VivoSeq
Musculoskeletal

Femur Fracture

22

Pipeline Programs↗

2

Active Trials↗

12

Companies Involved↗

Femur Fracture is an emerging landscape with 22 programs across 12 companies. The most active players are EMD Serono, TLC Biopharmaceuticals, Inc., Shanghai Hengrui Pharmaceutical Co., Ltd.. 5 therapies are approved with 1 more in late-stage development.

Intelligence

Pipeline Metrics

Competitive Density

48/100

Pipeline Velocity

6/100

Mech. Concentration

17/100

Completion Rate

46/100

Attrition Rate

32/100

Competition

Competitive Landscape

Bubble size = clinical trials

Approved
Phase 3
Phase 2
Phase 1
Preclinical

Key Players

Top Companies Companies ranked by the number of pipeline programs they run for this disease.

EMD Serono logo

EMD Serono

1 program

Phase 1T

TLC Biopharmaceuticals, Inc.

1 program

Phase 2Shanghai Hengrui Pharmaceutical Co., Ltd. logo

Shanghai Hengrui Pharmaceutical Co., Ltd.

1 program

Phase 2A

Almaject

1 program

Phase 3F

Fresenius Kabi Oncology Ltd.

1 program

ApprovedH

Hikma Pharmaceuticals LLC

1 program

Approved

Pipeline

Programs by Phase

Analysis

Modality Breakdown

93%

Small molecule

26 of 28 classified programs — the dominant modality here.

7%ALL OTHERSPeptide27%

Small molecule leads; the ring shows all 28 classified programs, each share of the total. Modality classified for 100% of 28 pipeline programs.

Analysis

Trial Status

22

clinical trials

Unknown status7 · 32%
Completed6 · 27%
Terminated5 · 23%
Withdrawn2 · 9%
Enrolling by invitation1 · 5%
Recruiting1 · 5%

Clinical Trials

Trial Activity

22 trials

Comparison of EOSP Between Usg Guided S-FICB vs USG Guided PENG Block in Pts Undergoing Femur Fracture Surgery
Recruiting·SSahiwal medical college sahiwal·Phase 2/3·NCT06568770·70 enrolled
Intertrochanteric Femur Fracture Patients Who Receive Metformin With a Placebo
Enrolling by invitation·UUniversity of Utah·Phase 1·NCT07179042·60 enrolled
Fascia Iliaca Compartment Block for Proximal-end Femur Fractures
Completed·MMansoura University·N/A·NCT02696915·60 enrolled
Effect of Teriparatide on Fracture Healing in Patients With Incomplete Atypical Femur Fractures
Completed·UUniversity Health Network, Toronto·Phase 3·NCT01896011·34 enrolled
Efficacy of Peri-Incisional Multimodal Drug Injection Following Operative Management of Femur Fractures
Completed·UUniversity of Iowa·Phase 4·NCT02793947·102 enrolled
Analgesia For Positioning Patient With Femur Fracture For Spinal Anaesthesia
Completed·—·N/A·NCT02983344·24 enrolled
Analgesic Effect of Paracetamol in Patients With Femur Fracture: is Intravenous Better Than Oral?
Completed·FFondazione Policlinico Universitario Agostino Gemelli IRCCS·N/A·NCT05025228·170 enrolled
Peripheral Nerve Blocks vs Selective Spinal Anesthesia in Patients With Femur Fracture
Completed·FFederico II University·N/A·NCT06155903·78 enrolled
Efficacy Study of Femoral Nerve Block in Children With a Femur Fracture
Terminated·WWashington University School of Medicine·N/A·NCT01294098·2 enrolled
Anesthesia And Post-operative Mortality After Proximal Femur Fractures
Terminated·—·N/A·NCT02406300·57 enrolled
Trial of Ultrasound Guided Femoral Nerve Block on Isolated Femur Fracture Using Echo Friendly Needles
Terminated·TThe University of Texas Health Science Center, Houston·Phase 4·NCT02046317·12 enrolled
Femoral Nerve Block for Femur Fracture Repair in Pediatrics
Terminated·NNationwide Children's Hospital·Phase 2·NCT01759407·19 enrolled
Effects of Liposomal Bupivacaine for Acute Pain in Hip and Femur Fractures
Terminated·—·Phase 2·NCT02679560·3 enrolled
The Effect of Tranexamic Acid on Blood Loss and Transfusion Requirements Following Open Femur Fracture Surgery
Withdrawn·TThe University of Texas Health Science Center, Houston·Phase 4·NCT03679481
Supracondylar Distal Femur Fractures and Abaloparatide
Withdrawn·—·Phase 4·NCT04626141
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Data sources: ClinicalTrials.gov (NIH) · OpenFDA (FDA) · ChEMBL (EMBL-EBI) · Open Targets (EBI/Sanger) · MedlinePlus (NIH) · PubMed (NIH) · SEC EDGAR (SEC)