Deltavit

(Cholecalciferol)

Phase 3Small molecule

Cholecalciferol is vitamin D3, which helps your body absorb calcium to keep bones strong and healthy. It's used to treat vitamin D deficiency and conditions like osteoporosis and low calcium levels.[1] Deltavit is currently being investigated across 15 indications[3], with its most advanced program in Phase 3.[1]

Deltavit is one of 222 small molecule programs targeting Stage 5 Chronic Kidney Disease. It is currently in Phase 3.

Indications

167

Total Trials

Active Trials

221

Competitors

Pipeline

Status by Indication[3][1]

Indication

Stage 5 Chronic Kidney DiseaseActive, not recruiting

UrolithiasisActive, not recruiting

RicketsActive, not recruiting

Iron Deficiency AnemiaUnknown

Mental DeteriorationActive, not recruiting

Anemia (phenotype)Unknown

Bed SoresRecruiting

Postmenopausal OsteoporosisUnknown

HyperbilirubinemiaActive, not recruiting

EnuresisActive, not recruiting

Stage 5 Chronic Kidney DiseasePreclinical

Active, not recruiting

UrolithiasisPreclinical

Active, not recruiting

RicketsPreclinical

Active, not recruiting

Iron Deficiency AnemiaPreclinical

Unknown

Mental DeteriorationPreclinical

Active, not recruiting

Anemia (phenotype)Preclinical

Unknown

Bed SoresPreclinical

Recruiting

Postmenopausal OsteoporosisPreclinical

Unknown

HyperbilirubinemiaPreclinical

Active, not recruiting

EnuresisPreclinical

Active, not recruiting

Showing 10 of 15 indications

Competition

Competitive Landscape

157 competitors in Hypertension

#DrugCompanyPhaseTrials

Baxfendy

AstraZeneca

Phase 3

3 2

Foundayo

Eli Lilly

Phase 3

3 3

Nitrostat

VViatris Specialty LLC

Phase 3

5 4

Deltavit

HHyundai Pharmaceutical Co., LTD.

Phase 3

2 5

Alka-Seltzer

AAbbott

Phase 3

1 6

Minocycline /d

UUniversity of Florida

Phase 3

1 7

Avastin

Roche

Preclinical

1 8

Winrevair

Alphagan

Disalcid

JJoslin Diabetes Center

Preclinical

Ranked by pipeline maturity and clinical activity. Current drug highlighted in teal.

Timeline

Expected Milestones

Q4 2026

Recruiting

Dialysis Patients

NCT06571344

Q1 2027

Phase 3Recruiting

Mortality

NCT03188796

PreclinicalRecruiting

Bed Sores

NCT07813975

Clinical

Trials by Indication[1]

Vitamin D21 trials

Vitamin D AND Glucose Handling Evaluated by Glucose Clamp

Completed·UUniversity Hospital of North Norway·Phase 2·NCT00809744·160 enrolled

Vitamin D Levels in the Skin of Healthy Subjects After Oral Supplementation

Completed·NNational Cancer Institute (NCI)·Phase 1·NCT01447355·25 enrolled

Effects Vitamin D Suppletion on Postprandial Leukocyte Activation

Completed·SSint Franciscus Gasthuis·N/A·NCT01967459·24 enrolled

Show 18 more trials

The GLOBAL Vitamin D Study. A Genomic, Transcriptomic, Proteomic and Metabolomic Approach

Completed·UUniversity of Tromso·Phase 2·NCT02783924·50 enrolled

Effects Of Vitamin D On Bone, Muscle, And Adipose Tissue In Obese Subjects

Recruiting·FFondazione Policlinico Universitario Campus Bio-Medico·Phase 4·NCT06508242·80 enrolled

The Effect of Inactive and Active Vitamin D on Serum Sclerostin/dickkopf1 Levels

Unknown status·SSeoul National University Hospital·Phase 4·NCT01765010·88 enrolled

Vitamin D and Muscle Strength and Surface (Electromyography) EMG

Completed·IIndian Council of Medical Research·Phase 3·NCT01190683·170 enrolled

The Significance of Vitamin D Storage in Adipose Tissue

Withdrawn·UUniversity of Tromso·Phase 2·NCT01728987

Vitamin D Supplementation in RNA-seq Profiles of Single-core Prostate Samples, Among Veterans

Completed·MMedical University of South Carolina·Phase 2·NCT04621500·60 enrolled

Vitamin D and Walking Ability in Patients With Peripheral Artery Occlusive Disease

Terminated·UUniversity Hospital, Basel, Switzerland·Phase 4·NCT01559974·4 enrolled

