Botulinum Toxins

PreclinicalSmall molecule

YYale University

Botulinum Toxins is one of 16 small molecule programs targeting Dystonia. It is currently in Preclinical.

Indications

Total Trials

Active Trials

Competitors

Pipeline

Status by Indication[3][1]

Indication

DystoniaActive, not recruiting

Anal FissureActive, not recruiting

Randomised Controlled TrialUnknown status

DystoniaPreclinical

Active, not recruiting

Anal FissurePreclinical

Active, not recruiting

Randomised Controlled TrialPreclinical

Unknown status

Competition

Competitive Landscape

7 competitors in Anal Fissure

#DrugCompanyPhaseTrials

Golytely

Bayer

Approved

1 2

Isordil

AstraZeneca

Approved

—3

Chronulac

SSolvay Pharmaceuticals

Approved

1 4

Cardizem

BBausch Health Americas, Inc.

Phase 2

2 5

Rogaine

Pfizer

Preclinical

1 6

E-CEL UVEC

WWeill Medical College of Cornell University

Phase 1

1 7

Glyceryl - Trinitrate

PProcris Pharmaceuticals

Preclinical

2 8

Botulinum Toxins

YYale University

Preclinical

Ranked by pipeline maturity and clinical activity. Current drug highlighted in teal.

Clinical

Trials by Indication[1]

Botulinum Toxin2 trials

The Efficacy and Molecular Mechanism of Botulinum Toxin in the Reduction of Breast Reduction Mammoplasty Scar Formation

Completed·HHenry Ford Health System·Phase 2/3·NCT03887377·22 enrolled

Botulinum Toxin Injection in the Treatment of Open Abdomen

Unknown status·UUniversity of Oulu··NCT04283916·30 enrolled

Chronic Neck Pain1 trial

New Approaches in Evaluating Patients' Response to Botulinum Toxins in the Treatment of Chronic Neck Pain and Back Pain

Unknown status·VVA Connecticut Healthcare System·Phase 1·NCT02008136·60 enrolled

Randomised Controlled Trial1 trial

The Use of Botulinum Toxin in the Treatment of Itching From Hypertrophic Scar -- A Randomised Controlled Trial

Unknown status·KKaohsiung Veterans General Hospital.·N/A·NCT02168634·60 enrolled

Dystonia1 trial

Outcome of Botulinum Toxin Treatment for Oromandibular Dystonia

Completed·FFondation Ophtalmologique Adolphe de Rothschild··NCT03363113·240 enrolled

Breast Reconstruction1 trial

A Prospective Trial to Reduce Post-Operative Pain in Implant Based Breast Reconstruction

Terminated·YYale University·Phase 2·NCT02044302·2 enrolled

1 more indication

Anal fissure1 trial

Postero-lateral Internal Sphincterotomy vs Botulinum Toxin Injection in the Treatment of Chronic Anal Fissure

Unknown status·MMansoura University·N/A·NCT03920449·60 enrolled

Sources

References

[1]
ClinicalTrials.gov — 7 trial records for Botulinum Toxins. U.S. National Library of Medicine, National Institutes of Health.
[2]
ChEMBL — Botulinum Toxins compound record. European Bioinformatics Institute (EMBL-EBI).
[3]
Open Targets Platform — Drug–disease associations for Botulinum Toxins. EMBL-EBI & Wellcome Sanger Institute.
[4]
SEC EDGAR — Yale University company filings. U.S. Securities and Exchange Commission.

Details

Drug Info

Quick Facts

Modality: Small molecule[2]
Highest Phase: Preclinical[1]
Company: YYale University

Botulinum Toxins

Status by Indication[3][1]

Competitive Landscape

Trials by Indication[1]

Botulinum Toxin2 trials

Chronic Neck Pain1 trial

Randomised Controlled Trial1 trial

Dystonia1 trial

Breast Reconstruction1 trial

Anal fissure1 trial

References

Drug Info

Quick Facts

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