VivoSeq
Other

Propofol

2

Pipeline Programs↗

7

Active Trials↗

6

Companies Involved↗

Propofol is an early-stage landscape with 2 programs across 6 companies. The most active players are McNeil Consumer & Specialty Pharmaceuticals, a Division of McNeil-PPC, Inc., Fresenius Kabi Oncology Ltd., Haisco Pharmaceutical Group Co., Ltd.. 2 therapies are approved.

Intelligence

Pipeline Metrics

Competitive Density

28/100

Pipeline Velocity

11/100

Mech. Concentration

50/100

Completion Rate

98/100

Attrition Rate

2/100

Competition

Competitive Landscape

Bubble size = clinical trials

Approved
Phase 3
Phase 2
Phase 1
Preclinical

Key Players

Top Companies Companies ranked by the number of pipeline programs they run for this disease.

M

McNeil Consumer & Specialty Pharmaceuticals, a Division of McNeil-PPC, Inc.

1 program

ApprovedF

Fresenius Kabi Oncology Ltd.

1 program

ApprovedHaisco Pharmaceutical Group Co., Ltd. logo

Haisco Pharmaceutical Group Co., Ltd.

0 programs

PreclinicalEisai logo

Eisai

0 programs

PreclinicalJ

Jiangsu Nhwa Pharmaceutical Co., Ltd.

0 programs

PreclinicalF

Fresenius

0 programs

Preclinical

Pipeline

Programs by Phase

Preclinical
No programs
Phase 1
No programs
Phase 2
No programs
Phase 3
No programs
Approved2

Dexmedetomidine

McNeil Consumer & Specialty Pharmaceuticals, a Division of McNeil-PPC, Inc.

Propofol

Fresenius Kabi Oncology Ltd.

Analysis

Trial Status

63

clinical trials

Completed51 · 81%
Recruiting6 · 10%
Unknown status4 · 6%
Active, not recruiting1 · 2%
Withdrawn1 · 2%

Clinical Trials

Trial Activity

63 trials

Re-evaluation of the Effect Site Model of the PKPD Propofol Eleveld Model
Recruiting·UUniversidad del Desarrollo·Phase 4·NCT06417645·24 enrolled
Antidepressant Response of DMT Masked With Propofol
Recruiting·UUniversity Hospital, Basel, Switzerland·N/A·NCT06927076·112 enrolled
Etomidate Versus Propofol in CABG Surgery
Recruiting·HHartford Hospital·Phase 4·NCT06068764·300 enrolled
Propofol vs Sevo for Paediatric Tumor Surgery
Recruiting·HHong Kong Children's Hospital·Phase 4·NCT04475705·100 enrolled
Propofol and Etomidate Admixtures Comparisons Trial (PEAC Trial)
Recruiting·UUniversity of Texas Southwestern Medical Center·Phase 3·NCT05358535·200 enrolled
Effect of Mannitol on Propofol Level
Recruiting·—·Phase 4·NCT06884657·40 enrolled
Neural and Antidepressant Effects of Propofol
Active, not recruiting·UUniversity of Utah·Phase 2/3·NCT03684447·48 enrolled
Propofol Pharmacokinetics and Pharmacodynamics Modelling
Completed·—·N/A·NCT02713698·60 enrolled
Preventing Propofol-associated Injection Pain
Completed·—·Phase 4·NCT00864682·156 enrolled
Bioequivalence Study of Propofol Medium and Long Chain Fat Emulsion Injection in Healthy Chinese Subjects
Completed·Haisco Pharmaceutical Group Co., Ltd. logoHaisco Pharmaceutical Group Co., Ltd.·Phase 1·NCT07057609·36 enrolled
A Study to Assess the Transfer of Fospropofol and Its Active Metabolite, Propofol, to Breast Milk Following Administration of LUSEDRA to Lactating Women Undergoing a Needed Procedure
Completed·Eisai logoEisai·Phase 1·NCT01309984·10 enrolled
Effect of Desflurane v/s Propofol on the Optic Nerve Sheath Diameter
Completed·—·Phase 4·NCT07359508·146 enrolled
Use of a Modified Propofol Emulsion in Adults
Completed·BB. Braun Melsungen AG·Phase 3·NCT00690495·100 enrolled
Effects of Propofol on Early Recovery of Hunger After Surgery
Completed·UUniversity Hospital, Rouen·Phase 4·NCT02272166·116 enrolled
the Effect Site Equilibration Time of Propofol is Age Dependant
Completed·UUniversidad del Desarrollo·Phase 4·NCT01586013·45 enrolled
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Data sources: ClinicalTrials.gov (NIH) · OpenFDA (FDA) · ChEMBL (EMBL-EBI) · Open Targets (EBI/Sanger) · MedlinePlus (NIH) · PubMed (NIH) · SEC EDGAR (SEC)