The Effect of Vitamin D Supplementation on HIV-associated Platelet Hyperreactivity

Completed·UUniversitas Padjadjaran·N/A·NCT02217553·50 enrolled

Ultra-high Dose Vitamin D for HSCT

Completed·—·Phase 1·NCT03759262·33 enrolled

Vitamin D Supplementation and Regulatory FoxP3+ T Cells in the GUT

Completed·MMedical University of Graz·Phase 4·NCT01538485·16 enrolled

Changes in Serum Vitamin D Level After Different Loading Doses of Cholecalciferol

Completed·—·N/A·NCT03504280·105 enrolled

'Palliative-D' Vitamin D to Palliative Cancer Patients

Completed·RRegion Stockholm·Phase 2·NCT03038516·244 enrolled

Immune and Metabolic Effects of Vitamin D Supplementation in Healthy Humans

Completed·MMedical University of Graz·Phase 4·NCT01248442·60 enrolled

Vitamin D Dose Finding Study

Completed·—·Phase 2·NCT01092338·44 enrolled

Effect of Vitamin D Oral Supplements on 25 OH Vitamin D Levels

Completed·KKing Faisal Specialist Hospital & Research Center·N/A·NCT01170494·279 enrolled

Vitamin D Supplementation in Women With DCIS and/or LCIS

Terminated·IInova Health Care Services·Phase 1·NCT02936999·8 enrolled

Diabetes Intervention Trial With Vitamin D in Subjects of Nordic and Sub-Indian Ethnicity

Unknown status·UUniversity Hospital, Aker·Phase 2·NCT00992797·60 enrolled

In Inflammatory Bowel Diseases Associated With Vitamin D Deficiency, Can Vitamin D Replacement Correct Chronic Disease Anemia?

Completed·GGazi University·Approved·NCT07673497·43 enrolled

Vitamin D Deficiency9 trials

Rapid Normalization of Vitamin D Deficiency in PICU

Completed·—·Phase 3·NCT03742505·424 enrolled

VITdAL@ICU - Correction of Vitamin D Deficiency in Critically Ill Patients

Completed·—·Phase 3·NCT01130181·480 enrolled

Vitamin D Deficiency and Postoperative Hypocalcemia

Unknown status·UUniversity of Sao Paulo General Hospital·Phase 4·NCT01632514·90 enrolled

Show 6 more trials

Treatment of Vitamin D Deficiency With Large Bolus Cholecalciferol

Terminated·—·Phase 1·NCT04120064·60 enrolled

Characterization of Hyperparathyroidism and Vitamin D Deficiency in Obesity

Completed·WWeill Medical College of Cornell University·Phase 4·NCT00288873·60 enrolled

Controlled Trial of Prenatal Vitamin D3 Supplementation to Prevent Vitamin D Deficiency in Mothers and Their Infants

Completed·—·Phase 3·NCT00610688·192 enrolled

Synergistic Effect of Vitamin D Supplementation in Patients With Vitiligo and Vitamin D Deficiency

Completed·HHallym University Kangnam Sacred Heart Hospital·N/A·NCT05364567·29 enrolled

Vitamin D Deficiency and Asthma Exacerbation

Completed·UUniversity of Turin, Italy·N/A·NCT02661191·119 enrolled

Cholecalciferol Supplementation in Critically Ill Patients With Severe Vitamin D Deficiency.

Terminated·KKing Abdullah Medical City·Phase 2/3·NCT02868827·127 enrolled

Dialysis Patients8 trials

Impact of Vitamin D Repletion in Hemodialysis Patients

Completed·—·N/A·NCT01175798·116 enrolled

Cholecalciferol on Hemodialysis Patients

Completed·—·Phase 2/3·NCT03602430·60 enrolled

Vitamin D in Dialysis Patients - Diagnostic and Therapeutic Management

Recruiting·MMedical University of Gdansk··NCT06571344·160 enrolled

Show 5 more trials

Cholecalciferol Supplementation Effect on Parathyroid Hormone in Hemodialysis Patients

Completed·CCooperativa Asistencia Sindicato Médico Uruguay·Phase 4·NCT03648528·120 enrolled

Supplementation With Cholecalciferol in Dialysis Patients

Completed·FFederal University of São Paulo·Phase 2·NCT01974245·55 enrolled

Cholecalciferol Supplementation in Hemodialysis Patients

Completed·—·Phase 2/3·NCT05922696·50 enrolled

Vitamin D3 Supplementation in Dialysis Patients

Completed·RRegional Hospital Holstebro·Phase 2·NCT01312714·64 enrolled

Effect of 25-hydroxyvitamin D and a Structured Exercise Program on Dialysis Patients

