VivoSeq
Other

Sleep

7

Pipeline Programs↗

25

Active Trials↗

22

Companies Involved↗

Sleep is an early-stage landscape with 7 programs across 22 companies. The most active players are Eli Lilly, Eisai, Cidara Therapeutics Inc., a subsidiary of Merck & Co., Inc. (Rahway, New Jersey USA). 3 therapies are approved with 1 more in late-stage development.

Intelligence

Pipeline Metrics

Competitive Density

45/100

Pipeline Velocity

36/100

Mech. Concentration

17/100

Completion Rate

84/100

Attrition Rate

11/100

Competition

Competitive Landscape

Bubble size = clinical trials

Approved
Phase 3
Phase 2
Phase 1
Preclinical

Key Players

Top Companies Companies ranked by the number of pipeline programs they run for this disease.

Eli Lilly logo

Eli Lilly

1 program

Phase 2Eisai logo

Eisai

1 program

Phase 2C

Cidara Therapeutics Inc., a subsidiary of Merck & Co., Inc. (Rahway, New Jersey USA)

1 program

Phase 2T

Taisho Pharmaceutical Co., Ltd.

1 program

Phase 3P

Purdue Pharma LP

1 program

ApprovedM

McNeil Consumer & Specialty Pharmaceuticals, a Division of McNeil-PPC, Inc.

1 program

Approved

Pipeline

Programs by Phase

Analysis

Trial Status

84

clinical trials

Completed48 · 57%
Recruiting13 · 15%
Not yet recruiting8 · 10%
Terminated5 · 6%
Withdrawn4 · 5%
Active, not recruiting3 · 4%
Other3 · 4%

Clinical Trials

Trial Activity

84 trials

The Effects of Lemborexant on the Ability to Sleep During Daytime
Recruiting·CCentre Integre Universitaire de Sante et Services Sociaux du Nord de l'ile de Montreal·Phase 2·NCT06231641·24 enrolled
ISP-001: Sleeping Beauty Transposon-Engineered B Cells for MPS I
Recruiting·IImmusoft of CA, Inc.·Phase 1·NCT05682144·2 enrolled
Mechanisms of Cannabidiol in Persons With MS: the Role of Sleep and Pain Phenotype
Recruiting·—·Phase 2·NCT05269628·166 enrolled
Evaluating the Effects of Tasimelteon Vs. Placebo in Delayed Sleep-Wake Phase Disorder (DSWPD) and the CRY1Δ11 Variant
Recruiting·VVanda Pharmaceuticals·Phase 3·NCT06701396·60 enrolled
Evaluating the Effects of Tasimelteon vs. Placebo in Delayed Sleep-Wake Phase Disorder (DSWPD)
Recruiting·VVanda Pharmaceuticals·Phase 3·NCT04652882·70 enrolled
Sleep Trial to Prevent Alzheimer's Disease
Recruiting·WWashington University School of Medicine·Phase 2·NCT04629547·120 enrolled
Sleep Treatment for Teens
Recruiting·RRutgers, The State University of New Jersey·Preclinical·NCT07303959·80 enrolled
Use of Magnesium-L-Threonate to Improve Subjective Sleep Quality After Total Joint Arthroplasties: Randomized Controlled Clinical Trial
Recruiting·UUniversity of Miami·Approved·NCT06902285·64 enrolled
Enhance the Restorative Power of Sleep Through TES-TI Power Naps
Recruiting·UUniversity of Wisconsin, Madison·Preclinical·NCT07090135·25 enrolled
Sleep Promotion Among Children Newly Diagnosed With Essential Hypertension
Recruiting·CChildren's Hospital of Philadelphia·Preclinical·NCT06642246·10 enrolled
Effects of Morning Bright Light Therapy on Sleep, Alertness, Mood, and Cognition in Healthy University Students: A Randomized Crossover Trial
Recruiting·TThe Hong Kong Polytechnic University·Preclinical·NCT07685262·153 enrolled
I-SLEPT: Integrated Sleep and Life Engagement Program for Transitions
Recruiting·VVA Office of Research and Development·Preclinical·NCT07317336·60 enrolled
Strategies to Augment Ketosis: Ketone Conferred Resiliency Against Sleep Restriction With Nutritional Intervention (STAK - Sleep + Feed)
Recruiting·OOhio State University·Preclinical·NCT06075914·60 enrolled
Effect of PXS-4728A on Microglia Activation in Participants With Isolated Rapid Eye Movement Sleep Behaviour Disorder
Active, not recruiting·SSyntara·Phase 2·NCT05904717·40 enrolled
Sleep and Inflammatory Resolution Pathway
Active, not recruiting·—·Phase 1·NCT03377543·66 enrolled
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Data sources: ClinicalTrials.gov (NIH) · OpenFDA (FDA) · ChEMBL (EMBL-EBI) · Open Targets (EBI/Sanger) · MedlinePlus (NIH) · PubMed (NIH) · SEC EDGAR (SEC)