Crestor

(rosuvastatin)

ApprovedSmall molecule

Rosuvastatin is used to lower cholesterol and triglycerides in the blood, which helps reduce the risk of heart disease and stroke.[2] Crestor is currently approved and in use across 77 indications[4].[1]

Crestor is one of 1139 small molecule programs targeting Acute Coronary Syndrome. It is currently in Approved.

Indications

537

Total Trials

Active Trials

1,138

Competitors

FDA Applications

NDA/BLA/ANDA regulatory filings

Patents

Pipeline

Status by Indication[4][1]

Indication

Acute Coronary SyndromeUnknown status

Heart DiseaseCompleted

StatinUnknown status

StatinsRecruiting

MaleNot yet recruiting

Severe Pre-EclampsiaApproved

Anemia (phenotype)Approved

Hepatitis C Virus InfectionApproved

Dilated CardiomyopathyApproved

Systemic SclerodermaApproved

Acute Coronary SyndromeApproved

Unknown status

Heart DiseaseApproved

Completed

StatinApproved

Unknown status

StatinsApproved

Recruiting

MalePhase 1

Not yet recruiting

Severe Pre-EclampsiaApproved

Approved

Anemia (phenotype)Approved

Approved

Hepatitis C Virus InfectionApproved

Approved

Dilated CardiomyopathyApproved

Approved

Systemic SclerodermaApproved

Approved

Showing 10 of 76 indications

Competition

Competitive Landscape

314 competitors in Prostate Cancer

#DrugCompanyPhaseTrials

Lupron

EEastern Cooperative Oncology Group

Phase 3

53 2

Zoladex

TTerSera Therapeutics LLC

Phase 3

35 3

Crestor

AstraZeneca

Approved

2 4

Androgen Deprivation Therapy

Johnson & Johnson

Phase 3

48 5

Talzenna

Pfizer

Phase 3

7 6

Acetylsalicylic Acid

Bayer

Phase 3

2 7

PSMA-1007

AABX advanced biochemical compounds GmbH

Phase 3

3 8

INR101

YYunhe Pharmaceutical (Tianjin) Co., Ltd

Phase 3

3 9

Trexall

Jazz Pharmaceuticals

Preclinical

—10

Jatenzo

GGrupo Espanol de Tumores Neuroendocrinos

Preclinical

Ranked by pipeline maturity and clinical activity. Current drug highlighted in teal.

Timeline

Expected Milestones

Q2 2027

Post-ApprovalRecruiting

Coronary Atherosclerosis

NCT05850091

Q3 2027

Phase 3Recruiting

Diabetes Mellitus

NCT04602754

Q2 2028

Phase 3Recruiting

Venous Thromboembolism

NCT04319627

Clinical

Trials by Indication[1]

Statin33 trials

A Study to Compare the Pharmacokinetics and Safety of a Fixed Dose Combination of Fimasartan/Amlodipine/Rosuvastatin

Completed· Boryung Pharmaceutical Co., Ltd logo

Boryung Pharmaceutical Co., Ltd·Phase 1·NCT02569814·100 enrolled

Direct Statin Comparison of LDL-C Values: an Evaluation of Rosuvastatin Therapy

Completed· AstraZeneca logo

AstraZeneca·Phase 3·NCT00239330·824 enrolled

Is Augmentation of PORH by Rosuvastatin Adenosine-receptor Mediated?

Completed·RRadboud University Medical Center·Phase 4·NCT00851175·8 enrolled

Show 30 more trials

A Study to Assess the Safety, Tolerability, Pharmacokinetics, and Pharmacodynamics of AZD4144 as Well as the Impact of AZD4144 on the Pharmacokinetics of Rosuvastatin and Furosemide in Healthy Participants

Completed· AstraZeneca logo

AstraZeneca·Phase 1·NCT06491550·91 enrolled

Study in Taiwanese Subjects Identified as CYP2C19 Poor and Extensive Metabolizers Receiving Rosuvastatin

Completed· AstraZeneca logo

AstraZeneca·Phase 1·NCT00766025·50 enrolled

A Study Measuring Effects on Intima Media Thickness: An Evaluation of Rosuvastatin 40 mg (METEOR)

Completed· AstraZeneca logo

AstraZeneca·Phase 3·NCT00225589·840 enrolled

A Phase I, Open-label, Crossover Study Comparing the Relative Bioavailability of a Fixed-Dose Combination of Laroprovstat/Rosuvastatin vs Their Single Therapy Products in Healthy Adults

Not yet recruiting· AstraZeneca logo

AstraZeneca·Phase 1·NCT07316608·44 enrolled

The Role of Rosuvastatin on Vascular Involvement in Behçet's Disease

Completed·UUniversity of Alexandria·N/A·NCT04328064·56 enrolled

Statin and Atheroma Vulnerability Evaluation

Completed·SSeung-Jung Park·Phase 4·NCT00997880·312 enrolled

Rosuvastatin ORBITAL Germany

Completed· AstraZeneca logo

AstraZeneca·Phase 3·NCT00379249·8,000 enrolled

A Study in Healthy Male Subjects to Investigate Whether Administration of ACT-541468 Can Affect the Fate in the Body (Amount and Time of Presence in the Blood) of Rosuvastatin

Completed· Idorsia Pharmaceuticals Ltd. logo

Idorsia Pharmaceuticals Ltd.·Phase 1·NCT03339752·20 enrolled

Comparison of the Bioavailability of Fenofibric Acid and Rosuvastatin From 5/45 mg Strength of ABT-143 Relative to That From the Coadministration of ABT-335 (Fenofibric Acid) 45 mg and Rosuvastatin Calcium 5 mg

Completed· AstraZeneca logo

AstraZeneca·Phase 1·NCT00826358·90 enrolled

Rosuvastatin Calcium Bioequivalence Study - Fast

Completed· GSK logo

GSK·Phase 1·NCT01711749·60 enrolled

Pilot Trial of Statin Use in Burn Patients

Completed·VVanderbilt University Medical Center·Phase 2·NCT00978419·40 enrolled

Effect of Rosuvastatin Response in Healthy Subjects: Potential Mechanisms of Anti-inflammatory Effects

Completed·UUniversity of Nebraska··NCT00874757·20 enrolled

Influence of Organic Anion Transporting Polypeptide1B1(OATP1B1) Genotype on Rosuvastatin PK, PD and Lipid Profiles

