Crestor

(rosuvastatin)

ApprovedSmall molecule

Rosuvastatin is used to lower cholesterol and triglycerides in the blood, which helps reduce the risk of heart disease and stroke.[2] Crestor is currently approved and in use across 109 indications[4].[1]

Crestor is one of 1941 small molecule programs targeting Insulin resistance. It is currently in Approved.

109

Indications

520

Total Trials

Active Trials

1,940

Competitors

FDA Applications

NDA/BLA/ANDA regulatory filings

Patents

Pipeline

Status by Indication[4][1]

Indication

Insulin ResistanceActive, not recruiting

Coronary Artery DiseaseApproved

Metabolic SyndromeApproved

HIV InfectionApproved

Systemic Lupus ErythematosusActive, not recruiting

Disorder of Lipid MetabolismApproved

Cardiovascular DiseaseActive, not recruiting

Endothelial DysfunctionActive, not recruiting

Renal Artery StenosisActive, not recruiting

Essential HypertensionActive, not recruiting

Insulin ResistanceApproved

Active, not recruiting

Coronary Artery DiseaseApproved

Approved

Metabolic SyndromeApproved

Approved

HIV InfectionApproved

Approved

Systemic Lupus ErythematosusPhase 2

Active, not recruiting

Disorder of Lipid MetabolismApproved

Approved

Cardiovascular DiseaseApproved

Active, not recruiting

Endothelial DysfunctionApproved

Active, not recruiting

Renal Artery StenosisPhase 2/Phase 3

Active, not recruiting

Essential HypertensionPhase 3

Active, not recruiting

Showing 10 of 108 indications

Competition

Competitive Landscape

2828 competitors in Breast Cancer

#DrugCompanyPhaseTrials

Crestor

AstraZeneca

Approved

5 2

Halaven

Eisai

Preclinical

38 3

Lexiscan

Astellas

Preclinical

1 4

Sporanox

SSebela Pharmaceuticals Development LLC

Preclinical

1 5

Aquasol E

NNational Eye Institute (NEI)

Preclinical

—6

QS21

MMemorial Sloan Kettering Cancer Center

Preclinical

3 7

Neoadjuvant Therapy

SSun Yat-sen University

Preclinical

3 8

Perflutren Lipid Microsphere

IImaRx Therapeutics

Preclinical

1 9

Recombinant Human Endostatin

PPeking University Third Hospital

Preclinical

1 10

Dextromethorphan Hydrobromide

Boehringer Ingelheim

Preclinical

Ranked by pipeline maturity and clinical activity. Current drug highlighted in teal.

Timeline

Expected Milestones

Q3 2026

Phase 2Recruiting

Dyslipidaemia

NCT07218900

Q1 2027

Phase 2/3Recruiting

Dyslipidaemia

NCT06834932

Q4 2028

Phase 3Not yet recruiting

Cardiovascular Events

NCT07474649

Q3 2029

Phase 2Recruiting

Cirrhosis

NCT05832229

Clinical

Trials by Indication[1]

Statin30 trials

A Study in Healthy Men to Test the Influence of BI 1358894 on the Amount of the Medicines Rosuvastatin and Dabigatran in the Blood

Completed· Boehringer Ingelheim logo

Boehringer Ingelheim·Phase 1·NCT04099732·26 enrolled

Pharmacokinetic Study of Rosuvastatin and Lopinavir/Ritonavir in HIV Patients

Completed·RRadboud University Medical Center·Phase 2·NCT00184951·30 enrolled

Rosuvastatin ORBITAL Germany

Completed· AstraZeneca logo

AstraZeneca·Phase 3·NCT00379249·8,000 enrolled

Show 27 more trials

A Study in Healthy Male Subjects to Investigate Whether Administration of ACT-541468 Can Affect the Fate in the Body (Amount and Time of Presence in the Blood) of Rosuvastatin

Completed· Idorsia Pharmaceuticals Ltd. logo

Idorsia Pharmaceuticals Ltd.·Phase 1·NCT03339752·20 enrolled

Comparison of the Bioavailability of Fenofibric Acid and Rosuvastatin From 5/45 mg Strength of ABT-143 Relative to That From the Coadministration of ABT-335 (Fenofibric Acid) 45 mg and Rosuvastatin Calcium 5 mg

Completed· AstraZeneca logo

AstraZeneca·Phase 1·NCT00826358·90 enrolled

The Effects of Rifampin on the Pharmacokinetics of Rosuvastatin

Completed·UUniversity of California, San Francisco·Phase 1·NCT02106767·16 enrolled

Pilot Trial of Statin Use in Burn Patients

Completed·VVanderbilt University Medical Center·Phase 2·NCT00978419·40 enrolled

Influence of OATP1B1 and BRCP Genotype on Rosuvastatin PK, PD and Lipidomics in Hyperlipidemic Patients

Completed·SSeoul National University Hospital·Phase 4·NCT01466608·21 enrolled

IIIb 6 Week Open Label Multicentre Rosuvastatin & Simvastatin

Completed· AstraZeneca logo

AstraZeneca·Phase 3·NCT00654446·442 enrolled

Effect of Coadministration of Sotorasib on the Pharmacokinetics of Rosuvastatin in Healthy Participants

Completed· Amgen logo

Amgen·Phase 1·NCT05045638·13 enrolled

Effect of Rosuvastatin Response in Healthy Subjects: Potential Mechanisms of Anti-inflammatory Effects

Completed·UUniversity of Nebraska··NCT00874757·20 enrolled

A Study to Assess the Drug Levels of CC-92480 After Coadministration With Rifampin and Itraconazole, and the Drug Levels of Digoxin and Rosuvastatin After Coadministration With CC-92480 in Healthy Participants

Completed· Bristol-Myers Squibb logo

Bristol-Myers Squibb·Phase 1·NCT05389722·24 enrolled

Influence of Organic Anion Transporting Polypeptide1B1(OATP1B1) Genotype on Rosuvastatin PK, PD and Lipid Profiles

Completed·SSeoul National University Hospital·Phase 4·NCT01218347·34 enrolled

Rosuvastatin Affecting Aortic Valve Endothelium

Completed·—··NCT00114491·200 enrolled

Effect of Rosuvastatin on Triglyceride Levels in Mexican Hypertriglyceridemic Patients

Completed· AstraZeneca logo

AstraZeneca·Phase 4·NCT00473655·334 enrolled

Study to Compare the Bioavailability of ABT-335 and Rosuvastatin From ABT-143 Relative to That From the Co-administration of ABT-335 and Rosuvastatin Calcium