Completed·SSir Charles Gairdner Hospital·Phase 4·NCT00798993·19 enrolled

Breast Cancer5 trials

Changes in Breast Cancer Biomarkers Using Synergistic Prostaglandin Inhibitors

Completed·HHartford Hospital·Phase 1/2·NCT01425476·45 enrolled

Safety, Feasibility and Efficacy of Vitamin D Supplementation in Women With Metastatic Breast Cancer (SAFE-D)

Completed·LLoyola University·Phase 2·NCT02186015·43 enrolled

Randomized Controlled Trial of Neo-adjuvant Progesterone and Vitamin D3 in Women With Large Operable Breast Cancer and Locally Advanced Breast Cancer

Terminated·TTata Memorial Hospital·Phase 3·NCT01608451·800 enrolled

Show 2 more trials

Study of Vitamin D for Premenopausal Women at High Risk for Breast Cancer

Completed·—·Phase 1·NCT00976339·20 enrolled

Vitamin D in Postmenopausal Women at High Risk for Breast Cancer

Completed·—·Phase 2·NCT00859651·20 enrolled

COVID-195 trials

Effect of Vitamin D on Hospitalized Adults With COVID-19 Infection

Completed·UUniversity of Liege·Phase 4·NCT04636086·50 enrolled

Ivermectin-Azithromycin-Cholecalciferol (IvAzCol) Combination Therapy for COVID-19

Completed·IInstituto de Seguridad y Servicios Sociales de los Trabajadores del Estado·N/A·NCT04399746·30 enrolled

Efficacy of Vitamin D Supplementation to Prevent the Risk of Acquiring COVID-19 in Healthcare Workers

Completed·CCoordinación de Investigación en Salud, Mexico·Phase 3·NCT04535791·321 enrolled

Show 2 more trials

The Effect of Novel D3 Use as a Mouthwash in COVID-19 Patients

Completed·KKing Faisal Specialist Hospital & Research Center·Phase 1·NCT07068282·25 enrolled

Efficacy of Vitamin D Treatment in Pediatric Patients Hospitalized by COVID-19

Completed·CCoordinación de Investigación en Salud, Mexico·Phase 3·NCT04502667·45 enrolled

76 more indications

Vitamin D35 trials

Vitamin D3 and the Stress-axis in MS

Terminated·—·Phase 2·NCT02096133·54 enrolled

Vitamin D3 in Sensory Recovery After Digital NERVe Suture (D3NERV).

Unknown status·UUniversity Hospital, Caen·Phase 3·NCT04115982·72 enrolled

The Efficacy and the Safety of Vitamin D3 30,000 IU for Loading Dose Schedules

Completed·SSemmelweis University·Phase 3·NCT04476511·75 enrolled

Show 2 more trials

Effect of Vitamin D3 on Lung Function and Exercise Tolerance in COPD Patients

Completed·—·Phase 1·NCT03781895·48 enrolled

The Pharmacokinetics of a Single Large Dose of Vitamin D3

Completed·—·N/A·NCT00473239·40 enrolled

Chronic Kidney Disease5 trials

Vitamin D as a Modifier of Serum Hepcidin in Children With Chronic Kidney Disease

Completed·JJohns Hopkins University·Phase 2·NCT01532349·34 enrolled

Cholecalciferol (Vitamin D3) Therapy in Chronic Kidney Disease (CKD) Subjects

Completed·—·N/A·NCT00427037·34 enrolled

Vitamin D Supplement Study for Stage Three and Four Chronic Kidney Disease (CKD) Patients

Terminated·TThe Cleveland Clinic·Phase 3·NCT01173848·19 enrolled

Show 2 more trials

Vitamin D and Arterial Function in Patients With Chronic Kidney Disease

Completed·UUniversity of Colorado, Denver·Phase 3·NCT01384539·128 enrolled

Study of Vitamin D3 Supplementation in Patients With Chronic Kidney Disease

Completed·SSahlgrenska University Hospital·N/A·NCT00893451·24 enrolled

Type 2 Diabetes4 trials

Metabolic Effects of Vitamin D in Patients With Type 2 Diabetes

Completed·UUniversity of Aarhus·Phase 2·NCT00812578·16 enrolled

Vitamin D for Established Type 2 Diabetes (DDM2)

Completed·TTufts Medical Center·Phase 2/3·NCT01736865·127 enrolled

Can Vitamin D3 Improve Cognitive Function in Individuals With Type 2 Diabetes? (THINK-D)

