Acanya

(clindamycin)

ApprovedSmall molecule

This medication combines an antibiotic and an antibacterial agent to treat acne by killing the bacteria responsible for the condition. It comes as a gel applied directly to the skin.[2] Acanya is currently approved and in use across 33 indications[4].[1]

Acanya is one of 471 small molecule programs targeting Peritonsillar Abscess. It is currently in Approved.

Indications

Total Trials

Active Trials

470

Competitors

FDA Applications

NDA/BLA/ANDA regulatory filings

Patents

Pipeline

Status by Indication[4][1]

Indication

Peritonsillar AbscessActive, not recruiting

Bacterial DiseaseActive, not recruiting

Dermatitis, PerioralActive, not recruiting

AcneActive, not recruiting

Staphylococcal Skin InfectionsActive, not recruiting

EndometritisActive, not recruiting

Breast NeoplasmActive, not recruiting

Anal FistulaActive, not recruiting

OsteomyelitisActive, not recruiting

Hidradenitis SuppurativaActive, not recruiting

Peritonsillar AbscessPreclinical

Active, not recruiting

Bacterial DiseaseApproved

Active, not recruiting

Dermatitis, PerioralPreclinical

Active, not recruiting

AcneApproved

Active, not recruiting

Staphylococcal Skin InfectionsPreclinical

Active, not recruiting

EndometritisApproved

Active, not recruiting

Breast NeoplasmPreclinical

Active, not recruiting

Anal FistulaPreclinical

Active, not recruiting

OsteomyelitisApproved

Active, not recruiting

Hidradenitis SuppurativaPreclinical

Active, not recruiting

Showing 10 of 33 indications

Competition

Competitive Landscape

744 competitors in Breast Cancer

#DrugCompanyPhaseTrials

Acanya

Pfizer

Approved

71 2

Blenoxane

Bristol-Myers Squibb

Preclinical

1 3

Neoadjuvant Treatment

SShanghai Zhongshan Hospital

Preclinical

1 4

Tianeptine

Pfizer

Preclinical

1 5

Metfomin

UUniversity of Texas Southwestern Medical Center

Preclinical

1 6

Diuretic

RReprieve Cardiovascular, Inc

Preclinical

1 7

Recombinant Human Endostatin

PPeking University Third Hospital

Preclinical

1 8

Bisphosphonate

Amgen

Preclinical

2 9

Naltrexone/bupropion

Novo Nordisk

Preclinical

1 10

Perflutren Lipid Microsphere

IImaRx Therapeutics

Preclinical

Ranked by pipeline maturity and clinical activity. Current drug highlighted in teal.

Timeline

Expected Milestones

Q4 2026

Phase 2Not yet recruiting

Cardiac Surgery

NCT07267013

N/ANot yet recruiting

Infection

NCT06702345

Q1 2027

PreclinicalNot yet recruiting

Odontogenic Infection

NCT07810244

Q3 2027

Post-ApprovalRecruiting

Antibiotic Prophylaxis

NCT05846399

Q4 2027

ApprovedRecruiting

Endocarditis

NCT05398679

Clinical

Trials by Indication[1]

Antibiotics4 trials

Or v IV Antibiotics for Infection

Unknown status·RRothman Institute Orthopaedics·Phase 3·NCT04723940·308 enrolled

Effect of Antibiotics on Penile Microbiome and HIV Susceptibility Study in Ugandan Men

Unknown status·UUniversity of Toronto·N/A·NCT03412071·125 enrolled

Strategies Using Off-Patent Antibiotics for Methicillin Resistant S. Aureus "STOP MRSA"

Completed·NNational Institute of Allergy and Infectious Diseases (NIAID)·Phase 2/3·NCT00729937·2,265 enrolled

Show 1 more trial

Antibiotics Usage in Pediatric Orthopaedic Percutaneous Surgery (APOPS)

Completed·SSumit Gupta·Phase 4·NCT03261830·160 enrolled

Bacterial Vaginosis3 trials

Comparative Study of Efficacy of 10 mg Dequalinium Chloride (Fluomizin) in the Local Treatment of Bacterial Vaginosis