Completed· AstraZeneca logo

AstraZeneca·Phase 1·NCT00681395·64 enrolled

A Study in Healthy Men to Test the Influence of BI 1323495 on the Amount of the Medicines Rosuvastatin and Dabigatran in the Blood

Completed· Boehringer Ingelheim logo

Boehringer Ingelheim·Phase 1·NCT04257032·28 enrolled

A Study to Learn About How BAY2927088 Affects the Level of Dabigatran or Rosuvastatin in the Blood When These Drugs Are Taken Together in Healthy Participants

Completed· Bayer logo

Bayer·Phase 1·NCT06329895·15 enrolled

Evaluating Bioequivalence of a Fixed Dose Combination Versus Tablets of Bempedoic Acid / Ezetimibe and Rosuvastatin

Completed· Daiichi Sankyo logo

Daiichi Sankyo·Phase 1·NCT07201545·58 enrolled

The Effects of Statin Therapy on Coronary Flow Reserve and Inflammatory Markers in HIV-Positive Patients

Completed·OOttawa Heart Institute Research Corporation·Phase 4·NCT02234492·35 enrolled

A Study to Assess the Effect of AZD0780 on the Pharmacokinetics of Rosuvastatin.

Completed· AstraZeneca logo

AstraZeneca·Phase 1·NCT05787002·16 enrolled

A Study to Assess the Effects of BPN14770 on Rosuvastatin

Completed· Shionogi logo

Shionogi·Phase 1·NCT07011992·12 enrolled

Assess the Pharmacokinetics of Rosuvastatin and Simvastatin When Administered Alone or in Combination With Fostamatinib

Completed· AstraZeneca logo

AstraZeneca·Phase 1·NCT01725230·42 enrolled

A Phase I, Open-label, Crossover Study Comparing the Relative Bioavailability of a Fixed-Dose Combination of Laroprovstat/Rosuvastatin vs Their Single Therapy Products in Healthy Adults

Not yet recruiting· AstraZeneca logo

AstraZeneca·Phase 1·NCT07316608·44 enrolled

Statin and Atheroma Vulnerability Evaluation

Completed·SSeung-Jung Park·Phase 4·NCT00997880·312 enrolled

Study in Taiwanese Subjects Identified as CYP2C19 Poor and Extensive Metabolizers Receiving Rosuvastatin

Completed· AstraZeneca logo

AstraZeneca·Phase 1·NCT00766025·50 enrolled

A Study Measuring Effects on Intima Media Thickness: An Evaluation of Rosuvastatin 40 mg (METEOR)

Completed· AstraZeneca logo

AstraZeneca·Phase 3·NCT00225589·840 enrolled

A Study to Assess the Safety, Tolerability, Pharmacokinetics, and Pharmacodynamics of AZD4144 as Well as the Impact of AZD4144 on the Pharmacokinetics of Rosuvastatin and Furosemide in Healthy Participants

Completed· AstraZeneca logo

AstraZeneca·Phase 1·NCT06491550·91 enrolled

Rosuvastatin Calcium Bioequivalence Study - Fast

Completed· GSK logo

GSK·Phase 1·NCT01711749·60 enrolled

Rosuvastatin Interethnic PK Study

Terminated·UUniversity of California, San Francisco·Phase 1·NCT02215174·21 enrolled

Interaction18 trials

The Pharmacokinetic Drug-drug Interaction and Safety of Telmisartan/Amlodipine and Rosuvastatin in Healthy Male Volunteers

Completed·YYuhan Corporation·Phase 1·NCT02233218·60 enrolled

A Drug Drug Interaction (DDI) Study of Selpercatinib (LY3527723) and Rosuvastatin in Healthy Participants

Completed· Eli Lilly logo

Eli Lilly·Phase 1·NCT05906836·28 enrolled

Drug-Drug Interaction Study of Rucaparib, Rosuvastatin and Oral Contraceptives

Completed·Ppharmaand GmbH·Phase 1·NCT03954366·36 enrolled

Show 15 more trials

Drug-Drug Interaction Study Between EDP-235, Midazolam, Caffeine and Rosuvastatin in Healthy Subjects

Completed·EEnanta Pharmaceuticals, Inc·Phase 1·NCT05594615·24 enrolled

Study to Evaluate the Drug-drug Interaction of JMKX001899 in Healthy Subjects

Not yet recruiting·JJemincare·Phase 1·NCT06348290·72 enrolled

A Drug-Drug Interaction Study Between GDC-0853 and Midazolam, Itraconazole, Rosuvastatin, and Simvastatin

Completed· Roche logo

Roche·Phase 1·NCT03174041·63 enrolled

Drug-drug Interaction Between Digoxin, Furosemide, Metformin, and Rosuvastatin

Completed· Boehringer Ingelheim logo

Boehringer Ingelheim·Phase 1·NCT02231931·24 enrolled

Drug-drug Interaction Study of Ganaplacide and Lumefantrine With Midazolam, Repaglinide, Dextromethorphan, Metformin, Rosuvastatin and Dolutegravir

Completed· Novartis logo

Novartis·Phase 1·NCT05236530·48 enrolled

A Study to Investigate the Interaction of GSK1292263 With Rosuvastatin and Simvastatin in Healthy Subjects

Completed· GSK logo

GSK·Phase 1·NCT01101568·28 enrolled

A Phase 1 Study to Evaluate the Drug-Drug Interaction Potential Between ALG-055009 and Statin Therapy(Ies)

Completed·AAligos Therapeutics·Phase 1·NCT06191991·14 enrolled

Drug Interaction Study of MGL-3196 With Rosuvastatin and Simvastatin

Completed· Madrigal Pharmaceuticals logo

Madrigal Pharmaceuticals·Phase 1·NCT02542969·25 enrolled

Drug Interaction Statin

Completed· Bristol-Myers Squibb logo

Bristol-Myers Squibb·Phase 1·NCT02089061·26 enrolled

A Two-part Study to Investigate the Interaction and Pharmacokinetics of GSK2586184

Completed· GSK logo

GSK·Phase 1·NCT01953835·37 enrolled

Evaluating a Pharmacokinetic Drug Interaction Between Amlodipine/Losartan and Rosuvastatin

