de Estudios de Ciencias de la Salud de Castilla y León·Phase 4·NCT04780581·128 enrolled

Cesarean Delivery2 trials

Dexamethasone for Post-cesarean Delivery Pain

Completed·—·Phase 4·NCT01812057·53 enrolled

Dexamethasone Administered Via the Epidural Catheter as an Adjunct in Patients Undergoing Cesarean Delivery

Withdrawn·HHenry Ford Health System·Phase 4·NCT03877549

Spinal Anesthesia2 trials

Intravenous Dexamethasone for Prolonging Sensory Block in Spinal Anesthesia

Completed·TTunis University·N/A·NCT07088432·120 enrolled

Prophylactic Paracetamol or Dexamethasone for Post-spinal Anesthesia Shivering

Completed·—·Phase 4·NCT03679065·300 enrolled

Leukemia2 trials

Combination Chemotherapy in Treating Children With Relapsed Acute Lymphocytic Leukemia

Unknown status·GGrupo Argentino de Tratamiento de la Leucemia Aguda·Phase 2/3·NCT00002499

Treatment Protocol of the NHL-BFM and the NOPHO Study Groups for Mature Aggressive B-cell Lymphoma and Leukemia in Children and Adolescents

Active, not recruiting·UUniversity Hospital Muenster·Phase 3·NCT03206671·650 enrolled

Knee Arthroplasty1 trial

Dexamethasone Vs. Dexmedetomidine for ESPB in Pain Management After Knee Arthroplasty

Recruiting·PPoznan University of Medical Sciences·Phase 4·NCT06470100·90 enrolled

Hypospadias1 trial

Does the Single Use of Intravenous Dexamethasone Enhance Analgesic Quality of Pudendal Analgesia in Children Undergoing Hypospadias Surgery?

Completed·YYonsei University·N/A·NCT04836962·46 enrolled

Cellulitis1 trial

Use of Corticosteroids in Children With Cellulitis

Terminated·HHospital General de Niños Pedro de Elizalde·N/A·NCT02087527·19 enrolled

Inguinal hernia1 trial

Dexamethasone Versus Placebo in Optimizing the Postoperative Period After Laparoscopic Inguinal Hernia Repair

Completed·MMette Astrup Madsen·Phase 3·NCT01170780·80 enrolled

Dysphagia1 trial

Effect of Intravenous Corticosteroid Injections on Dysphagia After Cervical Spine Surgery

Terminated·NNYU Langone Health·Phase 3·NCT02266797·4 enrolled

Intravitreal Injections1 trial

Extension Study to Compare Long-term Efficacy and Safety of Ranibizumab Intravitreal Injections Versus Dexamethasone Intravitreal Implant in Patients With RVO

Completed· Novartis logo

Novartis·Phase 4·NCT01580020·175 enrolled

Labor Analgesia1 trial

Intrathecal Dexamethasone and Labor Analgesia

Completed·Aahmed elsakka·Phase 2·NCT02588417·80 enrolled

ACL Reconstruction1 trial

A Novel Analgesia Technique for ACL Reconstruction

Completed·HHospital for Special Surgery, New York·Phase 4·NCT03292926·78 enrolled

Maintenance Therapy1 trial

Maintenance Therapy With Subcutaneous Bortezomib

Completed·EEuropean Myeloma Network B.V.·Phase 2·NCT01913730·63 enrolled

Arthroscopic Shoulder Surgery1 trial

Extension of Analgesia by Combined Injection of Dexamethasone and Dexmedetomidine After Arthroscopic Shoulder Surgery

Completed·GGCS Ramsay Santé pour l'Enseignement et la Recherche·Phase 4·NCT04394481·122 enrolled

Elderly Patients1 trial

Melflufen for Elderly Patients With Relapsed Myeloma

Withdrawn·FFondazione EMN Italy Onlus·Phase 2·NCT06682637

Total Hip Arthroplasty1 trial

Effect of Preoperative Intravenous Dexamethasone on Postoperative Pain After Primary Total Hip Arthroplasty

