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Gastroenterology/Chronic Pancreatitis

Gastroenterology

Chronic Pancreatitis

11

Pipeline Programs↗

21

Active Trials↗

12

Companies Involved↗

Chronic Pancreatitis is an emerging landscape with 11 programs across 12 companies.

Intelligence

Pipeline Metrics

Competitive Density

47/100

Pipeline Velocity

27/100

Mech. Concentration

25/100

Completion Rate

66/100

Attrition Rate

20/100

Pipeline

Programs by Phase

Preclinical9

Ivacaftor

Vertex Pharmaceuticals

Meperidine

Quagen

Buprenorphine

Indivior Inc.

Aspirin

Bayer

Morphine

Hikma Pharmaceuticals LLC

Phase 12

Paricalcitol

AbbVie

Lacosamide

UCB

Phase 2

No programs

Phase 3

No programs

Approved

No programs

Analysis

Trial Status

54

clinical trials

Completed21 · 39%

Recruiting11 · 20%

Terminated8 · 15%

Active, not recruiting5 · 9%

Not yet recruiting5 · 9%

Withdrawn3 · 6%

Other1 · 2%

Clinical Trials

Trial Activity

54 trials

A Study on the Changes of Glucose Metabolism and Exocrine Function in Patients With Chronic Pancreatitis

Recruiting·SShanghai Changzheng Hospital·Phase 1·NCT07314489·80 enrolled

STTEPP: Safety, Tolerability and Dose Limiting Toxicity of Lacosamide in Patients With Painful Chronic Pancreatitis

Recruiting·IIndiana University·Phase 1·NCT05603702·24 enrolled

Novel Cellular Therapy for the Treatment of Pain Associated With Chronic Pancreatitis

Recruiting·VVA Office of Research and Development·Phase 1·NCT05925036·40 enrolled

Metformin in Post Chronic Pancreatitis Diabetes Mellitus

Recruiting·—·Phase 4·NCT06937294·58 enrolled

Safety and Efficacy of Mesenchymal Stem Cells Associated With Chronic Pancreatitis Pain

Recruiting·MMedical University of South Carolina·Phase 1·NCT06205342·48 enrolled

Endotherapy and/or Extracorporeal Shockwave Lithotripsy for Painless Chronic Pancreatitis

Recruiting·—·N/A·NCT07074379·126 enrolled

QST Study: Predicting Treatment Response in Chronic Pancreatitis Using Quantitative Sensory Testing

Recruiting·—·Preclinical·NCT03434392·500 enrolled

Pancreatic Quantitative Sensory Testing (P-QST) to Predict Treatment Response for Pain in Chronic Pancreatitis

Recruiting·UUniversity of Pittsburgh·Preclinical·NCT04996628·150 enrolled

Pediatric Longitudinal Cohort Study of Chronic Pancreatitis (INSPPIRE 2)

Recruiting·MM.D. Anderson Cancer Center·N/A·NCT06651580·1,600 enrolled

Malabsorption Blood Test (MBT) to Determine Exocrine Pancreatic Function and Related Quality of Life in Chronic Pancreatitis

Recruiting·—·Approved·NCT07418593·80 enrolled

EVALUATION OF THE RELATIONSHIP BETWEEN NEURAL SENSITISATION AND NEUROPSYCHOLOGICAL ALTERATIONS IN PATIENTS WITH PAINFUL CHRONIC PANCREATITIS

Recruiting·AAsian Institute of Gastroenterology, India·N/A·NCT07707609·200 enrolled

An Observational Study on Post-chronic Pancreatitis Diabetes Mellitus

Active, not recruiting·—·N/A·NCT05764629·324 enrolled

Ivacaftor Impact in an Adolescent Without a Cystic Fibrosis-Associated CFTR (Cystic Fibrosis Transmembrane Conductance Regulator) Mutation for Chronic Pancreatitis: Single-Patient Study Tracking Flare Frequency and Health Data Compared to Historical Records.

Active, not recruiting·—·N/A·NCT07022327·1 enrolled

Autologous Mesenchymal Stromal Cells and Islet Co-transplantation to Enhance Islet Survival and Function in Chronic Pancreatitis Patients Undergo Total Pancreatectomy and Islet Autotransplantation

Active, not recruiting·MMedical University of South Carolina·Phase 1·NCT05095532·42 enrolled

A PiLot ClinicaL TrIal of ParicAlcitol for ChroNiC PancrEatitis

Active, not recruiting·CCedars-Sinai Medical Center·Phase 1·NCT05664880·24 enrolled

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Data sources: ClinicalTrials.gov (NIH) · OpenFDA (FDA) · ChEMBL (EMBL-EBI) · Open Targets (EBI/Sanger) · MedlinePlus (NIH) · PubMed (NIH) · SEC EDGAR (SEC)