Unknown status· Hanmi Pharmaceutical Company Limited logo

Hanmi Pharmaceutical Company Limited·Phase 1·NCT02140489·30 enrolled

A Drug Interaction Study of KW-6356 With Midazolam, Caffeine, or Rosuvastatin

Completed· Kyowa Kirin Co., Ltd. logo

Kyowa Kirin Co., Ltd.·Phase 1·NCT03970798·50 enrolled

Drug-durg Interaction of Leritrelvir(RAY1216) With Midazolam, Omeprazole, Rosuvastatin, Verapamil, and Rifampin

Completed·GGuangdong Raynovent Biotech Co., Ltd·Phase 1·NCT06031454·56 enrolled

TMC435-TiDP16-C108 - A Study in Healthy Volunteers Investigating the Pharmacokinetic Interaction Between TMC435 and Digoxin and Between TMC435 and Rosuvastatin

Completed· Tibotec Pharmaceuticals, Ireland logo

Tibotec Pharmaceuticals, Ireland·Phase 1·NCT01288742·33 enrolled

Voxelotor CYP and Transporter Cocktail Interaction Study

Completed· Pfizer logo

Pfizer·Phase 1·NCT05981365·44 enrolled

Hypercholesterolemia9 trials

A Study to Compare Rosuvastatin/Ezetimibe and Rosuvastatin in Patients With Diabetes Mellitus and Hypercholesterolemia

Completed·YYuhan Corporation·Phase 4·NCT03217409·85 enrolled

Usability Study of the Commercial Auto-injector Device and the New Auto-injector Device (SYDNEY) in Patients With High or Very High CV Risk With Hypercholesterolemia Not Adequately Controlled With Their Lipid-Modifying Therapy

Completed· Sanofi logo

Sanofi·Phase 3·NCT03415178·69 enrolled

Mercury II - Compare the Efficacy and Safety of Lipid Lowering Agents Atorvastatin and Simvastatin With Rosuvastatin in High Risk Subjects With Type IIa and IIb Hypercholesterolemia

Completed· AstraZeneca logo

AstraZeneca·Phase 3·NCT00654407·4,875 enrolled

Show 6 more trials

A Clinical Trial to Assess the Long Term Safety and Tolerability of MK-0653H in Japanese Participants With Hypercholesterolemia (MK-0653H-833)

Completed·OOrganon and Co·Phase 3·NCT02748057·135 enrolled

Switching to Rosuvastatin Versus Adding Ezetimibe to Atorvastatin Versus Doubling the Dose of Atorvastatin in Patients With Hypercholesterolemia and Risk Factors (P03708)

Terminated·OOrganon and Co·Phase 4·NCT00651378·87 enrolled

Compare the Efficacy of Rosuvastatin to Atorvastatin in High Risk Patients With Hypercholesterolemia

Completed· AstraZeneca logo

AstraZeneca·Phase 3·NCT00683618·934 enrolled

The Efficacy and Safety of Combination Therapy of Rosuvastatin and Ezetimibe and Rosuvastatin Monotherapy in Patients With Primary Hypercholesterolemia

Completed·SShin Poong Pharmaceutical Co. Ltd.·Phase 3·NCT03288038·382 enrolled

A Study to Evaluate the Efficacy and Safety of Rosuvastatin in Hypercholesterolemia.

Unknown status·PPin Siang Medical Biotechnology Co., Ltd.·N/A·NCT01982461·40 enrolled

A Clinical Trial to Compare the Efficacy and Safety of a Combination Therapy of Ezetimibe and Rosuvastatin Versus Monotherapy of Rosuvastatin in Hypercholesterolemia Patients (I-ROSETTE Study)

Completed· IlDong Pharmaceutical Co Ltd logo

IlDong Pharmaceutical Co Ltd·Phase 3·NCT02749994·396 enrolled

Atorvastatin9 trials

PULSAR - A Prospective Study to Evaluate the Utility of Low Doses of the Statins Atorvastatin and Rosuvastatin.

Completed· AstraZeneca logo

AstraZeneca·Phase 3·NCT00329173·1,000 enrolled

STELLAR-Rosuvastatin vs. Atorvastatin, Pravastatin, Simvastatin Across Dose Ranges

Completed· AstraZeneca logo

AstraZeneca·Phase 3·NCT00654537·5,625 enrolled

A Drug-Drug Interaction (DDI) Study of HDM1002 With Repaglinide, Atorvastatin, Digoxin and Rosuvastatin in Healthy Subjects and Overweight Subjects.

Not yet recruiting·HHangzhou Zhongmei Huadong Pharmaceutical Co., Ltd.·Phase 1·NCT06601517·30 enrolled

Show 6 more trials

Polaris - Crestor 40 mg vs Atorvastatin 80 mg for 26 Weeks

Completed· AstraZeneca logo

AstraZeneca·Phase 3·NCT00653588

Drug-Drug Interaction Study of Vadadustat With Rosuvastatin, Sulfasalazine, Pravastatin, Atorvastatin and Simvastatin

Completed·AAkebia Therapeutics·Phase 1·NCT03801733·134 enrolled

A Study to Investigate the Effect of AZD5004 on Rosuvastatin, Atorvastatin, Simvastatin, Repaglinide and the Effect of Erythromycin on AZD5004 in Healthy Participants

Completed· AstraZeneca logo

AstraZeneca·Phase 1·NCT06948747·49 enrolled

A Drug Interaction Study Between Simvastatin, Atorvastatin, Rosuvastatin, and GSK2248761 in Healthy Subjects.

Completed· GSK logo

GSK·Phase 1·NCT01138072·14 enrolled

ECC5004 DDI Study With Atorvastatin, Rosuvastatin, Digoxin and Midazolam in Healthy Participants

Completed·EEccogene·Phase 1·NCT06293742·48 enrolled

A Drug-drug Interaction Study Evaluating the PK Effects of Obicetrapib on Atorvastatin and Rosuvastatin

Completed·NNewAmsterdam Pharma·Phase 1·NCT06081166·74 enrolled

Hypercholesterolaemia5 trials

Treatment of Hypercholesterolaemia in Hispanic Subjects (STARSHIP)

Completed· AstraZeneca logo

AstraZeneca·Phase 3·NCT00653965·3,000 enrolled

Treatment of Hypercholesterolaemia in South Asian Subjects (IRIS)

Completed· AstraZeneca logo

AstraZeneca·Phase 3·NCT00654225·2,340 enrolled

Study of Asian Patients With Hypercholesterolaemia in the UK - Rosuvastatin 5mg Versus Atorvastatin 10mg