Unknown status·—·Phase 4·NCT03542617·57 enrolled

Cesarean Section1 trial

Role of Dexamethasone in Transversus Abdominis Plane Block After Cesarean Section

Completed·—·N/A·NCT03767920·120 enrolled

Effectiveness1 trial

Safety and Effectiveness of Ozurdex Steroid Implants for DME After Vitrectomy Surgery

Terminated·LLahey Clinic·N/A·NCT01788475·3 enrolled

Non-squamous NSCLC1 trial

Pembrolizumab Plus Bevacizumab and Chemotherapy for Non-Squamous NSCLC Patients

Active, not recruiting·SShanghai Chest Hospital·Phase 2·NCT05751187·54 enrolled

Acute Kidney Injury1 trial

The Effect of High Single Dose of Dexamethasone in Prevention of Post-operative Acute Kidney Injury in Cardiac Surgeries Requiring Cardiopulmonary Bypass

Unknown status·—·Phase 1·NCT06783634·60 enrolled

Hypotension1 trial

Efficacy of Dexamethasone in Attenuation of Postinduction Hypotension in Geriatric Patients Undergoing General Anesthesia

Completed·—·Phase 4·NCT04908592·100 enrolled

Anaplastic Large Cell Lymphoma1 trial

Combination Chemotherapy Followed By Stem Cell Transplant in Treating Young Patients With Progressive or Relapsed Anaplastic Large Cell Lymphoma

Unknown status·EEuropean Inter-group Cooperation on Childhood and Adolescent Non Hodgkin Lymphoma·N/A·NCT00317408·96 enrolled

Radius Fracture1 trial

Perioperative Glucocorticoid Administration in the Treatment of Adult Distal Radius Fractures

Recruiting·CC. Liam Dwyer·Phase 4·NCT03898154·200 enrolled

Corticosteroids1 trial

Corticosteroids as Additive in Temporomandibular Joint (TMJ) Arthrocentesis

Unknown status·UUniversity Medical Center Groningen·Phase 4·NCT01275014·28 enrolled

Lung Inflammation1 trial

Validation of a Lung Inflammation Model in Healthy Volunteers by Radiological Tools and Glucocorticoid Treatment

Completed·MMedical University of Vienna·N/A·NCT01714427·36 enrolled

Function1 trial

Neural Compensation, Visual Function and Visual Quality After Monofocal or Multifocal Intraocular Lens Implantation

Unknown status·SSun Yat-sen University·N/A·NCT02644720·50 enrolled

Intravenous Administration1 trial

Comparative Study Between the Prophylactic Intravenous Administrations of Acetaminophen vs Dexamethasone vs Pethidine Regarding the Incidence of Shivering Induced by Single Shot Spinal Anesthesia in the Orthopedic Surgeries of the Lower Limbs

Completed·—·Phase 4·NCT05284409·130 enrolled

Asthma1 trial

Comparison of Oral Dexamethasone Doses in Asthma Exacerbation

Completed·RRady Children's Hospital, San Diego·N/A·NCT00942201·125 enrolled

Hematological Malignancies1 trial

Phase 1/2 Dose Escalation and Efficacy Study of Anti-CD38 Monoclonal Antibody in Patients With Selected CD38+ Hematological Malignancies

Completed· Sanofi logo

Sanofi·Phase 1/2·NCT01084252·351 enrolled

Acute Myeloid Leukemia1 trial

Gene Expression During Chemotherapy in Patients With Newly Diagnosed Acute Myeloid Leukemia Treated With Choline Magnesium Trisalicylate

Terminated·RRutgers, The State University of New Jersey·Phase 1·NCT00156299·15 enrolled

Relapsed/Refractory1 trial

Study of the Safety, Tolerability and Efficacy of KPT-8602 in Participants With Relapsed/Refractory Cancer Indications