Terminated·LLoyola University·Phase 2·NCT02416193·56 enrolled

Show 1 more trial

Vitamin D Supplementation to Patients With Type 2 Diabetes

Completed·UUniversity of Tromso·Phase 2·NCT00400491·40 enrolled

Obesity4 trials

The Link Between Obesity And Vitamin D in Bariatric Patients With Omega-loop Bypass Surgery

Completed·MMaria Luger·Phase 4·NCT02092376·50 enrolled

Effects of Vitamin D Supplementation in Obesity

Completed·UUniversity of Aarhus·Phase 4·NCT01037140·55 enrolled

Study to Evaluate the Pharmacokinetics of Vitamin D (Cholecalciferol) in Patients Undergoing Obesity Surgery in a Deficit Situation and After Standardization

Unknown status·HHospital Clinic of Barcelona·Phase 2·NCT01637155·44 enrolled

Show 1 more trial

Treatment of Obesity With Vitamin D (40.000 IE Per Week for 1 Year)

Completed·UUniversity of Tromso·Phase 2·NCT00243256·450 enrolled

Heart Failure3 trials

Pilot Study of Vitamin D Supplementation in Heart Failure

Completed·FFraser Health·N/A·NCT01388855·13 enrolled

Vitamin D Supplementation in Chronic Stable Heart Failure

Completed·MMedical University of Graz·Phase 3·NCT01292720·29 enrolled

Effects of Cholecalciferol Supplementation in Patients With Chronic Heart Failure and LOw vITamind D Levels

Unknown status·AAzienda Unita' Sanitaria Locale Di Modena·Phase 2/3·NCT01477801·34 enrolled

Secondary Hyperparathyroidism3 trials

Repeated-dose Safety, Efficacy, Pharmacokinetic and Pharmacodynamic of CTAP101, Immediate-release Calcifediol, High-dose Cholecalciferol, and Paricalcitol Plus Low-dose Cholecalciferol in Patients With Secondary Hyperparathyroidism, Chronic Kidney Disease 3-4 and Vitamin D Insufficiency

Completed·OOPKO Health, Inc.·Phase 4·NCT03588884·69 enrolled

Trial Of Paricalcitol and Cholecalciferol(Vitamin D3) in the Treatment Of Secondary Hyperparathyroidism in Patients After ROUX-EN-Y Gastric Bypass Surgery

Completed·—·Phase 3·NCT01138475·49 enrolled

Cholecalciferol Versus Doxercalciferol in the Treatment of Secondary Hyperparathyroidism in Chronic Kidney Disease

Completed·IIndiana University School of Medicine·N/A·NCT00285467·55 enrolled

Systemic Lupus Erythematosus3 trials

Vitamin D Therapy in Patients With Systemic Lupus Erythematosus (SLE)

Completed·MMedical University of South Carolina·Phase 1·NCT00418587·18 enrolled

Vitamin D Supplementation in Systemic Lupus Erythematosus

Completed·AAssistance Publique - Hôpitaux de Paris··NCT01413230·20 enrolled

Cholecalciferol Supplementation on Disease Activity, Fatigue and Bone Mass on Juvenile Systemic Lupus Erythematosus.

Completed·RROSA MARIA RODRIGUES PEREIRA·N/A·NCT01892748·60 enrolled

Epilepsy3 trials

Effect of Three Different Doses of Oral Cholecalciferol on 25-Hydroxyvitamin D Changes Among Epilepsy Patients With Hypovitaminosis D

Completed·—·Phase 4·NCT02890823·210 enrolled

Vitamine D in Drug Resistant Epilepsy

Completed·—·Phase 3·NCT03475225·88 enrolled

The Role of Vitamin D in Neuroinflammatory on Drug Resistant Epilepsy

Unknown status·DDINA KEUMALA SARI·Phase 1·NCT06053281·70 enrolled

Postmenopausal Osteoporosis2 trials

Frequency of Hyperparathyroidism in Postmenopausal Osteoporosis and Its Treatment

Completed·HHospital Regional 1o de Octubre·N/A·NCT05347082·47 enrolled

Effect of Vitamin D and Denosumab on Bone Remodelling in Women With Postmenopausal Osteoporosis

Completed·HHospital Regional 1o de Octubre·N/A·NCT05372224·55 enrolled

Chronic Obstructive Pulmonary Disease2 trials

This Study Include Asthma Chronic Obstructive Pulmonary Disease (COPD) Overlap Patients.Patients Were Vitamin D Deficient.Age Range 40-70 Years, Smokers.Patients Were Advised to Take Either Placebo or Vitamin D3.Lung Functions and Exercise Tolerance Were Assessed at Baseline and at 26th Weeks.

