Antibiotic

Phase 3Small molecule

Pfizer

Antibiotic is one of 355 small molecule programs targeting Abscess. It is currently in Phase 3.

Indications

Total Trials

Active Trials

354

Competitors

Pipeline

Status by Indication[3][1]

Indication

AbscessActive, not recruiting

Wound HealingActive, not recruiting

AppendicitisActive, not recruiting

Complicated AppendicitisActive, not recruiting

Neonatal SepsisActive, not recruiting

Chronic Obstructive Pulmonary DiseaseActive, not recruiting

MiscarriageActive, not recruiting

DiverticulitisActive, not recruiting

Prostate CancerActive, not recruiting

Acute Myeloid LeukemiaActive, not recruiting

AbscessPreclinical

Active, not recruiting

Wound HealingPreclinical

Active, not recruiting

AppendicitisPreclinical

Active, not recruiting

Complicated AppendicitisPreclinical

Active, not recruiting

Neonatal SepsisPreclinical

Active, not recruiting

Chronic Obstructive Pulmonary DiseasePreclinical

Active, not recruiting

MiscarriagePreclinical

Active, not recruiting

DiverticulitisPreclinical

Active, not recruiting

Prostate CancerPhase 3

Active, not recruiting

Acute Myeloid LeukemiaPreclinical

Active, not recruiting

Showing 10 of 20 indications

Competition

Competitive Landscape

314 competitors in Prostate Cancer

#DrugCompanyPhaseTrials

Zoladex

TTerSera Therapeutics LLC

Phase 3

35 2

Rubraca

Bristol-Myers Squibb

Phase 3

9 3

Truqap

AstraZeneca

Phase 3

2 4

Antibiotic

Pfizer

Phase 3

1 5

Piflufolastat F 18

Novartis

Phase 3

1 6

Rhpsma-7.3 (18f)

BBlue Earth Diagnostics

Phase 3

4 7

Trexall

Jazz Pharmaceuticals

Preclinical

—8

Jatenzo

GGrupo Espanol de Tumores Neuroendocrinos

Preclinical

2 9

Ranexa

MMenarini International Operations Luxembourg SA

Preclinical

1 10

Botox

VVitae Pharmaceuticals Inc., an Allergan affiliate

Preclinical

Ranked by pipeline maturity and clinical activity. Current drug highlighted in teal.

Timeline

Expected Milestones

Q1 2027

Phase 2Recruiting

Safety and Efficacy

NCT05695261

Q3 2027

Phase 3Active, not recruiting

Prostate Cancer

NCT01407263

Phase 1/2Not yet recruiting

Granuloma

NCT07454772

Q4 2027

N/ARecruiting

Clinical Trial

NCT07077122

Q2 2028

Phase 3Recruiting

Premature Rupture of Membranes

NCT07107477

N/AActive, not recruiting

Ciprofloxacin

NCT04678869

Clinical

Trials by Indication[1]

Antibiotic Prophylaxis8 trials

Timing of Antibiotic Prophylaxis for Cesarean Deliveries

Completed·UUniversity of Florida·N/A·NCT00805545·400 enrolled

Antibiotic Prophylaxis in Percutaneous Nephrostomy Placements and Replacements for Malignant Urinary Tract Obstruction

Completed·—··NCT06801405·320 enrolled

Topical Antibiotic Prophylaxis for Eyelids

Completed·UUniversity of California, San Francisco·Phase 4·NCT03199911·401 enrolled

Show 5 more trials

Antibiotic Prophylaxis in Rectal Cancer Surgery: Oral With Intravenous Versus Intravenous Antibiotics.

Unknown status·SState Scientific Centre of Coloproctology, Russian Federation·N/A·NCT03436719·280 enrolled

Antibiotic Prophylaxis to Prevent Post-procedure UTI After VCUG

Unknown status·HHamilton Health Sciences Corporation·Phase 4·NCT05438082·84 enrolled

Effects of Antibiotic Prophylaxis on Recurrent UTI in Children

Completed·LLondon Health Sciences Centre Research Institute OR Lawson Research Institute of St. Joseph's·Phase 4·NCT02357758·59 enrolled

Vascular Surgical Antibiotic Prophylaxis Study (VSAPS 2)

Unknown status·—·Phase 4·NCT01612052·200 enrolled

The Effect of Pre-operative Single Dose Antibiotic Prophylaxis on the Post-operative Implant Success