Terminated· AstraZeneca logo

AstraZeneca·Phase 4·NCT00427960·55 enrolled

Show 2 more trials

Rosuvastatin Versus Atorvastatin in the Treatment of Hypercholesterolaemia in African American Subjects(ARIES)

Completed· AstraZeneca logo

AstraZeneca·Phase 3·NCT00653744·1,700 enrolled

An Study to Evaluate Rosuvastatin in Children and Adolescents With Familial Hypercholesterolaemia

Completed· AstraZeneca logo

AstraZeneca·Phase 3·NCT01078675·315 enrolled

91 more indications

Metformin5 trials

Influence of Fedratinib on the Pharmacokinetics of the Transporter Probe Substrates Digoxin, Rosuvastatin, and Metformin

Completed· Bristol-Myers Squibb logo

Bristol-Myers Squibb·Phase 1·NCT04231435·24 enrolled

DDI (Effect of Metformin and Furosemide on Rosuvastatin PK)

Completed· Boehringer Ingelheim logo

Boehringer Ingelheim·Phase 1·NCT02574845·18 enrolled

A Clinical Study of Calderasib (MK-1084) With Rosuvastatin and Metformin in Healthy People (MK-1084-016)

Completed· Merck & Co. logo

Merck & Co.·Phase 1·NCT07222098·16 enrolled

Show 2 more trials

A Study to Assess the Effect of Povorcitinib on Digoxin, Rosuvastatin, and Metformin Pharmacokinetics and the Effect of Probenecid on Povorcitinib Pharmacokinetics When Administered Orally to Healthy Adult Participants

Completed· Incyte logo

Incyte·Phase 1·NCT06416800·71 enrolled

A Study to Assess the Effects of Savolitinib on the Pharmacokinetics of Digoxin, Rosuvastatin, Metformin, and Furosemide in Healthy Male Subjects

Completed· AstraZeneca logo

AstraZeneca·Phase 1·NCT05768360·6 enrolled

Breast Cancer4 trials

Drug-drug Interaction Study Using Rosuvastatin as a Breast Cancer Resistant Protein (Efflux Transporter), Organic Anion-transporting Polypeptide (OATP)1B1, and OATP1B3 (Uptake Transporters) Probe Substrate

Completed· Bayer logo

Bayer·Phase 1·NCT02671097·30 enrolled

Identification and Validation of Biomarkers for Breast Cancer Resistance Protein (BCRP)

Completed·UUniversity of California, San Francisco·Phase 1·NCT04542382·11 enrolled

Rosuvastatin to Lower Circulating Tissue Factor Bearing Microparticles in Metastatic Breast Cancer

Completed·—·Phase 2·NCT01299038·20 enrolled

Show 1 more trial

Rosuvastatin in Treating Women With Cardiovascular Complications Who Are Undergoing Chemotherapy For Breast Cancer

Terminated·WWake Forest University Health Sciences·Phase 1·NCT01051401·5 enrolled

Heart Failure3 trials

Comparison of Lipophilic Versus Hydrophilic Statins on Patients With Heart Failure

Completed·—·Phase 4·NCT03255044·85 enrolled

Dutch Sub Study: Controlled Rosuvastatin Multinational Study in Heart Failure (CORONA). PET Sub Study

Completed· AstraZeneca logo

AstraZeneca·Phase 3·NCT00228514·40 enrolled

Impact of Rosuvastatin on Endothelial Function and Inflammation in Patients With Chronic Heart Failure

Completed·UUniversity of Leipzig·Phase 2·NCT00176332·40 enrolled

Coronary Artery Disease3 trials

Pharmacodynamic Comparison of Rosuvastatin Versus Atorvastatin on Platelet Reactivity in Patients With Coronary Artery Disease on Dual Antiplatelet Therapy With New P2Y12 Inhibitors (Trial gRANADa)

Unknown status·UUniversity of Roma La Sapienza·Phase 4·NCT02030054·150 enrolled

Peking and Rotterdam on Mission to Reduce Coronary Artery Disease

Unknown status·PPeking University Third Hospital·N/A·NCT01653119·1,000 enrolled

Effect of Alirocumab(Proprotein Convertase Subtilisin/Kexin type9 Inhibitor) and Rosuvastatin or Rosuvastatin Alone on Lipid Core Plaques in Coronary Artery Disease Evaluated by Near-infrared Spectroscopy Intravascular Ultrasound

Unknown status·KKobe University·Phase 4·NCT03529253·30 enrolled

Dyslipidaemia3 trials

A Study to Investigate the Effect of AZD0780 Tablets in Combination With Rosuvastatin Tablets on Low Density Lipoprotein Cholesterol Levels (LDL-C) in Adult Participants With Dyslipidaemia

Recruiting· AstraZeneca logo

AstraZeneca·Phase 2·NCT07218900·76 enrolled

TA-8995: Its Use in Patients With Mild Dyslipidaemia (TULIP)

Completed·XXention Ltd·Phase 2·NCT01970215·364 enrolled

A Study to Evaluate the Efficacy, Safety, and Pharmacokinetics of AZD0780 in Participants With Dyslipidaemia

Recruiting· AstraZeneca logo

AstraZeneca·Phase 2/3·NCT06834932·360 enrolled

Clinical Trial3 trials

Clinical Trial to Compare the Pharmacokinetics of DP-R208

Completed·AAlvogen Korea·Phase 1·NCT02707224·40 enrolled

Clinical Trial of YH14755 in Subjects With Dyslipidemia and Type II Diabetes

Completed·YYuhan Corporation·Phase 3·NCT02586129·249 enrolled

A Clinical Trial of HRS-1301 on the Pharmacokinetics of Rosuvastatin Calcium Tablets in Healthy Subjects

Completed·SShandong Suncadia Medicine Co., Ltd.·Phase 1·NCT07097831·16 enrolled

Acute Coronary Syndrome2 trials

Exploring Efficacy of Intensive Rosuvastatin Treatment Peri-PCI in Chinese Patients With Non ST-segment Elevated Acute Coronary Syndrome(NSTE-ACS)

Unknown status·SShanghai Zhongshan Hospital·Phase 4·NCT02284503·1,350 enrolled

Comparison of Rosuvastatin and Atorvastatin in Patients With Acute Coronary Syndrome

Completed·QQueen's University·Phase 4·NCT00665834·18 enrolled

Cholesterol2 trials

Study of High Density Lipoprotein Cholesterol (HDL-C)-Raising Mechanism of Rosuvastatin (CRESTOR™) by Quantifying the Key Steps of Reverse Cholesterol Transport (RCT)

