Fanapt
(Iloperidone)ApprovedSmall molecule
Iloperidone is used to treat schizophrenia, a mental health condition where people may experience hallucinations, delusions, or disorganized thinking. It helps reduce these symptoms by affecting certain chemicals in the brain.[2] Fanapt is currently approved and in use across 8 indications[4].[1]
Fanapt is one of 266 small molecule programs targeting Bipolar I Disorder. It is currently in Approved.
8
Indications
23
Total Trials
3
Active Trials
265
Competitors
1
FDA Application
NDA/BLA/ANDA regulatory filings
9
Patents
Pipeline
Status by Indication[4][1]
Indication
Competition
Competitive Landscape
583 competitors in Schizophrenia
#DrugCompanyPhaseTrials
1Fanapt
VVanda Pharmaceuticals
Approved
Celexa
AbbViePreclinical
Ozempic
Novo NordiskPreclinical
Resotran
TakedaPreclinical
Zocor
OOrganon and Co
Preclinical
Depakote
AbbViePreclinical
Lunesta
Akero TherapeuticsPreclinical
Inversine
TTargacept Inc.
Preclinical
Vivarin
HHikma Pharmaceuticals LLC
Preclinical
Compazine
GGlaxo Dba Glaxosmithkline
Preclinical
Ranked by pipeline maturity and clinical activity. Current drug highlighted in teal.
Timeline
Expected Milestones
Clinical
Trials by Indication[1]
Schizophrenia9 trials
Show 6 more trials
Adolescent2 trials
Bipolar I Disorder2 trials
8 more indications
Tics1 trial
Major Depressive Disorder1 trial
Iloperidone Augmentation of SSRIs for Patients With Major Depressive Disorder With Residual Anger and Irritability
Completed·—·Phase 4·NCT01464229·20 enrolled
Olanzapine1 trial
Liver Disease1 trial
Bipolar Disorder1 trial
Iloperidone in Mixed States of Bipolar Disorder
Completed·TThe University of Texas Health Science Center at San Antonio·Phase 4·NCT02413918·41 enrolled
Post-Traumatic Stress Disorder, PTSD1 trial
Regulatory
FDA Approval Timeline[5]
May 6, 2009
FANAPT
NDA NDA022192
Sources
References
- [1]
- [2]MedlinePlus Drug Information — Fanapt drug information. U.S. National Library of Medicine, National Institutes of Health.
- [3]
- [4]Open Targets Platform — Drug–disease associations for Iloperidone. EMBL-EBI & Wellcome Sanger Institute.
- [5]
- [6]FDA Orange Book — Patent and exclusivity data for Fanapt. U.S. Food & Drug Administration.
- [7]
Details
Drug Info
Quick Facts
- Mechanism of Action
- Dopamine D2 Receptor Antagonist; Serotonin 2a (5-Ht2a) Receptor Antagonist[3]
- Modality
- Small molecule[3]
- Highest Phase
- Approved[1]
- Company
- VVanda Pharmaceuticals