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Other/Otitis Media

Otitis Media

10

Pipeline Programs↗

9

Active Trials↗

19

Companies Involved↗

Otitis media is an early-stage landscape with 10 programs across 19 companies. 1 program is in Phase 3.

Intelligence

Pipeline Metrics

Competitive Density

41/100

Pipeline Velocity

27/100

Mech. Concentration

50/100

Completion Rate

82/100

Attrition Rate

15/100

Pipeline

Programs by Phase

Preclinical9

Sulfamethoxazole-Trimethoprim

National Institute of Allergy and Infectious Diseases (NIAID)

Cefotaxime

Sterimax

Acetylcysteine

Arbor Pharmaceuticals, Inc.

Xylometazoline

Novartis

Amoxicillin for

GSK

Phase 1

No programs

Phase 2

No programs

Phase 31

Triamcinolone Acetonide

Bausch Health Americas, Inc.

Approved

No programs

Analysis

Trial Status

74

clinical trials

Completed50 · 68%

Terminated9 · 12%

Recruiting4 · 5%

Unknown status4 · 5%

Not yet recruiting3 · 4%

Active, not recruiting2 · 3%

Other2 · 3%

Clinical Trials

Trial Activity

74 trials

A Prospective Clinical Study of the Clikx Tympanostomy Tube Delivery System for Patients Requiring the Placement of Tympanostomy Tubes

Recruiting·CClinQure, Inc.·Preclinical·NCT07625657·80 enrolled

Parent-led Assessment and Recognition of AOM Using Digital Ear Imaging

Recruiting·TTurku University Hospital·Preclinical·NCT07640568·40 enrolled

Post-Market Clinical Follow-Up Study of the Solo+ Tympanostomy Tube Device

Recruiting·AAventaMed DAC·N/A·NCT07029997·160 enrolled

A Short Wave Infrared Otoscope for Objective Middle Ear Effusion Diagnosis

Recruiting·SStanford University·Preclinical·NCT06944795·100 enrolled

The Effects of Chronic Otitis Surgery on Virtual Subjective Vertical

Active, not recruiting·PPamukkale University·N/A·NCT04396145·30 enrolled

Utility of Advanced Ultrasound Otoscope In The Diagnosis of Acute Otitis Media

Active, not recruiting·BBaylor College of Medicine·N/A·NCT06429709·300 enrolled

EarFlo: A Non-Invasive Treatment for Otitis Media With Effusion & Eustachian Tube Dysfunction in Adults

Not yet recruiting·—·Preclinical·NCT07777302·100 enrolled

Comparative Effectiveness of Available Treatments for Sinus and Ear Infections in Children (Acute Otitis Media)

Not yet recruiting·—·Approved·NCT07730814·1,100 enrolled

Intranasal Corticosteroid Spray for Preventing Otitis Media With Effusion After Radiotherapy in Nasopharyngeal Carcinoma

Not yet recruiting·UUnion Hospital, Tongji Medical College, Huazhong University of Science and Technology·Phase 3·NCT07189572·168 enrolled

Impact of Mastoid and Middle Ear Volume on Pediatric Tympanoplasty

Completed·AAl-Azhar University·N/A·NCT07806461·40 enrolled

The Hearing for Learning Initiative - a Service-enhancement Model of Ear Health Facilitators to Address the Crisis in Ear and Hearing Health of Aboriginal Children in the Northern Territory: a Stepped-wedge Cluster Randomised Trial

Completed·MMenzies School of Health Research·Preclinical·NCT03916029·18 enrolled

Safety and Efficacy of EXE844 Otic Suspension in Otitis Media at Time of Tympanostomy Tube Insertion (OMTT) - Study 2

Completed·AAlcon Research·Phase 3·NCT02436304·404 enrolled

Open-Label Study of OTO-201 in Pediatric Subjects With a History of Otitis Media Requiring Tympanostomy Tubes

Completed·OOtonomy, Inc.·Phase 3·NCT02600559·501 enrolled

Effectiveness of Sulfamethoxazole-trimethoprim in the Treatment of Chronic Otitis Media

Completed·UUMC Utrecht·N/A·NCT00189098·101 enrolled

Homeopathic Ear Drops for Otitis Media Study

Completed·UUniversity of Washington·N/A·NCT01003210·210 enrolled

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Data sources: ClinicalTrials.gov (NIH) · OpenFDA (FDA) · ChEMBL (EMBL-EBI) · Open Targets (EBI/Sanger) · MedlinePlus (NIH) · PubMed (NIH) · SEC EDGAR (SEC)