Completed· AstraZeneca logo

AstraZeneca·Phase 3·NCT00240266·15 enrolled

KF2019#1-trial: Effects of a Thrombocyte Inhibitor on a Cholesterol-lowering Drug

Unknown status·HHelsinki University Central Hospital·Phase 1·NCT05373277·10 enrolled

Statins2 trials

Effects of Inclisiran Combined With Statins on the Morphology of Coronary Vulnerable Plaques

Recruiting·NNanjing First Hospital, Nanjing Medical University·Phase 4·NCT06338293·40 enrolled

Statins to Prevent Cancer Associated Blood Clots

Not yet recruiting·—·Phase 4·NCT07303816·4,000 enrolled

Treatment2 trials

Rosuvastatin Pre-Treatment Influences the Risk of Coronary Intervention Study

Unknown status·—·Phase 3·NCT01378715·400 enrolled

Study of Alirocumab (REGN727/SAR236553) added-on to Rosuvastatin Versus Other Lipid Modifying Treatments (LMT) (ODYSSEY OPTIONS II)

Completed· Regeneron logo

Regeneron·Phase 3·NCT01730053·305 enrolled

Tics2 trials

A Study to Compare the Pharmacokinetics of DP-R207 in Comparison to Each Component Administered Alone

Completed·AAlvogen Korea·Phase 1·NCT02730689·66 enrolled

Evaluate the Effect of Vimseltinib on the Pharmacokinetics of a BCRP and OATP1B1 Substrate

Completed·DDeciphera Pharmaceuticals, LLC·Phase 1·NCT07158398·20 enrolled

Type 2 Diabetes2 trials

Dapagliflozin and Cholesterol Metabolism in Type 2 Diabetes (DM2)

Completed·AAmsterdam UMC, location VUmc·Phase 4·NCT03074630·12 enrolled

LIpid Lowering With Highly Potent Statins in Hyperlipidaemia With Type 2 Diabetes patiENts

Completed·LListen Trial Group·N/A·NCT01544309·1,049 enrolled

Acute Kidney Injury2 trials

Rosuvastatin Prevent Contrast Induced Acute Kidney Injury in Patients With Diabetes

Completed·SShenyang Northern Hospital·Phase 4·NCT00786136·2,998 enrolled

Atorvastatin Versus Rosuvastatin on Contrast Induced Acute Kidney Injury (PRATO-ACS 2)

Completed·CCentro Cardiopatici Toscani·Phase 4·NCT01870804·760 enrolled

Efficacy and Safety2 trials

Evaluation of the Efficacy and Safety of Rosuvastatin 5 mg Versus Pravastatin 40 mg and Atorvastatin 10 mg in Type IIa and IIb Hypercholesterolaemic Patients

Completed· AstraZeneca logo

AstraZeneca·Phase 4·NCT00631189·668 enrolled

Efficacy and Safety of a Generic Rosuvastatin in a Real-world Setting

Completed·HHikma Pharmaceuticals LLC··NCT03516955·317 enrolled

Cardiovascular Events2 trials

A Study of Bempedoic Acid/Ezetimibe/High-intensity Statin in Patients Without Cardiovascular Events

Not yet recruiting· Daiichi Sankyo logo

Daiichi Sankyo·Phase 3·NCT07474649·103 enrolled

Effect of RVX000222 on Time to Major Adverse Cardiovascular Events in High-Risk T2DM Subjects With CAD

Completed·RResverlogix Corp·Phase 3·NCT02586155·2,425 enrolled

Hyperlipidemia2 trials

Efficacy and Safety Study of YH16410 Versus Rosuvastatin and Telmisartan Monotherapies in Patients With Hypertension and Hyperlipidemia

Completed·YYuhan Corporation·Phase 3·NCT01914432·210 enrolled

A Comparative Study of Rosuvastatin and Atorvastatin in Patients With Hyperlipidemia

Unknown status·—·Phase 2/3·NCT02979704·90 enrolled

Sepsis2 trials

Statins for Acutely Injured Lungs From Sepsis

Terminated·NNational Heart, Lung, and Blood Institute (NHLBI)·Phase 3·NCT00979121·745 enrolled

Effect of Rosuvastatin in Abdominal Sepsis

Unknown status·UUniversidad Autonoma de San Luis Potosí·Phase 2·NCT00357123·60 enrolled

Preeclampsia2 trials

Rosuvastatin in Order to Induce Preeclampsia Resolution in Severe PET up to 48 Hours Following Delivery

Unknown status·SSoroka University Medical Center·Phase 1/2·NCT02314286·100 enrolled

Effect of Rosuvastatin on the Clinical Features of Preeclampsia

Unknown status·—·Phase 2·NCT04303806·80 enrolled

Metabolic Syndrome2 trials

ROMEO (Rosuvastatin in Metabolic syndrOme)

Completed· AstraZeneca logo

AstraZeneca·Phase 4·NCT00395486·258 enrolled

A Study to Investigate the Effect of Rosuvastatin (CRESTOR®) on High Density Lipoprotein Kinetics in Patients With the Metabolic Syndrome

Completed· AstraZeneca logo

AstraZeneca·Phase 3·NCT00240305·15 enrolled

Efficacy2 trials

OLE Study to Evaluate Safety / Efficacy of ZD4522

Completed· AstraZeneca logo

AstraZeneca·Phase 3·NCT00654303·3,500 enrolled

Comparative Efficacy Evaluation of Lipids When Treated With Niaspan & Statin or Other Lipid-Modifying Therapies-COMPELL

Completed·KKos Pharmaceuticals·Phase 4·NCT00079638·300 enrolled

Mixed Dyslipidemia2 trials

Phase III Study of Rosuvastatin and Fenofibrate Versus Rosuvastatin in Mixed Dyslipidemia

Completed· IlDong Pharmaceutical Co Ltd logo

IlDong Pharmaceutical Co Ltd·Phase 3·NCT02262143·362 enrolled

A Year 2, Safety Extension Study of the Combination of ABT-335 and Statin Therapy for Subjects With Mixed Dyslipidemia

Completed·AAbbott·Phase 3·NCT00491530·310 enrolled

ART2 trials

A Study of LY4065967 in Healthy Japanese Participants

Completed· Eli Lilly logo

Eli Lilly·Phase 1·NCT06594159·59 enrolled

A Study of Lazertinib (JNJ-73841937) in Healthy Participants

Completed· Johnson & Johnson logo

Johnson & Johnson·Phase 1·NCT05076877·20 enrolled

Intracerebral Hemorrhage2 trials

Effect of Rosuvastatin in Intracerebral Hemorrhage

Completed·UUniversidad Autonoma de San Luis Potosí·Phase 2·NCT00364559·75 enrolled