Completed·SSeoul National University Hospital·Phase 4·NCT01218347·34 enrolled

Effect of Rosuvastatin on Left Ventricular Remodeling

Completed·OOslo University Hospital·Phase 3·NCT00505154·75 enrolled

Vascular and Metabolic Effects of Rosuvastatin

Completed·GGachon University Gil Medical Center·Phase 4·NCT01660919·160 enrolled

ORBITAL: Open-Label Primary Care Study: Rosuvastatin Based Compliance Initiatives Linked To Achievement Of LDL Goals

Withdrawn· AstraZeneca logo

AstraZeneca·Phase 4·NCT00396240·1,294 enrolled

Effect of Vanzacaftor/Tezacaftor/Deutivacaftor (VNZ/TEZ/D-IVA) on the PK of Rosuvastatin in Healthy Participants

Active, not recruiting· Vertex Pharmaceuticals logo

Vertex Pharmaceuticals·Phase 1·NCT07349394·18 enrolled

A Study to Learn How Much Rosuvastatin Gets Into the Blood When Taken With or Without Elinzanetant and to Learn About the Safety of Elinzanetant in Healthy Participants

Completed· Bayer logo

Bayer·Phase 1·NCT04889287·16 enrolled

Rosuvastatin Effect on Serial Echocardiographic Measurement of Coronary Flow Velocity Reserve

Completed·—·Phase 4·NCT01490398·56 enrolled

A Study in Healthy People to Test Whether BI 3000202 Affects How 2 Other Medicines (Rosuvastatin and Digoxin) Are Taken up in the Body

Completed· Boehringer Ingelheim logo

Boehringer Ingelheim·Phase 1·NCT07215260·14 enrolled

Intensive Statin Therapy in Patients With AMI

Unknown status·—·Phase 2·NCT01923077·140 enrolled

A Study to Examine the Effect of Daridorexant on the Way the Body Absorbs, Distributes, and Gets Rid of Dabigatran and Rosuvastatin in Healthy Male Subjects

Completed· Idorsia Pharmaceuticals Ltd. logo

Idorsia Pharmaceuticals Ltd.·Phase 1·NCT05480475·24 enrolled

Impact of Rosuvastatin Doses on LDL Levels, CPK Levels and Aspartate Aminotransferase Levels

Completed·—·N/A·NCT06910098·195 enrolled

The Effects of Rosuvastatin on Running Training Adaptation and Safety

Not yet recruiting·TTaipei Medical University WanFang Hospital·N/A·NCT07401017·40 enrolled

Study to Compare the Bioavailability of ABT-335 and Rosuvastatin From ABT-143 Relative to That From the Co-administration of ABT-335 and Rosuvastatin Calcium

Completed· AstraZeneca logo

AstraZeneca·Phase 1·NCT00681395·64 enrolled

A Study in Healthy Men to Test the Influence of BI 1323495 on the Amount of the Medicines Rosuvastatin and Dabigatran in the Blood

Completed· Boehringer Ingelheim logo

Boehringer Ingelheim·Phase 1·NCT04257032·28 enrolled

The Effects of Rifampin on the Pharmacokinetics of Rosuvastatin

Completed·UUniversity of California, San Francisco·Phase 1·NCT02106767·16 enrolled

Pharmacokinetic (PK) Study of Single-dose Rosuvastatin and Tipranavir/Ritonavir in Healthy Subjects

Completed·JJohns Hopkins University·Phase 1·NCT00344123·29 enrolled

Effect of Coadministration of Sotorasib on the Pharmacokinetics of Rosuvastatin in Healthy Participants

Completed· Amgen logo

Amgen·Phase 1·NCT05045638·13 enrolled

Effect of Rosuvastatin on Triglyceride Levels in Mexican Hypertriglyceridemic Patients

Completed· AstraZeneca logo

AstraZeneca·Phase 4·NCT00473655·334 enrolled

Interaction24 trials

A Drug Drug Interaction (DDI) Study of Pirtobrutinib (LY3527727) and Rosuvastatin in Healthy Participants

Completed· Eli Lilly logo

Eli Lilly·Phase 1·NCT05176314·32 enrolled

A Two-part Study to Investigate the Interaction and Pharmacokinetics of GSK2586184

Completed· GSK logo

GSK·Phase 1·NCT01953835·37 enrolled

Drug Interaction Between Daclatasvir/Asunaprevir/BMS-791325 and Rosuvastatin

Completed· Bristol-Myers Squibb logo

Bristol-Myers Squibb·Phase 1·NCT02104843·18 enrolled

Show 21 more trials

The Pharmacokinetic Drug Interaction Between Rosuvastatin and Telmisartan/Amlodipine

Completed· Jeil Pharmaceutical Co., Ltd. logo

Jeil Pharmaceutical Co., Ltd.·Phase 1·NCT02387619·41 enrolled

PK Study to Assess Drug-drug Interaction and QTc Between Sitravatinib and a Cocktail of Substrates

Completed·MMirati Therapeutics Inc.·Phase 1·NCT04887194·40 enrolled

Drug-durg Interaction of SHR3680 With Digoxin, Rosuvastatin Calcium and Metformin Hydrochloride

Unknown status·JJiangsu HengRui Medicine Co., Ltd.·Phase 1·NCT04621669·18 enrolled

Drug-Drug Interaction Study of Rucaparib, Rosuvastatin and Oral Contraceptives

Completed·Ppharmaand GmbH·Phase 1·NCT03954366·36 enrolled

Drug-drug Interaction Between Digoxin, Furosemide, Metformin, and Rosuvastatin

Completed· Boehringer Ingelheim logo

Boehringer Ingelheim·Phase 1·NCT02231931·24 enrolled

A Pharmacokinetic Study to Evaluate the Drug Interaction Between HRS5091 and Probe Drugs in Healthy Volunteers

Completed·JJiangsu HengRui Medicine Co., Ltd.·Phase 1·NCT05273775·22 enrolled

A Drug-Drug Interaction Study of Orforglipron (LY3502970) in Healthy Overweight and Obese Participants

Completed· Eli Lilly logo

Eli Lilly·Phase 1·NCT06186622·50 enrolled

A Drug Drug Interaction (DDI) Study of Selpercatinib (LY3527723) and Rosuvastatin in Healthy Participants

Completed· Eli Lilly logo

Eli Lilly·Phase 1·NCT05906836·28 enrolled

To Evaluate the Pharmacokinetic Interactions and Safety Between Fimasartan and Rosuvastatin

Completed· Boryung Pharmaceutical Co., Ltd logo

Boryung Pharmaceutical Co., Ltd·Phase 1·NCT01921946·50 enrolled

Potential Drug Interaction Study Between Vemircopan and Rosuvastatin, Metformin, Levonorgestrel/Ethinyl Estradiol-containing Oral Contraceptives, and Carbamazepine

