Pilocarpine HCl

Phase 3Small molecule

AbbVie

Pilocarpine HCl is one of 7 small molecule programs targeting Presbyopia. It is currently in Phase 3.

Indications

Total Trials

Active Trials

Competitors

Pipeline

Status by Indication[3][1]

Indication

PresbyopiaCompleted

Quality of LifeRecruiting

PresbyopiaPhase 3

Completed

Quality of LifePhase 3

Recruiting

Competition

Competitive Landscape

7 competitors in Quality of Life

#DrugCompanyPhaseTrials

Tryptyr

FFalcon

Approved

1 2

Pilocarpine HCl

AbbVie

Phase 3

1 3

R-Gene 10

PPharmacia and Upjohn

Preclinical

1 4

Opioids

SSahlgrenska University Hospital

Preclinical

1 5

Sustanon 250

UUniversity of Nottingham

Phase 1

1 6

Medications

YYale University

Preclinical

Ranked by pipeline maturity and clinical activity. Current drug highlighted in teal.

Clinical

Trials by Indication[1]

Presbyopia4 trials

Safety and Efficacy Study of Pilocarpine HCl Ophthalmic Solution in Participants With Presbyopia

Not yet recruiting·CCSPC Ouyi Pharmaceutical Co., Ltd.·Phase 3·NCT06451666·330 enrolled

Efficacy Study of Pilocarpine HCl Ophthalmic Solution (AGN-190584) in Participants With Presbyopia

Completed· AbbVie logo

AbbVie·Phase 3·NCT03804268·323 enrolled

A Phase 3 Efficacy Study of Pilocarpine HCl Ophthalmic Solution (AGN-190584) in Participants With Presbyopia

Completed· AbbVie logo

AbbVie·Phase 3·NCT03857542·427 enrolled

Show 1 more trial

A Study to Assess Safety and Efficacy in Participants Age 40 to 55 With Presbyopia (Old Eye) Who Receive AGN-190584 in Both Eyes Twice Daily

Completed· AbbVie logo

AbbVie·Phase 3·NCT04983589·230 enrolled

Quality of Life1 trial

Quality of Life in Presbyopic Patients Who Are Treated With Qlosi

Recruiting·SSouthern College of Optometry·Phase 4·NCT07113210·36 enrolled

Sources

References

[1]
ClinicalTrials.gov — 5 trial records for Pilocarpine HCl. U.S. National Library of Medicine, National Institutes of Health.
[2]
ChEMBL — Pilocarpine HCl compound record. European Bioinformatics Institute (EMBL-EBI).
[3]
Open Targets Platform — Drug–disease associations for Pilocarpine HCl. EMBL-EBI & Wellcome Sanger Institute.
[4]
SEC EDGAR — AbbVie company filings. U.S. Securities and Exchange Commission.

Details

Drug Info

Quick Facts

Modality: Small molecule[2]
Highest Phase: Phase 3[1]
Company: AbbVie

Pilocarpine HCl

Status by Indication[3][1]

Competitive Landscape

Trials by Indication[1]

Presbyopia4 trials

Quality of Life1 trial

References

Drug Info

Quick Facts

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