Padsevonil

Pipeline

Status by Indication[3][1]

Competition

Competitive Landscape

EpilepsyFocal-Onset Seizure

221 competitors in Epilepsy

#DrugCompanyPhaseTrials

1

Briviact

UCB

Phase 3

142

Epidiolex

Jazz Pharmaceuticals

Phase 3

93

Dayvigo

Eisai

Phase 3

14

Depacon

AbbVie

Phase 3

15

Zonegran

AAzurity Pharmaceuticals

Phase 3

56

Actemra

Roche

Phase 3

—7

Deltavit

HHyundai Pharmaceutical Co., LTD.

Phase 3

38

Narcan

SScienture

Phase 3

19

Lamictal

GSK

Phase 3

210

Usual Treatment

UUniversity Hospital, Grenoble

Phase 3

1Show 25 more competitors

Ranked by pipeline maturity and clinical activity. Current drug highlighted in teal.

Clinical

Trials by Indication[1]

Focal-onset seizure3 trials

A Study to Test the Efficacy and Safety of Padsevonil as Treatment of Focal-onset Seizures in Adult Subjects With Drug-resistant Epilepsy

Terminated·UCB·Phase 3·NCT03739840·232 enrolled

Study to Test the Efficacy and Safety of Padsevonil as Adjunctive Treatment of Focal-onset Seizures in Adults With Drug-resistant Epilepsy

Completed·UCB·Phase 2·NCT03373383·411 enrolled

Study to Test the Safety and Efficacy of Padsevonil as Adjunctive Treatment of Focal-onset Seizures in Adult Subjects With Drug-resistant Epilepsy

Terminated·UCB·Phase 2·NCT03370120·406 enrolled

ART2 trials

A Study to Test the Safety, and Tolerability of Padsevonil in Healthy Male Japanese Study Participants

Completed·UCB·Phase 1·NCT04075409·39 enrolled

A Study to Test the Pharmacodynamic, Pharmacokinetic, Safety, and Tolerability of Padsevonil in Healthy Study Participants Receiving Either Ethanol or Cannabidiol

Terminated·UCB·Phase 1·NCT04039919·40 enrolled

Epilepsy1 trial

A Study in Participants With Epilepsy, to Evaluate the Pharmacokinetics, Safety and Tolerability of Oxcarbazepine on Padsevonil

Completed·UCB·Phase 1·NCT03695094·31 enrolled

Elderly1 trial

A Study to Test the Safety and Tolerability of Single and Multiple Doses of Padsevonil in Adult and Elderly Study Participants

Completed·UCB·Phase 1·NCT04013191·28 enrolled

Cardiac1 trial

A Study to Test the Cardiac Effects of Padsevonil in Healthy Study Participants

Terminated·UCB·Phase 1·NCT04126343·54 enrolled

4 more indications

Tics1 trial

Study to Evaluate the Effect of Coadministered Erythromycin on the Pharmacokinetics and Safety of Padsevonil

Completed·UCB·Phase 1·NCT03480243·28 enrolled

Interaction1 trial

A Study to Test the Interaction of Padsevonil With Oral Contraceptives in Healthy Female Participants

Terminated·UCB·Phase 1·NCT04131517·14 enrolled

Concentration1 trial

A Study to Test the Blood Concentration of 4 Padsevonil Product Variants and the Effect of Food on Padsevonil

Withdrawn·UCB·Phase 1·NCT04283136

Hepatic Function1 trial

A Pharmacokinetic Study of Padsevonil in Study Participants With Either Normal or Moderately Impaired Hepatic Function

Terminated·UCB·Phase 1·NCT04136444·12 enrolled

Details

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