Unknown status·—·N/A·NCT04856319·50 enrolled

Antibiotics7 trials

Antibiotics in Free Flaps Reconstructions

Completed·TTechnical University of Munich·Phase 4·NCT02436083·350 enrolled

Antibiotics, Gastric Bypass, and the Microbiome

Completed·MMedical College of Wisconsin·Phase 1·NCT05367479·23 enrolled

Post-operative Antibiotics; Effects on Risk of Infection After Cochlear Implant Surgery

Unknown status·OOdense University Hospital··NCT06177444·920 enrolled

Show 4 more trials

Comparison The Postoperative Effects of Local and Systemic Antibiotics Applied With Platelets Rich Fibrin

Completed·CCeren Melahat Donmezer··NCT04989127·75 enrolled

Pharmacokinetics (PK) of Antistaphylococcal Antibiotics in Infants (NICHD-2012-02-Staph Trio)

Completed·PPhillip Brian Smith·Phase 1·NCT01728363·63 enrolled

The Effect of Oral Antibiotics on Synovial Fluid and Differential for the Diagnosis of Infection

Withdrawn·RRush University Medical Center·N/A·NCT03551847

"Enhancing Surgical Safety in Developing Nations: Investigating Antibiotics' Role in Hand Surgeries."

Unknown status·MMarcos Felipe Marcatto de Abreu·N/A·NCT05990842·51 enrolled

Antibiotic2 trials

Antibiotic "Dysbiosis" in Preterm Infants

Completed·UUniversity of Florida·Phase 2·NCT02784821·98 enrolled

Evaluation of the Impact of the Modification of Antibiotic Susceptibility Testing on Antibiotic Prescriptions

Unknown status·—··NCT05902299·199 enrolled

Diverticulitis2 trials

Antibiotic Therapy of Acute Uncomplicated Colonic Diverticulitis

Completed·UUppsala University·N/A·NCT01008488·600 enrolled

Effectiveness and Safety of Outpatient Treatment of Uncomplicated Acute Diverticulitis Without Antibiotics

Enrolling by invitation·MMonica Mengual Ballester·N/A·NCT06517264·282 enrolled

Gut Microbiome2 trials

Effects of IAP-EOGBSD on Maternal Vaginal Microbiome, Offspring's Gut Microbiome and Metabolites.

Unknown status·ZZhujiang Hospital··NCT05738473·492 enrolled

Effect of Probiotic on Gut Microbiome and Bacterial Translocation in Healthy Asian Volunteers

Unknown status·—·Phase 4·NCT05083572·32 enrolled

53 more indications

Pneumonia2 trials

New Antibiotic to Treat Patients With Community-acquired Pneumonia Due to a Specific Bacteria (S. Pneumoniae Pneumonia)

Completed· Pfizer logo

Pfizer·Phase 3·NCT00035269·230 enrolled

Alternative Treatment Strategies for Stenotrophomonas Maltophilia Pneumonia

Completed·MMethodist Health System··NCT06112938·110 enrolled

Third Molar Surgery2 trials

Investigation of Effectiveness of Local Antibiotic With Platelet Rich Fibrin on Third Molar Surgery Outcomes In Vivo

Completed·CCeren Melahat Donmezer··NCT05678296·60 enrolled

LED Therapy for Third Molar Surgery

Not yet recruiting·HHuashan Hospital·Phase 1·NCT06640439·50 enrolled

Infections2 trials

Periodical Presumptive Treatment for the Control of Gonococcal Infections Among Sex Workers

Completed·—·Phase 4·NCT01329588·636 enrolled

Use of Boric Acid in Combination With Probiotics for the Treatment of Vaginal Infections

Completed·LLaboratorios Ordesa·Phase 4·NCT02860845·48 enrolled

Randomized Controlled Trial2 trials

Randomized Controlled Trial of Different Antibiotic Duration Prior to Prostate Enucleation Surgery

Not yet recruiting·OOhio State University·Phase 3·NCT07209150·250 enrolled

Prophylactic Antibiotics for Manual Removal of Retained Placenta in Vaginal Birth: a Randomized Controlled Trial

Unknown status·HHadassah Medical Organization·N/A·NCT01945450·300 enrolled

Appendicitis1 trial

Antibiotics vs Surgery in Acute Appendicitis

Active, not recruiting·—·N/A·NCT07492329·400 enrolled

Chronic Obstructive Pulmonary Disease1 trial

Study to Evaluate the Clinical Value and Safety of Xiyanping Injection in the Treatment of Acute Exacerbation of Chronic Obstructive Pulmonary Disease(COPD) Based on Real-world Clinical Data

