amoxicillin/clavulanate

ApprovedSmall molecule

Bayer

amoxicillin/clavulanate is one of 115 small molecule programs targeting Sinusitis. It is currently in Approved.

Indications

Total Trials

Active Trials

114

Competitors

Pipeline

Status by Indication[3][1]

Indication

SinusitisActive, not recruiting

PneumoniaActive, not recruiting

Urinary Tract InfectionActive, not recruiting

SinusitisApproved

Active, not recruiting

PneumoniaPhase 3

Active, not recruiting

Urinary Tract InfectionPhase 3

Active, not recruiting

Competition

Competitive Landscape

547 competitors in Pneumonia

#DrugCompanyPhaseTrials

amoxicillin/clavulanate

Bayer

Approved

2 2

Primaxin

Pfizer

Preclinical

2 3

Jakafi

Incyte

Preclinical

1 4

Primaquine

Sanofi

Preclinical

1 5

Acanya

Pfizer

Preclinical

1 6

Prevacid

Takeda

Preclinical

1 7

Innohep

Alnylam Pharmaceuticals

Preclinical

1 8

Avlosulfon

AAlmirall, S.A.

Preclinical

4 9

Neutrexin

WWest Japan Thoracic Oncology Group

Preclinical

12 10

Virazole

CConrado Roberto Hoffmann Filho

Preclinical

Ranked by pipeline maturity and clinical activity. Current drug highlighted in teal.

Timeline

Expected Milestones

Q2 2027

Phase 3Recruiting

Pneumonia

NCT06229288

Q3 2027

Post-ApprovalRecruiting

Antibiotic Prophylaxis

NCT05846399

Clinical

Trials by Indication[1]

Sinusitis3 trials

Comparison Study Between Cefdinir & Amoxicilline/Clavulanate in Acute Sinusitis and Assessment of Quality of Life

Completed·UUniversity of Chicago·Phase 4·NCT00147914·100 enrolled

Study to Evaluate the Efficacy and Safety of Moxifloxacin Versus Amoxicillin/Clavulanate in the Treatment of Acute Bacterial Rhinosinusitis

Terminated· Bayer logo

Bayer·Phase 4·NCT00493038·293 enrolled

Zmax Compared to Augmentin in Sinusitis

Completed· Pfizer logo

Pfizer·Phase 4·NCT00367120·762 enrolled

Antibiotic Prophylaxis2 trials

CAT BITE Antibiotic Prophylaxis for the Hand/Forearm (CATBITE)

Recruiting·UUniversity of Missouri-Columbia·Phase 4·NCT05846399·72 enrolled

The Impact of Antibiotic Prophylaxis on Incidence of Post-bronchoscopy Fever and Change of Serum Cytokines

Completed·SSeoul National University Hospital·Phase 4·NCT01089218·241 enrolled

Pneumonia2 trials

Azithromycin+Amoxicillin/Clavulanate vs Amoxicillin/Clavulanate in COVID19 Patients With Pneumonia in Non-intensive Unit

Unknown status·NNantes University Hospital·Phase 3·NCT04363060·104 enrolled

Amoxicillin Alone Versus Amoxicillin/Clavulanate for Community-acquired Pneumonia in Patients Aged 65 Years or Older, and Hospitalized in a Non-intensive Care Unit Ward

Recruiting·NNantes University Hospital·Phase 3·NCT06229288·326 enrolled

Intra-abdominal Infection1 trial

Moxifloxacin in Pediatric Subjects With Complicated Intra-abdominal Infection

Completed· Bayer logo

Bayer·Phase 3·NCT01069900·458 enrolled

Infections1 trial

AUGMENTIN™ in Dental Infections

Completed· GSK logo

GSK·Phase 4·NCT02141217·472 enrolled

2 more indications

Urinary Tract Infection1 trial

Oral Sulopenem Versus Amoxicillin/Clavulanate for Uncomplicated Urinary Tract Infection in Adult Women

Completed·IIterum Therapeutics, International Limited·Phase 3·NCT05584657·2,229 enrolled

Tonsillectomy1 trial

Role of Antibiotics Post Tonsillectomy

Unknown status·—·Phase 1/2·NCT03491085·200 enrolled

Sources

References

[1]
ClinicalTrials.gov — 11 trial records for amoxicillin/clavulanate. U.S. National Library of Medicine, National Institutes of Health.
[2]
ChEMBL — amoxicillin/clavulanate compound record. European Bioinformatics Institute (EMBL-EBI).
[3]
Open Targets Platform — Drug–disease associations for amoxicillin/clavulanate. EMBL-EBI & Wellcome Sanger Institute.
[4]
SEC EDGAR — Bayer company filings. U.S. Securities and Exchange Commission.

Details

Drug Info

Quick Facts

Modality: Small molecule[2]
Highest Phase: Approved[1]
Company: Bayer

amoxicillin/clavulanate

Status by Indication[3][1]

Competitive Landscape

Expected Milestones

Q2 2027

Q3 2027

Trials by Indication[1]

Sinusitis3 trials

Antibiotic Prophylaxis2 trials

Pneumonia2 trials

Intra-abdominal Infection1 trial

Infections1 trial

Urinary Tract Infection1 trial

Tonsillectomy1 trial

References

Drug Info

Quick Facts

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