Completed·MMedinova AG·Phase 3·NCT01125410·321 enrolled

Prevention of Very Preterm Delivery by Testing for and Treatment of Bacterial Vaginosis

Completed·UUniversity Hospital, Lille·Phase 4·NCT00642980·3,105 enrolled

Vaginal Clindamycin Cream Plus Vaginal Probiotic for Bacterial Vaginosis

Unknown status·ZZagazig University·Phase 2·NCT03234517·200 enrolled

Safety and Efficacy3 trials

A Clinical Study Evaluating the Safety and Efficacy of IDP-110 in Patients With Acne Vulgaris

Completed·DDow Pharmaceutical Sciences·Phase 3·NCT00664248·1,414 enrolled

Safety and Efficacy Study of Clindamycin/Benzoyl Peroxide/Tazarotene Cream in Subjects With Acne

Completed· GSK logo

GSK·Phase 2·NCT00713609·591 enrolled

A Clinical Trial Evaluating the Safety and Efficacy of IDP-110 in Patients With Acne Vulgaris

Completed·DDow Pharmaceutical Sciences·Phase 3·NCT00663286·1,399 enrolled

Antibiotic Prophylaxis2 trials

Antibiotic Prophylaxis for Simple Hand Lacerations

Terminated·SState University of New York - Downstate Medical Center·N/A·NCT01155154·73 enrolled

CAT BITE Antibiotic Prophylaxis for the Hand/Forearm (CATBITE)

Recruiting·UUniversity of Missouri-Columbia·Phase 4·NCT05846399·72 enrolled

Treatment2 trials

Optimal Treatment of MRSA Throat Carriers

Completed·HHvidovre University Hospital·Phase 3·NCT04104178·53 enrolled

A Phase III Comparative Study of Dapsone / Trimethoprim and Clindamycin / Primaquine Versus Sulfamethoxazole / Trimethoprim in the Treatment of Mild-to-Moderate PCP in Patients With AIDS

Completed·NNational Institute of Allergy and Infectious Diseases (NIAID)·Phase 3·NCT00000640·290 enrolled

50 more indications

Skin Infection2 trials

Asymptomatic Colonization With S. Aureus After Therapy With Linezolid or Clindamycin for Acute Skin Infections

Terminated·UUniversity of Chicago·N/A·NCT01619410·25 enrolled

Comparison of Cephalexin Versus Clindamycin for Suspected CA-MRSA Skin Infections

Completed·AAaron Chen·Phase 4·NCT00352612·200 enrolled

Randomized Controlled Trial2 trials

Adjunctive Clindamycin for the Treatment of Skin and Soft Tissue Infections, a Randomized Controlled Trial

Recruiting·FFrieder Schaumburg·Phase 4·NCT05899140·100 enrolled

Prophylactic Antibiotics for Manual Removal of Retained Placenta in Vaginal Birth: a Randomized Controlled Trial

Unknown status·HHadassah Medical Organization·N/A·NCT01945450·300 enrolled

Abscess2 trials

Aspiration Treatment of Perianal Abscess

Completed·UUniversity of Southern Denmark·N/A·NCT02585141·111 enrolled

Randomized Controlled Trial of Antibiotics in the Management of Children With Community-Acquired Abscess

Terminated·—·N/A·NCT01498744·53 enrolled

Methicillin-resistant Staphylococcus Aureus2 trials

Study Evaluating Tigecycline Versus Clindamycin Or Vancomycin On Complicated Skin And Skin Structure Infections Including Those Due To Methicillin-Resistant Staphylococcus Aureus (MRSA) In Pediatric Subjects

Withdrawn· Pfizer logo

Pfizer·Phase 3·NCT00911573

Uncomplicated Skin and Soft Tissue Infections Caused by Community-Associated Methicillin-Resistant Staphylococcus Aureus

Completed·NNational Institute of Allergy and Infectious Diseases (NIAID)·Phase 2·NCT00730028·1,310 enrolled

