VivoSeq
177

Pipeline Programs

51

Active Trials

82

Companies Involved

Cirrhosis is a highly competitive landscape with 177 programs across 82 companies. The most active players are Alentis Therapeutics AG, Amgen, Fresenius. 40 therapies are approved with 30 more in late-stage development.

Pipeline Metrics

Competitive Density

80/100

Pipeline Velocity

37/100

Mech. Concentration

4/100

Completion Rate

81/100

Attrition Rate

9/100

Competitive Landscape

Bubble size = clinical trials

Approved
Phase 3
Phase 2
Phase 1
Preclinical

Programs by Phase

Modality Breakdown

87%

Small molecule

195 of 223 classified programs — the dominant modality here.

13%ALL OTHERSCell therapy178%Peptide63%Protein / enzyme42%Vaccine1<1%

Small molecule leads; the ring shows all 223 classified programs, each share of the total. Modality classified for 98% of 253 pipeline programs.

Trial Status

265

clinical trials

Completed115 · 43%
Unknown status72 · 27%
Recruiting30 · 11%
Terminated18 · 7%
Not yet recruiting15 · 6%
Withdrawn7 · 3%
Other8 · 3%

Trial Activity

265 trials

Statin and Beta Blocker Use in Patients With Decompensated Cirrhosis
Recruiting··Phase 2·NCT06764966·50 enrolled
Empagliflozin in Patients With Cirrhosis and Ascites
Recruiting·YYale University·Phase 2·NCT05726032·20 enrolled
Coagulation in Cirrhosis
Recruiting·MMedical University of Vienna·Phase 4·NCT05667805·400 enrolled
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Data sources: ClinicalTrials.gov (NIH) · OpenFDA (FDA) · ChEMBL (EMBL-EBI) · Open Targets (EBI/Sanger) · MedlinePlus (NIH) · PubMed (NIH) · SEC EDGAR (SEC)