Lidocaine Epinephrine

Phase 3Small molecule

KKythera Biopharmaceuticals

Lidocaine Epinephrine is one of 24 small molecule programs targeting Complication. It is currently in Phase 3.

Indications

Total Trials

Active Trials

Competitors

Pipeline

Status by Indication[3][1]

Indication

Radius FractureActive, not recruiting

Radius FracturePhase 3

Active, not recruiting

Competition

Competitive Landscape

33 competitors in Radius Fracture

#DrugCompanyPhaseTrials

Toradol

Roche

Approved

1 2

Medrol

Pfizer

Approved

1 3

Decadron

AAspen Global Incorporated

Approved

3 4

Tylenol

KKenvue Brands

Approved

2 5

Advil

KKenvue Brands

Approved

2 6

Celebrex

PPhiladelphia Eye Associates

Approved

1 7

Xylocaine

MMEDRx USA, Inc.

Approved

—8

Precedex

MMcNeil Consumer & Specialty Pharmaceuticals, a Division of McNeil-PPC, Inc.

Approved

—9

Ketalar

AAultman Health Foundation

Arcoxia

Ranked by pipeline maturity and clinical activity. Current drug highlighted in teal.

Clinical

Trials by Indication[1]

Local Anesthesia3 trials

WALANT Technique (Wide Awake Local Anesthesia No Tourniquet) for Carpal Tunnel Release.

Completed·CCMC Ambroise Paré·N/A·NCT04494100·60 enrolled

The Effectiveness of Soft Tissue Vibration in Reducing Pain of Local Anesthesia Injection in Adult Dental Patients

Completed·RRiyadh Colleges of Dentistry and Pharmacy·N/A·NCT03839134·166 enrolled

The Effects of Injection Site Cooling and Solution Buffering on Perceived Pain During Local Anesthesia Administration

Withdrawn·NNicholas Bastidas·N/A·NCT04991597

Shoulder Arthroscopy1 trial

Lidocaine Irrigation in Shoulder Arthroscopy

Completed·MMinia University·N/A·NCT05624957·50 enrolled

Caesarean Delivery1 trial

Quick Epidural Top-up with Alkalinized Lidocaine for Emergent Caesarean Delivery

Completed·UUniversity Hospital, Bordeaux·Phase 2/3·NCT05313256·65 enrolled

Nerve Block1 trial

Combining Lidocaine and Ropivacaine for an Infraclavicular Brachial Plexus Nerve Block

Completed·NNordsjaellands Hospital·Phase 3·NCT06381622·78 enrolled

CAR1 trial

WALANT Versus Axillary Brachial Plexus Block in Carpal Tunnel Release

Completed·CCMC Ambroise Paré·N/A·NCT06040840·130 enrolled

5 more indications

After Cardiac Surgery1 trial

Pectoral Nerves Block to Relieve Post-sternotomy Pain After Cardiac Surgery

Withdrawn·NNYU Langone Health·N/A·NCT04282239

Complication1 trial

Use of Tranexamic Acid in Reduction of Post-Op Complications in Mohs Micrographic Surgery

Terminated·RRiley McLean·Phase 1·NCT04630886·34 enrolled

Radius Fracture1 trial

Ultrasound-guided Infraclavicular Block With Lidocaine or Ropivacaine for Closed Reduction of Distal Radius Fractures

Completed·NNordsjaellands Hospital·Phase 3·NCT06379490·67 enrolled

Opioid1 trial

Exparel Injection Effect on Postoperative Opioid Usage

Enrolling by invitation·UUniversity of Missouri-Columbia·Phase 1·NCT04085913·100 enrolled

Unspecified1 trial

Patient Experience Study of Deoxycholic Acid Injection

Completed·KKythera Biopharmaceuticals·Phase 3·NCT02007434·84 enrolled

Sources

References

[1]
ClinicalTrials.gov — 12 trial records for Lidocaine Epinephrine. U.S. National Library of Medicine, National Institutes of Health.
[2]
ChEMBL — Lidocaine Epinephrine compound record. European Bioinformatics Institute (EMBL-EBI).
[3]
Open Targets Platform — Drug–disease associations for Lidocaine Epinephrine. EMBL-EBI & Wellcome Sanger Institute.
[4]
SEC EDGAR — Kythera Biopharmaceuticals company filings. U.S. Securities and Exchange Commission.

Details

Drug Info

Quick Facts

Modality: Small molecule[2]
Highest Phase: Phase 3[1]
Company: KKythera Biopharmaceuticals

Lidocaine Epinephrine

Status by Indication[3][1]

Competitive Landscape

Trials by Indication[1]

Local Anesthesia3 trials

Shoulder Arthroscopy1 trial

Caesarean Delivery1 trial

Nerve Block1 trial

CAR1 trial

After Cardiac Surgery1 trial

Complication1 trial

Radius Fracture1 trial

Opioid1 trial

Unspecified1 trial

References

Drug Info

Quick Facts

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