VivoSeq
Other

Critically Ill

2

Pipeline Programs↗

8

Active Trials↗

3

Companies Involved↗

Critically Ill is an early-stage landscape with 2 programs across 3 companies. The most active players are Fresenius Kabi Oncology Ltd., AstraZeneca, GSK. 2 programs are in Phase 3.

Intelligence

Pipeline Metrics

Competitive Density

29/100

Pipeline Velocity

19/100

Mech. Concentration

100/100

Completion Rate

77/100

Attrition Rate

16/100

Competition

Competitive Landscape

Bubble size = clinical trials

Approved
Phase 3
Phase 2
Phase 1
Preclinical

Key Players

Top Companies Companies ranked by the number of pipeline programs they run for this disease.

F

Fresenius Kabi Oncology Ltd.

1 program

Phase 3AstraZeneca logo

AstraZeneca

0 programs

PreclinicalGSK logo

GSK

0 programs

Preclinical

Pipeline

Programs by Phase

Preclinical
No programs
Phase 1
No programs
Phase 2
No programs
Phase 32

Ketofol

Tanta University

Propofol

Fresenius Kabi Oncology Ltd.

Approved
No programs

Analysis

Trial Status

44

clinical trials

Completed23 · 52%
Recruiting6 · 14%
Unknown status6 · 14%
Terminated4 · 9%
Withdrawn3 · 7%
Not yet recruiting2 · 5%

Clinical Trials

Trial Activity

44 trials

Opportunistic PK/PD Trial in Critically Ill Children (OPTIC)
Recruiting·—·N/A·NCT05055830·2,000 enrolled
Bone Loss Prevention With Zoledronic Acid or Denosumab in Critically Ill Adults
Recruiting·—·Phase 2·NCT04608630·450 enrolled
Effects of Early Testosterone Gel Administration on Physical Performance in the Critically Ill
Recruiting·UUniversity Hospital, Clermont-Ferrand·Phase 2·NCT05825092·600 enrolled
CReep and Maintenance flUid Sodium Chloride ADministration rEduction in cRitically Ill adultS
Recruiting·UUniversity Hospital, Antwerp·Phase 4·NCT07189091·640 enrolled
Comparative Efficacy and Safety of Propofol-Ketamine Combination Versus Propofol Monotherapy in Geriatric Patients Under Invasive Ventilation
Recruiting·HHelwan University·Phase 3·NCT07530146·41 enrolled
Transducer Levelling Errors in Everyday ICU Practice - A Multicentre Blinded Observational Study
Recruiting·—·N/A·NCT07330505·60 enrolled
Precision Dosing of Beta-lactam Antibiotics in Critically Ill Children
Not yet recruiting·UUniversity Hospital, Ghent·Phase 4·NCT06929702·58 enrolled
Red Blood Cell Transfusion to Optimize Extubation: a Randomized Controlled Trial
Not yet recruiting·AAssistance Publique - Hôpitaux de Paris·Preclinical·NCT07499492·800 enrolled
Critically Ill ICU Patients Under Casirivimab- and/or Tocilizumab Application
Completed·UUniversity of Ulm·N/A·NCT06233357·95 enrolled
Impact of Gabapentin on Slow Wave Sleep in Adult Critically Ill Patient
Completed·MMahidol University·N/A·NCT04818450·60 enrolled
Non-invasive Ventilation and Dex in Critically Ill Adults
Completed·SSt. Joseph's Healthcare Hamilton·Phase 3·NCT04878510·24 enrolled
Pharmacokinetic and Pharmacodynamic Evaluation of Doripenem in Critically Ill Trauma Patients
Completed·EEmory University·Phase 4·NCT01027897·30 enrolled
The Association of Vitamin D Supplementation With the Outcome in Critically Ill Children
Completed·—·Phase 4·NCT04536831·96 enrolled
Intravenous Fish Oil in Critically Ill Cardiac Patients
Completed·—·Phase 3·NCT00516178·31 enrolled
Pilot Study of the Safety of a Daily Ethanol Lock for Urinary Catheters in Critically Ill Children
Completed·CChildren's Healthcare of Atlanta·Phase 1·NCT01865708·10 enrolled
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Data sources: ClinicalTrials.gov (NIH) · OpenFDA (FDA) · ChEMBL (EMBL-EBI) · Open Targets (EBI/Sanger) · MedlinePlus (NIH) · PubMed (NIH) · SEC EDGAR (SEC)