Statins in Patients With Spontaneous Intracerebral Hemorrhage

Completed·PPomeranian Medical University Szczecin·N/A·NCT06094244·153 enrolled

Diabetes Mellitus2 trials

The Impact of Rosuvastatin on the Density Score of Coronary Artery Calcification in CAD Patients With Diabetes Mellitus

Unknown status·SSir Run Run Shaw Hospital·Phase 4·NCT02418884·122 enrolled

Efficacy and Safety of Berlim 25/10 Association in the Treatment of Type II Diabetes Mellitus and Dyslipidemia

Unknown status·EEMS·Phase 3·NCT04603508·240 enrolled

Chronic Periodontitis2 trials

Locally Delivered Metformin & Rosuvastatin for Treatment of Intrabony Defects in Chronic Periodontitis

Completed·GGovernment Dental College and Research Institute, Bangalore·Phase 2/3·NCT03204058·90 enrolled

Efficacy of Locally Delivred 1.2% Rosuvastatin Gel in Chronic Periodontitis

Completed·GGovernment Dental College and Research Institute, Bangalore·Phase 2/3·NCT02283515·65 enrolled

Coronary Atherosclerosis2 trials

PsA T2T Statin Trial on Carotid and Coronary Atherosclerosis

Withdrawn·—·N/A·NCT04176978

Different Doses of Rosuvastatin Therapy on Regression of Critical Coronary Atherosclerosis in ACS Patients

Unknown status·—·N/A·NCT02420899·100 enrolled

Carotid Artery Atheroma1 trial

Progression of Carotid Artery Atheroma in Moderately Hypercholesterolemic Subjects

Completed· AstraZeneca logo

AstraZeneca·Phase 3·NCT00654394·200 enrolled

Overweight1 trial

A Study to Learn How the Study Medicine Danuglipron is Taken Up Into the Blood and If Danuglipron Changes How the Body Processes Other Study Medicines (Atorvastatin and Rosuvastatin) in Healthy Adults Who Are Overweight or Obese

Completed· Pfizer logo

Pfizer·Phase 1·NCT06567327·82 enrolled

Portal Hypertension1 trial

Propranolol, Carvedilol and Rosuvastatin in the Prevention of Variceal Bleeding in Cirrhotic Portal Hypertension

Unknown status·UUniversidade Federal do Rio de Janeiro·Phase 2/3·NCT03720067·80 enrolled

Elderly1 trial

A Clinical Study to Evaluate PK, PD, and PG of Rosuvastatin in the Elderly

Completed·SSeoul National University Hospital·Phase 1·NCT03715101·20 enrolled

Chronic Kidney Disease1 trial

30 Week Study of the Combination of ABT-335 and Rosuvastatin Compared to Rosuvastatin Monotherapy for Subjects With Dyslipidemia and Stage 3 Chronic Kidney Disease

Completed· AstraZeneca logo

AstraZeneca·Phase 3·NCT00680017·280 enrolled

Effect of Drug1 trial

Study to Learn the Effect of Drug BAY1817080 on the Way the Body Absorbs, Distributes and Excretes Another Drug Rosuvastatin in Healthy Adult Participants

Completed· Bayer logo

Bayer·Phase 1·NCT04252300·14 enrolled

Cardiovascular1 trial

Depression and Cardiovascular Risk Markers: Effects of Rosuvastatin Therapy

Withdrawn·UUniversity Hospital, Akershus·Phase 2·NCT00951132

Cirrhosis1 trial

Liver Cirrhosis Network Rosuvastatin Efficacy and Safety for Cirrhosis in the United States

Recruiting·NNational Institute of Diabetes and Digestive and Kidney Diseases (NIDDK)·Phase 2·NCT05832229·256 enrolled

Ischemic stroke1 trial

The Effects of Very Early Use of Rosuvastatin in Preventing Recurrence of Ischemic Stroke

Terminated·SSeverance Hospital·Phase 3·NCT01364220·318 enrolled

Homeostasis1 trial

The Statins on Glucose Homeostasis in Subjects With Impaired Fasting Glucose

Unknown status·TTaipei Veterans General Hospital, Taiwan·Phase 4·NCT01816997·160 enrolled

Valve Surgery1 trial

A Trial to Evaluate the Effect of Rosuvastatin on Inflammation in Patients Undergoing Isolated Cardiac Valve Surgery

Completed·MMcGill University Health Centre/Research Institute of the McGill University Health Centre·Phase 3·NCT01425398·170 enrolled

Magnetic Resonance Imaging1 trial

Resuvastatin Treatment for Symptomatic Middle Cerebral Artery Stenosis Based on High-resolution Magnetic Resonance Imaging

Completed·—·Phase 4·NCT02041117·162 enrolled

Endothelial Dysfunction1 trial

Short Term Statin Treatment and Endothelial Dysfunction Due to Ischemia and Reperfusion Injury

Completed·RRadboud University Medical Center·Phase 4·NCT00987974·48 enrolled

Endometrial Carcinoma1 trial

Megestrol Acetate Plus Rosuvastatin in Young Women With Early Endometrial Carcinoma

Completed·FFudan University·Phase 2·NCT04491643·48 enrolled

Renal Impairment1 trial

Safety Study to Evaluate the Effects of Mild and Moderate Renal Impairment on the Pharmacokinetics of ABT-335 and Rosuvastatin When Administered Concomitantly

Completed· AstraZeneca logo

AstraZeneca·Phase 1·NCT00585143·37 enrolled

Nephropathy1 trial

A Randomized Trial of Rosuvastatin in Elective Angioplasty to Prevent Contrast-induced Nephropathy (CLEAR-CIN).

