Feldene

(Piroxicam)

ApprovedSmall molecule

PPfizer's Upjohn has merged with Mylan to form Viatris Inc.

Feldene is one of 142 small molecule programs targeting Contraception. It is currently in Approved.

Indications

Total Trials

Active Trials

141

Competitors

FDA Application

NDA/BLA/ANDA regulatory filings

Pipeline

Status by Indication[3][1]

Indication

ContraceptionActive, not recruiting

DysmenorrheaActive, not recruiting

Renal ColicActive, not recruiting

PulpitisActive, not recruiting

OsteoarthritisActive, not recruiting

ContraceptionPhase 3

Active, not recruiting

DysmenorrheaApproved

Active, not recruiting

Renal ColicPhase 3

Active, not recruiting

PulpitisPreclinical

Active, not recruiting

OsteoarthritisPhase 2

Active, not recruiting

Competition

Competitive Landscape

778 competitors in Osteoarthritis

#DrugCompanyPhaseTrials

Feldene

PPfizer's Upjohn has merged with Mylan to form Viatris Inc.

Approved

1 2

Epidiolex

Jazz Pharmaceuticals

Preclinical

4 3

Ilaris

Novartis

Preclinical

2 4

Toradol

Roche

Preclinical

1 5

Bayer Aspirin

Cataflam

Voltaren

CCerimon Pharmaceuticals

Preclinical

4 8

Glucophage

Boehringer Ingelheim

Preclinical

1 9

Precedex

MMcNeil Consumer & Specialty Pharmaceuticals, a Division of McNeil-PPC, Inc.

Preclinical

1 10

Protonix

WWyeth-Lederle Vaccines

Preclinical

Ranked by pipeline maturity and clinical activity. Current drug highlighted in teal.

Timeline

Expected Milestones

Q1 2027

Post-ApprovalNot yet recruiting

Post-Endodontic Pain

NCT07281807

Q4 2027

Phase 3Not yet recruiting

Contraception

NCT06727734

Phase 2Recruiting

Renal Colic

NCT05722782

Clinical

Trials by Indication[1]

Premedication2 trials

Piroxicam Premedication for Postendodontic Pain in Non-vital Mandibular Molars

Unknown status·—·N/A·NCT03998826·60 enrolled

Effectiveness if Premedication With Single Dose Piroxicam and Prednisolone After a Single Visit Root Canal Treatment .

Completed·—·Phase 2/3·NCT04124822·60 enrolled

Contraception2 trials

Levonorgestrel-piroxicam Versus Ulipristal Acetate for Emergency Contraception

Not yet recruiting·TThe University of Hong Kong·Phase 3·NCT06727734·980 enrolled

Piroxicam and Levonorgestrel Co-treatment for Emergency Contraception

Completed·—·Phase 2/3·NCT03614494·860 enrolled

Renal Colic2 trials

Oral NSAI Versus Paracetamol or Placebo as a Second Line Treatment for Renal Colics

Completed·UUniversity of Monastir·Phase 3·NCT02304783·1,400 enrolled

Oral NSAI Versus Acetaminophen or Placebo as a Discharge Treatment of Non Complicated Renal Colics

Recruiting·UUniversity of Monastir·Phase 2·NCT05722782·500 enrolled

Dysmenorrhea2 trials

A Comparison of Analgesic İmpacts of Piroxicam and Diclofenac Sodium in the Treatment of Primary Dysmenorrhea

Completed·PPamukkale University·Phase 4·NCT02253446·400 enrolled

A Double Blind, Double Dummy, Randomized, Comparative Study Of The Efficacy And Safety Of Valdecoxib 40 Mg Twice Daily, As Needed In The First Menstrual Cycle Day And Then Once A Day, And Piroxicam 40 Mg Once A Day In The Treatment Of Patients With Primary Dysmenorrhea

Completed· Pfizer logo

Pfizer·Phase 4·NCT00649415·154 enrolled

Third Molar Surgery1 trial

Influence of Genotype of CYP2C9 on Clinical Efficacy and Pharmacokinetics of Piroxicam After Lower Third Molar Surgery

Completed·UUniversity of Sao Paulo·Phase 4·NCT02450487·105 enrolled

7 more indications

Non-steroidal Anti-inflammatory Drugs1 trial

Interaction Between Antihypertensives and Non-Steroidal Anti-Inflammatory Drugs (NSAIDs)

Completed·UUniversity of Split·Phase 4·NCT00631514·88 enrolled

Pulpitis1 trial

Comparative Evaluation of the Effect of Prophylactic Intraligamentary Injection of Dexamethasone and Piroxicam on Postoperative Pain in Teeth With Symptomatic Irreversible Pulpitis

Unknown status·—·N/A·NCT03745105·42 enrolled

Ovulation1 trial

Effect of Piroxicam on Ovulation

Completed· Bayer logo

Bayer·Phase 2·NCT01320709·72 enrolled

Post-endodontic Pain1 trial

Comparison of the Pain Levels of Single-Dose Premedication With Piroxicam and Prednisolone on Post-Endodontic Pain in Single-Visit Root Canal Treatment of Premolars

Not yet recruiting·RRANA AHMAD·Phase 4·NCT07281807·60 enrolled

Preoperative1 trial

Comparison of Preoperative Analgesics on the Efficacy of Inferior Alveolar Nerve Block.

Completed·FFarjad Zafar·Phase 4·NCT05488925·120 enrolled

Osteoarthritis1 trial

Comparative Study of Olive Oil With Piroxicam Gel in Osteoarthritis of the Knee

Completed·—·Phase 2·NCT00670475·60 enrolled

Pain Management1 trial

Enantyum® IV Versus Piroxen® IM in Emergency Pain Management

Recruiting·RRiadh Boukef·Phase 3·NCT06404177·300 enrolled

Regulatory

FDA Approval Timeline[4]

Apr 6, 1982

FELDENE

NDA NDA018147

Sources

References

[1]
ClinicalTrials.gov — 16 trial records for Piroxicam. U.S. National Library of Medicine, National Institutes of Health.
[2]
ChEMBL — Piroxicam compound record. European Bioinformatics Institute (EMBL-EBI).
[3]
Open Targets Platform — Drug–disease associations for Piroxicam. EMBL-EBI & Wellcome Sanger Institute.
[4]
OpenFDA — FDA approval records (NDA NDA018147). U.S. Food & Drug Administration.
[5]
SEC EDGAR — Pfizer's Upjohn has merged with Mylan to form Viatris Inc. company filings. U.S. Securities and Exchange Commission.

Details

Drug Info

Quick Facts

Modality: Small molecule[2]
Highest Phase: Approved[1]
Company: PPfizer's Upjohn has merged with Mylan to form Viatris Inc.

Feldene

Status by Indication[3][1]

Competitive Landscape

Expected Milestones

Q1 2027

Q4 2027

Trials by Indication[1]

Premedication2 trials

Contraception2 trials

Renal Colic2 trials

Dysmenorrhea2 trials

Third Molar Surgery1 trial

Non-steroidal Anti-inflammatory Drugs1 trial

Pulpitis1 trial

Ovulation1 trial

Post-endodontic Pain1 trial

Preoperative1 trial

Osteoarthritis1 trial

Pain Management1 trial

FDA Approval Timeline[4]

References

Drug Info

Quick Facts

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