Lidocaine Epinephrine

PreclinicalSmall molecule

KKythera Biopharmaceuticals

Lidocaine Epinephrine is one of 6 small molecule programs targeting Local Anesthesia. It is currently in Preclinical.

Indications

Total Trials

Active Trials

Competitors

Pipeline

Status by Indication[3][1]

Indication

Local AnesthesiaCompleted

ObstetricCompleted

Shoulder ArthroscopyCompleted

Local AnesthesiaPreclinical

Completed

ObstetricPreclinical

Completed

Shoulder ArthroscopyPreclinical

Completed

Competition

Competitive Landscape

4 competitors in Local Anesthesia

#DrugCompanyPhaseTrials

Ketalar

AAultman Health Foundation

Approved

1 2

Benadryl

PParkedale

Phase 3

1 3

Oraverse

NNovocol Pharmaceutical of Canada, Inc.

Phase 3

1 4

Lidocaine Epinephrine

KKythera Biopharmaceuticals

Preclinical

Ranked by pipeline maturity and clinical activity. Current drug highlighted in teal.

Clinical

Trials by Indication[1]

Local Anesthesia3 trials

The Effectiveness of Soft Tissue Vibration in Reducing Pain of Local Anesthesia Injection in Adult Dental Patients

Completed·RRiyadh Colleges of Dentistry and Pharmacy·N/A·NCT03839134·166 enrolled

The Effects of Injection Site Cooling and Solution Buffering on Perceived Pain During Local Anesthesia Administration

Withdrawn·NNicholas Bastidas·N/A·NCT04991597

WALANT Technique (Wide Awake Local Anesthesia No Tourniquet) for Carpal Tunnel Release.

Completed·CCMC Ambroise Paré·N/A·NCT04494100·60 enrolled

Complication1 trial

Use of Tranexamic Acid in Reduction of Post-Op Complications in Mohs Micrographic Surgery

Terminated·RRiley McLean·Phase 1·NCT04630886·34 enrolled

CAR1 trial

WALANT Versus Axillary Brachial Plexus Block in Carpal Tunnel Release

Completed·CCMC Ambroise Paré·N/A·NCT06040840·130 enrolled

After Cardiac Surgery1 trial

Pectoral Nerves Block to Relieve Post-sternotomy Pain After Cardiac Surgery

Withdrawn·NNYU Langone Health·N/A·NCT04282239

Radius Fracture1 trial

Ultrasound-guided Infraclavicular Block With Lidocaine or Ropivacaine for Closed Reduction of Distal Radius Fractures

Completed·NNordsjaellands Hospital·Phase 3·NCT06379490·67 enrolled

5 more indications

Shoulder Arthroscopy1 trial

Lidocaine Irrigation in Shoulder Arthroscopy

Completed·MMinia University·N/A·NCT05624957·50 enrolled

Opioid1 trial

Exparel Injection Effect on Postoperative Opioid Usage

Enrolling by invitation·UUniversity of Missouri-Columbia·Phase 1·NCT04085913·100 enrolled

Nerve Block1 trial

Combining Lidocaine and Ropivacaine for an Infraclavicular Brachial Plexus Nerve Block

Completed·NNordsjaellands Hospital·Phase 3·NCT06381622·78 enrolled

Obstetric1 trial

Alkalinization of Adrenalized Lidocaine in Extending Epidural Analgesia for Extremely Urgent Cesarean Section During Labor: a Randomized Controlled Trial.

Completed·UUniversity Hospital, Bordeaux·Preclinical·NCT05313256·65 enrolled

Unspecified1 trial

Patient Experience Study of Deoxycholic Acid Injection

Completed·KKythera Biopharmaceuticals·Phase 3·NCT02007434·84 enrolled

Sources

References

[1]
ClinicalTrials.gov — 12 trial records for Lidocaine Epinephrine. U.S. National Library of Medicine, National Institutes of Health.
[2]
ChEMBL — Lidocaine Epinephrine compound record. European Bioinformatics Institute (EMBL-EBI).
[3]
Open Targets Platform — Drug–disease associations for Lidocaine Epinephrine. EMBL-EBI & Wellcome Sanger Institute.
[4]
SEC EDGAR — Kythera Biopharmaceuticals company filings. U.S. Securities and Exchange Commission.

Details

Drug Info

Quick Facts

Modality: Small molecule[2]
Highest Phase: Preclinical[1]
Company: KKythera Biopharmaceuticals

Lidocaine Epinephrine

Status by Indication[3][1]

Competitive Landscape

Trials by Indication[1]

Local Anesthesia3 trials

Complication1 trial

CAR1 trial

After Cardiac Surgery1 trial

Radius Fracture1 trial

Shoulder Arthroscopy1 trial

Opioid1 trial

Nerve Block1 trial

Obstetric1 trial

Unspecified1 trial

References

Drug Info

Quick Facts

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