Completed·UUniversity of Sao Paulo·Phase 4·NCT02737319·493 enrolled

Imaging1 trial

CRESTOR Athero Imaging Head to Head IVUS Study

Completed· AstraZeneca logo

AstraZeneca·Phase 3·NCT00620542·2,333 enrolled

Rheumatoid Arthritis1 trial

Rosuvastatin in Rheumatoid Arthritis (RORA)

Completed·UUniversity of Dundee·Phase 2/3·NCT00679510·50 enrolled

Drug Interactions1 trial

CYP2B6 Genetics and Drug Interactions in Healthy Volunteers

Completed·IIndiana University·Phase 4·NCT02401256·70 enrolled

Prevention1 trial

EARly Prevention of aTHeroma Progression

Terminated·CCHEOL WHAN LEE, M.D., Ph.D·Phase 4·NCT02105623·111 enrolled

Necrosis1 trial

Rosuvastatin in Preventing Myonecrosis in Elective Percutaneous Coronary Interventions (PCIs)

Completed·UUniversity of Roma La Sapienza·Phase 3·NCT01007279·160 enrolled

Dyslipidemia1 trial

Characterization of Multi-dose RVX000222 in Combination With Statin Treatment in Dyslipidemia

Terminated·RResverlogix Corp·Phase 2·NCT01863225·13 enrolled

Chest pain1 trial

Women With Chest Pain and no Significant Coronary Artery Stenosis; A Study on Microvascular Resistance

Completed·OOslo University Hospital·Phase 4·NCT01582165·66 enrolled

Midazolam1 trial

A Study to Assess the Effect of AZD5462 on the Pharmacokinetics of Midazolam, Rosuvastatin and Digoxin

Completed· AstraZeneca logo

AstraZeneca·Phase 1·NCT05395117·32 enrolled

Adult1 trial

Study to Evaluate the Effect of Repotrectinib on the Drug Levels of Transporter and CYP P450 Probe Substrates in Healthy Adult Participants

Recruiting· Bristol-Myers Squibb logo

Bristol-Myers Squibb·Phase 1·NCT07223671·32 enrolled

Lip1 trial

Type III Dysbetalipoproteinemia

Completed· AstraZeneca logo

AstraZeneca·Phase 3·NCT00214604·30 enrolled

Chronic Obstructive Pulmonary Disease1 trial

Effect of Rosuvastatin Therapy in Patients With Stable Chronic Obstructive Pulmonary Disease

Completed·UUniversity Hospital, Akershus·Phase 2·NCT00929734·99 enrolled

Non-Small Cell Lung Cancer1 trial

Study to Assess the Effect of AZD9291 on the Blood Levels of Rosuvastatin, in Patients With EGFRm+ Non-small Cell Lung Cancer

Completed· AstraZeneca logo

AstraZeneca·Phase 1·NCT02317016·44 enrolled

Plaque1 trial

CT COMPARE: CT Coronary Angiography to Measure Plaque Reduction

Terminated·NNational Heart, Lung, and Blood Institute (NHLBI)·Phase 4·NCT02740699·79 enrolled

Single Dose1 trial

An Open-Label Study of the Effect of Bardoxolone Methyl on the Single Dose Pharmacokinetics of Digoxin and Rosuvastatin in Healthy Volunteers

Completed· Biogen logo

Biogen·Phase 1·NCT01598363·32 enrolled

Ischemia1 trial

Does Caffeine Reduce Rosuvastatin-Induced Protection Against Ischemia-Reperfusion Injury?

Completed·RRadboud University Medical Center·Phase 4·NCT00457652·24 enrolled

Methotrexate1 trial

A Study Investigating Interactions Between BMS-986322 and Rosuvastatin, Metformin and Methotrexate in Healthy Participants

Completed· Bristol-Myers Squibb logo

Bristol-Myers Squibb·Phase 1·NCT05615012·76 enrolled

Obesity1 trial

Study To Evaluate The Effect Of Two Steady State Doses of PF 06882961 On Rosuvastatin And Midazolam Pharmacokinetics In Otherwise Healthy Adult Participants With Obesity

Completed· Pfizer logo

Pfizer·Phase 1·NCT04621227·16 enrolled

Cardiac Surgery1 trial

Statin Therapy In Cardiac Surgery

Completed·UUniversity of Oxford·Phase 4·NCT01573143·1,922 enrolled

Friedreich ataxia1 trial

Rosuvastatin (Crestor) in Friedreich Ataxia

Completed·—·Phase 1·NCT02705547·12 enrolled

Transplant Recipient1 trial

The Rosuvastatin In TrAnsplant Recipients Study

Completed·UUniversity of Oslo School of Pharmacy·Phase 4·NCT01524601·20 enrolled

Optical Coherence Tomography1 trial

Evaluation of Statin-induced Lipid-rich Plaque Progression by Optical Coherence Tomography (OCT) Combined With Intravascular Ultrasound (IVUS)

Completed·HHarbin Medical University·Phase 4·NCT01023607·120 enrolled

Sexual Function1 trial

Statin Lowering Testosterone and Sexual Function

Completed·—·Phase 4·NCT02612714·151 enrolled

Pediatric1 trial

PLUTO: Pediatric Lipid-redUction Trial of rOsuvastatin

Completed· AstraZeneca logo

AstraZeneca·Phase 3·NCT00355615·173 enrolled

Hepatitis C1 trial

Rosuvastatin for Hepatitis C

Withdrawn·UUMC Utrecht·N/A·NCT00371579

Atherosclerotic Plaque1 trial

Effects of Crestor on Inflammation of Atherosclerotic Plaques

Completed· AstraZeneca logo

AstraZeneca·Phase 1·NCT00689416·74 enrolled

Renal artery stenosis1 trial

Compare Effects of Intensive Versus Conventional Lipid-lowering Therapy in Patients With Severe Atherosclerotic Renal Artery Stenosis Undergoing Stent Placement

Completed·—·Phase 2/3·NCT03521700·150 enrolled

Concentration1 trial

Clinical Study to Investigate the Effect of Macitentan on the Concentrations of Rosuvastatin in the Blood of Healthy Male Subjects

Completed· Johnson & Johnson logo

Johnson & Johnson·Phase 1·NCT03359291·20 enrolled

Major Adverse Cardiac Events1 trial

Primary Prevention of Major Adverse Cardiac Events (MACE) With Standard and Intensive Statin Treatment in Patients With Diabetes: Survival and Cardiovascular Event Assessments

Terminated·PPositive Trial Group·N/A·NCT01173939·10,000 enrolled

Endothelial Function1 trial

Rosuvastatin and Renal Endothelial Function

Completed·UUniversity of Erlangen-Nürnberg Medical School·Phase 2·NCT00160745·46 enrolled

Vascular Disease1 trial

SystemIc iNflammation and Microvascular diSease PreventIon in psoRiatic diseasE

Withdrawn·—·Phase 4·NCT04417114

Caffeine1 trial

Pharmacokinetic and Safety Study of Cenicriviroc and HMG-CoA Reductase Inhibitors, Caffeine and Digoxin