Completed·—·Phase 2·NCT03880734·70 enrolled

This Study Include Chronic Obstructive Pulmonary Disease(COPD) Patients . Patients Were Vitamin D Deficient Age Range 40 to 80 Years, Smokers Patients Were Advised to Take Either Placebo or Vitamin D3 . Antioxidant Enzymes Were Assessed at Baseline and at 26th Weeks.

Unknown status·—·Phase 2·NCT04011930·40 enrolled

Non-Alcoholic Fatty Liver Disease2 trials

Effectiveness of Inactive Vitamin D Supplementation in Non-Alcoholic Fatty Liver Disease Patients

Unknown status·—·Phase 3·NCT05613192·100 enrolled

High Oral Loading Dose of Cholecalciferol in Non-Alcoholic Fatty Liver Disease

Completed·TTanta University·Phase 2·NCT05578404·100 enrolled

Pregnant Women2 trials

The Effect of Vitamin D3 Therapy on Vitamin D Status in Pregnant Women With Vitamin D Deficient and Insufficient

Unknown status·IIndonesia University·Phase 2/3·NCT06054919·52 enrolled

Vitamin D Status of Pregnant Women and Their Children in Eau Claire, South Carolina

Completed·MMedical University of South Carolina·Phase 3·NCT00412087·564 enrolled

Treatment2 trials

Dosage Calculation for Vitamin D Treatment

Completed·—·Phase 4·NCT02186106·31 enrolled

30000 IU Per Week Vitamin D Treatment in PCOS Patients

Completed·SSemmelweis University·Phase 2·NCT04840238·115 enrolled

Schizophrenia2 trials

Targeted Vitamin D Treatment of Schizophrenia-Associated Hyperprolinemia

Withdrawn·NNYU Langone Health·Phase 2·NCT02197286

Influence of Vitamin D Supplementation on Serum BDNF Level and Cognitive Function in Schizophrenia

Unknown status·UUniversitas Padjadjaran·Phase 3·NCT03284294·40 enrolled

Blood Pressure2 trials

Vitamin D, Blood Pressure, Lipids, Infection and Depression

Completed·UUniversity of Tromso·Phase 3·NCT00960232·250 enrolled

Blood Pressure in Blacks and Calcium (BBC) and Vitamin D Study

Completed·LLoyola University·Phase 2·NCT03070483·5 enrolled

Endothelial Function2 trials

Impact of Vitamin D on Endothelial Function and Blood Biomarkers Including CD28 Null Cells in CKD

Completed·SSt George's, University of London·Phase 3·NCT02005718·36 enrolled

Vitamin D to Improve Endothelial Function in SLE

Completed·MMedical University of South Carolina·Phase 2·NCT01911169·9 enrolled

Cardiovascular Risk Factor2 trials

Vitamin D Supplementation on Cardiovascular Risk Factors

Completed·FFlorida International University·N/A·NCT01412710·92 enrolled

The Effect of Vitamin D Supplementation on Cardiovascular Risk Factors

Completed·UUniversity of Tromso·Phase 3·NCT02750293·411 enrolled

Cystic Fibrosis2 trials

Randomized Study of Alendronate in Adult Patients With Cystic Fibrosis Related Osteoporosis

Completed·UUniversity of North Carolina·N/A·NCT00004489·60 enrolled

Vitamin D as an Adjunctive Treatment in Patients With Non-Cystic Fibrosis Bronchiectasis

Unknown status·SShanghai Pulmonary Hospital, Shanghai, China·Phase 4·NCT02507843·200 enrolled

Osteopenia2 trials

Phase II Randomized Study of Alendronate Sodium for Osteopenia in Patients With Gaucher's Disease

Completed·—·Phase 2·NCT00004488·82 enrolled

Effect of Raloxifene Plus Cholecalciferol and Cholecalciferol Alone on the Bone Mineral Density in Postmenopausal Women With Osteopenia

Completed·YYonsei University·Phase 4·NCT05386784·112 enrolled

Peritonitis2 trials

Oral Vitamin D Supplementation Prevent Peritoneal Dialysis-related Peritonitis

Recruiting·PPeking University First Hospital·Phase 4·NCT05860270·176 enrolled

The Effects of Oral Vitamin D Supplementation on the Prevention of Peritoneal Dialysis-related Peritonitis

Completed·PPeking University First Hospital·Phase 2·NCT03264625·60 enrolled

Efficacy and Safety2 trials

Controlled, Randomized, Four-arm Comparative, Open Label, Multi-centric Clinical Trial to Compare the Efficacy and Safety Parameters of the Once-a-week or Once-a-month Administered 7000 IU, or 30000 IU Vitamin D (Cholecalciferol) to a 1000 IU Dosage Applied Daily in Vitamin D Deficient Patients

