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HSK3486

Phase 2Small molecule

SSichuan Haisco Pharmaceutical Group Co., Ltd

1

Indications

28

Total Trials

0

Active Trials

0

Competitors

Clinical

Trials by Indication[1]

Efficacy and Safety7 trials

A Trial Evaluating the Efficacy and Safety of HSK3486 Injectable Emulsion for the Induction of General Anesthesia in Elective Surgery Subjects

Completed·SSichuan Haisco Pharmaceutical Group Co., Ltd·Phase 3·NCT03808844·178 enrolled

A Clinical Trial Evaluating the Efficacy and Safety of HSK3486 Injectable Emulsion in Elective Surgery Patients

Completed·SSichuan Haisco Pharmaceutical Group Co., Ltd·Phase 2·NCT04048811·46 enrolled

A Study to Evaluate the Efficacy and Safety of HSK3486 in the Induction of General Anesthesia

Completed· Haisco Pharmaceutical Group Co., Ltd. logo

Haisco Pharmaceutical Group Co., Ltd.·Phase 3·NCT04511728·129 enrolled

Show 4 more trials

Efficacy and Safety of HSK3486 Compared to Propofol for Adults Undergoing Elective Surgery With General Anesthesia

Completed·HHaisco-USA Pharmaceuticals, Inc.·Phase 3·NCT05478174·400 enrolled

A Phase IIa Study Investigating the Tolerance, Efficacy and Safety of HSK3486

Completed·SSichuan Haisco Pharmaceutical Group Co., Ltd·Phase 2·NCT03698617·114 enrolled

A Study Evaluating the Efficacy and Safety of HSK3486

Completed·SSichuan Haisco Pharmaceutical Group Co., Ltd·Phase 2·NCT03709056·94 enrolled

Efficacy and Safety of HSK3486 Compared to Propofol in Induction of General Anesthesia in Adults Having Elective Surgery

Completed·HHaisco-USA Pharmaceuticals, Inc.·Phase 3·NCT04711837·255 enrolled

Sedation3 trials

A Clinical Study Evaluating Sedation of Intravenous Administration of HSK3486 in ICU Patients Undergoing Long-Term Mechanical Ventilation

Completed· Haisco Pharmaceutical Group Co., Ltd. logo

Haisco Pharmaceutical Group Co., Ltd.·Phase 2·NCT04669821·20 enrolled

A Study Evaluating Sedation of Intravenous Administration of HSK3486 Injectable Emulsion in ICU Patients Undergoing Mechanical Ventilation

Completed· Haisco Pharmaceutical Group Co., Ltd. logo

Haisco Pharmaceutical Group Co., Ltd.·Phase 3·NCT04620031·135 enrolled

A Phase III Study Evaluating The Efficacy and Safety of HSK3486 for Sedation or Anesthesia

Completed·SSichuan Haisco Pharmaceutical Group Co., Ltd·Phase 3·NCT03674008·280 enrolled

Tics3 trials

A Study Evaluating Safety, Tolerability, and Pharmacokinetics/Pharmacodynamics of Single IV Dose of HSK3486 Injectable Emulsion in Healthy Subjects.

Completed·SSichuan Haisco Pharmaceutical Group Co., Ltd·Phase 1·NCT03773835·24 enrolled

A Study Evaluating the Safety, Pharmacodynamics and Pharmacokinetics of HSK3486 in Healthy Subjects.

Completed·SSichuan Haisco Pharmaceutical Group Co., Ltd·Phase 1·NCT04033939·48 enrolled

A Study Evaluating the Safety and Pharmacokinetics/Pharmacodynamics of HSK3486

Completed·SSichuan Haisco Pharmaceutical Group Co., Ltd·Phase 1·NCT03745625·16 enrolled

Central Nervous System2 trials

Part 1: Dose-Finding of HSK3486 Injection In Nondependent, Recreational Central Nervous System Depressant Users

Completed·HHaisco-USA Pharmaceuticals, Inc.·Phase 1·NCT07404306·43 enrolled

Dose-Finding and Human Abuse Potential Study Of HSK3486 Injection In Nondependent, Recreational Central Nervous System Depressant Users

Completed·HHaisco-USA Pharmaceuticals, Inc.·Phase 1·NCT05614544·42 enrolled

Adult2 trials

A Study Evaluating the Mass Balance of [14C]HSK3486 Emulsion Injection in Healthy Adults.

