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DUOC-01

Phase 1Biologic

JJoanne Kurtzberg, MD

DUOC-01 is one of 38 biologic programs targeting Metabolic Disease. It is currently in Phase 1.

2

Indications

2

Total Trials

1

Active Trials

37

Competitors

Pipeline

Status by Indication[3][1]

Indication

Metabolic DiseaseActive, not recruiting

Primary Progressive Multiple SclerosisActive, not recruiting

Metabolic DiseasePhase 1

Active, not recruiting

Primary Progressive Multiple SclerosisPhase 1

Active, not recruiting

Competition

Competitive Landscape

27 competitors in Metabolic Disease

#DrugCompanyPhaseTrials

Tivicay

Onglyza

Farxiga

Avandia

Alnylam Pharmaceuticals

Altoprev

CCidara Therapeutics Inc., a subsidiary of Merck & Co., Inc. (Rahway, New Jersey USA)

Glucophage

Tricor

Crestor

Neoral

Medrol

Ranked by pipeline maturity and clinical activity. Current drug highlighted in teal.

Timeline

Expected Milestones

Q4 2026

Phase 1Recruiting

Metabolic Disease

NCT02254863

Clinical

Trials by Indication[1]

Metabolic Disease1 trial

UCB Transplant of Inherited Metabolic Diseases With Administration of Intrathecal UCB Derived Oligodendrocyte-Like Cells

Recruiting·JJoanne Kurtzberg, MD·Phase 1·NCT02254863·40 enrolled

Primary Progressive Multiple Sclerosis1 trial

Intrathecal Administration of DUOC-01 in Adults With Primary Progressive Multiple Sclerosis

Completed·JJoanne Kurtzberg, MD·Phase 1·NCT04943289·20 enrolled

Sources

References

[1]
ClinicalTrials.gov — 2 trial records for DUOC-01. U.S. National Library of Medicine, National Institutes of Health.
[2]
ChEMBL — DUOC-01 compound record. European Bioinformatics Institute (EMBL-EBI).
[3]
Open Targets Platform — Drug–disease associations for DUOC-01. EMBL-EBI & Wellcome Sanger Institute.
[4]
SEC EDGAR — Joanne Kurtzberg, MD company filings. U.S. Securities and Exchange Commission.

Details

Drug Info

Quick Facts

Modality: Biologic[2]
Highest Phase: Phase 1[1]
Company: JJoanne Kurtzberg, MD

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