Completed·SSemmelweis University·Phase 3·NCT02069990·89 enrolled

Efficacy and Safety of High Dose Vitamin D Supplementation in Patients Undergoing HSCT

Unknown status·SSeoul National University Hospital·Phase 2·NCT03320915·88 enrolled

Mortality2 trials

Effect of Vitamin D on Morbidity and Mortality of the COVID-19

Unknown status·FFundación para la Investigación Biosanitaria del Principado de Asturias·Phase 4·NCT04552951·80 enrolled

The VITDALIZE Study: Effect of High-dose Vitamin D3 on 28-day Mortality in Adult Critically Ill Patients

Recruiting·MMedical University of Graz·Phase 3·NCT03188796·2,400 enrolled

Hypertension2 trials

DAYLIGHT: Vitamin D Therapy in Individuals at High Risk of Hypertension

Completed·MMassachusetts General Hospital·N/A·NCT01240512·534 enrolled

Effect of Vitamin D Replacement During Winter Months in Patients With Hypertension

Completed·RRegional Hospital Holstebro·Phase 2·NCT01166165·136 enrolled

Tuberculosis2 trials

Replacement of Vitamin D in Patients With Active Tuberculosis

Completed·—·N/A·NCT01130311·259 enrolled

Trial of Adjunctive Vitamin D in Tuberculosis Treatment

Completed·BBarts & The London NHS Trust·Phase 3·NCT00419068·146 enrolled

Staphylococcus Aureus2 trials

Efficacy Study of Vitamin D Supplementation to Meticillin Resistant Staphylococcus Aureus (MRSA) Carriers

Completed·PPeter Bergman·Phase 2·NCT02178488·60 enrolled

Vitamin D and Staphylococcus Aureus in the Diabetes Study

Completed·UUniversity of Tromso·Phase 3·NCT01395290·280 enrolled

Prostate Cancer2 trials

Vitamin D and Prostate Cancer: A Clinical Study Enrolling Subjects Undergoing Prostatectomy

Completed·MMedical University of South Carolina·Phase 2·NCT02726113·50 enrolled

Cholecalciferol and Genistein Before Surgery in Treating Patients With Early Stage Prostate Cancer

Completed·NNational Cancer Institute (NCI)·Phase 2·NCT01325311·15 enrolled

Diabetic Neuropathy2 trials

Vitamin D and Painful Diabetic Neuropathy

Unknown status·—·N/A·NCT05080530·216 enrolled

Vitamin D Treatment for Painful Diabetic Neuropathy

Completed·—·N/A·NCT02737423·143 enrolled

Pilot Study2 trials

Mothers' Own Milk Optimization for Preterm Infants Project (MoMO PIP) Pilot Study

Terminated·MMedical University of South Carolina·Phase 4·NCT04629534·8 enrolled

Pilot Study of OMEGA-3 and Vitamin D in High-Dose in Type I Diabetic Patients

Completed·RRodolfo Alejandro·Phase 1/2·NCT03406897·27 enrolled

Hypocalcemia1 trial

Prevention of Postoperative Hypocalcemia of Oral Vitamin D Supplementation Before Total Thyroidectomy

Completed·SSeoul National University Hospital·Phase 4·NCT05216419·108 enrolled

Diabetes, Type 21 trial

Vitamin D for the Prevention of Diabetes Type 2

Completed·UUniversity of Tromso·Phase 2/3·NCT00685594·511 enrolled

Peritoneal Dialysis1 trial

Effects of Cholecalciferol on Osteoprotegerin Levels in Patients on Peritoneal Dialysis

Unknown status·IInstituto Nacional de Ciencias Medicas y Nutricion Salvador Zubiran·Phase 4·NCT02598635·58 enrolled

Primary Hyperparathyroidism1 trial

Effect of Vitamin D Treatment in Primary Hyperparathyroidism

Completed·UUniversity of Aarhus·Phase 2/3·NCT00674154·46 enrolled

Insulin resistance1 trial

Vitamin D, C-reactive Protein and Insulin Resistance

Completed·IInstituto Nacional de Salud Publica, Mexico·Phase 3·NCT01019642·104 enrolled

Immunotherapy1 trial

Vitamin D and Grass Pollen Specific Immunotherapy

Completed·—·Phase 2·NCT01466465·35 enrolled

Peripheral Arterial Disease1 trial

Pilot Study of Vitamin D Screening Use in Peripheral Arterial Disease Patient Over Maximum Distance Walking

