Niclocide
(Niclosamide)ApprovedSmall molecule
BayerNiclosamide is used to treat infections caused by tapeworms and other parasitic worms that live in the intestines. It works by killing the worms so they can be eliminated from the body.[2] Niclocide is currently approved and in use across 7 indications[4].[1]
Niclocide is one of 173 small molecule programs targeting Helminthiasis. It is currently in Approved.
7
Indications
23
Total Trials
2
Active Trials
172
Competitors
1
FDA Application
NDA/BLA/ANDA regulatory filings
Pipeline
Status by Indication[4][1]
Indication
Competition
Competitive Landscape
350 competitors in Treatment
#DrugCompanyPhaseTrials
1Niclocide
BayerApproved
Biltricide
BayerPreclinical
Minipress
PfizerPreclinical
Theo-Dur
PfizerPreclinical
Levulan
Sun Pharmaceutical Industries, Inc.Preclinical
Lamprene
NovartisPreclinical
Emtriva
GileadPreclinical
Hivid
CConrado Roberto Hoffmann Filho
Preclinical
Foscavir
CClinigen, Inc.
Preclinical
Intuniv
PPromius Pharma, LLC
Preclinical
Ranked by pipeline maturity and clinical activity. Current drug highlighted in teal.
Timeline
Expected Milestones
Clinical
Trials by Indication[1]
COVID-199 trials
Show 6 more trials
PROphylaxis for paTiEnts at Risk of COVID-19 infecTion -V
Completed·—·Phase 2/3·NCT04870333·2,240 enrolled
Prostate Cancer2 trials
Metastatic Prostate Cancer1 trial
9 more indications
Colorectal Cancer1 trial
Drug Trial to Investigate the Safety and Efficacy of Niclosamide Tablets in Patients With Metastases of a Colorectal Cancer Progressing After Therapy
Unknown status·—·Phase 2·NCT02519582·37 enrolled
Proctosigmoiditis1 trial
Treatment1 trial
Mass Treatment T Solium Community Study
Terminated·NNational Institute of Allergy and Infectious Diseases (NIAID)·N/A·NCT00138359·4,200 enrolled
Regulatory
FDA Approval Timeline[5]
May 14, 1982
NICLOCIDE
NDA NDA018669
Sources
References
- [1]
- [2]MedlinePlus Drug Information — Niclocide drug information. U.S. National Library of Medicine, National Institutes of Health.
- [3]
- [4]Open Targets Platform — Drug–disease associations for Niclosamide. EMBL-EBI & Wellcome Sanger Institute.
- [5]
- [6]