VivoSeq
Other

Tremor

20

Pipeline Programs↗

3

Active Trials↗

10

Companies Involved↗

Tremor is an emerging landscape with 20 programs across 10 companies. The most active players are Jazz Pharmaceuticals, Merz Pharmaceuticals GmbH, Astellas. 3 therapies are approved with 2 more in late-stage development.

Intelligence

Pipeline Metrics

Competitive Density

47/100

Pipeline Velocity

11/100

Mech. Concentration

11/100

Completion Rate

89/100

Attrition Rate

8/100

Competition

Competitive Landscape

Bubble size = clinical trials

Approved
Phase 3
Phase 2
Phase 1
Preclinical

Key Players

Top Companies Companies ranked by the number of pipeline programs they run for this disease.

Jazz Pharmaceuticals logo

Jazz Pharmaceuticals

4 programs

Phase 2M

Merz Pharmaceuticals GmbH

1 program

Phase 2Astellas logo

Astellas

1 program

Phase 2Lundbeck logo

Lundbeck

1 program

Phase 2V

Viatris Specialty LLC

1 program

Phase 3M

McNeil Consumer & Specialty Pharmaceuticals, a Division of McNeil-PPC, Inc.

1 program

Approved

Pipeline

Programs by Phase

Analysis

Trial Status

25

clinical trials

Completed17 · 68%
Unknown status3 · 12%
Recruiting2 · 8%
Withdrawn1 · 4%
Terminated1 · 4%
Not yet recruiting1 · 4%

Clinical Trials

Trial Activity

25 trials

A Cross Over Pilot Study of Abobotulinum Toxin A (Dysport) as a Treatment for Task-dependent Upper Limb Tremor
Recruiting·—·Phase 4·NCT03136341·25 enrolled
Deep Brain Stimulation of the Deep Cerebellar Nuclei for Refractory Tremor
Recruiting·TThe Cleveland Clinic·Phase 1·NCT07049003·12 enrolled
Extended-release Sodium Oxybate (Lumryz) in Spasmodic Dysphonia and Voice Tremor
Not yet recruiting·—·Phase 1·NCT07041203·8 enrolled
Comparison of Botulinum Toxin Injections in Forearm FLexor Plus EXtensor Muscles vs. Flexor Muscles Alone for Treatment of Essential Hand Tremor(FLEX-D ET)
Completed·TThe Cleveland Clinic·N/A·NCT02909907·21 enrolled
Sodium Oxybate in Spasmodic Dysphonia and Voice Tremor
Completed·—·Phase 2/3·NCT03292458·117 enrolled
Investigation of the Efficacy and Safety of IncobotulinumtoxinA (Xeomin) in Parkinson's Tremor: A Customized Approach
Completed·YYale University·Phase 2·NCT02419313·33 enrolled
Effect of Alcohol on Tremors
Completed·National Institute of Neurological Disorders and Stroke (NINDS)·Phase 2·NCT00001925·23 enrolled
A Study of Suvecaltamide in Adults With Moderate to Severe Residual Tremor in Parkinson's Disease
Completed·Jazz Pharmaceuticals logoJazz Pharmaceuticals·Phase 2·NCT05642442·169 enrolled
Functional Imaging of Tremor Circuits and Mechanisms of Treatment Response
Completed·UUniversity of California, San Diego·Phase 4·NCT02495883·56 enrolled
Voice Tremor in Spasmodic Dysphonia: Central Mechanisms and Treatment Response
Completed·—·Phase 2·NCT01961297·53 enrolled
Essential Voice Tremor: A Study of Botulinum Toxin Treatment and Injection Augmentation
Completed·WWeill Medical College of Cornell University·N/A·NCT02711995·8 enrolled
The Effect of Sifrol® on Tremor and Depression in Patients With Idiopathic Parkinson's Disease
Completed·Boehringer Ingelheim logoBoehringer Ingelheim·N/A·NCT02231294·1,464 enrolled
Botulinum Toxin A to Treat Arm Tremor
Completed·MMerz Pharmaceuticals GmbH·Phase 2·NCT02207946·30 enrolled
Effectiveness of Botox on Reducing Rest Tremor in Parkinson's Disease
Completed·UUniversity of North Carolina, Chapel Hill·Phase 2·NCT03301272·16 enrolled
A Comparison of the Efficacy and Safety of Topiramate Versus Placebo in Treating Tremor of Unknown Cause.
Completed·Johnson & Johnson Pharmaceutical Research & Development, L.L.C. logoJohnson & Johnson Pharmaceutical Research & Development, L.L.C.·Phase 3·NCT00236496·223 enrolled
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Data sources: ClinicalTrials.gov (NIH) · OpenFDA (FDA) · ChEMBL (EMBL-EBI) · Open Targets (EBI/Sanger) · MedlinePlus (NIH) · PubMed (NIH) · SEC EDGAR (SEC)