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Other/Sleep

Sleep

12

Pipeline Programs↗

49

Active Trials↗

29

Companies Involved↗

Sleep is an emerging landscape with 12 programs across 29 companies. The most active players are Vanda Pharmaceuticals. 3 programs are in Phase 3.

Intelligence

Pipeline Metrics

Competitive Density

54/100

Pipeline Velocity

60/100

Mech. Concentration

33/100

Completion Rate

87/100

Attrition Rate

7/100

Competition

Competitive Landscape

Bubble size = clinical trials

Approved

Phase 3

Phase 2

Phase 1

Preclinical

Key Players

Top Companies

Vanda Pharmaceuticals

1 program

Pipeline

Programs by Phase

Preclinical6

Ketamine Hydrochloride

Boehringer Ingelheim

Remimazolam

Acacia Pharma Ltd

Propofol

Fresenius Kabi USA, LLC

Ghrelin

University of Aarhus

Menthol

GSK

Phase 11

Aspirin

Bayer

Phase 22

Suvorexant

Cidara Therapeutics Inc., a subsidiary of Merck & Co., Inc. (Rahway, New Jersey USA)

PXS-4728 (a)

Syntara

Phase 33

UBT251

Novo Nordisk

Magnesium Threonate

University of Miami

Tasimelteon

Vanda Pharmaceuticals

Approved

No programs

Analysis

Trial Status

121

clinical trials

Completed61 · 50%

Recruiting22 · 18%

Not yet recruiting20 · 17%

Terminated5 · 4%

Active, not recruiting5 · 4%

Withdrawn4 · 3%

Other4 · 3%

Clinical Trials

Trial Activity

121 trials

Evaluating the Effects of Tasimelteon Vs. Placebo in Delayed Sleep-Wake Phase Disorder (DSWPD) and the CRY1Δ11 Variant

Recruiting·VVanda Pharmaceuticals·Phase 3·NCT06701396·60 enrolled

The Effects of Lemborexant on the Ability to Sleep During Daytime

Recruiting·CCentre Integre Universitaire de Sante et Services Sociaux du Nord de l'ile de Montreal·Phase 2·NCT06231641·24 enrolled

The NANIT Insights Study: Impact of Smart Baby Monitor Technology on Infant Sleep and Parental Well-being in First-Time Parents - A Randomized Controlled Trial

Recruiting·UUdisense DBA Nanit·Preclinical·NCT07812896·200 enrolled

A Sleep Promotion Program for Depressed Adolescents in Pediatric Primary Care

Recruiting·UUniversity of Pittsburgh·Preclinical·NCT06240325·100 enrolled

Assessment of Postoperative Pain Outcomes Following Pediatric Adenotonsillectomy and the Impact on Non-Steroidal Anti-Inflammatory Drugs

Recruiting·BBaylor College of Medicine·N/A·NCT07672418·200 enrolled

A Sleep Hygiene Intervention to Improve Sleep Health in Urban, Latino Middle School Children

Recruiting·RRhode Island Hospital·Preclinical·NCT06942455·300 enrolled

Remimazolam and Postoperative Sleep in Elderly Patients Undergoing Laparoscopic Colorectal Cancer Resection: A Randomized, Double-Blind, PSG-Based Controlled Trial

Recruiting·GGeneral Hospital of Ningxia Medical University·Preclinical·NCT07740343·84 enrolled

DREAM-COUPLES: A Dyadic Multidimensional Sleep Health Intervention

Recruiting·CColumbia University·Preclinical·NCT07603245·50 enrolled

Sleep Promotion Among Children Newly Diagnosed With Essential Hypertension

Recruiting·CChildren's Hospital of Philadelphia·Preclinical·NCT06642246·10 enrolled

Enhance the Restorative Power of Sleep Through TES-TI Power Naps

Recruiting·UUniversity of Wisconsin, Madison·Preclinical·NCT07090135·25 enrolled

Night Owl Sleep Study: The Effect of Sleep on Fecal Microbiota

Recruiting·DDanisco·Preclinical·NCT07243574·174 enrolled

Sleep Duration and Cardiovascular Health

Recruiting·OOregon Health and Science University·Preclinical·NCT04804124·24 enrolled

The Effects of Sleep on Human Microbiota: Implications for Health and Disease

Recruiting·MMayo Clinic·Preclinical·NCT02573753·5,000 enrolled

Impact of Sleep Restriction on Blood Pressure Reactivity

Recruiting·UUniversity of Missouri-Columbia·Preclinical·NCT07489417·45 enrolled

Generative AI for Sleep Promotion

Recruiting·NNew York University·Preclinical·NCT07718750·60 enrolled

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Data sources: ClinicalTrials.gov (NIH) · OpenFDA (FDA) · ChEMBL (EMBL-EBI) · Open Targets (EBI/Sanger) · MedlinePlus (NIH) · PubMed (NIH) · SEC EDGAR (SEC)