Protamine sulfate

PreclinicalSmall molecule

LLondon Health Sciences Centre Research Institute OR Lawson Research Institute of St. Joseph's

Protamine sulfate is one of 6 small molecule programs targeting Cardiopulmonary Bypass. It is currently in Preclinical.

Indications

Total Trials

Active Trials

Competitors

Pipeline

Status by Indication[3][1]

Indication

Cardiopulmonary BypassNot yet recruiting

Cardiopulmonary BypassPreclinical

Not yet recruiting

Competition

Competitive Landscape

7 competitors in Cardiopulmonary Bypass

#DrugCompanyPhaseTrials

Nitric Oxide Gas

XXijing Hospital

Phase 3

1 2

Primacor

Sanofi

Preclinical

2 3

Versed

CConrado Roberto Hoffmann Filho

Preclinical

1 4

Aprotinin

Bayer

Preclinical

1 5

Dibenzyline

AAdvanz Pharma

Preclinical

1 6

Protamine sulfate

LLondon Health Sciences Centre Research Institute OR Lawson Research Institute of St. Joseph's

Preclinical

Ranked by pipeline maturity and clinical activity. Current drug highlighted in teal.

Clinical

Trials by Indication[1]

Cardiopulmonary Bypass1 trial

Dose for Reversal of Heparin After Cardiopulmonary Bypass

Not yet recruiting·SSohag University·N/A·NCT07477977·195 enrolled

Atrial Fibrillation1 trial

Use of Protamine for Heparin Reversal After Catheter Ablation of Atrial Fibrillation

Completed·UUniversity of Michigan·Phase 4·NCT03140631·153 enrolled

Cardiac Surgery1 trial

Systematic Evaluation of Protamine Doze in Cardiac Surgery

Unknown status·LLondon Health Sciences Centre Research Institute OR Lawson Research Institute of St. Joseph's·N/A·NCT03787641·100 enrolled

Catheter1 trial

Protamine Sulfate During Transcatheter Aortic Valve Implantation

Completed·MMedical University of Warsaw·Phase 4·NCT02974660·100 enrolled

Complication1 trial

Routine Versus Selective Protamine Administration to Reduce Bleeding Complications After Transcatheter Aortic Valve Implantation (POPular ACE TAVI)

Recruiting·SSt. Antonius Hospital·Phase 4·NCT05774691·1,000 enrolled

Sources

References

[1]
ClinicalTrials.gov — 5 trial records for Protamine sulfate. U.S. National Library of Medicine, National Institutes of Health.
[2]
ChEMBL — Protamine sulfate compound record. European Bioinformatics Institute (EMBL-EBI).
[3]
Open Targets Platform — Drug–disease associations for Protamine sulfate. EMBL-EBI & Wellcome Sanger Institute.
[4]
SEC EDGAR — London Health Sciences Centre Research Institute OR Lawson Research Institute of St. Joseph's company filings. U.S. Securities and Exchange Commission.

Details

Drug Info

Quick Facts

Modality: Small molecule[2]
Highest Phase: Preclinical[1]
Company: LLondon Health Sciences Centre Research Institute OR Lawson Research Institute of St. Joseph's

Protamine sulfate

Status by Indication[3][1]

Competitive Landscape

Trials by Indication[1]

Cardiopulmonary Bypass1 trial

Atrial Fibrillation1 trial

Cardiac Surgery1 trial

Catheter1 trial

Complication1 trial

References

Drug Info

Quick Facts

Related News