Completed·TTobira Therapeutics, Inc.·Phase 1·NCT02685462·36 enrolled

Percutaneous Coronary Intervention1 trial

Randomized Trial of Creatine-kinase Leak After Rosuvastatin At the Time of Percutaneous Coronary Intervention

Unknown status·KKleber Bomfim Araujo Martins·Phase 4·NCT01968577·528 enrolled

Observational Study1 trial

Assessment of the Efficacy of Rosuvastatin in Patient Groups With a Dissimilar Risk Profile in an Observational Study (HEROS)

Completed· AstraZeneca logo

AstraZeneca··NCT00660764

Atherosclerosis1 trial

Does Rosuvastatin Delay Progression of Atherosclerosis in HIV

Completed·BBayside Health·Phase 4·NCT01813357·84 enrolled

Systemic Lupus Erythematosus1 trial

A Trial of Rosuvastatin in Systemic Lupus Erythematosus

Completed·IImperial College London·Phase 2·NCT01170585·33 enrolled

Function1 trial

Exploratory Study of Coronary Flow Reserve Measurements, a Non-Invasive Method for Coronary Function Measurements

Completed· AstraZeneca logo

AstraZeneca·Phase 1·NCT00783042·80 enrolled

Hypertension1 trial

Clinical Study for Patients With Hypertension Associated With Dyslipidemia

Completed· Daewoong Pharmaceutical Co. LTD. logo

Daewoong Pharmaceutical Co. LTD.·Phase 3·NCT01764295·150 enrolled

Drug Transporter1 trial

A Drug-Drug Interaction Study to Evaluate Drug Transporter Interactions

Completed·BBioCryst Pharmaceuticals·Phase 1·NCT03136237·54 enrolled

Fidaxomicin1 trial

A Study to Assess the Effects of Multiple Doses of Fidaxomicin on a Single Dose of Rosuvastatin in Healthy Male Subjects

Completed· Astellas logo

Astellas·Phase 1·NCT02083627·25 enrolled

Diabetic Polyneuropathy1 trial

The Effect of Rosuvastatin in Diabetic Polyneuropathy: A Phase IIa Randomized Double-blind Placebo-controlled Study

Completed·AAlejandra Guillermina Miranda Diaz·Phase 2·NCT01622777·34 enrolled

Prostate Cancer1 trial

A Study to Evaluate the Effect of Multiple Doses of Enzalutamide on the Pharmacokinetics of Substrates of P-glycoprotein (Digoxin) and Breast Cancer Resistant Protein (Rosuvastatin) in Male Subjects With Prostate Cancer

Completed· Astellas logo

Astellas·Phase 1·NCT04094519·24 enrolled

Arteriovenous Fistula1 trial

Vascular Protective Effect of Rosuvastatin in Arteriovenous Fistula

Completed·NNational Cheng-Kung University Hospital·Phase 2·NCT01863914·60 enrolled

Cytokines1 trial

Rosuvastatin Impact on Ventricular Remodelling Lipids and Cytokines

Completed· AstraZeneca logo

AstraZeneca·Phase 3·NCT00240292·160 enrolled

Intravascular Ultrasound1 trial

A Study To Evaluate the Effect of Rosuvastatin On Intravascular Ultrasound-Derived Coronary Atheroma Burden (ASTEROID)

Completed· AstraZeneca logo

AstraZeneca·Phase 3·NCT00240318·450 enrolled

Heart Disease1 trial

Assessment of the Lipid Lowering Effect of Rosuvastatin Compared to Atorvastatin in Subjects With Coronary Heart Disease

Completed· AstraZeneca logo

AstraZeneca·Phase 4·NCT00235950·255 enrolled

Safety and Efficacy1 trial

A Multicenter Study Comparing the Safety and Efficacy of ABT-335 and Rosuvastatin Calcium Combination Therapy to Monotherapy in Subjects With Dyslipidemia

Completed· AstraZeneca logo

AstraZeneca·Phase 3·NCT00463606·760 enrolled

Metabolic Disease1 trial

Statin Monotherapy for Treatment of Endocrine Metabolic Disease Risk

Unknown status·—·Phase 2·NCT03113994·8 enrolled

Cardiovascular Disease1 trial

Effects of Statin for Elderly Patients With Atherosclerotic Cardiovascular Disease

Completed·KKorea University Anam Hospital·Phase 4·NCT04826354·582 enrolled

Unspecified4 trials

DISCOVERY Asia - Crestor in Type IIa and IIb Hypercholesteremia

Completed· AstraZeneca logo

AstraZeneca·Phase 3·NCT00241488·1,362 enrolled

DP-R212 Pharmacokinetic Study Phase I

Unknown status·AAlvogen Korea·Phase 1·NCT02814500·36 enrolled

DP-R212 Pharmacokinetic Study

Unknown status·AAlvogen Korea·Phase 1·NCT02789475·38 enrolled

Show 1 more trial

A Study of LY2484595 in Patients With High LDL-C or Low HDL-C

Completed· Eli Lilly logo

Eli Lilly·Phase 2·NCT01105975·398 enrolled

Regulatory

FDA Approval Timeline[5]

Aug 12, 2003

CRESTOR

NDA NDA021366

Dec 18, 2018

EZALLOR SPRINKLE

NDA NDA208647

Sources

References

[1]
ClinicalTrials.gov — 520 trial records for rosuvastatin. U.S. National Library of Medicine, National Institutes of Health.
[2]
MedlinePlus Drug Information — Crestor drug information. U.S. National Library of Medicine, National Institutes of Health.
[3]
ChEMBL — rosuvastatin compound record. European Bioinformatics Institute (EMBL-EBI).
[4]
Open Targets Platform — Drug–disease associations for rosuvastatin. EMBL-EBI & Wellcome Sanger Institute.
[5]
OpenFDA — FDA approval records (NDA NDA208647). U.S. Food & Drug Administration.
[6]
FDA Orange Book — Patent and exclusivity data for Crestor. U.S. Food & Drug Administration.
[7]
SEC EDGAR — AstraZeneca company filings. U.S. Securities and Exchange Commission.

Details

Drug Info

Quick Facts

Mechanism of Action: HMG-Coa Reductase Inhibitor[3]
Modality: Small molecule[3]
Highest Phase: Approved[1]
Company: AstraZeneca

Patent Landscape[6]

Patent Cliff

Feb 12, 2036

Earliest patent expiration — generic entry possible after this date

Patent #Expires

10413543Feb 12, 2036