Combination drug

Phase 3Small molecule

Bayer

Combination drug is one of 122 small molecule programs targeting Low back pain. It is currently in Phase 3.

Indications

Total Trials

Active Trials

121

Competitors

Pipeline

Status by Indication[3][1]

Indication

Low Back PainActive, not recruiting

Alcoholic Fatty Liver DiseaseActive, not recruiting

Pancreatic CancerActive, not recruiting

Hematological MalignanciesRecruiting

Low Back PainPhase 3

Active, not recruiting

Alcoholic Fatty Liver DiseasePhase 3

Active, not recruiting

Pancreatic CancerPhase 2

Active, not recruiting

Hematological MalignanciesPreclinical

Recruiting

Competition

Competitive Landscape

1063 competitors in Pancreatic Cancer

#DrugCompanyPhaseTrials

Combination drug

Bayer

Phase 3

1 2

Medrol

Pfizer

Preclinical

1 3

Byetta

AstraZeneca

Preclinical

1 4

MS Contin

Merck & Co.

Preclinical

1 5

Active Comparator

Moderna

Preclinical

1 6

LDE225

Novartis

Preclinical

1 7

Sulfonylureas

Eli Lilly

Preclinical

1 8

Chemotherapy Agents

Takeda

Preclinical

1 9

Secretin-Ferring

Ferring

Preclinical

1 10

Biguanides

Eli Lilly

Preclinical

Ranked by pipeline maturity and clinical activity. Current drug highlighted in teal.

Timeline

Expected Milestones

Q1 2030

Phase 3Recruiting

Recurrent Rectal Cancer

NCT04389086

Q4 2030

PreclinicalRecruiting

Hematological Malignancies

NCT07220616

Clinical

Trials by Indication[1]

Recurrent Rectal Cancer1 trial

Induction Chemotherapy for Locally Recurrent Rectal Cancer

Recruiting·CCatharina Ziekenhuis Eindhoven·Phase 3·NCT04389086·364 enrolled

Clopidogrel1 trial

Clopidogrel Aspirin Therapy (CAT) Versus Apixiban Aspirin Therapy (AAT) After Lower Limb Revascularization

Completed·MMansoura University·Phase 1/2·NCT04168398·1,536 enrolled

Pancreatic Cancer1 trial

Combination of Anti-PD-1 Antibody and Chemotherapy in Metastatic Pancreatic Cancer

Completed·ZZhejiang University·Phase 2·NCT03977272·110 enrolled

Treatment1 trial

Roll-over Study to Continue Treatment With the Investigational Drug Rogaratinib and to Further Test Its Safety

Completed· Bayer logo

Bayer·Phase 2·NCT04125693·1 enrolled

Alcoholic Fatty Liver Disease1 trial

An Investigator Initiated Prospective, Four Arms Randomized Comparative Study of Efficacy and Safety of Saroglitazar, Vitamin E and Life Style Modification in Patients With Nonalcoholic Fatty Liver Disease (NAFLD)/ Non-alcoholic Steatohepatitis (NASH)

Unknown status·—·Phase 3·NCT04193982·250 enrolled

3 more indications

Low back pain1 trial

A Two-Arm Study Comparing the Analgesic Efficacy and Safety of Acetaminophen and Tramadol Combination BID Versus Placebo for the Treatment of Acute Low Back Pain

Completed·LLabopharm Inc.·Phase 3·NCT00643383·277 enrolled

Solid Tumors1 trial

Niraparib and Dostarlimab in HRD Solid Tumors

Unknown status·WWest Cancer Center·Phase 2·NCT04983745·30 enrolled

Hematological Malignancies1 trial

A Phase 1/2, Multicenter, Open-Label, Multi-Cohort, First-in Human Trial of DS3790a, a DXd-ADC Targeting CD37, for Hematological Malignancies

Recruiting· Daiichi Sankyo logo

Daiichi Sankyo·Preclinical·NCT07220616·420 enrolled

Sources

References

[1]
ClinicalTrials.gov — 8 trial records for Combination drug. U.S. National Library of Medicine, National Institutes of Health.
[2]
ChEMBL — Combination drug compound record. European Bioinformatics Institute (EMBL-EBI).
[3]
Open Targets Platform — Drug–disease associations for Combination drug. EMBL-EBI & Wellcome Sanger Institute.
[4]
SEC EDGAR — Bayer company filings. U.S. Securities and Exchange Commission.

Details

Drug Info

Quick Facts

Modality: Small molecule[2]
Highest Phase: Phase 3[1]
Company: Bayer

Combination drug

Status by Indication[3][1]

Competitive Landscape

Expected Milestones

Q1 2030

Q4 2030

Trials by Indication[1]

Recurrent Rectal Cancer1 trial

Clopidogrel1 trial

Pancreatic Cancer1 trial

Treatment1 trial

Alcoholic Fatty Liver Disease1 trial

Low back pain1 trial

Solid Tumors1 trial

Hematological Malignancies1 trial

References

Drug Info

Quick Facts

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