Completed· AstraZeneca logo

AstraZeneca·Phase 1·NCT06071442·60 enrolled

A Study to Evaluate the Drug-Drug Interaction of EDP-323 With Midazolam, Caffeine, and Rosuvastatin in Healthy Participants

Completed·EEnanta Pharmaceuticals, Inc·Phase 1·NCT06917508·24 enrolled

A Study to Assess the Drug-drug Interaction of BMS-963272 and Rosuvastatin

Completed· Bristol-Myers Squibb logo

Bristol-Myers Squibb·Phase 1·NCT04124003·28 enrolled

Assessment of Potential Interaction Between Ezetimibe and Rosuvastatin in Healthy Subjects With High Cholesterol (P03317)

Completed·OOrganon and Co·Phase 1·NCT00651144·40 enrolled

Drug-Drug Interaction Study Between EDP-938, Tacrolimus, Dabigatran, Rosuvastatin and Midazolam in Healthy Subjects

Completed·EEnanta Pharmaceuticals, Inc·Phase 1·NCT04498741·89 enrolled

Drug-drug Interaction Study of GSK1278863 With Pioglitazone, Rosuvastatin and Trimethoprim in Healthy Adult Volunteers

Completed· GSK logo

GSK·Phase 1·NCT02371603·70 enrolled

Drug-drug Interaction Study of Ganaplacide and Lumefantrine With Midazolam, Repaglinide, Dextromethorphan, Metformin, Rosuvastatin and Dolutegravir

Completed· Novartis logo

Novartis·Phase 1·NCT05236530·48 enrolled

Drug Interaction Study of MGL-3196 With Rosuvastatin and Simvastatin

Completed· Madrigal Pharmaceuticals logo

Madrigal Pharmaceuticals·Phase 1·NCT02542969·25 enrolled

Drug Interaction Statin

Completed· Bristol-Myers Squibb logo

Bristol-Myers Squibb·Phase 1·NCT02089061·26 enrolled

A Study to Investigate the Interaction of GSK1292263 With Rosuvastatin and Simvastatin in Healthy Subjects

Completed· GSK logo

GSK·Phase 1·NCT01101568·28 enrolled

A Phase 1 Study to Evaluate the Drug-Drug Interaction Potential Between ALG-055009 and Statin Therapy(Ies)

Completed·AAligos Therapeutics·Phase 1·NCT06191991·14 enrolled

Study to Evaluate the Pharmacokinetic Interaction and Safety After Multiple Oral Doses of Fimasartan/Amlodipine and Rosuvastatin in Healthy Male Subjects

Completed· Boryung Pharmaceutical Co., Ltd logo

Boryung Pharmaceutical Co., Ltd·Phase 1·NCT02397538·50 enrolled

Hypercholesterolemia7 trials

The Efficacy and Safety of Combination Therapy of Rosuvastatin and Ezetimibe and Rosuvastatin Monotherapy in Patients With Primary Hypercholesterolemia

Completed·SShin Poong Pharmaceutical Co. Ltd.·Phase 3·NCT03288038·382 enrolled

Compare the Efficacy of Rosuvastatin to Atorvastatin in High Risk Patients With Hypercholesterolemia

Completed· AstraZeneca logo

AstraZeneca·Phase 3·NCT00683618·934 enrolled

A Study to Compare Rosuvastatin/Ezetimibe and Rosuvastatin in Patients With Diabetes Mellitus and Hypercholesterolemia

Completed·YYuhan Corporation·Phase 4·NCT03217409·85 enrolled

Show 4 more trials

Evaluation of Ezetimibe and Atorvastatin Coadministration Versus Atorvastatin or Rosuvastatin Monotherapy in Japanese Patients With Hypercholesterolemia (Study P06027)(COMPLETED)

Completed·OOrganon and Co·Phase 4·NCT00871351·125 enrolled

Phase 3 Study to Evaluate the Efficacy and Safety of the DW0929 in Patients With Primary Hypercholesterolemia

Completed· Daewon Pharmaceutical Co., Ltd. logo

Daewon Pharmaceutical Co., Ltd.·Phase 3·NCT02390375·348 enrolled

A Clinical Trial to Assess the Long Term Safety and Tolerability of MK-0653H in Japanese Participants With Hypercholesterolemia (MK-0653H-833)

Completed·OOrganon and Co·Phase 3·NCT02748057·135 enrolled

Switching to Rosuvastatin Versus Adding Ezetimibe to Atorvastatin Versus Doubling the Dose of Atorvastatin in Patients With Hypercholesterolemia and Risk Factors (P03708)

Terminated·OOrganon and Co·Phase 4·NCT00651378·87 enrolled

Acute Coronary Syndrome5 trials

Comparison of Rosuvastatin and Atorvastatin in Patients With Acute Coronary Syndrome

Completed·QQueen's University·Phase 4·NCT00665834·18 enrolled

LUNAR IIIb Study Comparing Rosuvastatin and Atorvastatin in Subjects With Acute Coronary Syndromes

Completed· AstraZeneca logo

AstraZeneca·Phase 3·NCT00214630·825 enrolled

Effects in The ApoB/ApoA-I Ratio Using Rosuvastatin and Atorvastatin in Patients With Acute Coronary Syndrome

Completed· AstraZeneca logo

AstraZeneca·Phase 3·NCT00296387·1,160 enrolled

Show 2 more trials

Evaluation of Effect of Alirocumab on Coronary Atheroma Volume in Japanese Patients Hospitalized for Acute Coronary Syndrome With Hypercholesterolemia

Completed· Sanofi logo

Sanofi·Phase 4·NCT02984982·206 enrolled

LDL-C Lowering Efficacy and Safety of Rosuvastatin 20 mg/Day to10 mg/Day in Chinese ACS(Acute Coronary Syndrome) Patients

Unknown status·CCommittee of Cardio-Cerebral-Vascular Diseases of GSC·Phase 4·NCT02077257·1,060 enrolled

Atorvastatin5 trials

A Drug-drug Interaction Study Evaluating the PK Effects of Obicetrapib on Atorvastatin and Rosuvastatin

Completed·NNewAmsterdam Pharma·Phase 1·NCT06081166·74 enrolled

PULSAR - A Prospective Study to Evaluate the Utility of Low Doses of the Statins Atorvastatin and Rosuvastatin.

