propofol and remifentanil

PreclinicalSmall molecule

propofol and remifentanil is one of 25 small molecule programs targeting Total Intravenous Anesthesia. It is currently in Preclinical.

Indications

Total Trials

Active Trials

Competitors

Pipeline

Status by Indication[3][1]

Indication

Total Intravenous AnesthesiaCompleted

Elderly PatientsCompleted

Total Intravenous AnesthesiaPreclinical

Completed

Elderly PatientsPreclinical

Completed

Competition

Competitive Landscape

24 competitors in Elderly Patients

#DrugCompanyPhaseTrials

Decadron

AAspen Global Incorporated

Approved

5 2

Rituxan

Roche

Phase 3

4 3

Venclexta

AbbVie

Phase 3

4 4

Revlimid

KKaruna Therapeutics, Inc., a Bristol Myers Squibb company

Phase 3

3 5

Cytosar

Teva

Phase 2

2 6

Polivy

Roche

Phase 2

1 7

Azulfidine

Pfizer

Phase 2

1 8

Opdivo

Bristol-Myers Squibb

Phase 2

1 9

Vidaza

KKaruna Therapeutics, Inc., a Bristol Myers Squibb company

Phase 2

3 10

Temodar

CCidara Therapeutics Inc., a subsidiary of Merck & Co., Inc. (Rahway, New Jersey USA)

Phase 2

Ranked by pipeline maturity and clinical activity. Current drug highlighted in teal.

Clinical

Trials by Indication[1]

Remifentanil2 trials

Propofol for Supreme LMA Insertion With and Without Remifentanil

Completed·HHospital General Universitario Gregorio Marañon·Phase 4·NCT01974648·59 enrolled

Comparison of Different Propofol Formulations With or Without Remifentanil

Completed·HHopital Foch·Phase 4·NCT01592162·409 enrolled

Total Intravenous Anesthesia2 trials

The Comparison of Changes of QTc, Tp-e Interval, and Tp-e/QT Ratio, Tp-e/QTc Ratio on the ECG During Robotic-assisted Laparoscopic Radical Prostatectomy Under Sevoflurane, Desflurane and Total Intravenous Anesthesia -Randomized Controlled Trial

Completed·YYonsei University·N/A·NCT03539003·69 enrolled

Study on Gynecological Laparoscopy Under Total Intravenous Anesthesia

Completed·WWuhan Children's Hospital·N/A·NCT06524596·59 enrolled

Randomized Controlled Trial2 trials

Effect of Anesthesia on Quality of Recovery in Patients Undergoing Correctional Tibial Osteotomy - A Randomized Controlled Trial

Completed·YYonsei University·N/A·NCT02826902·76 enrolled

Randomized Controlled Trial to Evaluate of Dexmedetomidine for the Effect on Operative Visibility in Patients Undergoing Endoscopic Sinus Surgery

Completed·YYonsei University·Phase 4·NCT01569048·66 enrolled

Acute Postoperative Pain1 trial

Propofol Versus Sevoflurane on Acute Postoperative Pain

Completed·YYeungnam University College of Medicine·N/A·NCT04333992·48 enrolled

Laparoscopic Surgery1 trial

Interaction of Sevoflurane Propofol and Remifentanil in Anesthesia for Laparoscopic Surgery

Completed·IInsel Gruppe AG, University Hospital Bern·Phase 4·NCT02457442·172 enrolled

1 more indication

Elderly Patients1 trial

Effect of Dexmedetomidine on Recovery Profiles of Elderly Patients

Completed·—·N/A·NCT01851005·120 enrolled

Sources

References

[1]
ClinicalTrials.gov — 9 trial records for propofol and remifentanil. U.S. National Library of Medicine, National Institutes of Health.
[2]
ChEMBL — propofol and remifentanil compound record. European Bioinformatics Institute (EMBL-EBI).
[3]
Open Targets Platform — Drug–disease associations for propofol and remifentanil. EMBL-EBI & Wellcome Sanger Institute.
[4]
SEC EDGAR — Yonsei University company filings. U.S. Securities and Exchange Commission.

Details

Drug Info

Quick Facts

Modality: Small molecule[2]
Highest Phase: Preclinical[1]
Company: YYonsei University

propofol and remifentanil

Status by Indication[3][1]

Competitive Landscape

Trials by Indication[1]

Remifentanil2 trials

Total Intravenous Anesthesia2 trials

Randomized Controlled Trial2 trials

Acute Postoperative Pain1 trial

Laparoscopic Surgery1 trial

Elderly Patients1 trial

References

Drug Info

Quick Facts

Related News