statins

Pipeline

Status by Indication[3][1]

Competition

Competitive Landscape

COVID-19MelanomaIschemic StrokeMyocardial InfarctionAcute Coronary SyndromePeripheral Arterial DiseaseCardiovascular

317 competitors in COVID-19

#DrugCompanyPhaseTrials

1

Stivarga

Bayer

Preclinical

12

Aimovig

Amgen

Preclinical

13

Aldactone

Pfizer

Preclinical

14

Nexavar

Bayer

Preclinical

15

Calciferol

Jazz Pharmaceuticals

Preclinical

—6

Activella

Eli Lilly

Preclinical

—7

Angiomax

BBaxter Healthcare Corporation

Preclinical

28

Tricor

JJagotec

Preclinical

19

Precedex

MMcNeil Consumer & Specialty Pharmaceuticals, a Division of McNeil-PPC, Inc.

Preclinical

110

Benadryl

PParkedale

Preclinical

1Show 39 more competitors

Ranked by pipeline maturity and clinical activity. Current drug highlighted in teal.

Timeline

Expected Milestones

Clinical

Trials by Indication[1]

Statins2 trials

Statins and ARBs on Rheumatoid Activity

Recruiting·SSherief Abd-Elsalam·Phase 3·NCT03770702·45 enrolled

Differential Metabolic Effects of Statins

Completed·GGachon University Gil Medical Center··NCT00546559

Efficacy and Safety1 trial

Efficacy and Safety of PRC-4016 in Subjects With Mixed Dyslipidemia

Terminated·PPronova BioPharma·Phase 2·NCT01972178·113 enrolled

Myopathy1 trial

Quality of Life in Patients With Statin-Associated Myopathy

Terminated·RRockefeller University·Phase 4·NCT00850460·14 enrolled

Type 2 Diabetes1 trial

Efficacy and Safety of Alirocumab Versus Usual Care on Top of Maximally Tolerated Statin Therapy in Patients With Type 2 Diabetes and Mixed Dyslipidemia (ODYSSEY DM-Dyslipidemia)

Completed·Sanofi·Phase 4·NCT02642159·413 enrolled

Hypercholesterolemia1 trial

Randomized Parallel Group Trial Of The Efficacy And Safety Of Ezetimibe With A Statin Versus Statin Dose Doubling In Patients With Persistent Primary Hypercholesterolemia (0653-152)(COMPLETED)

Completed·OOrganon and Co·Phase 4·NCT00652847·1,140 enrolled

16 more indications

Peripheral Arterial Disease1 trial

Safety and Efficacy Study of Bosentan for Intermittent Claudication in Peripheral Arterial Disease

Completed·HHospital Universitario Getafe·N/A·NCT01738542·30 enrolled

Breast Cancer1 trial

Survival Benefits of Statins in Breast Cancer Patients

Unknown status·PPeking Union Medical College Hospital·Phase 3·NCT03971019·314 enrolled

COVID-191 trial

Cardiovascular Risk Factors and Severe COVID-19. A Nationwide Registry-based Case-Control Study

Unknown status·KKarolinska Institutet··NCT04426084·22,784 enrolled

Acute Coronary Syndrome1 trial

Prior Statin Use and Risk of CHF, ALO and Malignant Arrhythmia in Indonesian Post-Acute Coronary Syndrome Patients

Completed·TTarumanagara University··NCT03596931·130 enrolled

Elevated Cholesterol1 trial

Safety, Pharmacokinetics and Pharmacodynamics of LGT209 in Healthy Volunteers With Elevated Cholesterol and in Hypercholesterolemic Patients Treated With Statins

Completed·Novartis·Phase 1·NCT01859455·25 enrolled

Cognitive impairment1 trial

Dapagliflozin Effect in Cognitive Impairment in Stroke Trial

Unknown status·JJaime Daniel Mondragon·Phase 2/3·NCT05565976·270 enrolled

Anemia1 trial

Different Treatment Modalities in the Management of the Painful Crisis in Pediatric Sickle- Cell Anemia

Completed·—·Phase 2/3·NCT04301336·350 enrolled

Renal Transplant Recipients1 trial

Lipid Management in Renal Transplant Recipients Using Evolocumab.

Unknown status·—·Phase 4·NCT04608474·120 enrolled

Myocardial Infarction1 trial

Targeting Investigation and Treatment in Patients With Type 2 Myocardial Infarction

Completed·UUniversity of Edinburgh·N/A·NCT05419583·60 enrolled

Chronic Coronary Syndrome1 trial

Chronic Coronary Syndrome Real Practice and Guidelines

Active, not recruiting·—··NCT06684366·300 enrolled

Safety and Efficacy1 trial

A Study to Evaluate the Safety and Efficacy of the PCSK9 Inhibitor AK102 in Patients With HoFH

Completed·AAkeso·Phase 2·NCT03933293·10 enrolled

Hemorrhage1 trial

Statins In Intracerbral Hemorrhage

Recruiting·—·Phase 3·NCT03936361·1,456 enrolled

Cardiovascular1 trial

Cardiovascular Magnetic Resonance for the Occluded Infarct-Related Artery Treatment

Terminated·NNational Institute of Cardiology, Warsaw, Poland·N/A·NCT00968383·11 enrolled

Ischemic stroke1 trial

Short-term Effect of PCSK9 Inhibitor in Patients With Acute Ischemic Stroke

Unknown status·XXuanwu Hospital, Beijing··NCT06134635·80 enrolled

Familial Hypercholesterolemia1 trial

An 8-Week Dose-Finding Study to Evaluate the Efficacy and Safety of Alirocumab in Children and Adolescents With Heterozygous Familial Hypercholesterolemia

Completed·Sanofi·Phase 2·NCT02890992·42 enrolled

Melanoma1 trial

Lipid Lowering Therapy for Atherosclerotic Disease in Melanoma Patients Receiving Immune Checkpoint Inhibitors

Recruiting·UUniversity of Colorado, Denver·Preclinical·NCT07704918·40 enrolled

Details

Drug Info

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