Niclocide
(Niclosamide)ApprovedSmall molecule
BayerNiclosamide is used to treat infections caused by tapeworms and other parasitic worms that live in the intestines. It works by killing the worms so they can be eliminated from the body.[2] Niclocide is currently approved and in use across 7 indications[4].[1]
Niclocide is one of 169 small molecule programs targeting Helminthiasis. It is currently in Approved.
7
Indications
23
Total Trials
2
Active Trials
168
Competitors
1
FDA Application
NDA/BLA/ANDA regulatory filings
Pipeline
Status by Indication[4][1]
Indication
Competition
Competitive Landscape
332 competitors in Treatment
#DrugCompanyPhaseTrials
1Niclocide
BayerApproved
Biltricide
BayerPreclinical
Dexilant
TakedaPreclinical
Alfenta
Jazz PharmaceuticalsPreclinical
Minipress
PfizerPreclinical
Theo-Dur
PfizerPreclinical
Valium
Akero TherapeuticsPreclinical
Lotemax
PPharmos
Preclinical
Norpramin
VValidus Pharmaceuticals
Preclinical
Barhemsys
Tibotec Pharmaceuticals, IrelandPreclinical
Ranked by pipeline maturity and clinical activity. Current drug highlighted in teal.
Timeline
Expected Milestones
Clinical
Trials by Indication[1]
COVID-199 trials
PROphylaxis for paTiEnts at Risk of COVID-19 infecTion -V
Completed·—·Phase 2/3·NCT04870333·2,240 enrolled
Show 6 more trials
Prostate Cancer2 trials
Treatment1 trial
Mass Treatment T Solium Community Study
Terminated·NNational Institute of Allergy and Infectious Diseases (NIAID)·N/A·NCT00138359·4,200 enrolled
9 more indications
Colorectal Cancer1 trial
Drug Trial to Investigate the Safety and Efficacy of Niclosamide Tablets in Patients With Metastases of a Colorectal Cancer Progressing After Therapy
Unknown status·—·Phase 2·NCT02519582·37 enrolled
Proctosigmoiditis1 trial
Metastatic Prostate Cancer1 trial
Regulatory
FDA Approval Timeline[5]
May 14, 1982
NICLOCIDE
NDA NDA018669
Sources
References
- [1]
- [2]MedlinePlus Drug Information — Niclocide drug information. U.S. National Library of Medicine, National Institutes of Health.
- [3]
- [4]Open Targets Platform — Drug–disease associations for Niclosamide. EMBL-EBI & Wellcome Sanger Institute.
- [5]
- [6]