Not yet recruiting·JJiangxi Qingfeng Pharmaceutical Co. Ltd.··NCT06754865·1,140 enrolled

Child Health1 trial

Researchers At UC San Diego Are Learning About the Benefits of Human Milk and How It Influences Infant and Child Health

Recruiting·UUniversity of California, San Diego··NCT05553743·5,000 enrolled

Urinary Tract Infection1 trial

Asymptomatic Bacteriuria & Risk of Urinary Tract Infection in Renal Transplants

Unknown status·—··NCT01349738·200 enrolled

Acute Myeloid Leukemia1 trial

Efficacy of Antibiotic Short Course for Bloodstream Infections in Acute Myeloid Leukemia Patients With Febrile Neutropenia

Completed·PPoitiers University Hospital··NCT04910698·104 enrolled

Sepsis1 trial

Short-course Antimicrobial Therapy in Sepsis

Unknown status·OOspedale Santa Maria delle Croci·Phase 2·NCT02899143·320 enrolled

Pregnancy1 trial

Management of Sub-Clinical Bacteriuria in Pregnancy

Completed·TThe University of Texas Health Science Center, Houston·Phase 4·NCT03275623·60 enrolled

Pediatric Patients1 trial

Perioperative Antibiotic Choices for Surgical Prophylaxis in Penicillin-allergic Pediatric Patients

Completed·JJoseph D. Tobias··NCT02036840·513 enrolled

MPA1 trial

Comparison of Two Antimicrobial Therapy Duration for Spondylodiscitis

Completed·AAssistance Publique - Hôpitaux de Paris·Phase 4·NCT00764114·351 enrolled

Immunology1 trial

SHIFT: Studying HIV Immunology After Fecal Transplant

Withdrawn·MMassachusetts General Hospital·Phase 1/2·NCT03163784

TED1 trial

Italian Study Group on Complicated Diverticulosis

Completed·GGruppo Italiano per lo Studio della Diverticolite Complicata··NCT01276886

Complicated Appendicitis1 trial

Per Oral Versus Intravenous Postoperative Antibiotics After Surgery for Complicated Appendicitis.

Completed·ZZealand University Hospital·N/A·NCT04803422·3,193 enrolled

Ciprofloxacin1 trial

CiproPAL (Ciprofloxacin Prophylaxis in Acute Leukaemia)

Active, not recruiting·UUniversity College, London·N/A·NCT04678869·313 enrolled

Ventilator-Associated Pneumonia1 trial

Antibiotic Therapy Practices for Ventilator-Associated Pneumonia (PETUNIA)

Recruiting·FFrench Society for Intensive Care··NCT06243094·1,060 enrolled

Pyelonephritis1 trial

Treatment of Acute Pyelonephritis With Gram Negative Strains in Infants and Children Less Than 3 Years Old

Completed·AAssistance Publique - Hôpitaux de Paris·Phase 4·NCT00136656·700 enrolled

Trial1 trial

The Burn Glove Trial - Hand Burn Dressing Pilot

Withdrawn·SSouthern Illinois University·N/A·NCT02318056

Cystic Fibrosis1 trial

Evaluation of Ciprofloxacin for Inhalation to Cystic Fibrosis Patients With P. Aeruginosa

Withdrawn·AAradigm Corporation··NCT01090908

Mohs Micrographic Surgery1 trial

Nasal Iodine Swab Versus Oral Antibiotic to Prevent Surgical Site Infection After Undergoing Mohs Micrographic Surgery

Withdrawn·MMayo Clinic·N/A·NCT06207786

Unknown status·—··NCT06053528·2,000 enrolled

Safety and Efficacy1 trial

Evaluating the Safety and Efficacy of Oral Encapsulated Microbiota Transplantation Therapy in Peanut Allergic Patients

Recruiting·RRima Rachid·Phase 2·NCT05695261·37 enrolled

Bacterial Vaginosis1 trial

Multistrain Probiotics Against Bacterial Vaginosis

Terminated·IInstitut AllergoSan Pharma GmbH·Phase 1·NCT06888518·56 enrolled

Spine Surgery1 trial

The Effect of Prolonged Postoperative Antibiotics Administration on Rate of Infection in Patients Undergoing Posterior Spine Surgery Requiring a Hemovac Drain

