Lusedra

(Fospropofol)

ApprovedSmall molecule

Eisai

Lusedra is one of 3 small molecule programs targeting Sedation. It is currently in Approved.

Indications

Total Trials

Active Trials

Competitors

FDA Application

NDA/BLA/ANDA regulatory filings

Pipeline

Status by Indication[3][1]

Indication

Laparoscopic SurgeryRecruiting

Laparoscopic SurgeryApproved

Recruiting

Competition

Competitive Landscape

2 competitors in Laparoscopic Surgery

#DrugCompanyPhaseTrials

Lusedra

Eisai

Approved

1 2

Intropin

Pfizer

Preclinical

1 3

Ramosetron

Astellas

Preclinical

Ranked by pipeline maturity and clinical activity. Current drug highlighted in teal.

Clinical

Trials by Indication[1]

Anesthesia2 trials

ED90 of Fospropofol Disodium in Induction and Maintenance of Anesthesia

Completed·TTongji Hospital·Phase 4·NCT06344325·330 enrolled

Comparison of AQUAVAN® Injection to DISOPRIVAN® Injectable Emulsion for Anesthesia During Coronary Artery Surgery

Completed· Eisai logo

Eisai·Phase 2·NCT00209521·16 enrolled

Sedation1 trial

Fospropofol for Sedation During Elective Awake Intubation

Withdrawn·TThe Cleveland Clinic·N/A·NCT01289483

Invasive Mechanical Ventilation1 trial

Safety and Efficacy of Fospropofol vs Propofol During Invasive Mechanical Ventilation.

Unknown status·HHenan Provincial People's Hospital·N/A·NCT06261996·200 enrolled

Laparoscopic Surgery1 trial

Efficacy and Safety of Fospropofol in Adult Laparoscopic Surgery: A Clinical Trial

Recruiting·HHui Xu·Phase 4·NCT06573489·373 enrolled

Prospective1 trial

Preventing Propofol Injection Pain: Prospective Randomized Trial Comparing Propofol Versus Fospropofol

Completed·NNYU Langone Health·Phase 4·NCT01401049·116 enrolled

Regulatory

FDA Approval Timeline[4]

Dec 12, 2008

LUSEDRA

NDA NDA022244

Sources

References

[1]
ClinicalTrials.gov — 6 trial records for Fospropofol. U.S. National Library of Medicine, National Institutes of Health.
[2]
ChEMBL — Fospropofol compound record. European Bioinformatics Institute (EMBL-EBI).
[3]
Open Targets Platform — Drug–disease associations for Fospropofol. EMBL-EBI & Wellcome Sanger Institute.
[4]
OpenFDA — FDA approval records (NDA NDA022244). U.S. Food & Drug Administration.
[5]
SEC EDGAR — Eisai company filings. U.S. Securities and Exchange Commission.

Details

Drug Info

Quick Facts

Modality: Small molecule[2]
Highest Phase: Approved[1]
Company: Eisai

Lusedra

Status by Indication[3][1]

Competitive Landscape

Trials by Indication[1]

Anesthesia2 trials

Sedation1 trial

Invasive Mechanical Ventilation1 trial

Laparoscopic Surgery1 trial

Prospective1 trial

FDA Approval Timeline[4]

References

Drug Info

Quick Facts

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