VivoSeq
Other

Loss of Consciousness

6

Pipeline Programs↗

1

Active Trials↗

3

Companies Involved↗

Loss of consciousness is an early-stage landscape with 6 programs across 3 companies. The most active players are Pfizer's Upjohn has merged with Mylan to form Viatris Inc., Fresenius Kabi Oncology Ltd., Acacia Pharma Ltd. 1 therapy is approved.

Intelligence

Pipeline Metrics

Competitive Density

30/100

Pipeline Velocity

0/100

Mech. Concentration

60/100

Completion Rate

100/100

Attrition Rate

0/100

Competition

Competitive Landscape

Bubble size = clinical trials

Approved
Phase 3
Phase 2
Phase 1
Preclinical

Key Players

Top Companies Companies ranked by the number of pipeline programs they run for this disease.

P

Pfizer's Upjohn has merged with Mylan to form Viatris Inc.

1 program

ApprovedF

Fresenius Kabi Oncology Ltd.

1 program

PreclinicalA

Acacia Pharma Ltd

1 program

Preclinical

Pipeline

Programs by Phase

Analysis

Trial Status

9

clinical trials

Completed5 · 56%
Unknown status3 · 33%
Recruiting1 · 11%

Clinical Trials

Trial Activity

9 trials

Ciprofol EC50 for Inducing Loss of Consciousness in Elderly Patients
Recruiting·ZZhejiang Cancer Hospital·Phase 4·NCT06253078·150 enrolled
Remifentanil and Midazolam on Propofol for Loss of Consciousness
Completed·SSeverance Hospital·N/A·NCT02536690·120 enrolled
The Effects of Different Doses of Dexmedetomidine on Propofol Requirement for Loss of Consciousness Undergoing Bispectral Index: a Double-blinded, Placebo-controlled Trial
Completed·GGeneral Hospital of Ningxia Medical University·N/A·NCT02783846·73 enrolled
The Effects of Spinal Anesthesia on ED50 and BIS50 of Etomidate for the Loss of Consciousness
Completed·GGeneral Hospital of Ningxia Medical University·N/A·NCT03240055·54 enrolled
A Phase IV Study Investigating the Effects of Remifentanil Concentrations on Propofol Requirements for Loss of Consciousness, Response to Painful Stimuli, Bispectral Index and Associated Haemodynamic Changes
Completed·TThe University of Hong Kong·Phase 4·NCT02287181·100 enrolled
Propofol EC50 for Inducing Loss of Consciousness in General Combined Epidural Anesthesia
Completed·—·N/A·NCT05124704·60 enrolled
The Effect of the ALDH2 Gene Polymorphism on the Propofol Potency for Inducing Loss of Consciousness
Unknown status·SShanghai Zhongshan Hospital·N/A·NCT03762538·100 enrolled
The Effect of Remifentanil on ED95 of Remimazolam for Loss of Consciousness in Adult Patients
Unknown status·—·N/A·NCT05434494·80 enrolled
Remifentanil and Midazolam on Propofol for Loss of Consciousness in Elderly Patients
Unknown status·GGangnam Severance Hospital·N/A·NCT02818387·120 enrolled

Data sources: ClinicalTrials.gov (NIH) · OpenFDA (FDA) · ChEMBL (EMBL-EBI) · Open Targets (EBI/Sanger) · MedlinePlus (NIH) · PubMed (NIH) · SEC EDGAR (SEC)