Completed·TThe London Spine Centre·Phase 4·NCT01458223·645 enrolled

Breast Reconstruction1 trial

Antibiotics and Tissue Expanders in Breast Reconstruction

Withdrawn·EEmory University·Phase 4·NCT01899690

Granuloma1 trial

Antibiotics vs Corticosteroids in Treatment of Granulomatous Lobular Mastitis

Not yet recruiting·—·Phase 1/2·NCT07454772·72 enrolled

Multiple Myeloma1 trial

Bendamustine in Combination With Lenalidomide and Dexamethasone in Refractory or Relapsed Multiple Myeloma

Completed·RRobert Redner, MD·Phase 1·NCT01042704·29 enrolled

Wound Healing1 trial

A Study to Assess Wound Healing Efficacies of Different Clean, Treat, and Protect Wound Care Regimens Compared to Standard of Care and Untreated

Completed·JJohnson & Johnson Consumer Inc. (J&JCI)·N/A·NCT05045183·34 enrolled

Microbiota1 trial

Treatment of CDI and Recurrence With Fecal Microbiota Transplant Using Promicrobioma

Unknown status·HHospital Universitario Evangelico de Curitiba·Phase 3·NCT06107569·24 enrolled

Laparoscopic Cholecystectomy1 trial

The Role of Postoperative Antibiotics in Laparoscopic Cholecystectomy

Recruiting·MMinia University Hospital·Phase 4·NCT06607887·300 enrolled

Premature rupture of membranes1 trial

TAILORED Therapeutic Regime in Patients With Preterm Premature Rupture Of Membranes to Prolong Pregnancy, Improve Maternal and Neonatal Outcomes, and Reduce Antibiotic Burden

Recruiting·TThe Central and Eastern European Gynecologic Oncology Group·Phase 3·NCT07107477·138 enrolled

Cardiac Arrest1 trial

Ceftriaxone to PRevent pneumOnia and inflammatTion aftEr Cardiac arresT (PROTECT)

Terminated·—·Phase 2·NCT04999592·53 enrolled

Indocyanine Green (ICG)1 trial

Indocyanine Green (ICG) and SPY Imaging for Assessment of Burn Healing

Completed·TTexas Tech University Health Sciences Center·N/A·NCT02766244·3 enrolled

Intensive Care Unit1 trial

Selective Decontamination of the Digestive Tract in Intensive Care Unit Patients

Completed·TThe George Institute·Phase 3·NCT02389036·20,010 enrolled

Clinical Trial1 trial

Evaluation of the Systemic Burden of Non-surgical Periodontal Therapy: A Randomized Clinical Trial on Five Different Treatment Protocols

Recruiting·NNational and Kapodistrian University of Athens·N/A·NCT07077122·75 enrolled

Abscess1 trial

Oral Antibiotics for Anal Abscess

Unknown status·GGermans Trias i Pujol Hospital·N/A·NCT03643198·210 enrolled

Cervicitis1 trial

Cervicitis by Iontophoresis

Unknown status·OOctober 6 University·Phase 1·NCT05675293·40 enrolled

Sinusitis1 trial

Antibiotics Versus Therapeutic Ultrasound for Sinusitis

Completed·NNorwegian University of Science and Technology·Phase 3·NCT00934830·48 enrolled

Prophylaxis1 trial

PReclude Infection EVEnts With No Prophylaxis Transperineal Biopsy

Completed·WWeill Medical College of Cornell University·N/A·NCT04843566·687 enrolled

Anticoagulation1 trial

No Monitoring of Post-filter Ionized Calcium in Regional Citrate Anticoagulation

Completed·—·N/A·NCT04792424·50 enrolled

Neonatal sepsis1 trial

Treatment Outcome With Antibiotic Use and Its Resistance Pattern Among Patient With Neonatal Sepsis

Unknown status·—··NCT05742477·100 enrolled

Preoperative1 trial

Use of Preoperative and Postoperative Antimicrobial Treatment

Unknown status·SSunnybrook Health Sciences Centre·Phase 4·NCT04707092·304 enrolled

Tonsillectomy1 trial

Comparing Healthcare Utilization Between Adenotonsillectomy Patients With and Without Postoperative Antibiotic Use