Completed· AstraZeneca logo

AstraZeneca·Phase 3·NCT00329173·1,000 enrolled

Polaris - Crestor 40 mg vs Atorvastatin 80 mg for 26 Weeks

Completed· AstraZeneca logo

AstraZeneca·Phase 3·NCT00653588

Show 2 more trials

Drug-Drug Interaction Study of Vadadustat With Rosuvastatin, Sulfasalazine, Pravastatin, Atorvastatin and Simvastatin

Completed·AAkebia Therapeutics·Phase 1·NCT03801733·134 enrolled

A Drug Interaction Study Between Simvastatin, Atorvastatin, Rosuvastatin, and GSK2248761 in Healthy Subjects.

Completed· GSK logo

GSK·Phase 1·NCT01138072·14 enrolled

92 more indications

Clinical Trial4 trials

A Clinical Trial of HRS-1301 on the Pharmacokinetics of Rosuvastatin Calcium Tablets in Healthy Subjects

Completed·SShandong Suncadia Medicine Co., Ltd.·Phase 1·NCT07097831·16 enrolled

A Clinical Trial to Evaluate the Pharmacokinetics and Safety of Fimasartan and Rosuvastatin in Healthy Male Subjects

Completed· Boryung Pharmaceutical Co., Ltd logo

Boryung Pharmaceutical Co., Ltd·Phase 1·NCT02704702·36 enrolled

A Clinical Trial to Investigate the Clinical Drug-Drug Interaction of Divarasib With Probe Substrates of P-Glycoprotein and Breast Cancer Resistance Protein in Healthy Participants

Completed· Roche logo

Roche·Phase 1·NCT06677957·19 enrolled

Show 1 more trial

Clinical Trial to Compare the Pharmacokinetics of DP-R208

Completed·AAlvogen Korea·Phase 1·NCT02707224·40 enrolled

Atherosclerosis3 trials

Rho Kinase in Patients With Atherosclerosis

Completed·—·Phase 3·NCT00115830·40 enrolled

Multicenter, Prospective, Randomized, Controlled, Double-blind Trial on the Impact of Rosuvastatin on Subclinical Markers of Atherosclerosis in Patients With Primary Necrotizing Vasculitides

Completed·AAssistance Publique - Hôpitaux de Paris·Phase 3·NCT02117453·121 enrolled

A phase3 Study Measuring the Effect of Rosuvastatin 20 mg on Carotid Intima-Media Thickness in Chinese Subjects With Subclinical Atherosclerosis

Completed· AstraZeneca logo

AstraZeneca·Phase 3·NCT02546323·543 enrolled

Coronary Artery Disease3 trials

Effect of Alirocumab(Proprotein Convertase Subtilisin/Kexin type9 Inhibitor) and Rosuvastatin or Rosuvastatin Alone on Lipid Core Plaques in Coronary Artery Disease Evaluated by Near-infrared Spectroscopy Intravascular Ultrasound

Unknown status·KKobe University·Phase 4·NCT03529253·30 enrolled

Pharmacodynamic Comparison of Rosuvastatin Versus Atorvastatin on Platelet Reactivity in Patients With Coronary Artery Disease on Dual Antiplatelet Therapy With New P2Y12 Inhibitors (Trial gRANADa)

Unknown status·UUniversity of Roma La Sapienza·Phase 4·NCT02030054·150 enrolled

Peking and Rotterdam on Mission to Reduce Coronary Artery Disease

Unknown status·PPeking University Third Hospital·N/A·NCT01653119·1,000 enrolled

Diabetes Mellitus3 trials

Efficacy and Safety of Berlim 25/10 Association in the Treatment of Type II Diabetes Mellitus and Dyslipidemia

Unknown status·EEMS·Phase 3·NCT04603508·240 enrolled

Efficacy and Safety of Berlim 25/20 Association in the Treatment of Type II Diabetes Mellitus and Dyslipidemia.

Recruiting·EEMS·Phase 3·NCT04602754·228 enrolled

The Impact of Rosuvastatin on the Density Score of Coronary Artery Calcification in CAD Patients With Diabetes Mellitus

Unknown status·SSir Run Run Shaw Hospital·Phase 4·NCT02418884·122 enrolled

Efficacy and Safety3 trials

Evaluation of the Efficacy and Safety of Rosuvastatin 5 mg Versus Pravastatin 40 mg and Atorvastatin 10 mg in Type IIa and IIb Hypercholesterolaemic Patients

Completed· AstraZeneca logo

AstraZeneca·Phase 4·NCT00631189·668 enrolled

Study of the Efficacy and Safety of Alirocumab (REGN727/SAR236553) in Combination With Other Lipid-modifying Treatment (LMT) (ODYSSEY OPTIONS I)

Completed· Regeneron logo

Regeneron·Phase 3·NCT01730040·355 enrolled

48-wk Open Label Phase IIIb to Evaluate Efficacy and Safety

Completed· AstraZeneca logo

AstraZeneca·Phase 3·NCT00654602·1,500 enrolled

Breast Cancer3 trials

Dose Optimization of Rosuvastatin in Early Stage and Metastatic Estrogen Receptor Positive Breast Cancer Patients on Endocrine Therapy

Withdrawn·—·Phase 1·NCT02483871

Drug-drug Interaction Study Using Rosuvastatin as a Breast Cancer Resistant Protein (Efflux Transporter), Organic Anion-transporting Polypeptide (OATP)1B1, and OATP1B3 (Uptake Transporters) Probe Substrate

Completed· Bayer logo

Bayer·Phase 1·NCT02671097·30 enrolled

Identification and Validation of Biomarkers for Breast Cancer Resistance Protein (BCRP)

Completed·UUniversity of California, San Francisco·Phase 1·NCT04542382·11 enrolled

Chronic Periodontitis3 trials

Locally Delivered Atorvastatin & Rosuvastatin for Treatment of Furcation Defects in Chronic Periodontitis

Completed·GGovernment Dental College and Research Institute, Bangalore·Phase 2/3·NCT02800902·90 enrolled

Locally Delivered Metformin & Rosuvastatin for Treatment of Intrabony Defects in Chronic Periodontitis

Completed·GGovernment Dental College and Research Institute, Bangalore·Phase 2/3·NCT03204058·90 enrolled

Efficacy of Locally Delivred 1.2% Rosuvastatin Gel in Chronic Periodontitis

Completed·GGovernment Dental College and Research Institute, Bangalore·Phase 2/3·NCT02283515·65 enrolled