Encephalitis2 trials

Toxoplasmic Encephalitis in Patients With AIDS. Treatment and Prevention of Relapse

Completed·PPalo Alto Medical Foundation·N/A·NCT00002064

A Pilot Study of Oral Clindamycin and Pyrimethamine for the Treatment of Toxoplasmic Encephalitis in Patients With AIDS

Completed·NNational Institute of Allergy and Infectious Diseases (NIAID)·N/A·NCT00000674·30 enrolled

Infections2 trials

Dalbavancin for the Treatment of Acute Bacterial Skin and Skin Structure Infections in Children, Known or Suspected to be Caused by Susceptible Gram-positive Organisms, Including MRSA

Completed· AbbVie logo

AbbVie·Phase 3·NCT02814916·199 enrolled

AUGMENTIN™ in Dental Infections

Completed· GSK logo

GSK·Phase 4·NCT02141217·472 enrolled

Prosthetic-joint Infection2 trials

Rifampicin Combination Therapy Versus Monotherapy for Staphylococcal Prosthetic Joint Infection

Recruiting·LLeiden University Medical Center·Phase 4·NCT06172010·316 enrolled

Efficacy and Safety Study of Antibiotic Treatment to Treat Hip Prosthetic Joint Infection

Unknown status·UUniversity Hospital, Tours·Phase 2·NCT01757236·100 enrolled

Pneumonia1 trial

The Safety and Efficacy of Clindamycin and Primaquine in the Treatment of Mild - Moderate Pneumocystis Carinii Pneumonia in Patients With AIDS

Completed·NNational Institute of Allergy and Infectious Diseases (NIAID)·N/A·NCT00000717·50 enrolled

Preterm Birth1 trial

Clindamycin to Reduce Preterm Birth in a Low Resource Setting

Completed·CChristiana Care Health Services·Phase 4·NCT01800825·1,726 enrolled

Children1 trial

PK of Clindamycin and Trimethoprim-sulfamethoxazole in Infants and Children

Completed·MMichael Cohen-Wolkowiez·Phase 1·NCT02475876·51 enrolled

Cellulitis1 trial

Adjunctive Clindamycin for Cellulitis: C4C Trial.

Completed·UUniversity Hospitals Bristol and Weston NHS Foundation Trust·Phase 4·NCT01876628·410 enrolled

Colonization1 trial

S. Aureus Decolonization in HPN Patients.

Terminated·RRadboud University Medical Center·N/A·NCT03173053·63 enrolled

Randomized1 trial

Trial of Randomized Antibiotic Administration in Percutaneous Nephrolithotomy

Completed·NNorthwell Health·Phase 3·NCT02579161·98 enrolled

Staphylococcus Aureus1 trial

Staphylococcus Aureus Network Adaptive Platform Trial

Recruiting·UUniversity of Melbourne·Phase 4·NCT05137119·8,000 enrolled

Cardiac Surgery1 trial

Clindamycin as an Alternative to Vancomycin in Patients Undergoing Aortic Cardiac Surgery With Extracorporeal Circulation (ECC)

Not yet recruiting·NNantes University Hospital·Phase 2·NCT07267013·25 enrolled

Concentration1 trial

A Randomized, Controlled Trial of the Effectiveness of Perioperative Antibiotics for Reduction of Burn Wound Bacterial Concentration Following Grafting

Completed·MMedstar Health Research Institute·Phase 4·NCT04516148·32 enrolled

Clindamycin Vs Metronidazole1 trial

Comparison Between Oral Clindamycin Vs Metronidazole for the Treatment of Abnormal Vaginal Flora in High Risk Pregnancies

Completed·HHaEmek Medical Center, Israel·N/A·NCT01722708·166 enrolled

Urinary Tract Infection1 trial

Prophylactic Antibiotics for Urinary Tract Infections After Robot-Assisted Radical Cystectomy