Completed·KKaryopharm Therapeutics Inc·Phase 1/2·NCT02649790·277 enrolled

Encephalopathy1 trial

Eclampsia and Posterior Reversible Encephalopathy Syndrome (PRES):

Terminated·UUniversity of Mississippi Medical Center·N/A·NCT02027272·1 enrolled

Refractory1 trial

A Phase III Study of Eque-cel in Subjects With Len-refractory RRMM (FUMANBA-03)

Recruiting·NNanjing IASO Biotechnology Co., Ltd.·Phase 3·NCT06464991·240 enrolled

Aspirin1 trial

Linezolid, Aspirin and Enhanced Dose Rifampicin in HIV-TBM

Completed·UUniversity of Cape Town·Phase 2·NCT03927313·52 enrolled

Pediatric ALL1 trial

ABT-751 With Chemotherapy for Relapsed Pediatric ALL

Terminated·TTherapeutic Advances in Childhood Leukemia Consortium·Phase 1/2·NCT00439296·9 enrolled

Nausea1 trial

Nausea and Pain Prophylaxis During Thyroid Surgery

Completed·SSykehuset Telemark·N/A·NCT00569920·120 enrolled

Liver Cancer1 trial

Floxuridine and Dexamethasone as a Hepatic Arterial Infusion and Bevacizumab in Treating Patients With Primary Liver Cancer That Cannot be Removed by Surgery

Completed·MMemorial Sloan Kettering Cancer Center·Phase 2·NCT00410956·22 enrolled

Thyroid Surgery1 trial

Ultrasound Guided Intermediate Cervical Plexus Block in Thyroid Surgery

Completed·—·N/A·NCT03731468·60 enrolled

Gastric Adenocarcinoma1 trial

Study of Hyperthermic Intraperitoneal Chemoperfusion (HIPEC) in Patients With Gastric Adenocarcinoma and Carcinomatosis or Positive Cytology

Completed·MM.D. Anderson Cancer Center·Phase 1·NCT03330028·29 enrolled

Cataract1 trial

Phase 3 Study Evaluating Safety and Efficacy of OTX-DP for Treatment of Ocular Inflammation and Pain After Cataract Surgery

Completed·OOcular Therapeutix, Inc.·Phase 3·NCT02034019·247 enrolled

Analgesic Efficacy1 trial

The Analgesic Efficacy of Two Bupivacaine Concentrations for Combined Ilioinguinal and Iliohypogastric Nerve Block in Postherniorrhaphy Pain

Unknown status·TTanta University·Phase 1·NCT05687981·90 enrolled

Meningitis1 trial

Adjunctive Corticosteroids for Tuberculous Meningitis in HIV-infected Adults (The ACT HIV Trial)

Completed·OOxford University Clinical Research Unit, Vietnam·Phase 3·NCT03092817·520 enrolled

Steroid Injection1 trial

An Evaluation of Blood Glucose Levels and Insulin Requirement After Subacromial Corticosteroid Injection in Insulin Dependent Diabetics

Withdrawn·UUniversity of Pittsburgh·N/A·NCT03328975

Randomized1 trial

A Multicenter Randomized Open-label Study of Oseltamivir Combined With HD-DEX Versus HD-DEX in the Management of ITP

Completed·SShandong University·Phase 2·NCT01965626·96 enrolled

Wound Healing1 trial

The Use of Bevacizumab as a Modulator of Wound Healing Following Trabeculectomy Surgery

Completed·MMoorfields Eye Hospital NHS Foundation Trust·Phase 3·NCT02767219·6 enrolled

Chronic Graft Versus Host Disease1 trial

Clinical Trial With Clobetasol and Dexamethasone for Topical Treatment of Oral Lesions of Chronic Graft-versus-host Disease

Completed·GGrupo de Estudos Multicentricos em Onco-Hematologia·Phase 3·NCT01699412·28 enrolled