Metformin2 trials

A Study to Assess the Effect of Povorcitinib on Digoxin, Rosuvastatin, and Metformin Pharmacokinetics and the Effect of Probenecid on Povorcitinib Pharmacokinetics When Administered Orally to Healthy Adult Participants

Completed· Incyte logo

Incyte·Phase 1·NCT06416800·71 enrolled

A Study in Healthy Men to Test Whether Zongertinib Influences the Amount of 4 Other Medicines (Dabigatran, Rosuvastatin, Metformin, and Furosemide) in the Blood

Completed· Boehringer Ingelheim logo

Boehringer Ingelheim·Phase 1·NCT06504862·32 enrolled

Endothelial Function2 trials

Rosuvastatin and Renal Endothelial Function

Completed·UUniversity of Erlangen-Nürnberg Medical School·Phase 2·NCT00160745·46 enrolled

Effect of Rosuvastatin on Endothelial Function

Terminated·UUniversity of Hawaii·Phase 2/3·NCT00986999·7 enrolled

Type 2 Diabetes2 trials

Dapagliflozin and Cholesterol Metabolism in Type 2 Diabetes (DM2)

Completed·AAmsterdam UMC, location VUmc·Phase 4·NCT03074630·12 enrolled

LIpid Lowering With Highly Potent Statins in Hyperlipidaemia With Type 2 Diabetes patiENts

Completed·LListen Trial Group·N/A·NCT01544309·1,049 enrolled

Treatment2 trials

Rosuvastatin Pre-Treatment Influences the Risk of Coronary Intervention Study

Unknown status·—·Phase 3·NCT01378715·400 enrolled

Effect of Intensive Lipid Lowering Treatment Compared to Moderate Lipid Lowering Treatment on Carotid Intima-media Thickness (CIMT)

Completed·OOdense University Hospital·Phase 4·NCT01203982·87 enrolled

Safety and Efficacy2 trials

A Multicenter Study Comparing the Safety and Efficacy of ABT-335 and Rosuvastatin Calcium Combination Therapy to Monotherapy in Subjects With Dyslipidemia

Completed· AstraZeneca logo

AstraZeneca·Phase 3·NCT00463606·760 enrolled

Evaluate Safety and Efficacy of ABT-335 in Combination With Rosuvastatin Calcium in Subjects With Multiple Abnormal Lipid Levels in the Blood

Completed·AAbbott·Phase 3·NCT00300482·1,445 enrolled

Overweight2 trials

A Study to Learn How the Study Medicine Danuglipron is Taken Up Into the Blood and If Danuglipron Changes How the Body Processes Other Study Medicines (Atorvastatin and Rosuvastatin) in Healthy Adults Who Are Overweight or Obese

Completed· Pfizer logo

Pfizer·Phase 1·NCT06567327·82 enrolled

Influence of JY09 on Pharmacokinetics of Metformin , Rosuvastatin , and Digoxin and the QT Interval Study in Overweight Chinese Subjects

Completed·BBeijing Dongfang Biotech Co., Ltd.·Phase 1·NCT06247748·28 enrolled

Cholesterol2 trials

Study of High Density Lipoprotein Cholesterol (HDL-C)-Raising Mechanism of Rosuvastatin (CRESTOR™) by Quantifying the Key Steps of Reverse Cholesterol Transport (RCT)

Completed· AstraZeneca logo

AstraZeneca·Phase 3·NCT00240266·15 enrolled

KF2019#1-trial: Effects of a Thrombocyte Inhibitor on a Cholesterol-lowering Drug

Unknown status·HHelsinki University Central Hospital·Phase 1·NCT05373277·10 enrolled

Tics2 trials

A Study to Compare the Pharmacokinetics of DP-R207 in Comparison to Each Component Administered Alone

Completed·AAlvogen Korea·Phase 1·NCT02730689·66 enrolled

Evaluate the Effect of Vimseltinib on the Pharmacokinetics of a BCRP and OATP1B1 Substrate

Completed·DDeciphera Pharmaceuticals, LLC·Phase 1·NCT07158398·20 enrolled

Acute Kidney Injury2 trials

Rosuvastatin Prevent Contrast Induced Acute Kidney Injury in Patients With Diabetes

Completed·SShenyang Northern Hospital·Phase 4·NCT00786136·2,998 enrolled

Atorvastatin Versus Rosuvastatin on Contrast Induced Acute Kidney Injury (PRATO-ACS 2)

Completed·CCentro Cardiopatici Toscani·Phase 4·NCT01870804·760 enrolled

Cardiovascular2 trials

Depression and Cardiovascular Risk Markers: Effects of Rosuvastatin Therapy

Withdrawn·UUniversity Hospital, Akershus·Phase 2·NCT00951132

Effect of Rosuvastatin on Coronary Flow Reserve in Hypertensive Patients With Cardiovascular Risk

Completed·—·Phase 4·NCT02482207·96 enrolled

Sepsis2 trials

Statins for Acutely Injured Lungs From Sepsis

Terminated·NNational Heart, Lung, and Blood Institute (NHLBI)·Phase 3·NCT00979121·745 enrolled

Effect of Rosuvastatin in Abdominal Sepsis

Unknown status·UUniversidad Autonoma de San Luis Potosí·Phase 2·NCT00357123·60 enrolled

Cardiovascular Disease2 trials

RAndomized Comparison of Efficacy and Safety of Lipid-lowerING With Statin Monotherapy Versus Statin/Ezetimibe Combination for High-risk Cardiovascular Diseases (RACING Trial)

Unknown status·YYonsei University·N/A·NCT03044665·3,780 enrolled

Ezetimibe/Simvastatin (MK-0653A) Versus Rosuvastatin Versus Doubling Statin Dose in Participants With Cardiovascular Disease and Diabetes Mellitus (MK-0653A-133)(COMPLETED)

Completed·OOrganon and Co·Phase 3·NCT00862251·808 enrolled

Efficacy2 trials

OLE Study to Evaluate Safety / Efficacy of ZD4522

Completed· AstraZeneca logo

AstraZeneca·Phase 3·NCT00654303·3,500 enrolled

Compare the Safety & Efficacy of Rosuvastatin 40mg in Combination With Ezetimibe 10mg

Completed· AstraZeneca logo

AstraZeneca·Phase 3·NCT00653445

Heart Disease2 trials

Assessment of the Lipid Lowering Effect of Rosuvastatin Compared to Atorvastatin in Subjects With Coronary Heart Disease

Completed· AstraZeneca logo

AstraZeneca·Phase 4·NCT00235950·255 enrolled

Rosuvastatin in the Long-term Treatment of Hypercholesterolaemic Subjects With Coronary Heart Disease

