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Other/Laparoscopic Cholecystectomy

Laparoscopic Cholecystectomy

18

Pipeline Programs↗

27

Active Trials↗

4

Companies Involved↗

Laparoscopic Cholecystectomy is an emerging landscape with 18 programs across 4 companies. 5 programs are in Phase 3.

Intelligence

Pipeline Metrics

Competitive Density

52/100

Pipeline Velocity

43/100

Mech. Concentration

25/100

Completion Rate

95/100

Attrition Rate

3/100

Pipeline

Programs by Phase

Preclinical13

Magnesium Sulfate

Fresenius Kabi USA, LLC

Esketamine

Wim Janssens

Esketamine and Magnesium Sulfate

The Second People's Hospital of Huai'an

Bupevecaine

Mansoura University

Sevoflurane

AbbVie

Phase 1

No programs

Phase 2

No programs

Phase 35

Intraoperitoneal Local Anesthetic Administration

Rawalpindi Medical College

Bupivacaine and Dexmedetomidine

Kafrelsheikh University

IV Antibiotic

Minia University Hospital

Magnesium Sulfate 24 Hours

Instituto Materno Infantil Prof. Fernando Figueira

Bupivacaine and Fentanyl

Weill Medical College of Cornell University

Approved

No programs

Analysis

Trial Status

155

clinical trials

Completed93 · 60%

Unknown status30 · 19%

Not yet recruiting13 · 8%

Recruiting12 · 8%

Withdrawn3 · 2%

Terminated2 · 1%

Other2 · 1%

Clinical Trials

Trial Activity

155 trials

Effect of Subcostal Transversus Abdominis Plane Block on Analgesia, EEG Dynamics, and Burst Suppression in Laparoscopic Cholecystectomy

Recruiting·SSehit Prof. Dr. Ilhan Varank Sancaktepe Training and Research Hospital·N/A·NCT07818954·60 enrolled

Comparison of Mechanical Power in Pressure-Regulated Volume Control and Volume-Controlled Ventilation Modes During Laparoscopic Cholecystectomy

Recruiting·DDr Abdurrahman Yurtaslan Ankara Oncology Training and Research Hospital·Preclinical·NCT07670494·80 enrolled

Pain Relief Following Laparoscopic Cholecystectomy While Comparing Intra Abdominal Versus Sub Cutaneous Local Anesthetic Administration

Recruiting·RRawalpindi Medical College·Phase 4·NCT07409688·100 enrolled

EOIB for Laparoscopic Cholecystectomy

Recruiting·SSehit Prof. Dr. Ilhan Varank Sancaktepe Training and Research Hospital·N/A·NCT06656299·60 enrolled

Fentanyl vs. Remifentanil in Laparoscopic Cholecystectomy: Effects on Bowel Function and Pain

Recruiting·KKonya City Hospital·N/A·NCT07182097·106 enrolled

Comparative Efficacy of Intravenous Labetalol and Lignocaine in Mitigating Hemodynamic Responses to Laryngoscopy During Laparoscopic Cholecystectomy

Recruiting·—·N/A·NCT07192081·116 enrolled

Laparoscopic-Assisted Transversus Abdominus Plane Block Versus Intraperitoneal Irrigation of Local Anesthetic for Patients Undergoing Laparoscopic Cholecystectomy

Recruiting·RRoyal College of Surgeons, Ireland·Phase 1·NCT06714279·144 enrolled

The Role of Postoperative Antibiotics in Laparoscopic Cholecystectomy

Recruiting·MMinia University Hospital·Phase 4·NCT06607887·300 enrolled

External Oblique Intercostal Block in Laparoscopic Cholecystectomy

Recruiting·OOndokuz Mayıs University·N/A·NCT07164664·60 enrolled

Effect of Single Dose Intravenous Magnesium Sulfate on Postoperative Analgesic Consumption in Patients Undergoing Laparoscopic Cholecystectomy

Recruiting·TTata Main Hospital·Phase 4·NCT07328893·106 enrolled

Comparison Between Standard and Reduced Doses of Indocyanine Green in Fluorescence Cholangiography During Laparoscopic Cholecystectomy.

Recruiting·IInstituto de Investigación Biomédica de Salamanca·Phase 4·NCT07195331·122 enrolled

Efficacy and Safety of Cocktail of Ropivacaine for Local Infiltration Analgesia in Patients Undergoing Laparoscopic Cholecystectomy

Recruiting·SSichuan Provincial People's Hospital·N/A·NCT06819748·210 enrolled

Peritoneal Lavage Using Saline or Saline With Ondansetron for Pain Control After Laparoscopic Cholecystectomy

Active, not recruiting·IInstituto Mexicano del Seguro Social·Phase 4·NCT06632184·40 enrolled

Comparison of Perioperative Analgesia Nociception Index (ANI) Between Preoperative and Postoperative Ultrasound-guided Transversus Abdominis Plane Block(TAP Block) in Laparoscopic Cholecystectomy

Not yet recruiting·PPusan National University Yangsan Hospital·Preclinical·NCT07809009·120 enrolled

Analgesic Efficacy of Opioid-Free Anesthesia Protocol Combined With Ultrasound-Guided External Oblique Intercostal Plane Block for Laparoscopic Cholecystectomy: A Prospective Randomized Comparative Study

Not yet recruiting·AAssiut University·Preclinical·NCT07750769·70 enrolled

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Data sources: ClinicalTrials.gov (NIH) · OpenFDA (FDA) · ChEMBL (EMBL-EBI) · Open Targets (EBI/Sanger) · MedlinePlus (NIH) · PubMed (NIH) · SEC EDGAR (SEC)