Relapsed or Refractory Hematologic Malignancies1 trial

Bendamustine Hydrochloride, Clofarabine, and Etoposide in Treating Younger Patients With Relapsed or Refractory Hematologic Malignancies

Completed·SSt. Jude Children's Research Hospital·Phase 1·NCT01900509·16 enrolled

Total Knee Arthroplasty1 trial

Dexamethasone and Pain Following Total Knee Arthroplasty

Completed·—·Phase 4·NCT02271698·45 enrolled

Video-Assisted Thoracoscopic Surgery1 trial

High Dose Dexamethasone to Reduce Postoperative Pain After Video-Assisted Thoracoscopic Surgery Lobectomy /Segmentectomy

Recruiting·RRigshospitalet, Denmark·Phase 2/3·NCT07213375·80 enrolled

Metastatic Urothelial Cancer1 trial

Iressa and Taxotere Study in Patients With Metastatic Urothelial Cancer

Terminated·MM.D. Anderson Cancer Center·Phase 2·NCT00479089·50 enrolled

Cryptococcal Meningitis1 trial

Dexamethasone in Cryptococcal Meningitis

Completed·NNational Institute of Allergy and Infectious Diseases (NIAID)·Phase 2·NCT00000776·36 enrolled

Amyloidosis1 trial

Lenalidomide in Combination With Melphalan and Dexamethasone in Newly-diagnosed Light-chain (AL)-Amyloidosis

Completed·NNantes University Hospital·Phase 1/2·NCT00621400·27 enrolled

Complication1 trial

The Effect of Perioperative DEXamethasone on Postoperative Complications After PANcreaticoduodenectomy

Completed·RRuijin Hospital·Phase 4·NCT05567094·300 enrolled

AL amyloidosis1 trial

Ixazomib Maintenance Study in Patients With AL Amyloidosis

Active, not recruiting·MMemorial Sloan Kettering Cancer Center·Phase 2·NCT03618537·17 enrolled

Post Operative Sore Throat1 trial

Combined Effect of Dexamethasone and Paracetamol for Postoperative Sore Throat

Unknown status·SSeoul National University Hospital·N/A·NCT02252419·242 enrolled

Infusion1 trial

A PK, Safety and Tolerability Study of Peripheral and Central Infusion of Melflufen in RRMM Patients

Terminated·OOncopeptides AB·Phase 2·NCT04412707·27 enrolled

Interscalene Brachial Plexus Block1 trial

Comparison Between Perineural and Systemic Effect of Dexamethasone for Interscalene Brachial Plexus Block.

Unknown status·HHillel Yaffe Medical Center·N/A·NCT02190760·90 enrolled

Supraclavicular Brachial Plexus Block1 trial

Peri-neural Dexmedetomidine Versus Dexamethasone for Supraaclavicular Block Adjuvant to Bupivacaine Supraclavicular Brachial Plexus Block

Completed·—·N/A·NCT04694105·42 enrolled

Newly Diagnosed1 trial

First-line Dasatinib Plus Conventional Chemotherapy in Adults With Newly Diagnosed Ph-Positive ALL

Completed·TThe Catholic University of Korea·Phase 2·NCT01004497·51 enrolled

Urinary Tract Infection1 trial

Corticosteroids for Children With Febrile Urinary Tract Infections

Completed·NNader Shaikh·Phase 3·NCT01391793·546 enrolled

Sepsis1 trial

Safety and Efficacy of Early Administration of Dexamethasone in High-risk Sepsis

Recruiting·—·Phase 1/2·NCT05136560·102 enrolled

Bronchopulmonary Dysplasia1 trial

Phase III Randomized, Double-Blind Study of Dexamethasone Vs Dexamethasone/Methylprednisolone Vs Placebo for Bronchopulmonary Dysplasia

Completed·NNational Center for Research Resources (NCRR)·Phase 3·NCT00004785·54 enrolled

