Intravenous thrombolysis
Phase 3Small molecule
Intravenous thrombolysis is one of 108 small molecule programs targeting Stroke. It is currently in Phase 3.
5
Indications
16
Total Trials
9
Active Trials
107
Competitors
Pipeline
Status by Indication[3][1]
Indication
Competition
Competitive Landscape
147 competitors in Stroke
#DrugCompanyPhaseTrials
1Intravenous thrombolysis
SSecond Affiliated Hospital, School of Medicine, Zhejiang University
Phase 3
Butylphthalide
PPeking Union Medical College Hospital
Phase 3
Zometa
PfizerPreclinical
Savella
AbbViePreclinical
Proamatine
TakedaPreclinical
Repatha
AmgenPreclinical
Zantac 150
CChattem
Preclinical
Alka-Seltzer
AAbbott
Preclinical
Haldol
DDePuy Orthopaedics
Preclinical
Periactin
CCidara Therapeutics Inc., a subsidiary of Merck & Co., Inc. (Rahway, New Jersey USA)
Preclinical
Ranked by pipeline maturity and clinical activity. Current drug highlighted in teal.
Timeline
Expected Milestones
Clinical
Trials by Indication[1]
Ischemic stroke6 trials
Intravenous Thrombolysis in Acute Ischemic Stroke with Active Cancer
Not yet recruiting·SSecond Affiliated Hospital, School of Medicine, Zhejiang University·Phase 3·NCT06841965·280 enrolled
Intra-arterial Hypothermic Magnesium Sulfate Infusion in Combination with Endovascular Thrombectomy in Acute Ischemic Stroke
Not yet recruiting·—·Phase 1·NCT06760195·6 enrolled
Show 3 more trials
Intravenous Thrombolytic Therapy for Acute Ischemic Stroke Patients with Low NIHSS and Non-disabling Deficits
Not yet recruiting·SSecond Affiliated Hospital, School of Medicine, Zhejiang University·Phase 4·NCT06115070·390 enrolled
Stroke2 trials
Venous thrombosis1 trial
Intravenous Thrombosis and Patients with Prior Ischemic Stroke Within 3 Months
Not yet recruiting·SSecond Affiliated Hospital, School of Medicine, Zhejiang University·Phase 3·NCT06841978·306 enrolled
Thrombolysis1 trial
Intravenous Thrombolysis and NOAC
Recruiting·SSecond Affiliated Hospital, School of Medicine, Zhejiang University·Phase 3·NCT06749834·280 enrolled
Large Vessel Occlusion1 trial
Direct Intra-arterial Thrombectomy in Order to Revascularize AIS Patients With Large Vessel Occlusion Efficiently in Chinese Tertiary Hospitals
Completed·—·N/A·NCT03469206·656 enrolled
5 more indications
Endovascular Thrombectomy1 trial
Endovascular Thrombectomy With and Without Intravenous Thrombolysis in Extended Time Window
Unknown status·SSecond Affiliated Hospital, School of Medicine, Zhejiang University·Phase 3·NCT05634382·222 enrolled
Pulmonary Embolism1 trial
Stroke, Acute Ischemic1 trial
Basilar Artery Occlusion1 trial
Endovascular Thrombectomy Alone Versus Intravenous Thrombolysis Plus Endovascular Thrombectomy on Acute Basilar Artery Occlusion - a Multicenter, Randomized Controlled, Clinical Trial
Completed·TThe First Affiliated Hospital of University of Science and Technology of China·Phase 3·NCT05827042·338 enrolled
Sources
References
- [1]
- [2]
- [3]Open Targets Platform — Drug–disease associations for Intravenous thrombolysis. EMBL-EBI & Wellcome Sanger Institute.
- [4]
Details