Morphine hydrochloride

Phase 2Small molecule

Luye Pharma Group Ltd.

Morphine hydrochloride is one of 92 small molecule programs targeting Cesarean Section. It is currently in Phase 2.

Indications

Total Trials

Active Trials

Competitors

Pipeline

Status by Indication[3][1]

Indication

Cesarean SectionActive, not recruiting

Chronic Obstructive Pulmonary DiseaseRecruiting

Cesarean SectionPreclinical

Active, not recruiting

Chronic Obstructive Pulmonary DiseasePhase 2

Recruiting

Competition

Competitive Landscape

120 competitors in Chronic Obstructive Pulmonary Disease

#DrugCompanyPhaseTrials

EXDENSUR

GGlaxo Dba Glaxosmithkline

Phase 3

2 2

Lunsekimig

Sanofi

Phase 3

3 3

Tozorakimab

AstraZeneca

Phase 3

2 4

CM310

KKeymed Biosciences Co.Ltd

Phase 3

1 5

Sildenafil ODT

PPfizer's Upjohn has merged with Mylan to form Viatris Inc.

Phase 2

2 6

Astegolimab

Roche

Phase 3

3 7

Titrated Oxygen

RRigshospitalet, Denmark

Phase 3

1 8

Calciferol

Duragesic

2 10

Morphine hydrochloride

Luye Pharma Group Ltd.

Phase 2

Ranked by pipeline maturity and clinical activity. Current drug highlighted in teal.

Timeline

Expected Milestones

Q1 2027

Phase 1/2Recruiting

Chronic Obstructive Pulmonary Disease

NCT04427826

Clinical

Trials by Indication[1]

Phase II Clinical Trial2 trials

Phase II Clinical Trial to Evaluate the Efficacy and Safety of LPM3480392 Injection for Moderate to Severe Pain After Orthopedic Surgery

Recruiting· Luye Pharma Group Ltd. logo

Luye Pharma Group Ltd.·Phase 2·NCT06467409·150 enrolled

Phase II Clinical Trial to Evaluate the Efficacy and Safety of LPM3480392 Injection for Moderate to Severe Pain After Abdominal Surgery

Completed· Luye Pharma Group Ltd. logo

Luye Pharma Group Ltd.·Phase 2·NCT06204120·150 enrolled

Idiopathic Scoliosis1 trial

Comparison of the Efficacy of Ketamine in Pediatric Patients With Idiopathic Scoliosis After Surgery

Completed·FFundació Sant Joan de Déu·Phase 2·NCT02571491·48 enrolled

Perioperative Analgesia1 trial

Hydromorphone for Perioperative Analgesia in Lung Tumor Ablation Parallel Controlled

Unknown status·QQianfoshan Hospital·Phase 4·NCT05848635·88 enrolled

Chronic Obstructive Pulmonary Disease1 trial

Efficacy of Morphine in Reducing the Rate of Early Non-Invasive Ventilation Failure in Acute Exacerbation of Chronic Obstructive Pulmonary Disease, Phase I/IIa

Recruiting·UUniversity Hospital, Grenoble·Phase 1/2·NCT04427826·24 enrolled

Thoracic Surgery1 trial

Comparison of Tramadol, Pethidine and Morphine in the Treatment of Pain After Thoracic Surgery

Unknown status·—·Phase 4·NCT06172920·45 enrolled

5 more indications

Interstitial Lung Disease1 trial

Palliation of Dyspnea With Morphine in Patients With Interstitial Lung Disease

Completed·UUniversity of Aarhus·Phase 4·NCT02622022·36 enrolled

Pain Management1 trial

A Comparison of Three Regimens of Acute Pain Management: Methoxyflurane; Intranasal Fentanyl; Intravenous Morphine

Completed·OOslo University Hospital·Phase 3·NCT05137184·338 enrolled

Cesarean Section1 trial

Compared With Different Method for Postcesarean Section Analgesia

Completed·—·N/A·NCT05405049·46 enrolled

Pulmonary Fibrosis1 trial

Morphine for Dyspnea in Pulmonary Fibrosis

Unknown status·MMedical University of Gdansk·Phase 3·NCT04497831·20 enrolled

Postoperative Analgesia1 trial

A Randomized, Double-blind, Placebo-controlled, Parallel-group, Multicenter, Phase III Clinical Study to Evaluate the Efficacy and Safety of Nalbuphine Versus Morphine for the Treatment of Postoperative Analgesia

Completed·YYangtze River Pharmaceutical Group Jiangsu Zilong Pharmaceutical Co. Ltd·Phase 3·NCT06949852·289 enrolled

Sources

References

[1]
ClinicalTrials.gov — 11 trial records for Morphine hydrochloride. U.S. National Library of Medicine, National Institutes of Health.
[2]
ChEMBL — Morphine hydrochloride compound record. European Bioinformatics Institute (EMBL-EBI).
[3]
Open Targets Platform — Drug–disease associations for Morphine hydrochloride. EMBL-EBI & Wellcome Sanger Institute.
[4]
SEC EDGAR — Luye Pharma Group Ltd. company filings. U.S. Securities and Exchange Commission.

Details

Drug Info

Quick Facts

Modality: Small molecule[2]
Highest Phase: Phase 2[1]
Company: Luye Pharma Group Ltd.

Morphine hydrochloride

Status by Indication[3][1]

Competitive Landscape

Expected Milestones

Q1 2027

Trials by Indication[1]

Phase II Clinical Trial2 trials

Idiopathic Scoliosis1 trial

Perioperative Analgesia1 trial

Chronic Obstructive Pulmonary Disease1 trial

Thoracic Surgery1 trial

Interstitial Lung Disease1 trial

Pain Management1 trial

Cesarean Section1 trial

Pulmonary Fibrosis1 trial

Postoperative Analgesia1 trial

References

Drug Info

Quick Facts

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