Completed·RRoswell Park Cancer Institute·Phase 4·NCT04502095·89 enrolled

Trial1 trial

Trial of Clindamycin / Benzoyl Peroxide Gel in Subjects With Acne

Completed· GSK logo

GSK·Phase 3·NCT00776919·1,315 enrolled

Fed1 trial

Clindamycin 300 mg Capsules in Healthy Subjects Under Fed Conditions

Completed· Teva logo

Teva·Phase 1·NCT00836004·24 enrolled

Fasting Conditions1 trial

Clindamycin 300 mg Capsules in Healthy Subjects Under Fasting Conditions

Completed· Teva logo

Teva·Phase 1·NCT00836056·24 enrolled

Antibiotic1 trial

Short Versus Standard of Care Antibiotic Duration for Children Hospitalized for CAP

Recruiting·MMedical College of Wisconsin·Phase 4·NCT06494072·236 enrolled

Periodontitis1 trial

Efficacy of Amoxicillin-metronidazole Compared to Clindamycin in Patients With Periodontitis and Diabetes

Completed·CCentro Universitario de Tonalá·Phase 3·NCT03374176·42 enrolled

Neurosurgery1 trial

The Potential Impact of Clindamycin on Neurosurgery Patients.

Completed·—·N/A·NCT06068673·44 enrolled

Preoperative1 trial

Effect of Preoperative Clindamycin on Postoperative Endodontic Pain

Unknown status·—·Phase 2/3·NCT03033472·72 enrolled

Effectiveness1 trial

A Clinical Study to Evaluate the Safety and Effectiveness of an Investigational Product Called CT Gel

Completed· GSK logo

GSK·Phase 3·NCT00689117·1,649 enrolled

Cesarean Section1 trial

Preoperative Clindamycin Vaginal Cream Versus Vaginal Cleansing With Povidone-iodine on Postoperative Infections After Cesarean Section

Recruiting·—·Phase 4·NCT07474194·150 enrolled

Critical Care1 trial

Drug Use Evaluation of Clindamycin in Critical Care Units in Alexandria Main University Hospital

Completed·—··NCT05223400·99 enrolled

Dental Implant1 trial

Clindamycin Versus Amoxicillin With Clavulanic Acid in Prevention of Early Dental Implants Failure

Unknown status·JJordan University Hospital·Phase 1·NCT04980170·100 enrolled

Efficacy and Safety1 trial

A Study to Evaluate the Efficacy and Safety of Adapalene-Clindamycin Combination Gel in the Treatment of Acne Vulgaris

Completed·LLee's Pharmaceutical Limited·Phase 3·NCT03615768·1,617 enrolled

Skin rash1 trial

Skin Rash Study Before Chemotherapy in Colorectal & Head and Neck Cancer Patients

Completed·UUniversity of Louisville·Phase 2·NCT01874860·24 enrolled

Infection1 trial

Clostridioides Difficile Controlled Human Infection Model

Not yet recruiting·LLeiden University Medical Center·N/A·NCT06702345·60 enrolled

Septic Abortion1 trial

Clindamycin Once a Day in Septic Abortion

Completed·HHospital de Clinicas de Porto Alegre·Phase 4·NCT02309346·202 enrolled

Malaria1 trial

Efficacy of Fosmidomycin-Clindamycin for Treating Malaria in Gabonese Children

Completed·—·Phase 3·NCT00214643·160 enrolled

Peritonsillar Abscess1 trial

Assessing the Necessity of Prescribing Antibiotics (Clavulin or Clindamycin Versus Placebo) Post-peritonsillar Abscess Drainage

Withdrawn·LLondon Health Sciences Centre Research Institute OR Lawson Research Institute of St. Joseph's·N/A·NCT01715610

Microbiota1 trial

The Effect of Clindamycin and a Live Biotherapeutic on the Reproductive Outcomes of IVF Patients With Abnormal Vaginal Microbiota

Unknown status·PPeter Humaidan·Phase 2·NCT05166746·333 enrolled

Staphylococcus Aureus Bacteremia1 trial

Staphylococcus Aureus Bacteremia Antibiotic Treatment Options

Completed·HHeinrich-Heine University, Duesseldorf·Phase 3·NCT01792804·215 enrolled

