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Opioids

ApprovedSmall molecule

SSahlgrenska University Hospital

Opioids is one of 103 small molecule programs targeting Rib Fracture. It is currently in Approved.

5

Indications

22

Total Trials

4

Active Trials

102

Competitors

Pipeline

Status by Indication[3][1]

Indication

Rib FractureActive, not recruiting

Chronic PainActive, not recruiting

HysterectomyActive, not recruiting

Inguinal HerniaActive, not recruiting

Rib FracturePreclinical

Active, not recruiting

Chronic PainPhase 2

Active, not recruiting

HysterectomyApproved

Active, not recruiting

Inguinal HerniaApproved

Active, not recruiting

Competition

Competitive Landscape

193 competitors in Chronic Pain

#DrugCompanyPhaseTrials

Opioids

SSahlgrenska University Hospital

Neurontin

VViatris Specialty LLC

Oxycodone CR

Johnson & Johnson Pharmaceutical Research & Development, L.L.C.

Zohydro Er

Naloxone Hydrochloride

PPurdue Pharma LP

Adezunap

AApurano Pharmaceuticals GmbH

BEMA Fentanyl

BBioDelivery Sciences International

MS Contin

Cymbalta

Alnylam Pharmaceuticals

Dayvigo

Ranked by pipeline maturity and clinical activity. Current drug highlighted in teal.

Timeline

Expected Milestones

Q1 2027

N/ANot yet recruiting

Pain Management

NCT03734731

Q3 2027

Post-ApprovalActive, not recruiting

Inguinal Hernia

NCT05929937

Clinical

Trials by Indication[1]

Epidural Analgesia2 trials

Intercostal Nerve Cryoablation Versus Epidural Analgesia for Nuss Repair of Pectus Excavatum

Completed·ZZuyderland Medisch Centrum·N/A·NCT05731973·50 enrolled

Supplementary Epidural Analgesia in Video-Assisted Thoracic Surgery (VATS) - The SEAVATS Study

Completed·OOdense University Hospital·Phase 4·NCT02359175·161 enrolled

Thoracic Surgery1 trial

Pectoralis and Serratus Nerves Block in Thoracic Surgery

Unknown status·SSoroka University Medical Center·Phase 2·NCT03023982·168 enrolled

Critically Ill Patients1 trial

Opioid Withdrawal Symptoms in Critically Ill Patients

Completed·MMahidol University··NCT03374722·55 enrolled

Rib Fracture1 trial

Pain as Indication for Operative Treatment of Traumatic Rib Fractures

Withdrawn·SSahlgrenska University Hospital·N/A·NCT02094807

Inguinal hernia1 trial

No Opioids vs. Minimal Opioids Following Inguinal Hernia Repair

Active, not recruiting·CClayton Petro·Phase 4·NCT05929937·904 enrolled

16 more indications

Erector Spinae Plane Block1 trial

Erector Spinae Plane Block Versus Paravertebral Block

Completed·UUniversity of Alberta·N/A·NCT03471442·48 enrolled

Surgery1 trial

Opioid-Free Orthopaedic Surgery

Completed·OOrthoCarolina Research Institute, Inc.·N/A·NCT04176783·511 enrolled

Injury1 trial

Exploring the Safety and Efficacy of Low-dose Ketamine Infusions for Pain Control in Acute Burn Injury

Withdrawn·UUniversity of Kansas Medical Center·Phase 4·NCT03095222

Treatment1 trial

Operative Treatment of Unstable Thoracic Cage Injuries and Chest Wall Deformity in Trauma

Completed·SSahlgrenska University Hospital·N/A·NCT02132416·92 enrolled

Spine Surgery1 trial

Opioid Sparing Effect of an ISP Nerve Block on Post-Op Pain Control in Posterior Cervical Spine Surgery

Recruiting·SStony Brook University·N/A·NCT06570577·60 enrolled

Dexmedetomidine1 trial

Intranasal Dexmedetomidine for Procedural Pain Management in Elderly Adults in Palliative Care

Terminated·WWalid HABRE·Phase 3·NCT03151863·33 enrolled

Head and Neck Cancer1 trial

Opioid Therapy vs Multimodal Analgesia in Head and Neck Cancer

Completed·LLondon Health Sciences Centre Research Institute OR Lawson Research Institute of St. Joseph's·Phase 2·NCT04221165·49 enrolled

Critically Ill1 trial

Signs and Symptoms of Opioid-associated Iatrogenic Withdrawal in Critically Ill Adults

Completed·—··NCT03435614·29 enrolled

Chronic pain1 trial

Project 1 Aim 2, Adaptations of the Brain in Chronic Pain With Opioid Exposure

Active, not recruiting·NNorthwestern University·Phase 2·NCT05463367·60 enrolled

Vertebral Compression Fracture1 trial

Radiofrequency Ablation: Treatment for Posterior Element Pain From Vertebral Compression Fractures

Withdrawn·UUniversity of California, Davis·Phase 4·NCT03651804

Quality of Life1 trial

Procedures of Locoregional Analgesia and Quality of Life in Palliative Care Units

Suspended·UUniversity Hospital, Limoges·N/A·NCT01094912·38 enrolled

Hysterectomy1 trial

ICE-T Pain Regimen for Total Laparoscopic Hysterectomy

Completed·MMetroHealth Medical Center·Phase 4·NCT03987022·66 enrolled

Analgesic1 trial

MAST Trial: Multi-modal Analgesic Strategies in Trauma

Completed·TThe University of Texas Health Science Center, Houston·Phase 4·NCT03472469·1,561 enrolled

Pain Management1 trial

Cannabis Vs Opioids Pain Management Objective Testing Comparisons

Not yet recruiting·AAmerican Association of Sensory Electrodiagnostic Medicine·N/A·NCT03734731·1,000 enrolled

Spinal Anesthesia1 trial

Dexmedetomine as Adjuvant for Spinal Anesthesia in Elective Cesarian Sections : a Pilot Study

Completed·SSt. Justine's Hospital·Phase 3·NCT05099055·42 enrolled

Femoral Nerve Block1 trial

Retrospective Femoral Nerve Block Study

Completed·NNationwide Children's Hospital··NCT01293136·400 enrolled

Sources

References

[1]
ClinicalTrials.gov — 22 trial records for Opioids. U.S. National Library of Medicine, National Institutes of Health.
[2]
ChEMBL — Opioids compound record. European Bioinformatics Institute (EMBL-EBI).
[3]
Open Targets Platform — Drug–disease associations for Opioids. EMBL-EBI & Wellcome Sanger Institute.
[4]
SEC EDGAR — Sahlgrenska University Hospital company filings. U.S. Securities and Exchange Commission.

Details

Drug Info

Quick Facts

Modality: Small molecule[2]
Highest Phase: Approved[1]
Company: SSahlgrenska University Hospital

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