VivoSeq
Ophthalmology

Proliferative Diabetic Retinopathy

35

Pipeline Programs

3

Active Trials

10

Companies Involved

Proliferative Diabetic Retinopathy is a moderately active landscape with 35 programs across 10 companies. The most active players are Regeneron, EyePoint Pharmaceuticals, Inc., Par Pharmaceutical, Inc.. 7 therapies are approved with 10 more in late-stage development.

Pipeline Metrics

Competitive Density

54/100

Pipeline Velocity

6/100

Mech. Concentration

14/100

Completion Rate

87/100

Attrition Rate

9/100

Competitive Landscape

Bubble size = clinical trials

Approved
Phase 3
Phase 2
Phase 1
Preclinical

Programs by Phase

Modality Breakdown

62%

Small molecule

23 of 37 classified programs — the dominant modality here.

38%ALL OTHERSMonoclonal antibody822%Protein / enzyme514%Peptide13%

Small molecule leads; the ring shows all 37 classified programs, each share of the total. Modality classified for 100% of 37 pipeline programs.

Trial Status

53

clinical trials

Completed34 · 64%
Unknown status11 · 21%
Terminated3 · 6%
Withdrawn2 · 4%
Enrolling by invitation1 · 2%
Recruiting1 · 2%
Other1 · 2%

Trial Activity

53 trials

High Dose Eylea for Proliferative Diabetic Retinopathy Outcomes
Active, not recruiting··Phase 4·NCT07118670·40 enrolled
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Data sources: ClinicalTrials.gov (NIH) · OpenFDA (FDA) · ChEMBL (EMBL-EBI) · Open Targets (EBI/Sanger) · MedlinePlus (NIH) · PubMed (NIH) · SEC EDGAR (SEC)