VivoSeq
Infectious Disease

Urinary Tract Infection

129

Pipeline Programs↗

20

Active Trials↗

46

Companies Involved↗

Urinary Tract Infection is a highly competitive landscape with 129 programs across 46 companies. The most active players are Roche, Adaptive Phage Therapeutics, Inc., Menarini. 42 therapies are approved with 40 more in late-stage development.

Intelligence

Pipeline Metrics

Competitive Density

74/100

Pipeline Velocity

19/100

Mech. Concentration

28/100

Completion Rate

81/100

Attrition Rate

13/100

Competition

Competitive Landscape

Bubble size = clinical trials

Approved
Phase 3
Phase 2
Phase 1
Preclinical

Key Players

Top Companies Companies ranked by the number of pipeline programs they run for this disease.

Roche logo

Roche

1 program

Phase 1A

Adaptive Phage Therapeutics, Inc.

2 programs

Phase 2Menarini logo

Menarini

1 program

Phase 2E

Entasis Therapeutics

1 program

Phase 2P

Pinnacle Pharmaceuticals, Inc.

1 program

Phase 2Qilu Pharmaceutical Co., Ltd. logo

Qilu Pharmaceutical Co., Ltd.

1 program

Phase 2

Pipeline

Programs by Phase

Preclinical14

Amikacin

Insmed Incorporated

Imipenem

Pfizer

Empagliflozin

Boehringer Ingelheim

Antibiotic

Pfizer

Dipeptidyl Peptidase-4 Inhibitors

Boehringer Ingelheim

Phase 14

RO7079901

Roche

Frio Oral Rinse

Biomedical Development Corporation

GSK3882347

GSK

Ceftriaxon

International Maternal Pediatric Adolescent AIDS Clinical Trials Group

Phase 229

Cholecalciferol

Hyundai Pharmaceutical Co., LTD.

Ceftazidime

Philadelphia Eye Associates

Cephalexin

Eli Lilly

Phage Therapy

Adaptive Phage Therapeutics, Inc.

Bacteriophage Therapy

Adaptive Phage Therapeutics, Inc.

Phase 340

Meropenem

B. Braun Medical Inc.

Ceftriaxone

Conrado Roberto Hoffmann Filho

Methylprednisolone

Pfizer

Dexamethasone

Aspen Global Incorporated

Amoxicillin/clavulanate

Bayer

Approved42

Fluconazole

Pfizer's Upjohn has merged with Mylan to form Viatris Inc.

Levofloxacin

Wim Janssens

Estradiol

Novo Nordisk

Midazolam

Conrado Roberto Hoffmann Filho

Gentamicin

Schering-Plough

Analysis

Trial Status

164

clinical trials

Completed98 · 60%
Unknown status22 · 13%
Terminated16 · 10%
Recruiting13 · 8%
Withdrawn6 · 4%
Active, not recruiting5 · 3%
Other4 · 2%

Clinical Trials

Trial Activity

164 trials

A Study to Assess How Vaborem® is Taking up in the Body and Tolerated in Paediatric Patients With Gram Negative Infections, Including But Not Restricted to Complicated Urinary Tract Infections
Recruiting·Menarini logoMenarini·Phase 2·NCT06828848·44 enrolled
Vitamin C Effectiveness in Preventing Urinary Tract Infections After Gynecological Surgeries
Recruiting·—·Phase 2·NCT05913180·180 enrolled
Is Methenamine Prophylaxis for Urinary Tract Infection After Midurethral Sling as Effective as Antibiotic Prophylaxis?
Recruiting·—·N/A·NCT06810687·190 enrolled
Oral Antibiotics Alone in Children Aged 4 Weeks to 2 Months With a Urinary Tract Infection
Recruiting·—·N/A·NCT05819229·125 enrolled
A Study to Evaluate the Safety, Tolerability, and Pharmacokinetics of Meropenem-Vaborbactam in Children With Complicated Urinary Tract Infection, Including Acute Pyelonephritis
Recruiting·MMelinta Therapeutics, Inc.·Phase 2·NCT06672978·66 enrolled
Assess the Efficacy of OM-89 vs Placebo in Reducing Antibiotic Consumption Associated With the Treatment of Urinary Tract Infections in Patients With Neurogenic Bladder
Recruiting·—·Phase 3·NCT06588010·110 enrolled
Gag Therapy for Recurrent Urinary Tract Infection Assessing Comparability to International Nitrofurantoin Gold Standard Study
Recruiting·RRadboud University Medical Center·Phase 4·NCT05652374·100 enrolled
A Trial of HRS-8427 in the Treatment of Adults With Complicated Urinary Tract Infection, Including Acute Pyelonephritis
Recruiting·JJiangsu HengRui Medicine Co., Ltd.·Phase 3·NCT06569056·578 enrolled
Potentiated Aminoglycosides in Postoperative Urinary Tract Infection Prophylaxis
Recruiting·—·Phase 1·NCT05761405·90 enrolled
Pivmecillinam as Oral Step-Down Treatment for Escherichia Coli Febrile Urinary Tract Infection Versus Standard of Care
Recruiting·UUppsala University·Phase 4·NCT07236944·560 enrolled
Fosfomycin Versus Standard of Care in Children With Antibiotic-resistant Urinary Tract Infections
Recruiting·UUniversity of Sydney·Phase 3·NCT05709028·300 enrolled
Antibiotics for Delirium in Older Adults With No Clear Urinary Tract Infection
Recruiting·MMount Sinai Hospital, Canada·N/A·NCT06004739·550 enrolled
Bacterial Interference for Preventing Recurrent Urinary Tract Infection - New Ways of Treatment
Recruiting·OOdense University Hospital·N/A·NCT04846803·80 enrolled
Individualized Homeopathy to Reduce the Use of Antibiotics in Women With Recurrent Uncomplicated Urinary Tract Infections
Active, not recruiting·TTechnical University of Munich·Phase 4·NCT05545514·220 enrolled
Preference of Women With Recurrent Urinary Tract Infection for Vaginal Estradiol Tablet vs Cream
Active, not recruiting·WWake Forest University Health Sciences·Phase 4·NCT05723601·21 enrolled
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Data sources: ClinicalTrials.gov (NIH) · OpenFDA (FDA) · ChEMBL (EMBL-EBI) · Open Targets (EBI/Sanger) · MedlinePlus (NIH) · PubMed (NIH) · SEC EDGAR (SEC)