Completed·UUniversity Hospital, Angers·Phase 4·NCT03615833·27 enrolled

Interaction1 trial

A Drug-drug Interaction Study of DP-R213

Completed·AAlvogen Korea·Phase 1·NCT02654093·24 enrolled

Elderly1 trial

The Effect of Cholecalciferol in Pre-frail Elderly

Completed·IIndonesia University·Phase 3·NCT04847947·120 enrolled

Inflammation1 trial

The Effect of Supplementation of Vitamin D3 on Inflammation Induced by 100 km Running, Iron Metabolism and Erythropoiesis

Completed·—·N/A·NCT05880030·40 enrolled

SARS-CoV-21 trial

The Effect of Vitamin D Therapy on Morbidity and Moratlity in Patients With SARS-CoV 2 Infection

Completed·KKasr El Aini Hospital·N/A·NCT04733625·56 enrolled

Asthma1 trial

Personalized Treatment Algorithms for Difficult-to-treat Asthma

Completed·—·Phase 2·NCT04179461·21 enrolled

Type 1 Diabetes1 trial

Effects of Vitamin D Supplementation in Subjects With New Onset of Type 1 Diabetes

Completed·MMedical University of Graz·Phase 4·NCT01390480·31 enrolled

Keloid1 trial

Effect of Vitamin D Injection on Hypertrophic Scars and Keloids

Completed·MMostafa Bahaa·Phase 1/2·NCT06301178·35 enrolled

Pregnancy1 trial

Evaluation of Vitamin D Requirements During Pregnancy

Completed·MMedical University of South Carolina·Phase 3·NCT00292591·501 enrolled

Renal insufficiency1 trial

Vitamin D and Chronic Renal Insufficiency

Completed·OOdense University Hospital·Phase 3·NCT00968877·56 enrolled

Trial1 trial

HDDO-1614 Intervention Trial

Completed·HHyundai Pharmaceutical Co., LTD.·Phase 1·NCT03234244·37 enrolled

Wheezing1 trial

Wheezing in Black Preterm Infants: Impact of Vitamin D Supplementation Strategy

Completed·—·Phase 4·NCT01601847·300 enrolled

Cholesterol1 trial

Effect of an Inhibitor of Cholesterol Absorption on Vitamin D Levels

Completed·FFederal University of Rio Grande do Sul·Phase 4·NCT02234544·52 enrolled

Acute Bronchiolitis1 trial

Vitamin D Supplementation for Acute Bronchiolitis

Completed·MMansoura University·Phase 2·NCT03799406·60 enrolled

Neurofibromatosis Type 11 trial

Vitamin D Supplementation for Adults With Neurofibromatosis Type 1 (NF1)

Terminated·UUniversity of Utah·Phase 2·NCT01968590·26 enrolled

Hemodialysis1 trial

Hemodialysis Vitamin D Pilot

Completed·SSt. Joseph's Healthcare Hamilton·N/A·NCT01214928·20 enrolled

Immunomodulation1 trial

Vitamin D Supplementation as Non-toxic Immunomodulation in Children With Crohn's Disease

Terminated·UUniversity of California, Los Angeles·Phase 1·NCT01046773·3 enrolled

Multiple Sclerosis1 trial

Safety and Immunologic Effect of Low Dose Versus High Dose Vitamin D3 in Multiple Sclerosis

Completed·JJohns Hopkins University·Phase 1·NCT01024777·40 enrolled

Oxidative Stress1 trial

Vitamin D, Oxidative Stress and Inflammation in Hemodialysis

Completed·—·Phase 2/3·NCT05460338·25 enrolled

Bone Health1 trial

Effects of Cholecalciferol Supplementation on Bone Health and Muscle Strength in Adults During Post-burn Period

Completed·UUniversity of Liege·N/A·NCT02092701

Insulin Sensitivity1 trial

A Trial to Study the Effect of Long Term Vitamin D Supplementation on Insulin Sensitivity

Completed·DDr Jitender Nagpal·Phase 4·NCT01052181·300 enrolled

Renal Transplant1 trial

Paricalcitol Versus Calcitriol for the Management of Renocardiac Syndrome in Renal Transplant Patients

Completed·UUral State Medical University·Phase 4·NCT01265615·109 enrolled

Periodontal Disease1 trial

Periodontal and Cardiometabolic Responses to Vitamin D Intervention in African Americans With Periodontal Disease

Unknown status·—·Phase 1·NCT02337257·24 enrolled

Atopic Dermatitis1 trial

PRAgmatic Trial in Atopic Dermatitis Testing Long-term Control Effectiveness of New Phototherapy Regimen During Winter Coupled With Oral Vitamin D Supplementation vs. Placebo

