darunavir/ritonavir

Pipeline

Status by Indication[3][1]

Competition

Competitive Landscape

TuberculosisImmunodeficiency

297 competitors in Tuberculosis

#DrugCompanyPhaseTrials

1

Onbrez

Novartis

Phase 3

12

Levaquin

WWim Janssens

Phase 3

83

Bayer Aspirin

Bayer

Phase 3

—4

Rayos

RRoxane Laboratories

Phase 3

15

Pyridoxine Hydrochloride

NNational Institute of Allergy and Infectious Diseases (NIAID)

Phase 3

26

darunavir/ritonavir

GSK

Phase 3

27

Isoniazid and Rifapentine

CCenters for Disease Control and Prevention

Phase 3

18

Isoniazid for 9 Months

NNational Taiwan University Hospital

Phase 3

19

Tebrazid

AAdvancing Clinical Therapeutics Globally for HIV/AIDS and Other Infections

Preclinical

2210

ESAT6-CFP10

Anhui Zhifei Longcom Biologic Pharmacy Co., Ltd.

Phase 3

3Show 19 more competitors

Ranked by pipeline maturity and clinical activity. Current drug highlighted in teal.

Timeline

Expected Milestones

Clinical

Trials by Indication[1]

Interaction5 trials

Drug Interaction Study of Darunavir/Ritonavir and Lopinavir/Ritonavir on GSK2248761 PK and CYP450 Probe Drugs

Completed·GSK·Phase 1·NCT00920088·24 enrolled

Interaction Between Etravirine or Darunavir/Ritonavir and Artemether / Lumefantrine

Completed·Johnson & Johnson·Phase 1·NCT01876966·33 enrolled

Darunavir and Rilpivirine Interactions With Levonorgestrel Implant

Unknown status·MMakerere University·Phase 2·NCT03589027·60 enrolled

Show 2 more trials

Drug-drug Interaction (DDI) Study of GSK3640254 With Darunavir/Ritonavir (DRV/RTV) and Etravirine (ETR)

Completed·GSK·Phase 1·NCT04630002·54 enrolled

Drug-Drug Interaction of Darunavir/Ritonavir on Pitavastatin

Completed·KKowa Research Institute, Inc.·Phase 4·NCT01422369·28 enrolled

Tenofovir3 trials

Study to Evaluate Darunavir/Ritonavir + Lamivudine Versus Continuing With Darunavir/Ritonavir + Tenofovir/Emtricitabine or Abacavir/Lamivudine in HIV Infected Subject

Completed·FFundacion SEIMC-GESIDA·Phase 4·NCT02159599·249 enrolled

Darunavir/Ritonavir + Lamivudine Versus Darunavir/Ritonavir +Emtricitabine/Tenofovir in Naïve HIV-1 Infected Subjects

Completed·FFundación Huésped·Phase 4·NCT02770508·145 enrolled

Comparative Trial Of Maraviroc Versus Emtricitabine/Tenofovir Both With Darunavir/Ritonavir In Antiretroviral-Naive Patients Infected With CCR5 Tropic HIV 1

Terminated·GSK·Phase 3·NCT01345630·813 enrolled

Treatment2 trials

Maraviroc (Celsentri) With Raltegravir and Darunavir/Ritonavir for the Treatment of Triple Class Failure in Adult HIV-1 Infected Patients

Unknown status·FFundación Huésped·Phase 4·NCT01013987·60 enrolled

An Immunologic Study of Treatment-Naive HIV Patients Starting a Darunavir/Ritonavir- or Efavirenz-Based HAART

Completed·Johnson & Johnson··NCT01541085·33 enrolled

HIV2 trials

Abacavir Pharmacokinetic Study in the Absence/Presence of Darunavir/Ritonavir or Raltegravir in HIV-infected Subjects

Completed·SSt Stephens Aids Trust·Phase 1·NCT00765271·29 enrolled

Clinical Evaluation of Adjusted Doses of Darunavir/Ritonavir With Rifampicin in HIV-infected Volunteers

Terminated·UUniversity of Cape Town·Phase 1·NCT03892161·17 enrolled

Tuberculosis2 trials

Interaction of Buprenorphine With HIV Medications and Tuberculosis Medications

Completed·UUniversity of California, San Francisco·Phase 1·NCT00877591·63 enrolled

Pharmacokinetic Properties of Antiretroviral and Anti-Tuberculosis Drugs During Pregnancy and Postpartum

Completed·NNational Institute of Allergy and Infectious Diseases (NIAID)··NCT04518228·205 enrolled

7 more indications

Resistance1 trial

Ndovu RCT: Investing the Optimal Management of Dolutegravir Resistance

Recruiting·UUniversity of Nairobi·Phase 3·NCT06747507·392 enrolled

Effectiveness1 trial

Safety and Effectiveness of Raltegravir Plus Darunavir/Ritonavir in Treatment-Naive HIV-Infected Adults

Completed·AAdvancing Clinical Therapeutics Globally for HIV/AIDS and Other Infections·Phase 2·NCT00830804·113 enrolled

Efficacy and Safety1 trial

Clinical Study to Evaluate the Efficacy and Safety of Lopinavir/Ritonavir Monotherapy Versus Darunavir/Ritonavir Monotherapies as Simplification Switching Strategies of PI/NNRTI-Triple Therapy Based-Regimens

Completed·GGermans Trias i Pujol Hospital·Phase 4·NCT00994344·73 enrolled

Monotherapy1 trial

Darunavir Levels, Virological Efficacy, Proviral ADN and Resistances in Patients on Darunavir/Ritonavir Monotherapy

Completed·HHospitales Universitarios Virgen del Rocío··NCT01606722·150 enrolled

Drug1 trial

Study to Determine the Pharmacokinetic Behavior of Antiretroviral Drugs in Patients Infected by HIV

Completed·GGermans Trias i Pujol Hospital·Phase 1·NCT00307502·675 enrolled

Clinical Trial1 trial

Clinical Trial to Assess the Efficacy of Darunavir/Ritonavir (DRV/r), Etravirine (ETV) and Raltegravir (MK-0518) in HIV Patients With Resistant Viruses

Completed·FFrench National Agency for Research on AIDS and Viral Hepatitis·Phase 2·NCT00460382·103 enrolled

Immunodeficiency1 trial

Human Immunodeficiency Virus (HIV) Postexposure Prophylaxis (PEP) With Darunavir/Ritonavir (DRV/r)

Completed·Johnson & Johnson·Phase 3·NCT01516970·312 enrolled

Details

Drug Info

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