Morphine hydrochloride

ApprovedSmall molecule

Morphine hydrochloride is one of 140 small molecule programs targeting Idiopathic Scoliosis. It is currently in Approved.

Indications

Total Trials

Active Trials

139

Competitors

Pipeline

Status by Indication[3][1]

Indication

Idiopathic ScoliosisActive, not recruiting

Chronic Obstructive Pulmonary DiseaseActive, not recruiting

Pulmonary FibrosisActive, not recruiting

Interstitial Lung DiseaseActive, not recruiting

Cesarean SectionActive, not recruiting

Idiopathic ScoliosisPhase 2

Active, not recruiting

Chronic Obstructive Pulmonary DiseasePhase 1/Phase 2

Active, not recruiting

Pulmonary FibrosisPhase 3

Active, not recruiting

Interstitial Lung DiseaseApproved

Active, not recruiting

Cesarean SectionPreclinical

Active, not recruiting

Competition

Competitive Landscape

557 competitors in Chronic Obstructive Pulmonary Disease

#DrugCompanyPhaseTrials

Morphine hydrochloride

Luye Pharma Group Ltd.

Approved

1 2

Veramyst

GSK

Preclinical

26 3

Flovent

GSK

Preclinical

6 4

Spiriva

Boehringer Ingelheim

Preclinical

15 5

Aclidinium Bromide

AstraZeneca

Preclinical

21 6

Formoterol Fumarate

AstraZeneca

Preclinical

11 7

Atrovent

Boehringer Ingelheim

Preclinical

5 8

Calciferol

Alnylam Pharmaceuticals

Preclinical

—9

Proventil

Mylan Pharmaceuticals Inc

Preclinical

3 10

Zoloft

VViatris Specialty LLC

Preclinical

Ranked by pipeline maturity and clinical activity. Current drug highlighted in teal.

Timeline

Expected Milestones

Q1 2027

Phase 1/2Recruiting

Chronic Obstructive Pulmonary Disease

NCT04427826

Clinical

Trials by Indication[1]

Phase II Clinical Trial2 trials

Phase II Clinical Trial to Evaluate the Efficacy and Safety of LPM3480392 Injection for Moderate to Severe Pain After Orthopedic Surgery

Recruiting· Luye Pharma Group Ltd. logo

Luye Pharma Group Ltd.·Phase 2·NCT06467409·150 enrolled

Phase II Clinical Trial to Evaluate the Efficacy and Safety of LPM3480392 Injection for Moderate to Severe Pain After Abdominal Surgery

Completed· Luye Pharma Group Ltd. logo

Luye Pharma Group Ltd.·Phase 2·NCT06204120·150 enrolled

Thoracic Surgery1 trial

Comparison of Tramadol, Pethidine and Morphine in the Treatment of Pain After Thoracic Surgery

Unknown status·—·Phase 4·NCT06172920·45 enrolled

Pain Management1 trial

A Comparison of Three Regimens of Acute Pain Management: Methoxyflurane; Intranasal Fentanyl; Intravenous Morphine

Completed·OOslo University Hospital·Phase 3·NCT05137184·338 enrolled

Idiopathic Scoliosis1 trial

Comparison of the Efficacy of Ketamine in Pediatric Patients With Idiopathic Scoliosis After Surgery

Completed·FFundació Sant Joan de Déu·Phase 2·NCT02571491·48 enrolled

Cesarean Section1 trial

Compared With Different Method for Postcesarean Section Analgesia

Completed·—·N/A·NCT05405049·46 enrolled

5 more indications

Chronic Obstructive Pulmonary Disease1 trial

Efficacy of Morphine in Reducing the Rate of Early Non-Invasive Ventilation Failure in Acute Exacerbation of Chronic Obstructive Pulmonary Disease, Phase I/IIa

Recruiting·UUniversity Hospital, Grenoble·Phase 1/2·NCT04427826·24 enrolled

Pulmonary Fibrosis1 trial

Morphine for Dyspnea in Pulmonary Fibrosis

Unknown status·MMedical University of Gdansk·Phase 3·NCT04497831·20 enrolled

Interstitial Lung Disease1 trial

Palliation of Dyspnea With Morphine in Patients With Interstitial Lung Disease

Completed·UUniversity of Aarhus·Phase 4·NCT02622022·36 enrolled

Perioperative Analgesia1 trial

Hydromorphone for Perioperative Analgesia in Lung Tumor Ablation Parallel Controlled

Unknown status·QQianfoshan Hospital·Phase 4·NCT05848635·88 enrolled

Postoperative Analgesia1 trial

A Randomized, Double-blind, Placebo-controlled, Parallel-group, Multicenter, Phase III Clinical Study to Evaluate the Efficacy and Safety of Nalbuphine Versus Morphine for the Treatment of Postoperative Analgesia

Completed·YYangtze River Pharmaceutical Group Jiangsu Zilong Pharmaceutical Co. Ltd·Phase 3·NCT06949852·289 enrolled

Sources

References

[1]
ClinicalTrials.gov — 11 trial records for Morphine hydrochloride. U.S. National Library of Medicine, National Institutes of Health.
[2]
ChEMBL — Morphine hydrochloride compound record. European Bioinformatics Institute (EMBL-EBI).
[3]
Open Targets Platform — Drug–disease associations for Morphine hydrochloride. EMBL-EBI & Wellcome Sanger Institute.
[4]
SEC EDGAR — Luye Pharma Group Ltd. company filings. U.S. Securities and Exchange Commission.

Details

Drug Info

Quick Facts

Modality: Small molecule[2]
Highest Phase: Approved[1]
Company: Luye Pharma Group Ltd.

Morphine hydrochloride

Status by Indication[3][1]

Competitive Landscape

Expected Milestones

Q1 2027

Trials by Indication[1]

Phase II Clinical Trial2 trials

Thoracic Surgery1 trial

Pain Management1 trial

Idiopathic Scoliosis1 trial

Cesarean Section1 trial

Chronic Obstructive Pulmonary Disease1 trial

Pulmonary Fibrosis1 trial

Interstitial Lung Disease1 trial

Perioperative Analgesia1 trial

Postoperative Analgesia1 trial

References

Drug Info

Quick Facts

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