Completed·RRennes University Hospital·Phase 2·NCT02537509·111 enrolled

End-Stage Renal Disease1 trial

Role of Extrarenal 1-Alpha-Hydroxylase in Patients With End Stage Renal Disease

Completed·UUniversity of Kansas·N/A·NCT00677534·7 enrolled

CLE1 trial

Cholecalciferol Supplementation, Muscle Strength

Completed·IIndian Council of Medical Research·Phase 1·NCT00682214·40 enrolled

Kidney Transplant1 trial

Vitamin D3 Substitution in Vitamin D Deficient Kidney Transplant Recipients

Unknown status·MMedical University of Vienna·Phase 3·NCT00752401·200 enrolled

Newly Diagnosed1 trial

Deferasirox, Cholecalciferol, and Azacitidine in the Treatment of Newly Diagnosed AML Patients Over 65

Terminated·EElizabeth Henry·Phase 2·NCT02341495·4 enrolled

Hypovitaminosis D1 trial

Hypovitaminosis D in Neurocritical Patients

Completed·UUniversity of Utah·Phase 2/3·NCT02881957·274 enrolled

Hematologic Disease1 trial

The Effect of 25-OH-Vitamin-D3 Substitution in Patients With Malignant and Immune-hematologic Diseases

Terminated·SSemmelweis University·Phase 3·NCT01518959·31 enrolled

Pulmonary Tuberculosis1 trial

Pulmonary Tuberculosis and Vitamin D

Unknown status·IIndian Council of Medical Research·Phase 3·NCT00507000·150 enrolled

Crohn's Disease1 trial

Trial of High Dose Vitamin D in Patient's With Crohn's Disease

Terminated·UUniversity of Michigan·Phase 4·NCT02208310·11 enrolled

Osteoporosis1 trial

High Dosage Vitamin D and Osteoporosis

Completed·UUniversity Hospital of North Norway·Phase 4·NCT00491920·297 enrolled

Adolescent1 trial

Efficacy of Usual Vitamin D Supplementation and Its Impact on Children and Adolescents Calciuria.

Completed·HHospices Civils de Lyon·Phase 4·NCT02238418·43 enrolled

Bronchiectasis1 trial

The Role of Vitamin D3 in Pediatric Bronchiectasis Severity

Completed·HHeba Omara·Phase 2/3·NCT04411901·40 enrolled

Spinal Cord Injury1 trial

Vitamin D Supplementation in Individuals With a Chronic Spinal Cord Injury

Completed·SSwiss Paraplegic Research, Nottwil·Phase 3·NCT04652544·50 enrolled

Calcification1 trial

Effect of Vitamin K 2 on Vascular Calcification in Hemodialysis Patients

Unknown status·—·Phase 2/3·NCT04145492·60 enrolled

Hip Fracture1 trial

Early Rehabilitation After Hip Fracture

Unknown status·SSwiss National Science Foundation·Phase 3·NCT00133640·204 enrolled

Chronic Pancreatitis1 trial

Vitamin D Substitution for Patients With Chronic Pancreatitis and Malabsorption

Completed·HHvidovre University Hospital·N/A·NCT01141998·27 enrolled

Bed Sores1 trial

Evaluating the Impact of Vitamin D Supplementation on Healing Bed Sores in ICU.

Recruiting·MMaha Salah·Preclinical·NCT07813975·50 enrolled

Female1 trial

The Effects of Vitamin D Supplements on Sports Performance of Female Indoor Elite Athletes: a Randomized Double-blind Controlled Study

Completed·FFu Jen Catholic University Hospital·Preclinical·NCT07748650·37 enrolled

Unspecified2 trials

Is Involucrin Has a Role in Verruca Vulgaris? A Clinical and Immunohistochemical Study

Completed·—·N/A·NCT04793529·60 enrolled

AK-R215 Pharmacokinetic Study Phase I

Unknown status·AAlvogen Korea·Phase 1·NCT03321318·52 enrolled

Sources

References

[1]
ClinicalTrials.gov — 167 trial records for Cholecalciferol. U.S. National Library of Medicine, National Institutes of Health.
[2]
ChEMBL — Cholecalciferol compound record. European Bioinformatics Institute (EMBL-EBI).
[3]
Open Targets Platform — Drug–disease associations for Cholecalciferol. EMBL-EBI & Wellcome Sanger Institute.
[4]
SEC EDGAR — Hyundai Pharmaceutical Co., LTD. company filings. U.S. Securities and Exchange Commission.

Details

Drug Info

Quick Facts

Mechanism of Action: Vitamin D Receptor Agonist[2]
Modality: Small molecule[2]
Highest Phase: Phase 3[1]
Company: HHyundai Pharmaceutical Co., LTD.