Dermatitis1 trial

Laser Therapy for Perioral Dermatitis

Withdrawn·WWest Virginia University·N/A·NCT03779295

Metabolic Syndrome1 trial

Interventional Bioremediation of Microbiota in Metabolic Syndrome

Terminated·UUniversity of Minnesota·Phase 2·NCT02730962·12 enrolled

Streptococcal Infections1 trial

Adjunctive Clindamycin Versus Linezolid for β-lactam Treated Patients With Invasive Group A Streptococcal Infections

Unknown status·NNational Institutes of Health Clinical Center (CC)··NCT06126263·1,000 enrolled

Acne Vulgaris1 trial

Bio-equivalence Study With Clinical Endpoints in the Treatment of Acne Vulgaris

Completed· Sun Pharmaceutical Industries, Inc. logo

Sun Pharmaceutical Industries, Inc.·Phase 1·NCT04134273·1,260 enrolled

Pediatric1 trial

Safety and Pharmacokinetics of Clindamycin in Pediatric Subjects With BMI ≥ 85th Percentile

Completed·PPhillip Brian Smith·Phase 1·NCT01744730·22 enrolled

Amputation1 trial

The Amputation Surgical Site Infection Trial (ASSIT)

Completed·HHull University Teaching Hospitals NHS Trust·Phase 4·NCT02018094·160 enrolled

Bacteremia1 trial

An Oral Doxycycline Regimen to Prevent Bacteremia Following Dental Procedures

Not yet recruiting·UUniversity of Santiago de Compostela·Phase 4·NCT06422221·150 enrolled

Odontogenic Infection1 trial

Moxifloxacin Versus Clindamycin in the Management of Odontogenic Maxillofacial Infectious Processes: A Preliminary, Intrahospital, Controlled Clinical Trial

Not yet recruiting·NNishtar Medical University·Preclinical·NCT07810244·60 enrolled

Joint Infection1 trial

Randomized Open-label Active-controlled Study to Assess the Safety, Tolerability, and Efficacy of Afabicin IV/Oral in the Treatment of Patients With Bone or Joint Infection Due to Staphylococcus

Terminated·DDebiopharm International SA·Phase 2·NCT03723551·67 enrolled

Carcinoma, Non-Small-Cell Lung1 trial

A Phase 2, Open-Label, Randomized Trial Evaluating the Impact of Enhanced Versus Standard Dermatologic Management on Selected Dermatologic Adverse Events Among Patients With Locally Advanced or Metastatic EGFR-Mutated NSCLC Treated First-Line With Amivantamab + Lazertinib

Active, not recruiting· Johnson & Johnson logo

Johnson & Johnson·Phase 2·NCT06120140·305 enrolled

Lactating Women on Select DOI1 trial

Pharmacokinetics and Safety of Commonly Used Drugs in Lactating Women and Breastfed Infants

Recruiting·DDuke University··NCT03511118·1,600 enrolled

Endocarditis1 trial

Oral Antimicrobial Treatment vs. Outpatient Parenteral for Infective Endocarditis

Recruiting·FFundacion Clinic per a la Recerca Biomédica·Approved·NCT05398679·360 enrolled

Unspecified1 trial

Dalacin-T Gel Post Approval Study

Completed· Pfizer logo

Pfizer·Phase 4·NCT00219570·134 enrolled

Regulatory

FDA Approval Timeline[5]

