Kenalog
(Triamcinolone Acetonide)ApprovedSmall molecule
Triamcinolone acetonide is a steroid medication used to reduce inflammation and suppress the immune system to treat conditions like allergies, asthma, skin rashes, joint inflammation, and autoimmune diseases.[2] Kenalog is currently approved and in use across 93 indications[4].[1]
Kenalog is one of 1150 small molecule programs targeting Myofascial Pain Syndrome. It is currently in Approved.
93
Indications
172
Total Trials
26
Active Trials
1,149
Competitors
17
FDA Applications
NDA/BLA/ANDA regulatory filings
8
Patents
Pipeline
Status by Indication[4][1]
Indication
Showing 10 of 90 indications
Competition
Competitive Landscape
2828 competitors in Breast Cancer
#DrugCompanyPhaseTrials
1Kenalog
BBausch Health Americas, Inc.
Approved
Nolvadex
SSan Diego Pacific Oncology & Hematology Associates
Preclinical
Blenoxane
Bristol-Myers SquibbPreclinical
Lupron
EEastern Cooperative Oncology Group
Preclinical
Spravato
WWim Janssens
Preclinical
Cortef
PPfizer's Upjohn has merged with Mylan to form Viatris Inc.
Preclinical
Chirocaine
PPurdue Pharma LP
Preclinical
Nubain
AAultman Health Foundation
Preclinical
Aquasol E
NNational Eye Institute (NEI)
Preclinical
Vfend
PPrism Pharmaceuticals
Preclinical
Ranked by pipeline maturity and clinical activity. Current drug highlighted in teal.
Timeline
Expected Milestones
Clinical
Trials by Indication[1]
Diabetic Macular Edema14 trials
Show 11 more trials
Suprachoroidal Triamcinolone Versus Posterior Subtenon Triamcinolone Alone or Formulated in the Management of Diabetic Macular Edema.
Completed·—·N/A·NCT05464953·75 enrolled
Osteoarthritis11 trials
Cell Therapy With Cellistem-OA for Symptomatic Knee Osteoarthritis
Unknown status·FFundación Oftalmológica de Santander Clínica Carlos Ardila Lulle·Phase 1/2·NCT04863183·30 enrolled
Intra-articular Tenoxicam Versus Triamcinolone Acetonide in Knee Osteoarthritis Management
Completed·—·N/A·NCT07194135·100 enrolled
Show 8 more trials
The Efficacy of Intra-articular Triamcinolone Acetonide 5mg vs. 10 mg vs. 40 mg in Patients With Knee Osteoarthritis
Recruiting·—·Phase 4·NCT05806021·327 enrolled
Alopecia Areata10 trials
Phototoxic Doses of Ultraviolet A for Treatment of Alopecia Areata
Completed·—·N/A·NCT01559584·40 enrolled
Methotrexate Versus Triamcinilone Acetonide in Treatment of Recalcitrant Alopecia Areata
Unknown status·—·N/A·NCT06088147·34 enrolled
Show 7 more trials
Cryotherapy Versus Steroids In Alopecia Areata:Trichoscopic Evaluation
Unknown status·—·Phase 4·NCT03473600·40 enrolled
Intralesional Vitamin D in Alopecia Areata
Unknown status·—·Phase 1/2·NCT04660786·40 enrolled
Topical 5% Minoxidil and Potent Topical Corticosteroid Versus Intralesional Corticosteroid in the Treatment of Alopecia Areata
Completed·—·Phase 4·NCT03535233·40 enrolled
Oral Lichen Planus10 trials
Topical Erythropoietin Hydrogel in Management of Oral Lichen Planus
Unknown status·—·Phase 3·NCT06135259·18 enrolled
Evaluation of Green Tea as Antioxidant Agent in Management of Oral Lichen Planus
Completed·—·Phase 3·NCT02329600·40 enrolled
Efficacy of Coconut Gel Compared to Corticosteroid Gel in the Management of Oral Lichen Planus
Not yet recruiting·—·Phase 4·NCT07100145·30 enrolled
Show 7 more trials
Efficacy of Intralesional Injection of Platelet Rich Plasma in the Treatment of Patients With Erosive Oral Lichen Planus
Completed·—·Phase 2·NCT03293368·20 enrolled
Thyme Honey for Management of Oral Lichen Planus
Enrolling by invitation·—·Phase 1/2·NCT06810752·30 enrolled
Glucosamine as a Novel Adjunctive Therapy in Oral Lichen Planus
Completed·—·Phase 4·NCT02858297·30 enrolled
Keloid9 trials
Show 6 more trials
80 more indications
Carpal Tunnel Syndrome6 trials
Show 3 more trials
Does it Matter the Volume of Injectate on the Outcome of Ultrasound-guided Perineural Injection for Carpal Tunnel Syndrome
Not yet recruiting·—·Phase 4·NCT07283874·35 enrolled
Steroid5 trials
MCI4 trials
Cataract4 trials
Corticosteroid Injection Combined With Cataract Surgery in Diabetic Eyes.
