DUOC-01

Phase 1Biologic

JJoanne Kurtzberg, MD

DUOC-01 is one of 6 biologic programs targeting Adrenoleukodystrophy. It is currently in Phase 1.

Indications

Total Trials

Active Trials

Competitors

Pipeline

Status by Indication[3][1]

Indication

AdrenoleukodystrophyRecruiting

AdrenoleukodystrophyPhase 1

Recruiting

Competition

Competitive Landscape

6 competitors in Adrenoleukodystrophy

#DrugCompanyPhaseTrials

Mirapex

Boehringer Ingelheim

Approved

1 2

Cytoxan

BBaxter Healthcare Corporation

Busulfex

Thalomid

1 5

DUOC-01

JJoanne Kurtzberg, MD

Phase 1

1 6

Interferon-Beta

Biogen

Preclinical

Ranked by pipeline maturity and clinical activity. Current drug highlighted in teal.

Timeline

Expected Milestones

Q4 2027

Phase 1Recruiting

Adrenoleukodystrophy

NCT02254863

Clinical

Trials by Indication[1]

Primary Progressive Multiple Sclerosis1 trial

Intrathecal Administration of DUOC-01 in Adults With Primary Progressive Multiple Sclerosis

Completed·JJoanne Kurtzberg, MD·Phase 1·NCT04943289·20 enrolled

Adrenoleukodystrophy1 trial

Augmentation of Umbilical Cord Blood Transplantation for Inherited Metabolic Diseases With Intrathecal Administration of Human Umbilical Cord Blood-Derived Oligodendrocyte-Like Cells

Recruiting·JJoanne Kurtzberg, MD·Phase 1·NCT02254863·40 enrolled

Sources

References

[1]
ClinicalTrials.gov — 2 trial records for DUOC-01. U.S. National Library of Medicine, National Institutes of Health.
[2]
ChEMBL — DUOC-01 compound record. European Bioinformatics Institute (EMBL-EBI).
[3]
Open Targets Platform — Drug–disease associations for DUOC-01. EMBL-EBI & Wellcome Sanger Institute.
[4]
SEC EDGAR — Joanne Kurtzberg, MD company filings. U.S. Securities and Exchange Commission.

Details

Drug Info

Quick Facts

Modality: Biologic[2]
Highest Phase: Phase 1[1]
Company: JJoanne Kurtzberg, MD

DUOC-01

Status by Indication[3][1]

Competitive Landscape

Expected Milestones

Q4 2027

Trials by Indication[1]

Primary Progressive Multiple Sclerosis1 trial

Adrenoleukodystrophy1 trial

References

Drug Info

Quick Facts

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