VivoSeq
Other

Mastectomy

64

Pipeline Programs↗

15

Active Trials↗

21

Companies Involved↗

Mastectomy is a moderately active landscape with 64 programs across 21 companies. The most active players are Roche, Hikma Pharmaceuticals LLC, Amring. 20 therapies are approved with 7 more in late-stage development.

Intelligence

Pipeline Metrics

Competitive Density

64/100

Pipeline Velocity

27/100

Mech. Concentration

12/100

Completion Rate

86/100

Attrition Rate

10/100

Competition

Competitive Landscape

Bubble size = clinical trials

Approved
Phase 3
Phase 2
Phase 1
Preclinical

Key Players

Top Companies Companies ranked by the number of pipeline programs they run for this disease.

Roche logo

Roche

1 program

Phase 2H

Hikma Pharmaceuticals LLC

1 program

Phase 2A

Amring

1 program

Phase 2R

Repros Therapeutics Inc.

1 program

Phase 2Eli Lilly logo

Eli Lilly

1 program

Phase 3F

Fresenius Kabi Oncology Ltd.

3 programs

Phase 3

Pipeline

Programs by Phase

Preclinical26

Dexmedetomidine

McNeil Consumer & Specialty Pharmaceuticals, a Division of McNeil-PPC, Inc.

Bupivacaine

Innocoll

Duloxetine

Alnylam Pharmaceuticals

Liposomal Bupivacaine

TLC Biopharmaceuticals, Inc.

Tizanidine

Legacy Health System

Phase 16

Cefazolin

Baxter Healthcare Corporation

Gentamicin

Schering-Plough

Mirtazapine

Organon and Co

Ifnα-2a

Sun Yat-Sen Memorial Hospital of Sun Yat-Sen University

Capule Gabapentin

Combined Military Hospital, Pakistan

Phase 25

Morphine

Hikma Pharmaceuticals LLC

Tranexamic Acid

Amring

Brivoligide

Adynxx, Inc.

Telapristone Acetate

Repros Therapeutics Inc.

Standard Bupivacaine

The University of Hong Kong

Phase 37

Ropivacaine

Fresenius Kabi Oncology Ltd.

Cephalexin

Eli Lilly

Lyrica

Pfizer's Upjohn has merged with Mylan to form Viatris Inc.

Bupivicaine

Thomas Jefferson University

Ketorolac IV

Islamabad Medical and Dental College

Approved20

EXPAREL

Pacira Pharmaceuticals, Inc

Fentanyl

Cephalon

Ketamine

Aultman Health Foundation

Dexamethasone

Aspen Global Incorporated

Lidocaine

MEDRx USA, Inc.

Analysis

Modality Breakdown

99%

Small molecule

100 of 101 classified programs — the dominant modality here.

1%ALL OTHERSPeptide1<1%

Small molecule leads; the ring shows all 101 classified programs, each share of the total. Modality classified for 100% of 104 pipeline programs.

Analysis

Trial Status

110

clinical trials

Completed66 · 60%
Unknown status18 · 16%
Recruiting7 · 6%
Withdrawn6 · 5%
Not yet recruiting6 · 5%
Terminated5 · 5%
Other2 · 2%

Clinical Trials

Trial Activity

110 trials

Post-mastectomy Recovery: Comparing Preoperative PECS-II Blocks With Intraoperative Pectoral Blocks
Recruiting·UUniversity of Cincinnati·Phase 4·NCT06574022·100 enrolled
Adding Magnesium Sulfate to Local Anesthetic in Combined Pectoral Nerve and Stellate Ganglion Block for Postoperative Pain Control After Modified Radical Mastectomy
Recruiting·—·N/A·NCT06815887·70 enrolled
The Effect of Dexmedetomidine and Esketamine Combined Infusion Quality of Sleep Undergoing Modified Radical Mastectomy
Recruiting·—·N/A·NCT06414941·105 enrolled
Adding Amantadine or Duloxetine to Pregabalin on Occurrence of Post Mastectomy Pain Syndrome
Recruiting·—·N/A·NCT07421427·150 enrolled
Investigating the Use of Intravenous Tranexamic Acid in Gender Affirming Mastectomy
Recruiting·UUniversity of California, San Francisco·Phase 2·NCT05794321·150 enrolled
Bupivacaine vs Placebo for Unilateral Mastectomy Surgical Site Post-operative Pain Control
Recruiting·MMemorial Sloan Kettering Cancer Center·Phase 3·NCT03351348·165 enrolled
A Comparative Analysis of REVOLVE, LipoGrafter, and Viality in Autologous Fat Grafting During Breast Surgery
Recruiting·WWeill Medical College of Cornell University·Preclinical·NCT04891510·135 enrolled
Intraoperative Pectoral Block vs IV Analgesia for Pain After Modified Radical Mastectomy
Active, not recruiting·IIslamabad Medical and Dental College·Phase 3·NCT07257874·60 enrolled
Quality of Recovery From Mastectomy With and Without PECS Blocks
Active, not recruiting·EEndeavor Health·N/A·NCT05795413·800 enrolled
Suzetrigine for Non-Mastectomy Breast Surgery
Not yet recruiting·UUniversity of California, San Diego·Phase 4·NCT07463430·120 enrolled
Preoperative Erector Spinae Plane Block Versus Paravertebral Plane Block in Decreasing Post Mastectomy Pain Syndrome
Not yet recruiting·National Cancer Institute, Egypt·N/A·NCT06036979·51 enrolled
Adding Magnesium Sulphate to Combined Pectointercostal Plane and Erector Spinae Plane Blocks for Acute and Chronic Post-Mastectomy Pain
Not yet recruiting·SSouth Egypt Cancer Institute·N/A·NCT07438366·60 enrolled
Selected Exercise Program on Upper Cross Syndrome Post-unilateral Mastectomy
Not yet recruiting·—·N/A·NCT07447024·60 enrolled
Biological and Clinical Underpinnings of Postoperative Pain - Mastectomy (BAC-UPP 1 Study)
Not yet recruiting·UUniversity of Alabama at Birmingham·N/A·NCT07271589·86 enrolled
Super-voltage Pulsed Radiofrequency of Stellate Ganglion Versus Super-voltage Pulsed Radiofrequency of T2 T3 Sympathetic Ganglia in Managing Postmastectomy Pain Syndrome.
Not yet recruiting·National Cancer Institute, Egypt·Preclinical·NCT07675096·75 enrolled
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Data sources: ClinicalTrials.gov (NIH) · OpenFDA (FDA) · ChEMBL (EMBL-EBI) · Open Targets (EBI/Sanger) · MedlinePlus (NIH) · PubMed (NIH) · SEC EDGAR (SEC)