Completed·UUniversity of Missouri-Columbia·N/A·NCT01561703·58 enrolled

Central Nervous System1 trial

Effect of Probiotics on Central Nervous System Functions in Humans

Completed·UUniversity Hospital Tuebingen·Phase 2/3·NCT02793193·54 enrolled

Antibiotic Therapy1 trial

Short Against Long Antibiotic Therapy for Infected Orthopedic Sites

Completed·—·Phase 3·NCT05499481·495 enrolled

Infection1 trial

Fast-track Blood Test for Suspected Fever by Deficiency of a Kind of White Blood Cells As Main Defense Against Infection

Unknown status·TThe University of Hong Kong·Phase 4·NCT05393505·344 enrolled

Periprosthetic Joint Infection1 trial

Prospective Randomized Evaluation of Emerging Novel Treatments for Infection Prophylaxis in Total Joint Replacement: A Pilot Study

Completed·HHamilton Health Sciences Corporation·Phase 3·NCT05084378·495 enrolled

Prostate Cancer1 trial

A Randomized Trial of Modifications to Radical Prostatectomy

Active, not recruiting·MMemorial Sloan Kettering Cancer Center·Phase 3·NCT01407263·3,204 enrolled

Unspecified2 trials

NextGen - Clinical Implication of Next Generation Sequencing

Recruiting·WWake Forest University Health Sciences·Phase 4·NCT05206500·100 enrolled

Randomized Trial Comparing Transperineal vs. Transrectal MRI-targeted Prostate Biopsy; Randomized Controlled Trial Assessing Transperineal Prostate Biopsy to Reduce Infection Complications

Completed·WWeill Medical College of Cornell University·Preclinical·NCT04815876·1,040 enrolled

Sources

References

[1]
ClinicalTrials.gov — 79 trial records for Antibiotic. U.S. National Library of Medicine, National Institutes of Health.
[2]
ChEMBL — Antibiotic compound record. European Bioinformatics Institute (EMBL-EBI).
[3]
Open Targets Platform — Drug–disease associations for Antibiotic. EMBL-EBI & Wellcome Sanger Institute.
[4]
SEC EDGAR — Pfizer company filings. U.S. Securities and Exchange Commission.

Details

Drug Info

Quick Facts

Modality: Small molecule[2]
Highest Phase: Phase 3[1]
Company: Pfizer

Antibiotic

Status by Indication[3][1]

Competitive Landscape

Expected Milestones

Q1 2027

Q3 2027

Q4 2027

Q2 2028

Trials by Indication[1]

Antibiotic Prophylaxis8 trials

Antibiotics7 trials

Antibiotic2 trials

Diverticulitis2 trials

Gut Microbiome2 trials

Pneumonia2 trials

Third Molar Surgery2 trials

Infections2 trials

Randomized Controlled Trial2 trials

Appendicitis1 trial

Chronic Obstructive Pulmonary Disease1 trial

Child Health1 trial

Urinary Tract Infection1 trial

Acute Myeloid Leukemia1 trial

Sepsis1 trial

Pregnancy1 trial

Pediatric Patients1 trial

MPA1 trial

Immunology1 trial

TED1 trial

Complicated Appendicitis1 trial

Ciprofloxacin1 trial

Ventilator-Associated Pneumonia1 trial

Pyelonephritis1 trial

Trial1 trial

Cystic Fibrosis1 trial

Mohs Micrographic Surgery1 trial

Virus Diseases1 trial

Miscarriage1 trial

Outcome1 trial

Safety and Efficacy1 trial

Bacterial Vaginosis1 trial

Spine Surgery1 trial

Breast Reconstruction1 trial

Granuloma1 trial

Multiple Myeloma1 trial

Wound Healing1 trial

Microbiota1 trial

Laparoscopic Cholecystectomy1 trial

Premature rupture of membranes1 trial

Cardiac Arrest1 trial

Indocyanine Green (ICG)1 trial

Intensive Care Unit1 trial

Clinical Trial1 trial

Abscess1 trial

Cervicitis1 trial

Sinusitis1 trial

Prophylaxis1 trial

Anticoagulation1 trial

Neonatal sepsis1 trial

Preoperative1 trial

Tonsillectomy1 trial

Central Nervous System1 trial

Antibiotic Therapy1 trial

Infection1 trial

Periprosthetic Joint Infection1 trial

Prostate Cancer1 trial

Unspecified2 trials

References

Drug Info

Quick Facts

Related News