Croup1 trial

Community Care for Croup (RCT)

Completed·WWashington University School of Medicine·Phase 4·NCT01042145·87 enrolled

Stem Cell Transplant1 trial

Pre-transplant Immunosuppression and Donor Stem Cell Transplant for the Treatment of Severe Hemoglobinopathies

Withdrawn·MM.D. Anderson Cancer Center·Phase 1·NCT04776850

Endometrial Carcinoma1 trial

Phase 2 Study of ET-743 (Trabectedin) in Patients With Persistent or Recurrent Endometrial Carcinoma

Completed· Johnson & Johnson Pharmaceutical Research & Development, L.L.C. logo

Johnson & Johnson Pharmaceutical Research & Development, L.L.C.·Phase 2·NCT00050440·50 enrolled

Cognition1 trial

Effects of Steroid Tapering on Functional Capacity and Neurocognition

Withdrawn·—·N/A·NCT01169415

Third Molar Surgery1 trial

Evaluation of Two Pharmacological Protocols for Pre-emptive Analgesia in Impacted Third Molar Surgery

Completed·FFederal University of the Valleys of Jequitinhonha and Mucuri·N/A·NCT02665533·18 enrolled

Posterior Uveitis1 trial

Dexamethasone Intravitreal Implant (Ozurdex®) for Recurrent Vogt-Koyanagi-Harada (VKH) Disease Posterior Uveitis

Completed·—··NCT03971279·16 enrolled

Post-cesarean Pain1 trial

Postoperative Dexamethasone on Post-Cesarean Pain

Completed·YYale University·Phase 4·NCT04067609·24 enrolled

Myelodysplastic Syndromes1 trial

E7070, Idarubicin and Cytarabine in Relapsed AML and High-Risk Myelodysplastic Syndromes

Completed·MM.D. Anderson Cancer Center·Phase 2·NCT01692197·43 enrolled

Relapsed or Refractory1 trial

Efficacy and Safety of R-HAD Alone or in Combination With Bortezomib in Patients With Relapsed or Refractory MCL

Unknown status·PProf. Dr. M. Dreyling (co-chairman)·Phase 3·NCT01449344·128 enrolled

Radiculopathy1 trial

Cervical Retrolaminar Block Versus Cervical Epidural Injection for Cervical Radiculopathy

Completed·IIstanbul Medeniyet University·N/A·NCT07275320·70 enrolled

Unresectable Solid Tumor1 trial

Calcitriol, Ketoconazole, and Dexamethasone in Treating Patients With Metastatic or Unresectable Solid Tumors

Completed·RRoswell Park Cancer Institute·Phase 1·NCT00238225·15 enrolled

Hip Arthroplasty1 trial

Dexamethasone vs. Dexmedetomidine for ESPB in Pain Management After Hip Arthroplasty

Recruiting·PPoznan University of Medical Sciences·Phase 4·NCT06233604·30 enrolled

Laparoscopic Cholecystectomy1 trial

Dexamethasone Improves Postoperative Symptoms After Laparoscopic Cholecystectomy

Completed·IInstituto Mexicano del Seguro Social·Phase 3·NCT01030614·210 enrolled

Colorectal Cancer1 trial

Adjuvant Hepatic Arterial Infusion and Combination Chemotherapy in Treating Patients With Resectable Hepatic Metastases From Colorectal Cancer

Completed·MMemorial Sloan Kettering Cancer Center·Phase 1·NCT00059930·38 enrolled

Treatment1 trial

Early Patient Access Treatment Use Protocol CA204-220

No longer available· Bristol-Myers Squibb logo

Bristol-Myers Squibb··NCT02856438

Hypersensitivity1 trial

Conventional Prophylactic Oral Dexamethasone vs Short-course IV Dexamethasone in Paclitaxel Hypersensitivity

