Parathyroid hormone

PreclinicalSmall molecule

Parathyroid hormone is one of 19 small molecule programs targeting Postmenopausal Osteoporosis. It is currently in Preclinical.

Indications

Total Trials

Active Trials

Competitors

Pipeline

Status by Indication[3][1]

Indication

Postmenopausal OsteoporosisActive, not recruiting

Postmenopausal OsteoporosisPreclinical

Active, not recruiting

Competition

Competitive Landscape

18 competitors in Postmenopausal Osteoporosis

#DrugCompanyPhaseTrials

Zometa

Pfizer

Approved

3 2

Evista

Eli Lilly

Approved

2 3

Estrasorb

Novo Nordisk

Approved

1 4

Forteo

AAlmaject

Approved

7 5

Prolia

OOrganon and Co

Approved

6 6

Estrace

Calciferol

Boniva

CConrado Roberto Hoffmann Filho

Approved

2 9

Xylocaine

MMEDRx USA, Inc.

Approved

—10

Epsom Salt

FFresenius Kabi USA, LLC

Approved

—

Ranked by pipeline maturity and clinical activity. Current drug highlighted in teal.

Clinical

Trials by Indication[1]

Osteoporosis8 trials

Risedronate and Parathyroid Hormone to Reverse Osteoporosis Caused by Chronic Steroid Use

Completed·UUniversity of California, Davis·Phase 4·NCT00221299·60 enrolled

Effects of Parathyroid Hormone in Men With Osteoporosis

Completed·MMassachusetts General Hospital·Phase 3·NCT00000427·81 enrolled

Parathyroid Hormone (PTH) With Alendronate for Osteoporosis

Completed·—·Phase 2·NCT00005006·140 enrolled

Show 5 more trials

Sequential Treatment of Postmenopausal Women With Primary Osteoporosis (FP-001-IM)

Completed· Takeda logo

Takeda·Phase 3·NCT00365456·407 enrolled

Comparison Study of PTHrP and PTH to Treat Osteoporosis

Completed·UUniversity of Pittsburgh·Phase 2·NCT00853723·105 enrolled

Can Parathyroid Hormone Injections Reverse Glucocorticoid-induced Osteoporosis

Completed·NNational Institute of Diabetes and Digestive and Kidney Diseases (NIDDK)·Phase 2·NCT00004993

The Effect of PTH(1-84) or Alendronate on Reduction of Back Pain in Postmenopausal Women With an Osteoporosis Related Vertebral Fracture(s) (FP-005-IM)

Terminated·NNycomed·Phase 4·NCT00713258·75 enrolled

STEP: Study of Imaging Techniques (ImaTx and DXA) in Postmenopausal Women With OstEoporosis Using Preotact (FP-008-ES)

Completed·NNycomed·Phase 4·NCT00583518·129 enrolled

Infusion2 trials

One Week Comparison Study of PTH and PTHrP Infusions

Withdrawn·UUniversity of Pittsburgh·Phase 1·NCT01333267

7 Day Continuous Parathyroid Hormone IV Infusion

Completed·UUniversity of Pittsburgh·Phase 1·NCT00377312·11 enrolled

Cardiac Surgery1 trial

Treatment With PTH After Sternotomy in Cardiac Surgery Patients

Completed·UUniversity of Aarhus·Phase 3·NCT01466829·20 enrolled

Treatment1 trial

Adherence to PTH(1-84) Treatment (FP-002-IM)

Completed· Takeda logo

Takeda··NCT00478569·1,179 enrolled

Psoriasis1 trial

Treatment of Psoriasis With Parathyroid Hormone

Completed·NNational Institute of Arthritis and Musculoskeletal and Skin Diseases (NIAMS)·Phase 1/2·NCT00007306·40 enrolled

2 more indications

Postmenopausal Osteoporosis1 trial

PROPOSE Quality - PReOtact in Postmenopausal OStEoporosis - Quality of Life Study (FP-004-DE)

Completed·NNycomed··NCT00515593·110 enrolled

Transplantation1 trial

Study of Parathyroid Hormone Following Sequential Cord Blood Transplantation From an Unrelated Donor

Terminated·TThe Emmes Company, LLC·Phase 2·NCT00393380·13 enrolled

Sources

References

[1]
ClinicalTrials.gov — 15 trial records for Parathyroid hormone. U.S. National Library of Medicine, National Institutes of Health.
[2]
ChEMBL — Parathyroid hormone compound record. European Bioinformatics Institute (EMBL-EBI).
[3]
Open Targets Platform — Drug–disease associations for Parathyroid hormone. EMBL-EBI & Wellcome Sanger Institute.
[4]
SEC EDGAR — Takeda company filings. U.S. Securities and Exchange Commission.

Details

Drug Info

Quick Facts

Modality: Small molecule[2]
Highest Phase: Preclinical[1]
Company: Takeda

Parathyroid hormone

Status by Indication[3][1]

Competitive Landscape

Trials by Indication[1]

Osteoporosis8 trials

Infusion2 trials

Cardiac Surgery1 trial

Treatment1 trial

Psoriasis1 trial

Postmenopausal Osteoporosis1 trial

Transplantation1 trial

References

Drug Info

Quick Facts

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