Jan 1, 1982

CLEOCIN PHOSPHATE

NDA NDA050441

Jan 1, 1982

CLEOCIN T

NDA NDA050537

Jan 1, 1982

CLEOCIN HYDROCHLORIDE

NDA NDA050162

Jan 7, 1987

CLEOCIN T

NDA NDA050615

May 31, 1989

CLEOCIN T

NDA NDA050600

Aug 30, 1989

CLEOCIN PHOSPHATE IN DEXTROSE 5% IN PLASTIC CONTAINER

NDA NDA050639

Dec 22, 1989

CLINDAMYCIN PHOSPHATE IN DEXTROSE 5%

NDA NDA050636

Dec 22, 1989

CLINDAMYCIN PHOSPHATE IN DEXTROSE 5%

NDA NDA050635

Dec 29, 1989

CLINDAMYCIN PHOSPHATE IN DEXTROSE 5% IN PLASTIC CONTAINER

NDA NDA050648

Aug 11, 1992

CLEOCIN

NDA NDA050680

Aug 13, 1999

CLEOCIN

NDA NDA050767

Nov 27, 2000

CLINDAGEL

NDA NDA050782

Oct 22, 2004

EVOCLIN

NDA NDA050801

Nov 30, 2004

CLINDESSE

NDA NDA050793

Apr 20, 2017

CLINDAMYCIN PHOSPHATE IN 0.9% SODIUM CHLORIDE

NDA NDA208083

Dec 7, 2021

XACIATO

NDA NDA215650

Sources

References

[1]
ClinicalTrials.gov — 71 trial records for clindamycin. U.S. National Library of Medicine, National Institutes of Health.
[2]
MedlinePlus Drug Information — Acanya drug information. U.S. National Library of Medicine, National Institutes of Health.
[3]
ChEMBL — clindamycin compound record. European Bioinformatics Institute (EMBL-EBI).
[4]
Open Targets Platform — Drug–disease associations for clindamycin. EMBL-EBI & Wellcome Sanger Institute.
[5]
OpenFDA — FDA approval records (NDA NDA215650). U.S. Food & Drug Administration.
[6]
FDA Orange Book — Patent and exclusivity data for Acanya. U.S. Food & Drug Administration.
[7]
SEC EDGAR — Pfizer company filings. U.S. Securities and Exchange Commission.

Details

Drug Info

Quick Facts

Mechanism of Action: Bacterial 70s Ribosome Inhibitor[3]
Modality: Small molecule[3]
Highest Phase: Approved[1]
Company: Pfizer

Patent Landscape[6]

Patent Cliff

Dec 2, 2026

Earliest patent expiration — generic entry possible after this date

Patent #Expires

9789057Dec 2, 2026

11129896Sep 22, 2036

12303563Sep 22, 2036

Acanya

Status by Indication[4][1]

Competitive Landscape

Expected Milestones

Q4 2026

Q1 2027

Q3 2027

Q4 2027

Trials by Indication[1]

Antibiotics4 trials

Bacterial Vaginosis3 trials

Safety and Efficacy3 trials

Antibiotic Prophylaxis2 trials

Treatment2 trials

Skin Infection2 trials

Randomized Controlled Trial2 trials

Abscess2 trials

Methicillin-resistant Staphylococcus Aureus2 trials

Encephalitis2 trials

Infections2 trials

Prosthetic-joint Infection2 trials

Pneumonia1 trial

Preterm Birth1 trial

Children1 trial

Cellulitis1 trial

Colonization1 trial

Randomized1 trial

Staphylococcus Aureus1 trial

Cardiac Surgery1 trial

Concentration1 trial

Clindamycin Vs Metronidazole1 trial

Urinary Tract Infection1 trial

Trial1 trial

Fed1 trial

Fasting Conditions1 trial

Antibiotic1 trial

Periodontitis1 trial

Neurosurgery1 trial

Preoperative1 trial

Effectiveness1 trial

Cesarean Section1 trial

Critical Care1 trial

Dental Implant1 trial

Efficacy and Safety1 trial

Skin rash1 trial

Infection1 trial

Septic Abortion1 trial

Malaria1 trial

Peritonsillar Abscess1 trial

Microbiota1 trial

Staphylococcus Aureus Bacteremia1 trial

Dermatitis1 trial

Metabolic Syndrome1 trial

Streptococcal Infections1 trial

Acne Vulgaris1 trial

Pediatric1 trial

Amputation1 trial

Bacteremia1 trial

Odontogenic Infection1 trial

Joint Infection1 trial

Carcinoma, Non-Small-Cell Lung1 trial

Lactating Women on Select DOI1 trial

Endocarditis1 trial

Unspecified1 trial

FDA Approval Timeline[5]

References

Drug Info

Quick Facts

Patent Landscape[6]

Related News