Isotonic

PreclinicalSmall molecule

IIstanbul University

Isotonic is one of 3 small molecule programs targeting Critically Ill. It is currently in Preclinical.

Indications

Total Trials

Active Trials

Competitors

Pipeline

Status by Indication[3][1]

Indication

Critically IllCompleted

Critically IllPreclinical

Completed

Competition

Competitive Landscape

3 competitors in Critically Ill

#DrugCompanyPhaseTrials

Reglan

IIstituto Clinico Humanitas

Preclinical

2 2

Androgel

RRepros Therapeutics Inc.

Phase 2

1 3

Isotonic

IIstanbul University

Preclinical

Ranked by pipeline maturity and clinical activity. Current drug highlighted in teal.

Timeline

Expected Milestones

Q4 2029

Phase 2Recruiting

Depression

NCT06400121

Clinical

Trials by Indication[1]

Coronary Artery Bypass1 trial

Hypertonic Solution in Off Pump Coronary Artery Bypass Graft Surgery

Unknown status·HHospital Pitangueiras·Phase 4·NCT01463917·20 enrolled

Critically Ill1 trial

0.9% NaCl/Dextrose 5% vs 0.45% NaCl/Dextrose 5% as Maintenance Intravenous Fluids in Critically Ill Children

Completed·HHospital General de Niños Pedro de Elizalde·N/A·NCT01301274·66 enrolled

Postoperative Analgesia1 trial

Ondansetron's Opposite Effect on Postoperative Analgesia of Acetaminophen

Completed·MMustafa Kemal University·Phase 4·NCT02296333·80 enrolled

Chronic pain1 trial

Acetaminophen for Chronic Pain in Hysterectomy

Completed·MMustafa Kemal University·Phase 4·NCT02086747·140 enrolled

Spinal Surgery1 trial

The Comparison of Analgesia Methods Used for Spinal Surgery

Unknown status·IIstanbul University·N/A·NCT04603638·82 enrolled

5 more indications

Intravenous Lidocaine1 trial

Effects of Intravenous Lidocaine Associated With Magnesium Sulfate on the Cisatracurium-Induced Neuromuscular Block

Completed·UUniversity of Sao Paulo·Phase 4·NCT02483611·48 enrolled

Bronchiolitis1 trial

Nasal Irrigation in Infants With Bronchiolitis.

Completed·IIRCCS Burlo Garofolo·Phase 3·NCT02162745·133 enrolled

Local Anesthetic1 trial

Comparison of Different Local Anesthetic Dose in Suprascapular and Axillary Blocks in Shoulder Arthroscopies

Completed·IIstanbul University·N/A·NCT04947007·132 enrolled

Hemodynamic1 trial

Comparison of Hemodynamic Results of Two Different Fluid Managements

Unknown status·IIstanbul University·N/A·NCT05733403·40 enrolled

Depression1 trial

Phase 2, Randomized, Double-Blind, Placebo-Controlled, Single Intravenous Dose, Parallel Efficacy Study of Apimostinel With or Without Subsequent Automated Self-Association Training in Subjects With Major Depressive Disorder

Recruiting·RRebecca Price·Phase 2·NCT06400121·150 enrolled

Sources

References

[1]
ClinicalTrials.gov — 10 trial records for Isotonic. U.S. National Library of Medicine, National Institutes of Health.
[2]
ChEMBL — Isotonic compound record. European Bioinformatics Institute (EMBL-EBI).
[3]
Open Targets Platform — Drug–disease associations for Isotonic. EMBL-EBI & Wellcome Sanger Institute.
[4]
SEC EDGAR — Istanbul University company filings. U.S. Securities and Exchange Commission.

Details

Drug Info

Quick Facts

Modality: Small molecule[2]
Highest Phase: Preclinical[1]
Company: IIstanbul University

Isotonic

Status by Indication[3][1]

Competitive Landscape

Expected Milestones

Q4 2029

Trials by Indication[1]

Coronary Artery Bypass1 trial

Critically Ill1 trial

Postoperative Analgesia1 trial

Chronic pain1 trial

Spinal Surgery1 trial

Intravenous Lidocaine1 trial

Bronchiolitis1 trial

Local Anesthetic1 trial

Hemodynamic1 trial

Depression1 trial

References

Drug Info

Quick Facts

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