Completed·SSichuan Haisco Pharmaceutical Group Co., Ltd·Phase 1·NCT03751956·6 enrolled

A Study Evaluating the Mass Balance of Micro-dose[14C]HSK3486 Emulsion Injection in Healthy Adults

Withdrawn·SSichuan Haisco Pharmaceutical Group Co., Ltd·Phase 1·NCT03751969

10 more indications

Interaction2 trials

A Study Evaluating Drug-Drug Interaction (DDI) Between HSK3486 Injectable Emulsion and Voriconazole Tablets

Completed·SSichuan Haisco Pharmaceutical Group Co., Ltd·Phase 1·NCT04145583·16 enrolled

A Study Evaluating Drug-Drug Interaction (DDI) Between HSK3486 Injectable Emulsion and Rifampin Capsules

Completed·SSichuan Haisco Pharmaceutical Group Co., Ltd·Phase 1·NCT03758469·16 enrolled

Cardiac Repolarization1 trial

Effects of HSK3486 on Cardiac Repolarization in Health Subjects (TQT)

Completed·HHaisco-USA Pharmaceuticals, Inc.·Phase 1·NCT06795204·48 enrolled

Female1 trial

Evaluating the Safety, Pharmacodynamics and Pharmacokinetics of HSK3486 in Healthy Female Subjects.

Completed·SSichuan Haisco Pharmaceutical Group Co., Ltd·Phase 1·NCT04037657·25 enrolled

Fiberoptic Bronchoscopy1 trial

A Trial Evaluating the Efficacy and Safety of HSK3486 Injectable Emulsion in Subjects Undergoing Fiberoptic Bronchoscopy

Completed·SSichuan Haisco Pharmaceutical Group Co., Ltd·Phase 3·NCT04111159·267 enrolled

Impairment1 trial

Safety and Pharmacokinetics/Pharmacodynamics of HSK3486 in Patients With Impairment Renal Functions

Completed·SSichuan Haisco Pharmaceutical Group Co., Ltd·Phase 1·NCT04142970·24 enrolled

Elderly1 trial

Safety and Pharmacokinetics/Pharmacodynamics of HSK3486 in Healthy Elderly Subjects

Completed·SSichuan Haisco Pharmaceutical Group Co., Ltd·Phase 1·NCT04197661·32 enrolled

Infusion1 trial

A Study Evaluating Pharmacodynamics, Pharmacokinetics, Safety and Tolerability of HSK3486 Single Bolus Dose Followed With a 30 Minute Constant Infusion in Healthy Male Subjects

Completed·SSichuan Haisco Pharmaceutical Group Co., Ltd·Phase 1·NCT04029766·13 enrolled

Efficacy1 trial

A Study Evaluating Tolerability, Efficacy, and Safety of HSK3486 Injectable Emulsion in Patients

Completed·SSichuan Haisco Pharmaceutical Group Co., Ltd·Phase 2·NCT03773042·64 enrolled

Safety and Efficacy1 trial

Safety and Efficacy of HSK3486 Compared to Propofol for Induction of General Anesthesia in Adults With Elective Surgery

Completed·HHaisco-USA Pharmaceuticals, Inc.·Phase 3·NCT05486416·465 enrolled

Hepatic Impairment1 trial

Safety and Pharmacokinetics/Pharmacodynamics of HSK3486 in Patients With Hepatic Impairment

Completed·SSichuan Haisco Pharmaceutical Group Co., Ltd·Phase 1·NCT04145596·24 enrolled

Sources

References

[1]
ClinicalTrials.gov — 28 trial records for HSK3486. U.S. National Library of Medicine, National Institutes of Health.
[2]
ChEMBL — HSK3486 compound record. European Bioinformatics Institute (EMBL-EBI).
[3]
Open Targets Platform — Drug–disease associations for HSK3486. EMBL-EBI & Wellcome Sanger Institute.
[4]
SEC EDGAR — Sichuan Haisco Pharmaceutical Group Co., Ltd company filings. U.S. Securities and Exchange Commission.

Details

Drug Info

Quick Facts

Modality: Small molecule[2]
Highest Phase: Phase 2[1]
Company: SSichuan Haisco Pharmaceutical Group Co., Ltd

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