Completed· AstraZeneca logo

AstraZeneca·Phase 4·NCT00329160·214 enrolled

Drug Interactions2 trials

A Study to Evaluate the Drug-drug Interactions (DDIs) of GP681 With Rosuvastatin, Digoxin, Itraconazole, Oseltamivir in Chinese Healthy Volunteers

Completed·JJiangxi Qingfeng Pharmaceutical Co. Ltd.·Phase 1·NCT05789342·54 enrolled

Study to Evaluate Organic Anion Transporting Polypeptide (OATP) Transporter-Mediated Drug-Drug Interactions Between Filgotinib and Statins as Probe Drugs in Healthy Participants

Completed· Gilead logo

Gilead·Phase 1·NCT04608344·27 enrolled

Intracerebral Hemorrhage2 trials

Effect of Rosuvastatin in Intracerebral Hemorrhage

Completed·UUniversidad Autonoma de San Luis Potosí·Phase 2·NCT00364559·75 enrolled

Statins in Patients With Spontaneous Intracerebral Hemorrhage

Completed·PPomeranian Medical University Szczecin·N/A·NCT06094244·153 enrolled

Preeclampsia2 trials

Rosuvastatin in Order to Induce Preeclampsia Resolution in Severe PET up to 48 Hours Following Delivery

Unknown status·SSoroka University Medical Center·Phase 1/2·NCT02314286·100 enrolled

Effect of Rosuvastatin on the Clinical Features of Preeclampsia

Unknown status·—·Phase 2·NCT04303806·80 enrolled

Metabolic Syndrome1 trial

A Study to Investigate the Effect of Rosuvastatin (CRESTOR®) on High Density Lipoprotein Kinetics in Patients With the Metabolic Syndrome

Completed· AstraZeneca logo

AstraZeneca·Phase 3·NCT00240305·15 enrolled

Deep Vein Thrombosis1 trial

Mechanisms of Deep Vein Thrombosis (DVT) and Vein Wall Fibrosis

Unknown status·KKhanh Nguyen·Phase 1/2·NCT04833764·30 enrolled

Midazolam1 trial

A Study to Evaluate the Effects of Tedizolid Phosphate on the Pharmacokinetics and Safety of Midazolam and Rosuvastatin (MK-1986-004)

Completed· Merck & Co. logo

Merck & Co.·Phase 1·NCT02477514·18 enrolled

Effectiveness1 trial

Effectiveness of Statins on Lipid Goal Attainment and Lipid Parameters in PCI Patients

Withdrawn· AstraZeneca logo

AstraZeneca··NCT02561845

Carotid Artery Atheroma1 trial

Progression of Carotid Artery Atheroma in Moderately Hypercholesterolemic Subjects

Completed· AstraZeneca logo

AstraZeneca·Phase 3·NCT00654394·200 enrolled

Aortic Stenosis1 trial

Effects of Rosuvastatin on Aortic Stenosis Progression

Completed· AstraZeneca logo

AstraZeneca·Phase 3·NCT00800800·378 enrolled

Prevention1 trial

Heart Outcomes Prevention Evaluation-3

Completed·PPopulation Health Research Institute·Phase 4·NCT00468923·12,705 enrolled

Statins1 trial

Effects of Inclisiran Combined With Statins on the Morphology of Coronary Vulnerable Plaques

Recruiting·NNanjing First Hospital, Nanjing Medical University·Phase 4·NCT06338293·40 enrolled

Glaucoma1 trial

Effect of Rosuvastatin on Endothelial Function in Patients With Diabetes and Glaucoma

Withdrawn·MMedical University of Vienna·Phase 4·NCT00913562

Portal Hypertension1 trial

Propranolol, Carvedilol and Rosuvastatin in the Prevention of Variceal Bleeding in Cirrhotic Portal Hypertension

Unknown status·UUniversidade Federal do Rio de Janeiro·Phase 2/3·NCT03720067·80 enrolled

Outcome1 trial

ROsuvastatin LOading and Clinical Outcomes Trial

Completed·—·Phase 3·NCT01936805·299 enrolled

Hypercholesterolaemia1 trial

An Study to Evaluate Rosuvastatin in Children and Adolescents With Familial Hypercholesterolaemia

Completed· AstraZeneca logo

AstraZeneca·Phase 3·NCT01078675·315 enrolled

Mixed Dyslipidemia1 trial

A Year 2, Safety Extension Study of the Combination of ABT-335 and Statin Therapy for Subjects With Mixed Dyslipidemia

Completed·AAbbott·Phase 3·NCT00491530·310 enrolled

Venous Thromboembolism1 trial

Statins for Venous Event Reduction in Patients With Venous Thromboembolism

Recruiting·OOttawa Hospital Research Institute·Phase 3·NCT04319627·2,700 enrolled

Arteriovenous Fistula1 trial

Vascular Protective Effect of Rosuvastatin in Arteriovenous Fistula

Completed·NNational Cheng-Kung University Hospital·Phase 2·NCT01863914·60 enrolled

Insulin resistance1 trial

Effect of Pioglitazone on Insulin Resistance, Atherosclerosis Progression and Clinical Course of Coronary Heart Disease

Completed·UUkrainian Medical Stomatological Academy·Phase 4·NCT03011775·43 enrolled

Cytokines1 trial

Rosuvastatin Impact on Ventricular Remodelling Lipids and Cytokines

Completed· AstraZeneca logo

AstraZeneca·Phase 3·NCT00240292·160 enrolled

Intravascular Ultrasound1 trial

A Study To Evaluate the Effect of Rosuvastatin On Intravascular Ultrasound-Derived Coronary Atheroma Burden (ASTEROID)

Completed· AstraZeneca logo

AstraZeneca·Phase 3·NCT00240318·450 enrolled

Elderly1 trial

A Clinical Study to Evaluate PK, PD, and PG of Rosuvastatin in the Elderly

Completed·SSeoul National University Hospital·Phase 1·NCT03715101·20 enrolled

Chronic Kidney Disease1 trial

30 Week Study of the Combination of ABT-335 and Rosuvastatin Compared to Rosuvastatin Monotherapy for Subjects With Dyslipidemia and Stage 3 Chronic Kidney Disease

Completed· AstraZeneca logo

AstraZeneca·Phase 3·NCT00680017·280 enrolled

Effect of Drug1 trial

Study to Learn the Effect of Drug BAY1817080 on the Way the Body Absorbs, Distributes and Excretes Another Drug Rosuvastatin in Healthy Adult Participants

