VivoSeq
Neurology

Dystonia

17

Pipeline Programs↗

6

Active Trials↗

11

Companies Involved↗

Dystonia is an emerging landscape with 17 programs across 11 companies. The most active players are Bristol-Myers Squibb, Sun Pharmaceutical Industries, Inc., Vima Therapeutics. 2 therapies are approved with 3 more in late-stage development.

Intelligence

Pipeline Metrics

Competitive Density

46/100

Pipeline Velocity

6/100

Mech. Concentration

33/100

Completion Rate

92/100

Attrition Rate

5/100

Competition

Competitive Landscape

Bubble size = clinical trials

Approved
Phase 3
Phase 2
Phase 1
Preclinical

Key Players

Top Companies Companies ranked by the number of pipeline programs they run for this disease.

Bristol-Myers Squibb logo

Bristol-Myers Squibb

1 program

Phase 1Sun Pharmaceutical Industries, Inc. logo

Sun Pharmaceutical Industries, Inc.

1 program

Phase 2V

Vima Therapeutics

1 program

Phase 2UCB logo

UCB

1 program

Phase 2Teva logo

Teva

1 program

Phase 2Ipsen logo

Ipsen

1 program

Phase 3

Pipeline

Programs by Phase

Analysis

Trial Status

20

clinical trials

Completed11 · 55%
Recruiting5 · 25%
Unknown status2 · 10%
Terminated1 · 5%
Active, not recruiting1 · 5%

Clinical Trials

Trial Activity

20 trials

A Study to Evaluate the Efficacy, Safety, and Tolerability of VIM0423 in Individuals With Isolated Dystonia
Recruiting·VVima Therapeutics·Phase 2·NCT07304089·100 enrolled
Factors Determining the Efficacy of Botulinum Toxin for Arm Tremor in Dystonia
Recruiting·RRadboud University Medical Center·Phase 4·NCT06411028·60 enrolled
IncobotulinumtoxinA (Xeomin) to Treat Focal Hand Dystonia
Recruiting·—·Phase 3·NCT03977493·48 enrolled
Understanding Disorder-specific Neural Pathophysiology in Laryngeal Dystonia and Voice Tremor
Recruiting·MMassachusetts Eye and Ear Infirmary·Phase 1·NCT05216770·165 enrolled
Prospective Study of Deep Brain Stimulation With the VERCISE™ System for Treatment of Dystonia
Recruiting·BBoston Scientific Corporation·N/A·NCT02686125·300 enrolled
Deep Brain Stimulation Surgery for Treatment of Focal Hand Dystonia
Active, not recruiting·National Institute of Neurological Disorders and Stroke (NINDS)·Preclinical·NCT02911103·5 enrolled
Abobotulinum Toxin and Neubotulinum Toxin Injection in Cerivical Dystonia
Completed·Department of Medical Services Ministry of Public Health of Thailand·Phase 3·NCT03805152·52 enrolled
Outcome of Botulinum Toxin Treatment for Oromandibular Dystonia
Completed·FFondation Ophtalmologique Adolphe de Rothschild·N/A·NCT03363113·240 enrolled
Efficacy Trial of Zonisamide for Myoclonus Dystonia
Completed·AAssistance Publique - Hôpitaux de Paris·Phase 3·NCT01806805·24 enrolled
Incobotulinum Toxin A (Xeomin®) As A Treatment For Focal Task-Specific Dystonia Of The Musician's Hand
Completed·IIcahn School of Medicine at Mount Sinai·Phase 2·NCT02107261·21 enrolled
Quantifying Musical Performance After Treatment With Myobloc in Musician's Dystonia
Completed·—·Phase 4·NCT00208091·16 enrolled
Ampicillin for DYT-1 Dystonia Motor Symptoms
Completed·UUniversity of Florida·Phase 1·NCT01433757·2 enrolled
Neubotulinum Toxin Injection in Cerivical Dystonia
Completed·Department of Medical Services Ministry of Public Health of Thailand·Phase 3·NCT04582929·50 enrolled
Efficacy of Levetiracetam in Oromandibular and Cranial Dystonia
Completed·National Institute of Neurological Disorders and Stroke (NINDS)·Phase 2·NCT02199509·8 enrolled
Neuroimaging of Dystonia
Completed·UUniversity of Florida·N/A·NCT02046447·20 enrolled
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Data sources: ClinicalTrials.gov (NIH) · OpenFDA (FDA) · ChEMBL (EMBL-EBI) · Open Targets (EBI/Sanger) · MedlinePlus (NIH) · PubMed (NIH) · SEC EDGAR (SEC)