Completed·LLoma Linda University·Phase 3·NCT03598426·90 enrolled

Functional Endoscopic Sinus Surgery1 trial

Regional Anesthesia to Reduce Opioid Use Following Functional Endoscopic Sinus Surgery

Completed·UUniversity of Alabama at Birmingham·Phase 4·NCT03757715·46 enrolled

Dexmedetomidine1 trial

Dexamethasone vs Dexmedetomidine vs Combination as Adjuvants to Popliteal Sciatic Nerve Block in Children

Recruiting·PPoznan University of Medical Sciences·N/A·NCT07289620·120 enrolled

TED1 trial

Comparison of Pom and Dex in Subjects With RRMM Previously Treated With Len and a PI Dara/Pom/Dex vs Pom/Dex

Completed·SStichting European Myeloma Network·Phase 3·NCT03180736·304 enrolled

Unspecified1 trial

GMMG-HD10 / DSMM-XX / 64007957MMY2003, MajesTEC-5

Recruiting·UUniversity of Heidelberg Medical Center·Phase 2·NCT05695508·160 enrolled

Regulatory

FDA Approval Timeline[5]

Jan 1, 1982

DECADRON

NDA NDA012376

Jan 1, 1982

HEXADROL

NDA NDA012674

Jan 1, 1982

DECADERM

NDA NDA013538

Jan 1, 1982

DECADRON

NDA NDA012071

Jan 1, 1982

DECADRON-LA

NDA NDA016675

Jan 1, 1982

HEXADROL

NDA NDA014694

Jan 1, 1982

DECADRON

NDA NDA011977

Jan 1, 1982

DECADRON

NDA NDA011984

Jan 1, 1982

MAXIDEX

NDA NDA013422

Jan 1, 1982

DECADRON

NDA NDA011664

Jan 1, 1982

DEXACORT

NDA NDA013413

Jan 1, 1982

HEXADROL

NDA NDA012675

Jan 1, 1982

DEXACORT

NDA NDA014242

Jan 1, 1982

DECASPRAY

NDA NDA012731

Jan 1, 1982

DECADRON

NDA NDA011983

Jun 17, 2009

OZURDEX

NDA NDA022315

Feb 9, 2018

DEXYCU KIT

NDA NDA208912

Nov 30, 2018

DEXTENZA

NDA NDA208742

Oct 3, 2019

HEMADY

NDA NDA211379

Sources

References

[1]
ClinicalTrials.gov — 2348 trial records for dexamethasone. U.S. National Library of Medicine, National Institutes of Health.
[2]
MedlinePlus Drug Information — Decadron drug information. U.S. National Library of Medicine, National Institutes of Health.
[3]
ChEMBL — dexamethasone compound record. European Bioinformatics Institute (EMBL-EBI).
[4]
Open Targets Platform — Drug–disease associations for dexamethasone. EMBL-EBI & Wellcome Sanger Institute.
[5]
OpenFDA — FDA approval records (NDA NDA211379). U.S. Food & Drug Administration.
[6]
FDA Orange Book — Patent and exclusivity data for Decadron. U.S. Food & Drug Administration.
[7]
SEC EDGAR — Aspen Global Incorporated company filings. U.S. Securities and Exchange Commission.

Details

Drug Info

Quick Facts

Mechanism of Action: Glucocorticoid Receptor Agonist[3]
Modality: Small molecule[3]
Highest Phase: Approved[1]
Company: AAspen Global Incorporated

Patent Landscape[6]

Patent Cliff

Feb 12, 2030

Earliest patent expiration — generic entry possible after this date

Patent #Expires

8563027Feb 12, 2030

8409606May 14, 2030

10799642May 11, 2032

10028965May 23, 2034

10159683May 23, 2034

7 more patents

10022502Jun 22, 2034

12150896Oct 7, 2036

11458041Nov 16, 2037

11304961Dec 18, 2037

10537585Dec 18, 2037

11097061Jun 23, 2039

12144889Apr 26, 2041