Completed· Bayer logo

Bayer·Phase 1·NCT04252300·14 enrolled

Metabolic Disease1 trial

Statin Monotherapy for Treatment of Endocrine Metabolic Disease Risk

Unknown status·—·Phase 2·NCT03113994·8 enrolled

Heart Failure1 trial

Comparison of Lipophilic Versus Hydrophilic Statins on Patients With Heart Failure

Completed·—·Phase 4·NCT03255044·85 enrolled

Endothelial Dysfunction1 trial

Short Term Statin Treatment and Endothelial Dysfunction Due to Ischemia and Reperfusion Injury

Completed·RRadboud University Medical Center·Phase 4·NCT00987974·48 enrolled

Magnetic Resonance Imaging1 trial

Resuvastatin Treatment for Symptomatic Middle Cerebral Artery Stenosis Based on High-resolution Magnetic Resonance Imaging

Completed·—·Phase 4·NCT02041117·162 enrolled

Hyperlipidemia1 trial

Efficacy and Safety Study of YH16410 Versus Rosuvastatin and Telmisartan Monotherapies in Patients With Hypertension and Hyperlipidemia

Completed·YYuhan Corporation·Phase 3·NCT01914432·210 enrolled

Nephropathy1 trial

Statin Contrast Induced Nephropathy Prevention

Completed·CCentro Cardiopatici Toscani·Phase 4·NCT01185938·500 enrolled

Head Injury1 trial

Effect of Rosuvastatin on Amnesia and Orientation Through Galveston Outcome Amnesia Test in Moderate Head Injury

Completed·UUniversidad Autonoma de San Luis Potosí·Phase 2·NCT00329758·20 enrolled

Rheumatoid Arthritis1 trial

Rosuvastatin in Rheumatoid Arthritis (RORA)

Completed·UUniversity of Dundee·Phase 2/3·NCT00679510·50 enrolled

Necrosis1 trial

Rosuvastatin in Preventing Myonecrosis in Elective Percutaneous Coronary Interventions (PCIs)

Completed·UUniversity of Roma La Sapienza·Phase 3·NCT01007279·160 enrolled

Chest pain1 trial

Women With Chest Pain and no Significant Coronary Artery Stenosis; A Study on Microvascular Resistance

Completed·OOslo University Hospital·Phase 4·NCT01582165·66 enrolled

Caffeine1 trial

To Determine the Effect of KP-001 on Rosuvastatin, Caffeine PK and the Effect of Fluvoxamine on KP-001 PK in Volunteers

Completed·KKaken Pharmaceutical·Phase 1·NCT06821698·38 enrolled

Lip1 trial

Type III Dysbetalipoproteinemia

Completed· AstraZeneca logo

AstraZeneca·Phase 3·NCT00214604·30 enrolled

Plaque1 trial

CT COMPARE: CT Coronary Angiography to Measure Plaque Reduction

Terminated·NNational Heart, Lung, and Blood Institute (NHLBI)·Phase 4·NCT02740699·79 enrolled

Patients With Advanced Solid Tumors1 trial

A Phase 1 Study to Evaluate the Potential Drug Interactions Between Repotrectinib and Metformin, Digoxin, and Rosuvastatin in Patients With Advanced Solid Tumors

Withdrawn·TTurning Point Therapeutics, Inc.·Phase 1·NCT05828303

Methotrexate1 trial

A Study Investigating Interactions Between BMS-986322 and Rosuvastatin, Metformin and Methotrexate in Healthy Participants

Completed· Bristol-Myers Squibb logo

Bristol-Myers Squibb·Phase 1·NCT05615012·76 enrolled

Venous thrombosis1 trial

Rosuvastatin Use to Improve the Coagulation Profile in Patients With Venous Thrombosis

Completed·LLeiden University Medical Center·N/A·NCT01613794·255 enrolled

Proteinuria1 trial

Prospective Evaluation of Proteinuria and Renal Function in Non-diabetic Patients With Progressive Renal Disease

Completed· AstraZeneca logo

AstraZeneca·Phase 2·NCT00296400·237 enrolled

Elective1 trial

Statins and Selective Cyclooxygenase-2 Receptor Inhibitors in Blunt Chest Trauma

Unknown status·TTel-Aviv Sourasky Medical Center·N/A·NCT01623921·100 enrolled

Platelet Reactivity1 trial

Pharmacodynamic Effects of Atorvastatin vs. Rosuvastatin on Platelet Reactivity

Unknown status·UUniversity of Roma La Sapienza·Phase 4·NCT01567774·100 enrolled

Type 2 Diabetic Patients1 trial

Evaluate the Efficacy and Safety of Rosuvastatin Versus Simvastatin in Type 2 Diabetic Patients With Dyslipidemia

Completed·TTaipei Veterans General Hospital, Taiwan·Phase 4·NCT00506961·90 enrolled

Alcoholic Fatty Liver Disease1 trial

Phase IV Study to Evaluate the Effects of Statin Monotherapy or Statin / Ezetimibe Combination Therapy on Hepatic Steatosis in Patients With Hyperlipidemia and Nonalcoholic Fatty Liver Disease

Completed·YYonsei University·Phase 4·NCT03434613·64 enrolled

COVID-191 trial

Effectiveness and Safety of Medical Treatment for SARS-CoV-2 (COVID-19) in Colombia

Completed·UUniversidad Nacional de Colombia·Phase 2/3·NCT04359095·650 enrolled

Elderly Patients1 trial

Effect of Atorvastatin Versus Rosuvastatin Intensive Statin Regimens on Chinese Elderly Patients Undergoing PCI

Unknown status·—·Phase 4·NCT01646307·1,000 enrolled

Brain Injury1 trial

Effect of Rosuvastatin on Cytokines After Traumatic Brain Injury

Completed·UUniversidad Autonoma de San Luis Potosí·Phase 1/2·NCT00990028·40 enrolled

Coronary Atherosclerosis1 trial

Polygenic Risk-based Detection of Subclinical Coronary Atherosclerosis and Intervention With Statin and Colchicine

Recruiting·MMassachusetts General Hospital·Phase 4·NCT05850091·200 enrolled

Obesity1 trial

Study To Evaluate The Effect Of Two Steady State Doses of PF 06882961 On Rosuvastatin And Midazolam Pharmacokinetics In Otherwise Healthy Adult Participants With Obesity

