VivoSeq
Other

Cesarean Section

165

Pipeline Programs↗

40

Active Trials↗

45

Companies Involved↗

Cesarean Section is a highly competitive landscape with 165 programs across 45 companies. The most active players are Edison Pharmaceuticals Inc, Javelin Pharmaceuticals, Milestone Pharmaceuticals Inc.. 62 therapies are approved with 22 more in late-stage development.

Intelligence

Pipeline Metrics

Competitive Density

78/100

Pipeline Velocity

43/100

Mech. Concentration

12/100

Completion Rate

89/100

Attrition Rate

8/100

Competition

Competitive Landscape

Bubble size = clinical trials

Approved
Phase 3
Phase 2
Phase 1
Preclinical

Key Players

Top Companies Companies ranked by the number of pipeline programs they run for this disease.

E

Edison Pharmaceuticals Inc

1 program

Phase 1J

Javelin Pharmaceuticals

1 program

Phase 2M

Milestone Pharmaceuticals Inc.

1 program

Phase 2N

Neurim Pharmaceuticals Ltd.

1 program

Phase 2D

Dexcel Pharma Technologies Ltd.

1 program

Phase 2S

Sinew Pharma Inc.

1 program

Phase 2

Pipeline

Programs by Phase

Preclinical64

Meperidine

Quagen

Oxytocin

Retrophin

Bupivacaine

Innocoll

Ropivacaine

Fresenius Kabi Oncology Ltd.

Phenylephrine

Exela Pharma Sciences, LLC.

Phase 14

Ketamine

Aultman Health Foundation

Methylergonovine

Edison Pharmaceuticals Inc

Microbiome Restoration - FMT

Professor Klaus Bønnelykke

Intrathecal Hydromorphone

Mayo Clinic

Phase 213

Ketorolac

Javelin Pharmaceuticals

Melatonin

Neurim Pharmaceuticals Ltd.

Lidocaine IV

Kasr El Aini Hospital

Ceftriaxone

Conrado Roberto Hoffmann Filho

Alpha Lipoic Acid

National Center for Complementary and Integrative Health (NCCIH)

Phase 322

Dexmedetomidine

McNeil Consumer & Specialty Pharmaceuticals, a Division of McNeil-PPC, Inc.

Dexamethasone

Aspen Global Incorporated

Epinephrine

Samson Clinical Operations Pty Ltd

Magnesium Sulfate

Fresenius Kabi Oncology Ltd.

Betamethasone

Schering-Plough

Approved62

Misoprostol

Pfizer

Sevoflurane

AbbVie

Acetaminophen

Kenvue Brands

Rocuronium

Fresenius Kabi Oncology Ltd.

Morphine Sulfate

Merck & Co.

Analysis

Modality Breakdown

100%

Small molecule

222 of 223 classified programs — the dominant modality here.

0%ALL OTHERSProtein / enzyme1<1%

Small molecule leads; the ring shows all 223 classified programs, each share of the total. Modality classified for 100% of 231 pipeline programs.

Analysis

Trial Status

304

clinical trials

Completed179 · 59%
Unknown status61 · 20%
Recruiting21 · 7%
Not yet recruiting16 · 5%
Terminated16 · 5%
Withdrawn7 · 2%
Other4 · 1%

Clinical Trials

Trial Activity

304 trials

Effect of Probiotics Before Cesarean Section on Postoperative Recovery in Pregnant Women
Recruiting·TThird Affiliated Hospital, Sun Yat-Sen University·N/A·NCT06347770·80 enrolled
Effect of Adding a Low-Dose Epinephrine Bolus Prior to Infusion on Maternal Hemodynamic Stability During Cesarean Section
Recruiting·—·Phase 3·NCT07480889·100 enrolled
Management of Postspinal Anesthesia Hypotension During Elective Cesarean Section: Baby Norepinephrine Versus Ephedrine
Recruiting·HHopital Charles Nicolle·N/A·NCT06498076·126 enrolled
Ondansetron Use for Preventing Pruritus in Patients Undergoing Cesarean Section
Recruiting·WWayne State University·Phase 1·NCT06297499·66 enrolled
Virtual Reality Versus Intravenous Dexmedetomidine on Maternal Anxiety, Stress, Hemodynamics, and Neonatal Outcomes During Cesarean Section
Recruiting·—·N/A·NCT07343843·52 enrolled
Oxytocin Bolus Versus Infusion in Elective Cesarean Section"
Recruiting·SStony Brook University·Phase 4·NCT05236985·120 enrolled
Dexmedetomidine Wound Infiltration in Cesarean Section
Recruiting·—·N/A·NCT03382938·100 enrolled
Chloroprocaine 1% Versus Ropivacaine 0,75% During Cesarean Section
Recruiting·—·N/A·NCT06376058·60 enrolled
Comparison of the Therapeutic Effects of VR and VR + Metformin in the Treatment of Cesarean Section Scar Defect
Recruiting·XXinhua Hospital, Shanghai Jiao Tong University School of Medicine·N/A·NCT05205317·100 enrolled
Continuous Infusion of Norepinephrine vs Phenylephrine During Spinal Anesthesia for Cesarean Section (INPEACE)
Recruiting·HHassan II University·Phase 4·NCT06248593·140 enrolled
Efficacy of Acetaminophen Alone Versus Combination of Acetaminophen/Ibuprofen After Cesarean Section
Recruiting·SSeoul National University Hospital·Phase 4·NCT06479122·84 enrolled
Preoperative Clindamycin Vaginal Cream Versus Vaginal Cleansing With Povidone-iodine on Postoperative Infections After Cesarean Section
Recruiting·—·Phase 4·NCT07474194·150 enrolled
COMPARISON BETWEEN EFFICACY OF NOREPINEPHRINE AND PHENYLEPHRINE BOLUSES for PREVENTION OF SPINAL ANAESTHESIA INDUCED HYPOTENSION IN OBSTETRICAL PATIENTS UNDERGOING EMERGENCY CESAREAN SECTION-A Double Blind Randomized Controlled Trial
Recruiting·—·N/A·NCT06836986·124 enrolled
Comparison of Pruritus Incidence After Intrathecal Morphine 0.1 vs 0.2 mg in Cesarean Section
Recruiting·KKhon Kaen University·Phase 4·NCT07054775·69 enrolled
Transversalis Fascia Plane Block Versus Intrathecal Dexmedetomidine in Patients Undergoing Cesarean Section
Recruiting·TTanta University·N/A·NCT07170267·50 enrolled
Page 1 of 21

Data sources: ClinicalTrials.gov (NIH) · OpenFDA (FDA) · ChEMBL (EMBL-EBI) · Open Targets (EBI/Sanger) · MedlinePlus (NIH) · PubMed (NIH) · SEC EDGAR (SEC)