Generic Ingenol Mebutate

Phase 3Small molecule

AActavis Inc.

Generic Ingenol Mebutate is one of 80 small molecule programs targeting Rosacea. It is currently in Phase 3.

Indications

Total Trials

Active Trials

Competitors

Pipeline

Status by Indication[3][1]

Indication

RosaceaActive, not recruiting

Atrophic VaginitisActive, not recruiting

AsthmaActive, not recruiting

Actinic KeratosisActive, not recruiting

RosaceaPhase 3

Active, not recruiting

Atrophic VaginitisPhase 3

Active, not recruiting

AsthmaPhase 3

Active, not recruiting

Actinic KeratosisPhase 3

Active, not recruiting

Competition

Competitive Landscape

1050 competitors in Asthma

#DrugCompanyPhaseTrials

Generic Ingenol Mebutate

AActavis Inc.

Phase 3

2 2

Veramyst

GSK

Preclinical

46 3

Cinqair

Teva

Preclinical

13 4

Asmanex

Novartis

Preclinical

5 5

Celexa

AbbVie

Preclinical

1 6

Spiriva

Boehringer Ingelheim

Preclinical

8 7

Qvar

Chiesi Farmaceutici S.p.A.

Preclinical

8 8

Arcoxia

Symbicort

6 10

Decadron

QQuince Therapeutics S.p.A.

Preclinical

Ranked by pipeline maturity and clinical activity. Current drug highlighted in teal.

Clinical

Trials by Indication[1]

Actinic Keratosis3 trials

An Equivalence Study of Generic Ingenol Mebutate Gel 0.015% and Picato Gel 0.015% in Subjects With Actinic Keratosis

Completed·AActavis Inc.·Phase 3·NCT03200912·507 enrolled

Multicenter, Double-blind, Placebo Controlled Comparing Test Fluorouracil Cream to Carac Cream in Actinic Keratosis

Completed·AActavis Inc.·Phase 3·NCT02616601·422 enrolled

A Study of Equivalence of Generic Ingenol Mebutate Gel 0.05% and Picato Gel 0.05% in Subjects With Actinic Keratosis

Completed·AActavis Inc.·Phase 3·NCT02654769·441 enrolled

Asthma2 trials

Randomized, Placebo-controlled Study Comparing Efficacy of Fluticasone/Salmeterol Combination to Advair in Asthmatics

Withdrawn·AActavis Inc.·Phase 3·NCT02496715

Randomized, Placebo-Controlled, Multidose, Study Comparing Generic Budesonide/Formoterol Fumarate Dihydrate to Symbicort® in Asthmatic Participants

Completed·AActavis Inc.·Phase 3·NCT02495168·1,714 enrolled

POI1 trial

Clinical Endpoint Study of Ivermectin 0.5% Lotion

Completed·AActavis Inc.·Phase 3·NCT03301649·905 enrolled

Rosacea1 trial

A Study to Evaluate Safety and Equivalence of Generic Azelaic Acid Foam and Finacea® Foam in Participants With Rosacea

Completed·AActavis Inc.·Phase 3·NCT03287791·924 enrolled

Atrophic Vaginitis1 trial

Study to Evaluate Equivalence of Estradiol Vaginal Cream 0.01% to Estrace® Cream 0.01% in Atrophic Vaginitis

Completed·AActavis Inc.·Phase 3·NCT03294538·663 enrolled

Sources

References

[1]
ClinicalTrials.gov — 8 trial records for Generic Ingenol Mebutate. U.S. National Library of Medicine, National Institutes of Health.
[2]
ChEMBL — Generic Ingenol Mebutate compound record. European Bioinformatics Institute (EMBL-EBI).
[3]
Open Targets Platform — Drug–disease associations for Generic Ingenol Mebutate. EMBL-EBI & Wellcome Sanger Institute.
[4]
SEC EDGAR — Actavis Inc. company filings. U.S. Securities and Exchange Commission.

Details

Drug Info

Quick Facts

Modality: Small molecule[2]
Highest Phase: Phase 3[1]
Company: AActavis Inc.

Generic Ingenol Mebutate

Status by Indication[3][1]

Competitive Landscape

Trials by Indication[1]

Actinic Keratosis3 trials

Asthma2 trials

POI1 trial

Rosacea1 trial

Atrophic Vaginitis1 trial

References

Drug Info

Quick Facts

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