Completed· Pfizer logo

Pfizer·Phase 1·NCT04621227·16 enrolled

Transplant Recipient1 trial

The Rosuvastatin In TrAnsplant Recipients Study

Completed·UUniversity of Oslo School of Pharmacy·Phase 4·NCT01524601·20 enrolled

Optical Coherence Tomography1 trial

Evaluation of Statin-induced Lipid-rich Plaque Progression by Optical Coherence Tomography (OCT) Combined With Intravascular Ultrasound (IVUS)

Completed·HHarbin Medical University·Phase 4·NCT01023607·120 enrolled

Cardiac Surgery1 trial

Statin Therapy In Cardiac Surgery

Completed·UUniversity of Oxford·Phase 4·NCT01573143·1,922 enrolled

Sexual Function1 trial

Statin Lowering Testosterone and Sexual Function

Completed·—·Phase 4·NCT02612714·151 enrolled

Pediatric1 trial

PLUTO: Pediatric Lipid-redUction Trial of rOsuvastatin

Completed· AstraZeneca logo

AstraZeneca·Phase 3·NCT00355615·173 enrolled

Friedreich ataxia1 trial

Rosuvastatin (Crestor) in Friedreich Ataxia

Completed·—·Phase 1·NCT02705547·12 enrolled

Concentration1 trial

Clinical Study to Investigate the Effect of Macitentan on the Concentrations of Rosuvastatin in the Blood of Healthy Male Subjects

Completed· Johnson & Johnson logo

Johnson & Johnson·Phase 1·NCT03359291·20 enrolled

Major Adverse Cardiac Events1 trial

Primary Prevention of Major Adverse Cardiac Events (MACE) With Standard and Intensive Statin Treatment in Patients With Diabetes: Survival and Cardiovascular Event Assessments

Terminated·PPositive Trial Group·N/A·NCT01173939·10,000 enrolled

Cardiomyopathy1 trial

Colchicine Versus Beta-blockers, Angiotensin-converting Enzyme Inhibitors, and Statins for Prevention of Chemotherapy-Induced Cardiomyopathy

Not yet recruiting·—·Phase 1·NCT06304896·150 enrolled

Advanced Solid Tumors1 trial

Pharmacokinetic Drug-drug Interaction Study of Encorafenib and Binimetinib on Probe Drugs in Patients With BRAF V600-mutant Melanoma or Other Advanced Solid Tumors

Completed· Pfizer logo

Pfizer·Phase 1·NCT03864042·56 enrolled

Hepatitis C1 trial

Rosuvastatin for Hepatitis C

Withdrawn·UUMC Utrecht·N/A·NCT00371579

Ulcerative Colitis1 trial

Drug Repurposing - Statins as Microbiota Modulating Agents in Ulcerative Colitis

Terminated·UUniversitaire Ziekenhuizen KU Leuven·Phase 2/3·NCT04883840·177 enrolled

Complication1 trial

Rosuvastatin for Preventing Complications in Renal Ablation

Unknown status·UUniversity of Roma La Sapienza·Phase 4·NCT01899027·112 enrolled

Hip Fracture1 trial

Statin in Hip Fracture

Terminated·UUniversity Hospital, Brest·Phase 3·NCT01494090·36 enrolled

Systemic Lupus Erythematosus1 trial

Efficacy and Adverse Effect of Simvastatin Compare to Rosuvastatin in Systemic Lupus Erythematosus (SLE) Patients With Corticosteroid Therapy and High Low-Density Lipoprotein (LDL) Cholesterol Level

Unknown status·RRamathibodi Hospital·Phase 4·NCT00866229·140 enrolled

Ischemic stroke1 trial

Statins Role in Acute Ischemic Stroke

Not yet recruiting·—··NCT06371495·105 enrolled

Percutaneous Coronary Intervention1 trial

Evaluation of Platelet Function After Statin Loading Dose in Patients Before Percutaneous Coronary Intervention

Completed·IIRCCS San Raffaele·Phase 2·NCT01526460·146 enrolled

Overweight or Obese1 trial

A Drug-Drug Interaction Study to Estimate the Effect of PF-07081532 on the Pharmacokinetics of Dabigatran and Rosuvastatin in Overweight or Obese Adult Participants

Terminated· Pfizer logo

Pfizer·Phase 1·NCT05788328·16 enrolled

Ischemia1 trial

Does Caffeine Reduce Rosuvastatin-Induced Protection Against Ischemia-Reperfusion Injury?

Completed·RRadboud University Medical Center·Phase 4·NCT00457652·24 enrolled

Renal artery stenosis1 trial

Compare Effects of Intensive Versus Conventional Lipid-lowering Therapy in Patients With Severe Atherosclerotic Renal Artery Stenosis Undergoing Stent Placement

Completed·—·Phase 2/3·NCT03521700·150 enrolled

Unspecified3 trials

DP-R212 Pharmacokinetic Study

Unknown status·AAlvogen Korea·Phase 1·NCT02789475·38 enrolled

A Study of Lasmiditan in Healthy Volunteers

Completed· Eli Lilly logo

Eli Lilly·Phase 1·NCT04749914·97 enrolled

DP-R212 Pharmacokinetic Study Phase I

Unknown status·AAlvogen Korea·Phase 1·NCT02814500·36 enrolled

Regulatory

FDA Approval Timeline[5]

Aug 12, 2003

CRESTOR

NDA NDA021366

Dec 18, 2018

EZALLOR SPRINKLE

NDA NDA208647

Sources

References

[1]
ClinicalTrials.gov — 537 trial records for rosuvastatin. U.S. National Library of Medicine, National Institutes of Health.
[2]
MedlinePlus Drug Information — Crestor drug information. U.S. National Library of Medicine, National Institutes of Health.
[3]
ChEMBL — rosuvastatin compound record. European Bioinformatics Institute (EMBL-EBI).
[4]
Open Targets Platform — Drug–disease associations for rosuvastatin. EMBL-EBI & Wellcome Sanger Institute.
[5]
OpenFDA — FDA approval records (NDA NDA208647). U.S. Food & Drug Administration.
[6]
FDA Orange Book — Patent and exclusivity data for Crestor. U.S. Food & Drug Administration.
[7]
SEC EDGAR — AstraZeneca company filings. U.S. Securities and Exchange Commission.

Details

Drug Info

Quick Facts

Mechanism of Action: HMG-Coa Reductase Inhibitor[3]
Modality: Small molecule[3]
Highest Phase: Approved[1]
Company: AstraZeneca

Patent Landscape[6]

Patent Cliff

Feb 12, 2036

Earliest patent expiration — generic entry possible after this date

Patent #Expires

10413543Feb 12, 2036