Completed·—·Phase 2/3·NCT05413330·73 enrolled
Show 1 more trial
Treatment4 trials
Adhesive Capsulitis4 trials
Macular Edema3 trials
Steroid Injection3 trials
Retinal Vein Occlusion3 trials
Hyaluronic Acid2 trials
Cystoid Macular Edema2 trials
Asthma2 trials
Age-Related Macular Degeneration2 trials
Arthritis2 trials
Atopic Dermatitis2 trials
Bursitis2 trials
Proliferative Diabetic Retinopathy2 trials
Frozen Shoulder1 trial
Oral ulcer1 trial
Diode Laser Versus Topical Corticosteroids in Management of Oral Ulcers in Behcet's Disease
Unknown status·—·N/A·NCT03771768·38 enrolled
Desmoid Tumor1 trial
Optical Coherence Tomography1 trial
Thyroid Eye Disease1 trial
AMD1 trial
Adjunctive Photodynamic Therapy + Aflibercept vs. Afilbercept Alone for PDA in NV AMD
Withdrawn·—·N/A·NCT02457026
Epidural Analgesia1 trial
Thoracic Epidural Analgesia in Flail Chest
Unknown status·—·Phase 2/3·NCT03413059·40 enrolled
Biomarkers1 trial
Bevacizumab1 trial
Melanoma1 trial
TTT Versus TTT and Triamcinolone to Decrease Exudation in Choroidal Melanoma After Proton Beam Therapy
Unknown status·—·Phase 4·NCT02379000·50 enrolled
Retinal Diseases1 trial
Results of Suprachoroidal Steroids Injections in Two Chorioretinal Diseases
Unknown status·—·Phase 2/3·NCT05337332·50 enrolled
Greater Trochanteric Pain Syndrome1 trial
Efficacy of Platelet Rich Plasma vs. Corticosteroid Injections for Treating Greater Trochanteric Pain Syndrome
Unknown status·—·Phase 1·NCT02031367·50 enrolled
Radius Fracture1 trial
Polypoidal choroidal vasculopathy1 trial
Intravitreal Ranibizumab and TA Combination Therapy vs. Ranibizumab Monotherapy in Polypoidal Choroidal Vasculopathy
Unknown status·—·Phase 4·NCT02806752·120 enrolled
Contact Dermatitis1 trial
Post Operative Sore Throat1 trial
Lichen Planus1 trial
Corticosteroids1 trial
Lymphoma1 trial
Tendinopathy1 trial
Uveitis1 trial
Diabetic Retinopathy1 trial
Botulinum Toxin1 trial
Otitis media1 trial
ART1 trial
Prevention1 trial
Quality of Life1 trial
Interaction1 trial
Irritation1 trial
Nasal Obstruction1 trial
Cicatricial Alopecia1 trial
Methotrexate1 trial
Thyroid Associated Orbitopathy Treatment by Methotrexate Against Triamcinolone Periocular Injections
Completed·—·Phase 2·NCT05429450·18 enrolled
Colchicine1 trial
Suprascapular Nerve Block1 trial
Rhinitis1 trial
Pemphigus Vulgaris1 trial
Comparison Between Injections of Steroids and Autologous Platelet Rich Plasma in the Oral Erosions of Pemphigus Vulgaris
Completed·—·Phase 3·NCT02828163·11 enrolled
Breast Cancer1 trial
Glioblastoma1 trial
Refractory1 trial
Shoulder Impingement Syndrome1 trial
Contracture1 trial
Fluorouracil1 trial
Clinical Trial1 trial
Oral Submucous Fibrosis1 trial
Alternating Triamcinolone and Platelet-Rich Plasma Therapy for Oral Submucous Fibrosis
Not yet recruiting·—·N/A·NCT07277998·40 enrolled
Necrosis1 trial
Prurigo1 trial
Otitis Media With Effusion1 trial
Intranasal Corticosteroid Spray for Preventing Otitis Media With Effusion After Radiotherapy in Nasopharyngeal Carcinoma
Not yet recruiting·UUnion Hospital, Tongji Medical College, Huazhong University of Science and Technology·Phase 3·NCT07189572·168 enrolled
Burn1 trial
Unspecified2 trials
PST/Laser v. Laser Alone for CSME
Unknown status·—·Phase 2·NCT00229918·60 enrolled
Regulatory
FDA Approval Timeline[5]
Jan 1, 1982
TRIAMCINOLONE ACETONIDE
NDA NDA011601
Jan 1, 1982
KENALOG
NDA NDA012104
Jan 1, 1982
KENALOG IN ORABASE
NDA NDA012097
Jan 1, 1982
KENALOG-10
NDA NDA012041
Jan 1, 1982
KENALOG
NDA NDA011602
Jan 1, 1982
TRIAMCINOLONE ACETONIDE
NDA NDA011600
Jan 1, 1982
KENALOG-40
NDA NDA014901
Apr 23, 1982
AZMACORT
NDA NDA018117
Oct 16, 1987
TRIAMCINOLONE ACETONIDE
NDA NDA019503
Jul 11, 1991
NASACORT
NDA NDA019798
Feb 4, 2000
ALLERNAZE
NDA NDA020120
Apr 7, 2004
NASACORT HFA
NDA NDA020784
Nov 29, 2007
TRIESENCE
NDA NDA022048
Jun 16, 2008
TRIVARIS
NDA NDA022220
Oct 11, 2013
NASACORT ALLERGY 24 HOUR
NDA NDA020468
Oct 6, 2017
ZILRETTA
NDA NDA208845
Oct 22, 2021
XIPERE
NDA NDA211950
Sources
References
- [1]
- [2]MedlinePlus Drug Information — Kenalog drug information. U.S. National Library of Medicine, National Institutes of Health.
- [3]
- [4]Open Targets Platform — Drug–disease associations for Triamcinolone Acetonide. EMBL-EBI & Wellcome Sanger Institute.
- [5]
- [6]
- [7]
Details
Drug Info
Quick Facts
- Mechanism of Action
- Glucocorticoid Receptor Agonist[3]
- Modality
- Small molecule[3]
- Highest Phase
- Approved[1]
- Company
- BBausch Health Americas, Inc.