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Other/Malnutrition

Malnutrition

15

Pipeline Programs↗

18

Active Trials↗

14

Companies Involved↗

Malnutrition is an emerging landscape with 15 programs across 14 companies. 2 programs are in Phase 3.

Intelligence

Pipeline Metrics

Competitive Density

48/100

Pipeline Velocity

32/100

Mech. Concentration

100/100

Completion Rate

76/100

Attrition Rate

15/100

Pipeline

Programs by Phase

Preclinical13

Dexamethasone

Aspen Global Incorporated

Zinc

American Regent, Inc.

Nandrolone Decanoate

McNeil Consumer & Specialty Pharmaceuticals, a Division of McNeil-PPC, Inc.

Sulfadoxine Pyrimethamine

Pfizer

Albendazole.

GSK

Phase 1

No programs

Phase 2

No programs

Phase 32

L-Citrulline

Asklepion Pharmaceuticals, LLC

Pneumococcal Conjugate Vaccine

Novartis

Approved

No programs

Analysis

Modality Breakdown

92%

Small molecule

12 of 13 classified programs — the dominant modality here.

Small molecule leads; the ring shows all 13 classified programs, each share of the total. Modality classified for 100% of 15 pipeline programs.

Analysis

Trial Status

62

clinical trials

Completed28 · 45%

Recruiting9 · 15%

Unknown status7 · 11%

Not yet recruiting5 · 8%

Withdrawn5 · 8%

Active, not recruiting4 · 6%

Other4 · 6%

Clinical Trials

Trial Activity

62 trials

A Mixed Methods Randomized Controlled Trial Testing a Two-way SMS Platform to Recognize and Prevent Wasting Among HIV-infected and HIV-exposed Uninfected Children in Kenya

Recruiting·UUniversity of Washington·Preclinical·NCT06842732·776 enrolled

PlAnt Vs Animal Based Oral Nutritional Supplements: Patients' Opinions and Nutritional Outcomes: A Multicenter Pilot Feasibility Study

Recruiting·RRadboud University Medical Center·Preclinical·NCT07399886·60 enrolled

STRIKE: Stunting and Targeting Reduction of Impaired Growth in Kids Effectively: A Community Engaged Comprehensive, Multi-Faceted Nutrition Quality Improvement Program

Recruiting·—·N/A·NCT07524907·158 enrolled

Implementation of Nutritional Treatment to Older Patients Discharged With the Liaison Team

Recruiting·HHerlev and Gentofte Hospital·Preclinical·NCT06706661·2,000 enrolled

Modified Dosage for Severe Acute Malnutrition

Recruiting·AAction Against Hunger USA·N/A·NCT06061484·2,400 enrolled

Pancrelipase With Nutritional Supplement in Patients at Risk of Malnutrition (EFFORT-ENZO)

Recruiting·—·N/A·NCT06826105·20 enrolled

Azithromycin as Adjunctive Treatment for Uncomplicated Severe Acute Malnutrition

Recruiting·UUniversity of California, San Francisco·Phase 4·NCT06010719·3,000 enrolled

Milk Fat Globule Membrane-Enhanced RUTF for Children With Severe Acute Malnutrition

Recruiting·WWashington University School of Medicine·N/A·NCT06869850·1,600 enrolled

Evaluate the Efficacy and Safety of Amino Acid (15) Peritoneal Dialysis Solution in Peritoneal Dialysis Patients with Malnutrition.

Recruiting·CChengdu Qingshan Likang Pharmaceutical Co., Ltd·Phase 4·NCT06597201·400 enrolled

Double Duty Interventions and Its Impact on DBM Among Children Under Five Years Ethiopia: A Cluster Randomized Controlled Trial

Active, not recruiting·Debre Berhan University·Preclinical·NCT05791305·456 enrolled

Choline to Improve Malnutrition and Enhance Cognition

Active, not recruiting·WWashington University School of Medicine·Preclinical·NCT06154174·1,500 enrolled

An Individually Randomized, Partially Blinded, Controlled Trial of Choline-containing Ready-to-use Supplementary Food (C-RUSF) for Children With Moderate Acute Malnutrition to Reduce Deterioration to Severe Acute Malnutrition Compared to Standard RUSF.

Active, not recruiting·WWashington University School of Medicine·Preclinical·NCT06214897·1,515 enrolled

Pilot Study to Assess the Benefits and Sustainability of Regular Growth Monitoring (RGM) of Young Children in Villages in Guinea-Bissau

Active, not recruiting·TTrustees of Dartmouth College·Preclinical·NCT07584395·400 enrolled

Impact of School Meal Program on Nutritional Status and Academic Performance Among Primary School Children: An Interventional Study

Not yet recruiting·University of Veterinary and Animal Sciences, Lahore - Pakistan·Preclinical·NCT07800208·496 enrolled

Nutritional Status, Nutrition-Related Conditions, and Development of a Clinical Pathway for Nutritional Support in Hospitalized Patients Aged 65 Years and Older With Mental Disorders

Not yet recruiting·University Psychiatric Clinic Ljubljana·N/A·NCT07710456·450 enrolled

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Data sources: ClinicalTrials.gov (NIH) · OpenFDA (FDA) · ChEMBL (EMBL-EBI) · Open Targets (EBI/Sanger) · MedlinePlus (NIH) · PubMed (NIH) · SEC EDGAR (SEC)