VivoSeq
Other

Malnutrition

39

Pipeline Programs↗

9

Active Trials↗

16

Companies Involved↗

Malnutrition is a moderately active landscape with 39 programs across 16 companies. The most active players are Par Pharmaceutical, Inc., Salix, Asklepion Pharmaceuticals, LLC. 8 therapies are approved with 11 more in late-stage development.

Intelligence

Pipeline Metrics

Competitive Density

57/100

Pipeline Velocity

19/100

Mech. Concentration

17/100

Completion Rate

67/100

Attrition Rate

21/100

Competition

Competitive Landscape

Bubble size = clinical trials

Approved
Phase 3
Phase 2
Phase 1
Preclinical

Key Players

Top Companies Companies ranked by the number of pipeline programs they run for this disease.

P

Par Pharmaceutical, Inc.

1 program

Phase 1S

Salix

1 program

Phase 2A

Asklepion Pharmaceuticals, LLC

1 program

Phase 3Pfizer logo

Pfizer

3 programs

Phase 3C

Chengdu Qingshan Likang Pharmaceutical Co., Ltd

2 programs

ApprovedP

Pfizer's Upjohn has merged with Mylan to form Viatris Inc.

1 program

Approved

Pipeline

Programs by Phase

Preclinical13

Dexamethasone

Aspen Global Incorporated

Zinc

American Regent, Inc.

Nandrolone Decanoate

McNeil Consumer & Specialty Pharmaceuticals, a Division of McNeil-PPC, Inc.

Sulfadoxine Pyrimethamine

Pfizer

Albendazole.

GSK

Phase 12

PF-07258669

Pfizer

Oxandrolone

Par Pharmaceutical, Inc.

Phase 25

Teduglutide

Takeda

Budesonide

Salix

Hydroxyurea

Theravia

Megestrol Acetate

Bristol-Myers Squibb

N-Acetyl Glucosamine (ginnac)

Queen Mary University of London

Phase 311

Ceftriaxone

Conrado Roberto Hoffmann Filho

Glutamine

Sanofi

Metronidazole

DePuy Orthopaedics

Gentamicin

Schering-Plough

L-Citrulline

Asklepion Pharmaceuticals, LLC

Approved8

Testosterone Undecanoate

Grupo Espanol de Tumores Neuroendocrinos

Azithromycin

Pfizer's Upjohn has merged with Mylan to form Viatris Inc.

Mesalamine

Takeda

Thalidomide

Bristol-Myers Squibb

Amoxicillin

Global Antibiotics Research and Development Partnership

Analysis

Modality Breakdown

93%

Small molecule

43 of 46 classified programs — the dominant modality here.

7%ALL OTHERSVaccine24%Peptide12%

Small molecule leads; the ring shows all 46 classified programs, each share of the total. Modality classified for 100% of 49 pipeline programs.

Analysis

Trial Status

43

clinical trials

Completed18 · 42%
Unknown status7 · 16%
Recruiting7 · 16%
Withdrawn5 · 12%
Terminated4 · 9%
Not yet recruiting2 · 5%

Clinical Trials

Trial Activity

43 trials

Modified Dosage for Severe Acute Malnutrition
Recruiting·AAction Against Hunger USA·N/A·NCT06061484·2,400 enrolled
Pancrelipase With Nutritional Supplement in Patients at Risk of Malnutrition (EFFORT-ENZO)
Recruiting·—·N/A·NCT06826105·20 enrolled
Azithromycin as Adjunctive Treatment for Uncomplicated Severe Acute Malnutrition
Recruiting·UUniversity of California, San Francisco·Phase 4·NCT06010719·3,000 enrolled
Milk Fat Globule Membrane-Enhanced RUTF for Children With Severe Acute Malnutrition
Recruiting·WWashington University School of Medicine·N/A·NCT06869850·1,600 enrolled
Evaluate the Efficacy and Safety of Amino Acid (15) Peritoneal Dialysis Solution in Peritoneal Dialysis Patients with Malnutrition.
Recruiting·CChengdu Qingshan Likang Pharmaceutical Co., Ltd·Phase 4·NCT06597201·400 enrolled
Choline to Improve Malnutrition and Enhance Cognition
Recruiting·WWashington University School of Medicine·N/A·NCT06154174·1,500 enrolled
Implementation of Nutritional Treatment to Older Patients Discharged With the Liaison Team
Recruiting·HHerlev and Gentofte Hospital·Preclinical·NCT06706661·2,000 enrolled
Opportunistic Pneumococcal Immunisation Trial in MALnutrition
Not yet recruiting·—·Phase 4·NCT06817421·214 enrolled
Oral Citrulline Supplementation in COPD Patients With Malnutrition
Not yet recruiting·UUniversity Hospital, Grenoble·Phase 3·NCT06212765·60 enrolled
Malnutrition in Gastroenterology Patients
Completed·—·Phase 4·NCT00168935
Effectiveness of Oral Antibiotics in the Treatment of Severe Acute Malnutrition
Completed·WWashington University School of Medicine·N/A·NCT01000298·2,700 enrolled
Impact of the Use of Nandrolone on the Treatment of Malnutrition Induced by Cancer
Completed·—·N/A·NCT03263520·60 enrolled
High Protein Formula on Enteral Feeding in Clinical Improvement and Malnutrition at Intensive Care Unit Patients
Completed·HHasanuddin University·N/A·NCT04150978·60 enrolled
Nutritional, and WASH Related Education Intervention to Address Malnutrition of Early Adolescents in Pakistan
Completed·—·N/A·NCT06009198·635 enrolled
Therapeutic Approaches to Malnutrition Enteropathy
Completed·QQueen Mary University of London·Phase 2·NCT03716115·125 enrolled
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Data sources: ClinicalTrials.gov (NIH) · OpenFDA (FDA) · ChEMBL (EMBL-EBI) · Open Targets (EBI/Sanger) · MedlinePlus (NIH) · PubMed (NIH) · SEC EDGAR (SEC)